-
1
-
-
0008390266
-
The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity
-
USA
-
de Lecea L, Kilduff TS, Peyron C, Gao X, Foye PE, Danielson PE, Fukuhara C, Battenberg EL, Gautvik VT, Bartlett FS, Frankel WN, van den Pol AN, Bloom FE, Gautvik KM, Sutcliffe JG 1998 The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci USA 95:322-327
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 322-327
-
-
De Lecea, L.1
Kilduff, T.S.2
Peyron, C.3
Gao, X.4
Foye, P.E.5
Danielson, P.E.6
Fukuhara, C.7
Battenberg, E.L.8
Gautvik, V.T.9
Bartlett, F.S.10
Frankel, W.N.11
Van Den Pol, A.N.12
Bloom, F.E.13
Gautvik, K.M.14
Sutcliffe, J.G.15
-
2
-
-
20244380014
-
Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M 1998 Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92:573-585
-
(1998)
Cell
, vol.92
, pp. 573-585
-
-
Sakurai, T.1
Amemiya, A.2
Ishii, M.3
Matsuzaki, I.4
Chemelli, R.M.5
Tanaka, H.6
Williams, S.C.7
Richardson, J.A.8
Kozlowski, G.P.9
Wilson, S.10
Arch, J.R.11
Buckingham, R.E.12
Haynes, A.C.13
Carr, S.A.14
Annan, R.S.15
McNulty, D.E.16
Liu, W.S.17
Terrett, J.A.18
Elshourbagy, N.A.19
Bergsma, D.J.20
Yanagisawa, M.21
more..
-
4
-
-
1942440473
-
Expression of human prepro-orexin and signaling characteristics of orexin receptors in the male reproductive system
-
Karteris E, Chen J, Randeva HS 2004 Expression of human prepro-orexin and signaling characteristics of orexin receptors in the male reproductive system. J Clin Endocrinol Metab 89:1957-1962
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1957-1962
-
-
Karteris, E.1
Chen, J.2
Randeva, H.S.3
-
5
-
-
0032573385
-
Induction of outward current by orexin-B in mouse peritoneal macrophages
-
Ichinose M, Asai M, Sawada M, Sasaki K, Oomura Y 1998 Induction of outward current by orexin-B in mouse peritoneal macrophages. FEBS Lett 440:51-54
-
(1998)
FEBS Lett
, vol.440
, pp. 51-54
-
-
Ichinose, M.1
Asai, M.2
Sawada, M.3
Sasaki, K.4
Oomura, Y.5
-
6
-
-
29444446876
-
Primary human CD34+ hematopoietic stem and progenitor cells express functionally active receptors of neuromediators
-
Steidl U, Bork S, Schaub S, Selbach O, Seres J, Aivado M, Schroeder T, Rohr UP, Fenk R, Kliszewski S, Maercker C, Neubert P, Bornstein SR, Haas HL, Kobbe G, Tenen DG, Haas R, Kronenwett R 2004 Primary human CD34+ hematopoietic stem and progenitor cells express functionally active receptors of neuromediators. Blood 11:11-18
-
(2004)
Blood
, vol.11
, pp. 11-18
-
-
Steidl, U.1
Bork, S.2
Schaub, S.3
Selbach, O.4
Seres, J.5
Aivado, M.6
Schroeder, T.7
Rohr, U.P.8
Fenk, R.9
Kliszewski, S.10
Maercker, C.11
Neubert, P.12
Bornstein, S.R.13
Haas, H.L.14
Kobbe, G.15
Tenen, D.G.16
Haas, R.17
Kronenwett, R.18
-
7
-
-
0035954357
-
Normal plasma levels of orexin a (hypocretin-1) in narcoleptic patients
-
Dalal MA, Schuld A, Haack M, Uhr M, Geisler P, Eisensehr I, Noachtar S, Pollmacher T 2001 Normal plasma levels of orexin A (hypocretin-1) in narcoleptic patients. Neurology 56:1749-1751
-
(2001)
Neurology
, vol.56
, pp. 1749-1751
-
-
Dalal, M.A.1
Schuld, A.2
Haack, M.3
Uhr, M.4
Geisler, P.5
Eisensehr, I.6
Noachtar, S.7
Pollmacher, T.8
-
8
-
-
0037221707
-
Glucose regulates the release of orexin-a from the endocrine pancreas
-
Ouedraogo R, Naslund E, Kirchgessner AL 2003 Glucose regulates the release of orexin-a from the endocrine pancreas. Diabetes 52:111-117
-
(2003)
Diabetes
, vol.52
, pp. 111-117
-
-
Ouedraogo, R.1
Naslund, E.2
Kirchgessner, A.L.3
-
9
-
-
0042235091
-
The STC-1 cells express functional orexin-A receptors coupled to CCK release
-
Larsson KP, Akerman KE, Magga J, Uotila S, Kukkonen JP, Nasman J, Herzig KH 2003 The STC-1 cells express functional orexin-A receptors coupled to CCK release. Biochem Biophys Res Commun 309:209-216
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 209-216
-
-
Larsson, K.P.1
Akerman, K.E.2
Magga, J.3
Uotila, S.4
Kukkonen, J.P.5
Nasman, J.6
Herzig, K.H.7
-
11
-
-
0034612882
-
The orexin OX1 receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C
-
Lund PE, Shariatmadari R, Uustare A, Detheux M, Parmentier M, Kukkonen JP, Åkerman KEO 2000 The orexin OX1 receptor activates a novel Ca2+ influx pathway necessary for coupling to phospholipase C. J Biol Chem 275:30806-30812
-
(2000)
J Biol Chem
, vol.275
, pp. 30806-30812
-
-
Lund, P.E.1
Shariatmadari, R.2
Uustare, A.3
Detheux, M.4
Parmentier, M.5
Kukkonen, J.P.6
Åkerman, K.E.O.7
-
12
-
-
12544258350
-
Orexin-A-induced Ca2+ entry: Evidence for involvement of trpc channels and protein kinase C regulation
-
Larsson KP, Peltonen HM, Bart G, Louhivuori LM, Penttonen A, Antikainen M, Kukkonen JP, Åkerman KE 2005 Orexin-A-induced Ca2+ entry: evidence for involvement of trpc channels and protein kinase C regulation. J Biol Chem 280:1771-1781
-
(2005)
J Biol Chem
, vol.280
, pp. 1771-1781
-
-
Larsson, K.P.1
Peltonen, H.M.2
Bart, G.3
Louhivuori, L.M.4
Penttonen, A.5
Antikainen, M.6
Kukkonen, J.P.7
Åkerman, K.E.8
-
13
-
-
0034748701
-
Human pheochromocytomas express orexin receptor type 2 gene and display an in vitro secretory response to orexins a and B
-
Mazzocchi G, Malendowicz LK, Aragona F, Rebuffat P, Gottardo L, Nussdorfer GG 2001 Human pheochromocytomas express orexin receptor type 2 gene and display an in vitro secretory response to orexins A and B. J Clin Endocrinol Metab 86:4818-4821
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 4818-4821
-
-
Mazzocchi, G.1
Malendowicz, L.K.2
Aragona, F.3
Rebuffat, P.4
Gottardo, L.5
Nussdorfer, G.G.6
-
14
-
-
19444364013
-
Food deprivation differentially modulates orexin receptor expression and signalling in the rat hypothalamus and adrenal cortex
-
Karteris E, Machado RJ, Chen J, Zervou S, Hillhouse EW, Randeva HS 2005 Food deprivation differentially modulates orexin receptor expression and signalling in the rat hypothalamus and adrenal cortex. Am J Physiol Endocrinol Metab 288:E1089-E1100
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Karteris, E.1
Machado, R.J.2
Chen, J.3
Zervou, S.4
Hillhouse, E.W.5
Randeva, H.S.6
-
15
-
-
0032705117
-
Orexins stimulate corticosterone secretion of rat adrenocortical cells, through the activation of the adenylate cyclase-dependent signaling cascade
-
Malendowicz LK, Tortorella C, Nussdorfer GG 1999 Orexins stimulate corticosterone secretion of rat adrenocortical cells, through the activation of the adenylate cyclase-dependent signaling cascade. J Steroid Biochem Mol Biol 70:185-188
-
(1999)
J Steroid Biochem Mol Biol
, vol.70
, pp. 185-188
-
-
Malendowicz, L.K.1
Tortorella, C.2
Nussdorfer, G.G.3
-
16
-
-
14844332030
-
OX1 orexin receptors couple to adenylyl cyclase regulation via multiple mechanisms
-
Holmqvist T, Johansson L, Östman M, Ammoun S, Åkerman KE, Kukkonen JP 2005 OX1 orexin receptors couple to adenylyl cyclase regulation via multiple mechanisms. J Biol Chem 280:6570-6579
-
(2005)
J Biol Chem
, vol.280
, pp. 6570-6579
-
-
Holmqvist, T.1
Johansson, L.2
Östman, M.3
Ammoun, S.4
Åkerman, K.E.5
Kukkonen, J.P.6
-
17
-
-
0034110277
-
Contribution of receptor/G protein signaling to cell growth and transformation
-
Gudermann T, Grosse R, Schultz G 2000 Contribution of receptor/G protein signaling to cell growth and transformation. Naunyn Schmiedebergs Arch Pharmacol 361:345-362
-
(2000)
Naunyn Schmiedebergs Arch Pharmacol
, vol.361
, pp. 345-362
-
-
Gudermann, T.1
Grosse, R.2
Schultz, G.3
-
18
-
-
0034636685
-
Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors
-
Gutkind JS 2000 Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors. Sci STKE 40:RE1
-
(2000)
Sci STKE
, vol.40
-
-
Gutkind, J.S.1
-
19
-
-
0038606535
-
Hypersensitization of the orexin 1 receptor by the CB1 receptor: Evidence for cross-talk blocked by the specific CB1 antagonist, SR141716
-
Hilairet S, Bouaboula M, Carriere D, Le Fur G, Casellas P 2003 Hypersensitization of the orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716. J Biol Chem 278:23731-23737
-
(2003)
J Biol Chem
, vol.278
, pp. 23731-23737
-
-
Hilairet, S.1
Bouaboula, M.2
Carriere, D.3
Le Fur, G.4
Casellas, P.5
-
20
-
-
0037405843
-
Distinct recognition of OX1 and OX2 receptors by orexin peptides
-
Ammoun S, Holmqvist T, Shariatmadari R, Oonk HB, Detheux M, Parmentier M, Åkerman KE, Kukkonen JP 2003 Distinct recognition of OX1 and OX2 receptors by orexin peptides. J Pharmacol Exp Ther 305:507-514
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 507-514
-
-
Ammoun, S.1
Holmqvist, T.2
Shariatmadari, R.3
Oonk, H.B.4
Detheux, M.5
Parmentier, M.6
Åkerman, K.E.7
Kukkonen, J.P.8
-
21
-
-
0035800213
-
Orexin receptors couple to Ca2+ channels different from store-operated Ca2+ channels
-
Kukkonen JP, Åkerman KEO 2001 Orexin receptors couple to Ca2+ channels different from store-operated Ca2+ channels. Neuroreport 12:2017-2020
-
(2001)
Neuroreport
, vol.12
, pp. 2017-2020
-
-
Kukkonen, J.P.1
Åkerman, K.E.O.2
-
22
-
-
0026057140
-
Transmitter glutamate release from isolated nerve terminals: Evidence for biphasic release and triggering by localized Ca2+
-
McMahon HT, Nicholls DG 1991 Transmitter glutamate release from isolated nerve terminals: evidence for biphasic release and triggering by localized Ca2+. J Neurochem 56:86-94
-
(1991)
J Neurochem
, vol.56
, pp. 86-94
-
-
McMahon, H.T.1
Nicholls, D.G.2
-
23
-
-
0032608413
-
Endothelin-stimulated ERK activation in airway smooth-muscle cells requires calcium influx and Raf activation
-
Vichi P, Whelchel A, Knot H, Nelson M, Kolch W, Posada J 1999 Endothelin-stimulated ERK activation in airway smooth-muscle cells requires calcium influx and Raf activation. Am J Respir Cell Mol Biol 20:99-105
-
(1999)
Am J Respir Cell Mol Biol
, vol.20
, pp. 99-105
-
-
Vichi, P.1
Whelchel, A.2
Knot, H.3
Nelson, M.4
Kolch, W.5
Posada, J.6
-
24
-
-
0033569875
-
Calcium influx through L-type channels is required for selective activation of extracellular signal-regulated kinase by gonadotropin-releasing hormone
-
Mulvaney JM, Zhang T, Fewtrell C, Roberson MS 1999 Calcium influx through L-type channels is required for selective activation of extracellular signal-regulated kinase by gonadotropin-releasing hormone. J Biol Chem 274:29796-29804
-
(1999)
J Biol Chem
, vol.274
, pp. 29796-29804
-
-
Mulvaney, J.M.1
Zhang, T.2
Fewtrell, C.3
Roberson, M.S.4
-
25
-
-
0142153385
-
Molecular and cellular requirements for the regulation of adenylate cyclases by calcium
-
Cooper DM 2003 Molecular and cellular requirements for the regulation of adenylate cyclases by calcium. Biochem Soc Trans 31:912-915
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 912-915
-
-
Cooper, D.M.1
-
26
-
-
0034916496
-
2-Aminoethoxydiphenyl borate reveals heterogeneity in receptoractivated Ca(2+) discharge and store-operated Ca(2+) influx
-
Kukkonen JP, Lund PE, Åkerman KEO 2001 2-Aminoethoxydiphenyl borate reveals heterogeneity in receptoractivated Ca(2+) discharge and store-operated Ca(2+) influx. Cell Calcium 30:117-129
-
(2001)
Cell Calcium
, vol.30
, pp. 117-129
-
-
Kukkonen, J.P.1
Lund, P.E.2
Åkerman, K.E.O.3
-
27
-
-
0036329140
-
2-Aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release
-
Bootman MD, Collins TJ, Mackenzie L, Roderick HL, Berridge MJ, Peppiatt CM 2002 2-Aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release. FASEB J 16:1145-1150
-
(2002)
FASEB J
, vol.16
, pp. 1145-1150
-
-
Bootman, M.D.1
Collins, T.J.2
Mackenzie, L.3
Roderick, H.L.4
Berridge, M.J.5
Peppiatt, C.M.6
-
28
-
-
0027157640
-
Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976
-
Martiny-Baron G, Kazanietz MG, Mischak H, Blumberg PM, Kochs G, Hug H, Marme D, Schachtele C 1993 Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976. J Biol Chem 268:9194-9197
-
(1993)
J Biol Chem
, vol.268
, pp. 9194-9197
-
-
Martiny-Baron, G.1
Kazanietz, M.G.2
Mischak, H.3
Blumberg, P.M.4
Kochs, G.5
Hug, H.6
Marme, D.7
Schachtele, C.8
-
30
-
-
0036364408
-
A growing family of guanine nucleotide exchange factors is responsible for activation of Ras-family GTPases
-
Quilliam LA, Rebhun JF, Castro AF 2002 A growing family of guanine nucleotide exchange factors is responsible for activation of Ras-family GTPases. Prog Nucleic Acid Res Mol Biol 71:391-444
-
(2002)
Prog Nucleic Acid Res Mol Biol
, vol.71
, pp. 391-444
-
-
Quilliam, L.A.1
Rebhun, J.F.2
Castro, A.F.3
-
31
-
-
0034998678
-
Compartmentalization of Ras proteins
-
Prior IA, Hancock JF 2001 Compartmentalization of Ras proteins. J Cell Sci 114:1603-1608
-
(2001)
J Cell Sci
, vol.114
, pp. 1603-1608
-
-
Prior, I.A.1
Hancock, J.F.2
-
32
-
-
0031917171
-
Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo
-
Jones MK, Jackson JH 1998 Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo. J Biol Chem 273:1782-1787
-
(1998)
J Biol Chem
, vol.273
, pp. 1782-1787
-
-
Jones, M.K.1
Jackson, J.H.2
-
33
-
-
0032508517
-
Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase
-
Yan J, Roy S, Apolloni A, Lane A, Hancock JF 1998 Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase. J Biol Chem 273:24052-24056
-
(1998)
J Biol Chem
, vol.273
, pp. 24052-24056
-
-
Yan, J.1
Roy, S.2
Apolloni, A.3
Lane, A.4
Hancock, J.F.5
-
34
-
-
0037849951
-
Differences on the inhibitory specificities of H-Ras, K-Ras, and N-Ras (N17) dominant negative mutants are related to their membrane microlocalization
-
Matallanas D, Arozarena I, Berciano MT, Aaronson DS, Pellicer A, Lafarga M, Crespo P 2003 Differences on the inhibitory specificities of H-Ras, K-Ras, and N-Ras (N17) dominant negative mutants are related to their membrane microlocalization. J Biol Chem 278:4572-4581
-
(2003)
J Biol Chem
, vol.278
, pp. 4572-4581
-
-
Matallanas, D.1
Arozarena, I.2
Berciano, M.T.3
Aaronson, D.S.4
Pellicer, A.5
Lafarga, M.6
Crespo, P.7
-
36
-
-
0032563936
-
Regulation of protein kinase C ζ by PI 3-kinase and PDK-1
-
Chou MM, Hou W, Johnson J, Graham LK, Lee MH, Chen CS, Newton AC, Schaffhausen BS, Toker A 1998 Regulation of protein kinase C ζ by PI 3-kinase and PDK-1. Curr Biol 8:1069-1077
-
(1998)
Curr Biol
, vol.8
, pp. 1069-1077
-
-
Chou, M.M.1
Hou, W.2
Johnson, J.3
Graham, L.K.4
Lee, M.H.5
Chen, C.S.6
Newton, A.C.7
Schaffhausen, B.S.8
Toker, A.9
-
37
-
-
85006314494
-
A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK
-
Enserink JM, Christensen AE, de Rooij J, van Triest M, Schwede F, Genieser HG, Doskeland SO, Blank JL, Bos JL 2002 A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. Nat Cell Biol 4:901-906
-
(2002)
Nat Cell Biol
, vol.4
, pp. 901-906
-
-
Enserink, J.M.1
Christensen, A.E.2
De Rooij, J.3
Van Triest, M.4
Schwede, F.5
Genieser, H.G.6
Doskeland, S.O.7
Blank, J.L.8
Bos, J.L.9
-
38
-
-
0028360098
-
The ratPDE3/IVd phosphodiesterase gene codes for multiple proteins differentially activated by cAMP-dependent protein kinase
-
Sette C, Vicini E, Conti M 1994 The ratPDE3/IVd phosphodiesterase gene codes for multiple proteins differentially activated by cAMP-dependent protein kinase. J Biol Chem 269:18271-18274
-
(1994)
J Biol Chem
, vol.269
, pp. 18271-18274
-
-
Sette, C.1
Vicini, E.2
Conti, M.3
-
39
-
-
0026315434
-
Attenuation of cAMP-mediated responses in MA-10 Leydig tumor cells by genetic manipulation of a cAMP-phosphodiesterase
-
Swinnen JV, D'Souza B, Conti M, Ascoli M 1991 Attenuation of cAMP-mediated responses in MA-10 Leydig tumor cells by genetic manipulation of a cAMP-phosphodiesterase. J Biol Chem 266:14383-14389
-
(1991)
J Biol Chem
, vol.266
, pp. 14383-14389
-
-
Swinnen, J.V.1
D'Souza, B.2
Conti, M.3
Ascoli, M.4
-
40
-
-
0032584673
-
Subcellular localization of rolipram-sensitive, cAMP-specific phosphodiesterases. Differential targeting and activation of the splicing variants derived from the PDE4D gene
-
Jin SL, Bushnik T, Lan L, Conti M 1998 Subcellular localization of rolipram-sensitive, cAMP-specific phosphodiesterases. Differential targeting and activation of the splicing variants derived from the PDE4D gene. J Biol Chem 273:19672-19678
-
(1998)
J Biol Chem
, vol.273
, pp. 19672-19678
-
-
Jin, S.L.1
Bushnik, T.2
Lan, L.3
Conti, M.4
-
41
-
-
0031960313
-
A tool coming of age: Thapsigargin as an inhibitor of sarcoendoplasmic reticulum Ca(2+)-ATPases
-
Treiman M, Caspersen C, Christensen SB 1998 A tool coming of age: thapsigargin as an inhibitor of sarcoendoplasmic reticulum Ca(2+)-ATPases. Trends Pharmacol Sci 19:131-135
-
(1998)
Trends Pharmacol Sci
, vol.19
, pp. 131-135
-
-
Treiman, M.1
Caspersen, C.2
Christensen, S.B.3
-
42
-
-
0035827664
-
Mutual antagonism of calcium entry by capacitative and arachidonic acid-mediated calcium entry pathways
-
Luo D, Broad LM, Bird GS, Putney Jr JW 2001 Mutual antagonism of calcium entry by capacitative and arachidonic acid-mediated calcium entry pathways. J Biol Chem 276:20186-20189
-
(2001)
J Biol Chem
, vol.276
, pp. 20186-20189
-
-
Luo, D.1
Broad, L.M.2
Bird, G.S.3
Putney Jr., J.W.4
-
43
-
-
0035929573
-
Reciprocal regulation of capacitative and arachidonate-regulated noncapacitative Ca2+ entry pathways
-
Mignen O, Thompson JL, Shuttleworth TJ 2001 Reciprocal regulation of capacitative and arachidonate-regulated noncapacitative Ca2+ entry pathways. J Biol Chem 276:35676-35683
-
(2001)
J Biol Chem
, vol.276
, pp. 35676-35683
-
-
Mignen, O.1
Thompson, J.L.2
Shuttleworth, T.J.3
-
44
-
-
0033848878
-
Integrating the MAP kinase signal into the G1 phase cell cycle machinery
-
Roovers K, Assoian RK 2000 Integrating the MAP kinase signal into the G1 phase cell cycle machinery. Bioessays 22:818-826
-
(2000)
Bioessays
, vol.22
, pp. 818-826
-
-
Roovers, K.1
Assoian, R.K.2
-
45
-
-
0036709020
-
Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
-
Pouyssegur J, Volmat V, Lenormand P 2002 Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Biochem Pharmacol 64:755-763
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 755-763
-
-
Pouyssegur, J.1
Volmat, V.2
Lenormand, P.3
-
47
-
-
0037400510
-
Mechanisms of regulating the Raf kinase family
-
Chong H, Vikis HG, Guan KL 2003 Mechanisms of regulating the Raf kinase family. Cell Signal 15:463-469
-
(2003)
Cell Signal
, vol.15
, pp. 463-469
-
-
Chong, H.1
Vikis, H.G.2
Guan, K.L.3
-
48
-
-
0036893642
-
Orexin-A augments voltage-gated Ca(2+) currents and synergistically increases growth hormone (GH) secretion with GH-releasing hormone in primary cultured ovine somatotropes
-
Xu R, Wang Q, Yan M, Hernandez M, Gong C, Boon WC, Murata Y, Ueta Y, Chen C 2002 Orexin-A augments voltage-gated Ca(2+) currents and synergistically increases growth hormone (GH) secretion with GH-releasing hormone in primary cultured ovine somatotropes. Endocrinology 143:4609-4619
-
(2002)
Endocrinology
, vol.143
, pp. 4609-4619
-
-
Xu, R.1
Wang, Q.2
Yan, M.3
Hernandez, M.4
Gong, C.5
Boon, W.C.6
Murata, Y.7
Ueta, Y.8
Chen, C.9
-
49
-
-
12144284564
-
Pharmacological properties of GABAA receptors in rat hypothalamic neurons expressing the ε-subunit
-
Sergeeva OA, Andreeva N, Garret M, Scherer A, Haas HL 2005 Pharmacological properties of GABAA receptors in rat hypothalamic neurons expressing the ε-subunit. J Neurosci 25:88-95
-
(2005)
J Neurosci
, vol.25
, pp. 88-95
-
-
Sergeeva, O.A.1
Andreeva, N.2
Garret, M.3
Scherer, A.4
Haas, H.L.5
-
50
-
-
0035939299
-
1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor
-
Porter RA, Chan WN, Coulton S, Johns A, Hadley MS, Widdowson K, Jerman JC, Brough SJ, Coldwell M, Smart D, Jewitt F, Jeffrey P, Austin N 2001 1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor. Bioorg Med Chem Lett 11:1907-1910
-
(2001)
Bioorg Med Chem Lett
, vol.11
, pp. 1907-1910
-
-
Porter, R.A.1
Chan, W.N.2
Coulton, S.3
Johns, A.4
Hadley, M.S.5
Widdowson, K.6
Jerman, J.C.7
Brough, S.J.8
Coldwell, M.9
Smart, D.10
Jewitt, F.11
Jeffrey, P.12
Austin, N.13
-
51
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF, Ahn NG 1994 Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265:966-970
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
Candia, J.M.4
Rong, S.5
Fukasawa, K.6
Vande Woude, G.F.7
Ahn, N.G.8
-
52
-
-
0032510323
-
Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells
-
Stauffer TP, Ahn S, Meyer T 1998 Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells. Curr Biol 8:343-346
-
(1998)
Curr Biol
, vol.8
, pp. 343-346
-
-
Stauffer, T.P.1
Ahn, S.2
Meyer, T.3
-
53
-
-
0037099313
-
PKC ε controls the traffic of β1 integrins in motile cells
-
Ivaska J, Whelan RD, Watson R, Parker PJ 2002 PKC ε controls the traffic of β1 integrins in motile cells. EMBO J 21:3608-3619
-
(2002)
EMBO J
, vol.21
, pp. 3608-3619
-
-
Ivaska, J.1
Whelan, R.D.2
Watson, R.3
Parker, P.J.4
-
54
-
-
0033946740
-
Phosphorylation of the PTEN tail regulates protein stability and function
-
Vazquez F, Ramaswamy S, Nakamura N, Sellers WR 2000 Phosphorylation of the PTEN tail regulates protein stability and function. Mol Cell Biol 20:5010-5018
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5010-5018
-
-
Vazquez, F.1
Ramaswamy, S.2
Nakamura, N.3
Sellers, W.R.4
-
55
-
-
0030911052
-
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
-
Rodriguez-Viciana P, Warne PH, Khwaja A, Marte BM, Pappin D, Das P, Waterfield MD, Ridley A, Downward J 1997 Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell 89:457-467
-
(1997)
Cell
, vol.89
, pp. 457-467
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Khwaja, A.3
Marte, B.M.4
Pappin, D.5
Das, P.6
Waterfield, M.D.7
Ridley, A.8
Downward, J.9
-
56
-
-
0029068339
-
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
-
Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JS, Sukhatme VP 1995 Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature 375:577-581
-
(1995)
Nature
, vol.375
, pp. 577-581
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Zhou, X.M.3
Foster, D.4
Brugge, J.S.5
Sukhatme, V.P.6
-
57
-
-
0025881470
-
Cloning of a complementary DNA for a proteintyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src
-
Nada S, Okada M, MacAuley A, Cooper JA, Nakagawa H 1991 Cloning of a complementary DNA for a proteintyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src. Nature 351:69-72
-
(1991)
Nature
, vol.351
, pp. 69-72
-
-
Nada, S.1
Okada, M.2
MacAuley, A.3
Cooper, J.A.4
Nakagawa, H.5
-
58
-
-
0026754369
-
Activation of the MAP kinase pathway by the protein kinase raf
-
Howe LR, Leevers SJ, Gomez N, Nakielny S, Cohen P, Marshall CJ 1992 Activation of the MAP kinase pathway by the protein kinase raf. Cell 71:335-342
-
(1992)
Cell
, vol.71
, pp. 335-342
-
-
Howe, L.R.1
Leevers, S.J.2
Gomez, N.3
Nakielny, S.4
Cohen, P.5
Marshall, C.J.6
-
59
-
-
0030022174
-
Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation
-
Urano T, Emkey R, Feig LA 1996 Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation. EMBO J 15:810-816
-
(1996)
EMBO J
, vol.15
, pp. 810-816
-
-
Urano, T.1
Emkey, R.2
Feig, L.A.3
-
60
-
-
21744442922
-
Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue
-
Richter W, Jin SL, Conti M 2005 Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue. Biochem J 388:803-811
-
(2005)
Biochem J
, vol.388
, pp. 803-811
-
-
Richter, W.1
Jin, S.L.2
Conti, M.3
-
61
-
-
0025604215
-
Computer-assisted quantification and image processing of whole-body autoradiograms
-
d'Argy R, Sperber GO, Larsson BS, Ullberg S 1990 Computer-assisted quantification and image processing of whole-body autoradiograms. J Pharmacol Methods 24:165-181
-
(1990)
J Pharmacol Methods
, vol.24
, pp. 165-181
-
-
D'Argy, R.1
Sperber, G.O.2
Larsson, B.S.3
Ullberg, S.4
-
62
-
-
0035070287
-
Agonist trafficking of G(i/o)-mediated α(2A)-adrenoceptor responses in HEL 92.1.7 cells
-
Kukkonen JP, Jansson CC, Åkerman KEO 2001 Agonist trafficking of G(i/o)-mediated α(2A)-adrenoceptor responses in HEL 92.1.7 cells. Br J Pharmacol 132:1477-1484
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1477-1484
-
-
Kukkonen, J.P.1
Jansson, C.C.2
Åkerman, K.E.O.3
-
63
-
-
0020595443
-
Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides
-
Berridge MJ, Dawson RM, Downes CP, Heslop JP, Irvine RF 1983 Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides. Biochem J 212:473-482
-
(1983)
Biochem J
, vol.212
, pp. 473-482
-
-
Berridge, M.J.1
Dawson, R.M.2
Downes, C.P.3
Heslop, J.P.4
Irvine, R.F.5
-
64
-
-
4644257566
-
The phospholipase C activator m-3M3FBS mobilises Ca2+ independently of phospholipase C activation
-
Krjukova J, Holmqvist T, Danis AS, Åkerman KEO, Kukkonen JP 2004 The phospholipase C activator m-3M3FBS mobilises Ca2+ independently of phospholipase C activation. Br J Pharmacol 143:3-7
-
(2004)
Br J Pharmacol
, vol.143
, pp. 3-7
-
-
Krjukova, J.1
Holmqvist, T.2
Danis, A.S.3
Åkerman, K.E.O.4
Kukkonen, J.P.5
-
65
-
-
33644856430
-
G-protein-coupled OX1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress- activated protein kinase
-
10 Nov 10.1074/jbc.M508603200
-
Ammoun S, Lindholm D, Wootz H, Åkerman KE, Kukkonen JP 10 Nov 2005 G-protein-coupled OX1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress- activated protein kinase. J Biol Chem 10.1074/jbc.M508603200
-
(2005)
J Biol Chem
-
-
Ammoun, S.1
Lindholm, D.2
Wootz, H.3
Åkerman, K.E.4
Kukkonen, J.P.5
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