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Volumn 149, Issue 8, 2008, Pages 4106-4115

Orexins stimulate steroidogenic acute regulatory protein expression through multiple signaling pathways in human adrenal H295R cells

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 14; OREXIN; OREXIN A; OREXIN B; REGULATOR PROTEIN; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

EID: 47949132482     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-1739     Document Type: Article
Times cited : (36)

References (46)
  • 3
    • 0141920775 scopus 로고    scopus 로고
    • Orexin receptors and G-protein coupling: Evidence for another "promiscuous" seven transmembrane domain receptor
    • Karteris E, Randeva HS 2003 Orexin receptors and G-protein coupling: evidence for another "promiscuous" seven transmembrane domain receptor. J Pharmacol Sci 93:126-128
    • (2003) J Pharmacol Sci , vol.93 , pp. 126-128
    • Karteris, E.1    Randeva, H.S.2
  • 6
    • 0034750656 scopus 로고    scopus 로고
    • Expression of orexin-A and functional orexin type 2 receptors in the human adult adrenals: Implications for adrenal function and energy homeostasis
    • Randeva HS, Karteris E, Grammatopoulos D, Hillhouse EW 2001 Expression of orexin-A and functional orexin type 2 receptors in the human adult adrenals: implications for adrenal function and energy homeostasis. J Clin Endocrinol Metab 86:4808-4813
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4808-4813
    • Randeva, H.S.1    Karteris, E.2    Grammatopoulos, D.3    Hillhouse, E.W.4
  • 8
    • 3242752886 scopus 로고    scopus 로고
    • Glucocorticoid-dependency of increased adiposity in a model of hypothalamic obesity
    • Perello M, Moreno G, Gaillard RC, Spinedi E 2004 Glucocorticoid-dependency of increased adiposity in a model of hypothalamic obesity. Neuro Endocrinol Lett 25:119-126
    • (2004) Neuro Endocrinol Lett , vol.25 , pp. 119-126
    • Perello, M.1    Moreno, G.2    Gaillard, R.C.3    Spinedi, E.4
  • 10
    • 21244465999 scopus 로고    scopus 로고
    • Preproorexin and orexin receptors are expressed in cortisol-secreting adrenocortical adenomas, and orexins stimulate in vitro cortisol secretion and growth of tumor cells
    • Spinazzi R, Rucinski M, Neri G, Malendowicz LK, Nussdorfer GG 2005 Preproorexin and orexin receptors are expressed in cortisol-secreting adrenocortical adenomas, and orexins stimulate in vitro cortisol secretion and growth of tumor cells. J Clin Endocrinol Metab 90:3544-3549
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3544-3549
    • Spinazzi, R.1    Rucinski, M.2    Neri, G.3    Malendowicz, L.K.4    Nussdorfer, G.G.5
  • 13
    • 34249787877 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter
    • Miller WL 2007 Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter. Biochim Biophys Acta 1771:663-676
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 663-676
    • Miller, W.L.1
  • 14
    • 0344084434 scopus 로고    scopus 로고
    • Inborn errors of adrenal steroidogenesis
    • New MI 2003 Inborn errors of adrenal steroidogenesis. Mol Cell Endocrinol 211:75-83
    • (2003) Mol Cell Endocrinol , vol.211 , pp. 75-83
    • New, M.I.1
  • 15
    • 0028104418 scopus 로고
    • The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)
    • Clark BJ, Wells J, King SR, Stocco DM 1994 The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). J Biol Chem 269:28314-28322
    • (1994) J Biol Chem , vol.269 , pp. 28314-28322
    • Clark, B.J.1    Wells, J.2    King, S.R.3    Stocco, D.M.4
  • 16
    • 0034899563 scopus 로고    scopus 로고
    • Tracking the role of a star in the sky of the new millennium
    • Stocco DM 2001 Tracking the role of a star in the sky of the new millennium. Mol Endocrinol 15:1245-1254
    • (2001) Mol Endocrinol , vol.15 , pp. 1245-1254
    • Stocco, D.M.1
  • 18
    • 0034457234 scopus 로고    scopus 로고
    • Regulation by adrenocorticotropin (ACTH), angiotensin II, transforming growth factor-β, and insulin-like growth factor I of bovine adrenal cell steroidogenic capacity and expression of ACTH receptor, steroidogenic acute regulatory protein, cytochrome P450c17, and 3β-hydroxysteroid dehydrogenase
    • Le Roy C, Li JY, Stocco DM, Langlois D, Saez JM 2000 Regulation by adrenocorticotropin (ACTH), angiotensin II, transforming growth factor-β, and insulin-like growth factor I of bovine adrenal cell steroidogenic capacity and expression of ACTH receptor, steroidogenic acute regulatory protein, cytochrome P450c17, and 3β-hydroxysteroid dehydrogenase. Endocrinology 141:1599-1607
    • (2000) Endocrinology , vol.141 , pp. 1599-1607
    • Le Roy, C.1    Li, J.Y.2    Stocco, D.M.3    Langlois, D.4    Saez, J.M.5
  • 20
    • 27644505023 scopus 로고    scopus 로고
    • Multiple signaling pathways regulating steroidogenesis and steroidogenic acute regulatory protein expression: More complicated than we thought
    • Stocco DM, Wang X, Jo Y, Manna PR 2005 Multiple signaling pathways regulating steroidogenesis and steroidogenic acute regulatory protein expression: more complicated than we thought. Mol Endocrinol 19:2647-2659
    • (2005) Mol Endocrinol , vol.19 , pp. 2647-2659
    • Stocco, D.M.1    Wang, X.2    Jo, Y.3    Manna, P.R.4
  • 21
    • 0028287061 scopus 로고
    • The NCI-H295 cell line: A pluripotent model for human adrenocortical studies
    • Rainey WE, Bird IM, Mason JI 1994 The NCI-H295 cell line: a pluripotent model for human adrenocortical studies. Mol Cell Endocrinol 100:45-50
    • (1994) Mol Cell Endocrinol , vol.100 , pp. 45-50
    • Rainey, W.E.1    Bird, I.M.2    Mason, J.I.3
  • 22
    • 0034918190 scopus 로고    scopus 로고
    • Tissue-specific expression pattern of estrogen receptors (ER): Quantification of ERα and ERβ mRNA with real-time RT-PCR
    • Pfaffl MW, Lange IG, Daxenberger A, Meyer HH 2001 Tissue-specific expression pattern of estrogen receptors (ER): quantification of ERα and ERβ mRNA with real-time RT-PCR. APMIS 109:345-355
    • (2001) APMIS , vol.109 , pp. 345-355
    • Pfaffl, M.W.1    Lange, I.G.2    Daxenberger, A.3    Meyer, H.H.4
  • 23
    • 15444380459 scopus 로고    scopus 로고
    • Regulation of the steroidogenic acute regulatory protein expression: Functional and physiological consequences
    • Manna PR, Stocco DM 2005 Regulation of the steroidogenic acute regulatory protein expression: functional and physiological consequences. Curr Drug Targets Immune Endocr Metabol Disord 5:93-108
    • (2005) Curr Drug Targets Immune Endocr Metabol Disord , vol.5 , pp. 93-108
    • Manna, P.R.1    Stocco, D.M.2
  • 24
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts PJ, Der CJ 2007 Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26:3291-3310
    • (2007) Oncogene , vol.26 , pp. 3291-3310
    • Roberts, P.J.1    CJ, D.2
  • 26
    • 0032705117 scopus 로고    scopus 로고
    • Orexins stimulate corticosterone secretion of rat adrenocortical cells, through the activation of the adenylate cyclase-dependent signaling cascade
    • Malendowicz LK, Tortorella C, Nussdorfer GG 1999 Orexins stimulate corticosterone secretion of rat adrenocortical cells, through the activation of the adenylate cyclase-dependent signaling cascade. J Steroid Biochem Mol Biol 70:185-188
    • (1999) J Steroid Biochem Mol Biol , vol.70 , pp. 185-188
    • Malendowicz, L.K.1    Tortorella, C.2    Nussdorfer, G.G.3
  • 27
    • 0035097290 scopus 로고    scopus 로고
    • Orexin A stimulates cortisol secretion from human adrenocortical cells through activation of the adenylate cyclase-dependent signaling cascade
    • Mazzocchi G, Malendowicz LK, Gottardo L, Aragona F, Nussdorfer GG 2001 Orexin A stimulates cortisol secretion from human adrenocortical cells through activation of the adenylate cyclase-dependent signaling cascade. J Clin Endocrinol Metab 86:778-782
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 778-782
    • Mazzocchi, G.1    Malendowicz, L.K.2    Gottardo, L.3    Aragona, F.4    Nussdorfer, G.G.5
  • 28
    • 32144443121 scopus 로고    scopus 로고
    • Agonist potency differentiates G protein activation and Ca2+ signalling by the orexin receptor type 1
    • Magga J, Bart G, Oker-Blom C, Kukkonen JP, Akerman KE, Nasman J 2006 Agonist potency differentiates G protein activation and Ca2+ signalling by the orexin receptor type 1. Biochem Pharmacol 71:827-836
    • (2006) Biochem Pharmacol , vol.71 , pp. 827-836
    • Magga, J.1    Bart, G.2    Oker-Blom, C.3    Kukkonen, J.P.4    Akerman, K.E.5    Nasman, J.6
  • 29
    • 0023868553 scopus 로고
    • Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH
    • Simpson ER, Waterman MR 1988 Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH. Annu Rev Physiol 50:427-440
    • (1988) Annu Rev Physiol , vol.50 , pp. 427-440
    • Simpson, E.R.1    Waterman, M.R.2
  • 31
    • 0031731177 scopus 로고    scopus 로고
    • Early steps in androgen biosynthesis: From cholesterol to DHEA
    • Miller WL 1998 Early steps in androgen biosynthesis: from cholesterol to DHEA. Baillieres Clin Endocrinol Metab 12:67-81
    • (1998) Baillieres Clin Endocrinol Metab , vol.12 , pp. 67-81
    • Miller, W.L.1
  • 32
    • 0030040802 scopus 로고    scopus 로고
    • Role of the steroidogenic acute regulatory protein (StAR) in steroidogenesis
    • Stocco DM, Clark BJ 1996 Role of the steroidogenic acute regulatory protein (StAR) in steroidogenesis. Biochem Pharmacol 51:197-205
    • (1996) Biochem Pharmacol , vol.51 , pp. 197-205
    • Stocco, D.M.1    Clark, B.J.2
  • 33
    • 0038606535 scopus 로고    scopus 로고
    • Hypersensitization of the Orexin 1 receptor by the CB1 receptor: Evidence for cross-talk blocked by the specific CB1 antagonist, SR141716
    • Hilairet S, Bouaboula M, Carriere D, Le Fur G, Casellas P 2003 Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716. J Biol Chem 278:23731-23737
    • (2003) J Biol Chem , vol.278 , pp. 23731-23737
    • Hilairet, S.1    Bouaboula, M.2    Carriere, D.3    Le Fur, G.4    Casellas, P.5
  • 34
    • 33747880805 scopus 로고    scopus 로고
    • cAMP-independent signaling regulates steroidogenesis in mouse Leydig cells in the absence of StAR phosphorylation
    • Manna PR, Chandrala SP, Jo Y, Stocco DM 2006 cAMP-independent signaling regulates steroidogenesis in mouse Leydig cells in the absence of StAR phosphorylation. J Mol Endocrinol 37:81-95
    • (2006) J Mol Endocrinol , vol.37 , pp. 81-95
    • Manna, P.R.1    Chandrala, S.P.2    Jo, Y.3    Stocco, D.M.4
  • 36
    • 0029621116 scopus 로고
    • The steroidogenic acute regulatory protein is induced by angiotensin II and K+ in H295R adrenocortical cells
    • Clark BJ, Pezzi V, Stocco DM, Rainey WE 1995 The steroidogenic acute regulatory protein is induced by angiotensin II and K+ in H295R adrenocortical cells. Mol Cell Endocrinol 115:215-219
    • (1995) Mol Cell Endocrinol , vol.115 , pp. 215-219
    • Clark, B.J.1    Pezzi, V.2    Stocco, D.M.3    Rainey, W.E.4
  • 39
    • 4444287241 scopus 로고    scopus 로고
    • Phosphorylation and function of the hamster adrenal steroidogenic acute regulatory protein (StAR)
    • Fleury A, Mathieu AP, Ducharme L, Hales DB, LeHoux JG 2004 Phosphorylation and function of the hamster adrenal steroidogenic acute regulatory protein (StAR). J Steroid Biochem Mol Biol 91:259-271
    • (2004) J Steroid Biochem Mol Biol , vol.91 , pp. 259-271
    • Fleury, A.1    Mathieu, A.P.2    Ducharme, L.3    Hales, D.B.4    LeHoux, J.G.5
  • 40
    • 4644293240 scopus 로고    scopus 로고
    • Extracellular signalregulated kinases are involved in the acute activation of steroidogenesis in immature rat Leydig cells by human chorionic gonadotropin
    • Martinelle N, Holst M, Soder O, Svechnikov K 2004 Extracellular signalregulated kinases are involved in the acute activation of steroidogenesis in immature rat Leydig cells by human chorionic gonadotropin. Endocrinology 145:4629-4634
    • (2004) Endocrinology , vol.145 , pp. 4629-4634
    • Martinelle, N.1    Holst, M.2    Soder, O.3    Svechnikov, K.4
  • 41
    • 34748864760 scopus 로고    scopus 로고
    • Human adipocytes induce an ERK1/2 MAP kinases-mediated upregulation of steroidogenic acute regulatory protein (StAR) and an angiotensin II-sensitization in human adrenocortical cells
    • Krug AW, Vleugels K, Schinner S, Lamounier-Zepter V, Ziegler CG, Bornstein SR, Ehrhart-Bornstein M 2007 Human adipocytes induce an ERK1/2 MAP kinases-mediated upregulation of steroidogenic acute regulatory protein (StAR) and an angiotensin II-sensitization in human adrenocortical cells. Int J Obes (Lond) 31:1605-1616
    • (2007) Int J Obes (Lond) , vol.31 , pp. 1605-1616
    • Krug, A.W.1    Vleugels, K.2    Schinner, S.3    Lamounier-Zepter, V.4    Ziegler, C.G.5    Bornstein, S.R.6    Ehrhart-Bornstein, M.7
  • 42
    • 3042854240 scopus 로고    scopus 로고
    • Reciprocal influences between the signalling pathways regulating proliferation and steroidogenesis in adrenal glomerulosa cells
    • Foster RH 2004 Reciprocal influences between the signalling pathways regulating proliferation and steroidogenesis in adrenal glomerulosa cells. J Mol Endocrinol 32:893-902
    • (2004) J Mol Endocrinol , vol.32 , pp. 893-902
    • Foster, R.H.1
  • 43
    • 33847053928 scopus 로고    scopus 로고
    • Role of MAPKs in angiotensin II-induced steroidogenesis in rat glomerulosa cells
    • Otis M, Gallo-Payet N 2007 Role of MAPKs in angiotensin II-induced steroidogenesis in rat glomerulosa cells. Mol Cell Endocrinol 265-266:126-130
    • (2007) Mol Cell Endocrinol , vol.265-266 , pp. 126-130
    • Otis, M.1    Gallo-Payet, N.2
  • 44
    • 0141500061 scopus 로고    scopus 로고
    • Interleukin-1α stimulates steroidogenic acute regulatory protein expression via p38 MAP kinase in immature rat Leydig cells
    • Svechnikov K, Stocco DM, Soder O 2003 Interleukin-1α stimulates steroidogenic acute regulatory protein expression via p38 MAP kinase in immature rat Leydig cells. J Mol Endocrinol 30:59-67
    • (2003) J Mol Endocrinol , vol.30 , pp. 59-67
    • Svechnikov, K.1    Stocco, D.M.2    Soder, O.3
  • 45
    • 31444442754 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin-like growth factor-I mediated regulation of the steroidogenic acute regulatory protein in mouse Leydig cells
    • Manna PR, Chandrala SP, King SR, Jo Y, Counis R, Huhtaniemi IT, Stocco DM 2006 Molecular mechanisms of insulin-like growth factor-I mediated regulation of the steroidogenic acute regulatory protein in mouse Leydig cells. Mol Endocrinol 20:362-378
    • (2006) Mol Endocrinol , vol.20 , pp. 362-378
    • Manna, P.R.1    Chandrala, S.P.2    King, S.R.3    Jo, Y.4    Counis, R.5    Huhtaniemi, I.T.6    Stocco, D.M.7
  • 46
    • 17244373563 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases (ERK) 1, 2 are required for luteinizing hormone (LH)-induced steroidogenesis in primary Leydig cells and control steroidogenic acute regulatory (StAR) expression
    • Martinat N, Crepieux P, Reiter E, Guillou F 2005 Extracellular signal-regulated kinases (ERK) 1, 2 are required for luteinizing hormone (LH)-induced steroidogenesis in primary Leydig cells and control steroidogenic acute regulatory (StAR) expression. Reprod Nutr Dev 45:101-108
    • (2005) Reprod Nutr Dev , vol.45 , pp. 101-108
    • Martinat, N.1    Crepieux, P.2    Reiter, E.3    Guillou, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.