Adrenal expression of orexin receptor subtypes is differentially regulated in experimental streptozotocin induced type-1 diabetes

Peptides

Volumn 27, Issue 11, 2006, Pages 2764-2769

  Jöhren, Olaf ^a   Gremmels, Julia A F ^a   Qadri, Fatimunnisa ^a   Dendorfer, Andreas ^a   Dominiak, Peter ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; LEPTIN; MESSENGER RNA; OREXIN 1 RECEPTOR; OREXIN 2 RECEPTOR; RECEPTOR SUBTYPE; STREPTOZOCIN;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; HYPOTHALAMUS; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADRENAL GLANDS; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, TYPE 1; HYPOTHALAMUS; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEPTIN; MALE; NEUROPEPTIDES; PITUITARY GLAND; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; RNA, MESSENGER; STREPTOZOCIN;

EID: 33750042604     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2006.05.008     Document Type: Article

References (42)

1. Arihara Z., Takahashi K., Murakami O., Totsune K., Sone M., Satoh F., et al. Immunoreactive orexin-A in human plasma. Peptides 22 (2001) 139-142
2. Beuckmann C.T., and Yanagisawa M. Orexins: from neuropeptides to energy homeostasis and sleep/wake regulation. J Mol Med 80 (2002) 329-342
3. Cai X.J., Evans M.L., Lister C.A., Leslie R.A., Arch J.R., Wilson S., et al. Hypoglycemia activates orexin neurons and selectively increases hypothalamic orexin-B levels: responses inhibited by feeding and possibly mediated by the nucleus of the solitary tract. Diabetes 50 (2001) 105-112
4. Cai X.J., Lister C.A., Buckingham R.E., Pickavance L., Wilding J., Arch J.R., et al. Down-regulation of orexin gene expression by severe obesity in the rats: studies in Zucker fatty and zucker diabetic fatty rats and effects of rosiglitazone. Brain Res Mol Brain Res 77 (2000) 131-137
5. Chemelli R.M., Willie J.T., Sinton C.M., Elmquist J.K., Scammell T., Lee C., et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 98 (1999) 437-451
6. Cutler D.J., Morris R., Sheridhar V., Wattam T.A., Holmes S., Patel S., et al. Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord. Peptides 20 (1999) 1455-1470
7. Date Y., Ueta Y., Yamashita H., Yamaguchi H., Matsukura S., Kangawa K., et al. Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proc Natl Acad Sci USA 96 (1999) 748-753
8. de Lecea L., Kilduff T.S., Peyron C., Gao X., Foye P.E., Danielson P.E., et al. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci USA 95 (1998) 322-327
9. Hagan J.J., Leslie R.A., Patel S., Evans M.L., Wattam T.A., Holmes S., et al. Orexin A activates locus coeruleus cell firing and increases arousal in the rat. Proc Natl Acad Sci USA 96 (1999) 10911-10916
10. Ida T., Nakahara K., Murakami T., Hanada R., Nakazato M., and Murakami N. Possible involvement of orexin in the stress reaction in rats. Biochem Biophys Res Commun 270 (2000) 318-323
11. Jöhren O., Brüggemann N., Dendorfer A., and Dominiak P. Gonadal steroids differentially regulate the messenger ribonucleic acid expression of pituitary orexin type 1 receptors and adrenal orexin type 2 receptors. Endocrinology 144 (2003) 1219-1225
12. Jöhren O., Brüggemann N., and Dominiak P. Orexins (hypocretins) and adrenal function. Horm Metab Res 36 (2004) 370-375
13. Jöhren O., Golsch C., Dendorfer A., Qadri F., Häuser W., and Dominiak P. Differential expression of AT1 receptors in the pituitary and adrenal gland of SHR and WKY. Hypertension 41 (2003) 984-990
14. Jöhren O., Neidert S.J., Kummer M., Dendorfer A., and Dominiak P. Prepro-orexin and orexin receptor mRNAs are differentially expressed in peripheral tissues of male and female rats. Endocrinology 142 (2001) 3324-3331
15. Jöhren O., Neidert S.J., Kummer M., and Dominiak P. Sexually dimorphic expression of prepro-orexin mRNA in the rat hypothalamus. Peptides 23 (2002) 1177-1180
16. Karteris E., Machado R.J., Chen J., Zervou S., Hillhouse E.W., and Randeva H.S. Food deprivation differentially modulates orexin receptor expression and signaling in rat hypothalamus and adrenal cortex. Am J Physiol Endocrinol Metab 288 (2005) E1089-E1100
17. Kastin A.J., and Akerstrom V. Orexin A but not orexin B rapidly enters brain from blood by simple diffusion. J Pharmacol Exp Ther 289 (1999) 219-223
18. Kirchgessner A.L., and Liu M. Orexin synthesis and response in the gut. Neuron 24 (1999) 941-951
19. Lin L., Faraco J., Li R., Kadotani H., Rogers W., Lin X., et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexisn) receptor 2 gene. Cell 98 (1999) 365-376
20. Marcus J.N., Aschkenasi C.J., Lee C.E., Chemelli R.M., Saper C.B., Yanagisawa M., et al. Differential expression of orexin receptors 1 and 2 in the rat brain. J Comp Neurol 435 (2001) 6-25
21. Mazzocchi G., Malendowicz L.K., Gottardo L., Aragona F., and Nussdorfer G.G. Orexin A stimulates cortisol secretion from human adrenocortical cells through activation of the adenylate cyclase-dependent signaling cascade. J Clin Endocrinol Metab 86 (2001) 778-782
22. Nishino S., Ripley B., Overeem S., Lammers G.J., and Mignot E. Hypocretin (orexin) deficiency in human narcolepsy. Lancet 355 (2000) 39-40
23. Ouedraogo R., Naslund E., and Kirchgessner A.L. Glucose regulates the release of orexin-a from the endocrine pancreas. Diabetes 52 (2003) 111-117
24. Peyron C., Faraco J., Rogers W., Ripley B., Overeem S., Charnay Y., et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 6 (2000) 991-997
25. Peyron C., Tighe D.K., van den Pol A.N., de Lecea L., Heller H.C., Sutcliffe J.G., et al. Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci 18 (1998) 9996-10015
26. Pu S., Jain M.R., Kalra P.S., and Kalra S.P. Orexins, a novel family of hypothalamic neuropeptides, modulate pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner. Regul Pept 78 (1998) 133-136
27. Rakieten N., Rakieten M.L., and Nadkarni M.V. Studies on the diabetogenic action of streptozotocin (NSC-37917). Cancer Chemother Rep 29 (1963) 91-98
28. Randeva H.S., Karteris E., Grammatopoulos D., and Hillhouse E.W. Expression of orexin-A and functional orexin type 2 receptors in the human adult adrenals: implications for adrenal function and energy homeostasis. J Clin Endocrinol Metab 86 (2001) 4808-4813
29. Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanaka H., et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92 (1998) 573-585
30. Samson W.K., Gosnell B., Chang J.K., Resch Z.T., and Murphy T.C. Cardiovascular regulatory actions of the hypocretins in brain. Brain Res 831 (1999) 248-253
31. Samson W.K., and Taylor M.M. Hypocretin/orexin suppresses corticotroph responsiveness in vitro. Am J Physiol Regul Integr Comp Physiol 281 (2001) R1140-R1145
32. Samson W.K., Taylor M.M., Follwell M., and Ferguson A.V. Orexin actions in hypothalamic paraventricular nucleus: physiological consequences and cellular correlates. Regul Pept 104 (2002) 97-103
33. Shirasaka T., Nakazato M., Matsukura S., Takasaki M., and Kannan H. Sympathetic and cardiovascular actions of orexins in conscious rats. Am J Physiol 277 (1999) R1780-R1785
34. Siegel J.M. The neurotransmitters of sleep. J Clin Psychiatry 65 Suppl 16 (2004) 4-7
35. Sugimoto T., Nagake Y., Sugimoto S., Akagi S., Ichikawa H., Nakamura Y., et al. Plasma orexin concentrations in patients on hemodialysis. Nephron 90 (2002) 379-383
36. Swart I., Overton J.M., and Houpt T.A. The effect of food deprivation and experimental diabetes on orexin and NPY mRNA levels. Peptides 22 (2001) 2175-2179
37. Thannickal T.C., Moore R.Y., Nienhuis R., Ramanathan L., Gulyani S., Aldrich M., et al. Reduced number of hypocretin neurons in human narcolepsy. Neuron 27 (2000) 469-474
38. Tritos N.A., Mastaitis J.W., Kokkotou E., and Maratos-Flier E. Characterization of melanin concentrating hormone and preproorexin expression in the murine hypothalamus. Brain Res 895 (2001) 160-166
39. Tsuneki H., Sugihara Y., Honda R., Wada T., Sasaoka T., and Kimura I. Reduction of blood glucose level by orexins in fasting normal and streptozotocin-diabetic mice. Eur J Pharmacol 448 (2002) 245-252
40. van den Pol A.N. Hypothalamic hypocretin (orexin): robust innervation of the spinal cord. J Neurosci 19 (1999) 3171-3182
41. Yamamoto Y., Ueta Y., Yamashita H., Asayama K., and Shirahata A. Expressions of the prepro-orexin and orexin type 2 receptor genes in obese rat. Peptides 23 (2002) 1689-1696
42. Yamanaka A., Beuckmann C.T., Willie J.T., Hara J., Tsujino N., Mieda M., et al. Hypothalamic orexin neurons regulate arousal according to energy balance in mice. Neuron 38 (2003) 701-713