-
1
-
-
13544270249
-
Profiling early head and neck cancer
-
DOI 10.1038/nrc1548
-
Hunter, K.D., Parkinson, E.K., and Harrison, P.R. 2005. Profiling early head and neck cancer. Nat. Rev. Cancer. 5:127-135. (Pubitemid 40220338)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.2
, pp. 127-135
-
-
Hunter, K.D.1
Parkinson, E.K.2
Harrison, P.R.3
-
2
-
-
0035960866
-
Head and neck cancer
-
Forastiere, A., Koch, W., Trotti, A., and Sidransky, D. 2001. Head and neck cancer. N. Engl. J. Med. 345:1890-1900.
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 1890-1900
-
-
Forastiere, A.1
Koch, W.2
Trotti, A.3
Sidransky, D.4
-
3
-
-
0034235567
-
Identification of new minimally lost regions on 18q in head and neck squamous cell carcinoma
-
Takebayashi, S., et al. 2000. Identification of new minimally lost regions on 18q in head and neck squamous cell carcinoma. Cancer Res. 60:3397-3403. (Pubitemid 30482154)
-
(2000)
Cancer Research
, vol.60
, Issue.13
, pp. 3397-3403
-
-
Takebayashi, S.1
Ogawa, T.2
Jung, K.-Y.3
Muallem, A.4
Mineta, H.5
Fisher, S.G.6
Grenman, R.7
Carey, T.E.8
-
4
-
-
0000799313
-
DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma
-
Kim, S.K., et al. 1996. DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma. Cancer Res. 56:2519-2521. (Pubitemid 26170686)
-
(1996)
Cancer Research
, vol.56
, Issue.11
, pp. 2519-2521
-
-
Kim, S.K.1
Fan, Y.2
Papadimitrakopoulou, V.3
Clayman, G.4
Hittelman, W.N.5
Hong, W.K.6
Lotan, R.7
Mao, L.8
-
5
-
-
0031946721
-
Presence of multiple incontiguous deleted regions at the long arm of chromosome 18 in head and neck cancer
-
Papadimitrakopoulou, V.A., et al. 1998. Presence of multiple incontiguous deleted regions at the long arm of chromosome 18 in head and neck cancer. Clin. Cancer Res. 4:539-544.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 539-544
-
-
Papadimitrakopoulou, V.A.1
-
6
-
-
33745225604
-
Genome-wide profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization
-
DOI 10.1097/01.mlg.0000205141.54471.7f, PII 0000553720060500000010
-
Sparano, A., et al. 2006. Genome-wide profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization. Laryngoscope. 116:735-741. (Pubitemid 44318029)
-
(2006)
Laryngoscope
, vol.116
, Issue.5
, pp. 735-741
-
-
Sparano, A.1
Quesnelle, K.M.2
Kumar, M.S.3
Wang, Y.4
Sylvester, A.J.5
Feldman, M.6
Sewell, D.A.7
Weinstein, G.S.8
Brose, M.S.9
-
7
-
-
33749354957
-
Mouse models for human head and neck squamous cell carcinomas
-
DOI 10.1002/hed.20397
-
Lu, S.L., Herrington, H., and Wang, X.J. 2006. Mouse models for human head and neck squamous cell carcinomas. Head Neck. 28:945-954. (Pubitemid 44497871)
-
(2006)
Head and Neck
, vol.28
, Issue.10
, pp. 945-954
-
-
Lu, S.-L.1
Herrington, H.2
Wang, X.-J.3
-
8
-
-
33646537475
-
Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma
-
Lu, S.L., et al. 2006. Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma. Genes Dev. 20:1331-1342.
-
(2006)
Genes Dev.
, vol.20
, pp. 1331-1342
-
-
Lu, S.L.1
-
9
-
-
3442883361
-
Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity
-
DOI 10.1158/0008-5472.CAN-04-1488
-
Caulin, C., et al. 2004. Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity. Cancer Res. 64:5054-5058. (Pubitemid 39006517)
-
(2004)
Cancer Research
, vol.64
, Issue.15
, pp. 5054-5058
-
-
Caulin, C.1
Nguyen, T.2
Longley, M.A.3
Zhou, Z.4
Wang, X.-J.5
Roop, D.R.6
-
10
-
-
0037228326
-
High incidence of head and neck squamous cell carcinoma in patients with Fanconi anemia
-
Kutler, D.I., et al. 2003. High incidence of head and neck squamous cell carcinoma in patients with Fanconi anemia. Arch. Otolaryngol. Head Neck Surg. 129:106-112. (Pubitemid 36070885)
-
(2003)
Archives of Otolaryngology - Head and Neck Surgery
, vol.129
, Issue.1
, pp. 106-112
-
-
Kutler, D.I.1
Auerbach, A.D.2
Satagopan, J.3
Giampietro, P.F.4
Batish, S.D.5
Huvos, A.G.6
Goberdhan, A.7
Shah, J.P.8
Singh, B.9
-
11
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn, S.A., et al. 1996. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science. 271:350-353. (Pubitemid 3021510)
-
(1996)
Science
, vol.271
, Issue.5247
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
12
-
-
0029786212
-
Receptor-associated Mad homologues synergize as effectors of the TGF-beta response
-
DOI 10.1038/383168a0
-
Zhang, Y., Feng, X., We, R., and Derynck, R. 1996. Receptor-associated Mad homologues synergize as effectors of the TGF-beta response. Nature. 383:168-172. (Pubitemid 26303979)
-
(1996)
Nature
, vol.383
, Issue.6596
, pp. 168-172
-
-
Zhang, Y.1
Feng, X.-H.2
Wu, R.-Y.3
Derynck, R.4
-
13
-
-
0242499448
-
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
-
Siegel, P.M., and Massague, J. 2003. Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat. Rev. Cancer. 3:807-821. (Pubitemid 37376979)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.11
, pp. 807-820
-
-
Siegel, P.M.1
Massague, J.2
-
15
-
-
34047138860
-
+ myeloid cells that promote invasion
-
DOI 10.1038/ng1997, PII NG1997
-
Kitamura, T., et al. 2007. SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. Nat. Genet. 39:467-475. (Pubitemid 46514777)
-
(2007)
Nature Genetics
, vol.39
, Issue.4
, pp. 467-475
-
-
Kitamura, T.1
Kometani, K.2
Hashida, H.3
Matsunaga, A.4
Miyoshi, H.5
Hosogi, H.6
Aoki, M.7
Oshima, M.8
Hattori, M.9
Takabayashi, A.10
Minato, N.11
Taketo, M.M.12
-
16
-
-
0032489508
-
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
-
DOI 10.1016/S0092-8674(00)81132-0
-
Takaku, K., et al. 1998. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell. 92:645-656. (Pubitemid 28141513)
-
(1998)
Cell
, vol.92
, Issue.5
, pp. 645-656
-
-
Takaku, K.1
Oshima, M.2
Miyoshi, H.3
Matsui, M.4
Seldin, M.F.5
Taketo, M.M.6
-
17
-
-
33847387472
-
G12D and Smad4/Dpc4 Haploinsufficiency Cooperate to Induce Mucinous Cystic Neoplasms and Invasive Adenocarcinoma of the Pancreas
-
DOI 10.1016/j.ccr.2007.01.017, PII S1535610807000578
-
Izeradjene, K., et al. 2007. Kras(G12D) and Smad4/ Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas. Cancer Cell. 11:229-243. (Pubitemid 46349845)
-
(2007)
Cancer Cell
, vol.11
, Issue.3
, pp. 229-243
-
-
Izeradjene, K.1
Combs, C.2
Best, M.3
Gopinathan, A.4
Wagner, A.5
Grady, W.M.6
Deng, C.-X.7
Hruban, R.H.8
Adsay, N.V.9
Tuveson, D.A.10
Hingorani, S.R.11
-
18
-
-
33751251034
-
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer
-
DOI 10.1101/gad.1478706
-
Bardeesy, N., et al. 2006. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. Genes Dev. 20:3130-3146. (Pubitemid 44790628)
-
(2006)
Genes and Development
, vol.20
, Issue.22
, pp. 3130-3146
-
-
Bardeesy, N.1
Cheng, K.-H.2
Berger, J.H.3
Chu, G.C.4
Pahler, J.5
Olson, P.6
Hezel, A.F.7
Horner, J.8
Lauwers, G.Y.9
Hanahan, D.10
Depinho, R.A.11
-
19
-
-
33746919897
-
Synergistic function of Smad4 and PTEN in suppressing forestomach squamous cell carcinoma in the mouse
-
DOI 10.1158/0008-5472.CAN-06-0507
-
Teng, Y., et al. 2006. Synergistic function of Smad4 and PTEN in suppressing forestomach squamous cell carcinoma in the mouse. Cancer Res. 66:6972-6981. (Pubitemid 44197672)
-
(2006)
Cancer Research
, vol.66
, Issue.14
, pp. 6972-6981
-
-
Teng, Y.1
Sun, A.-N.2
Pan, X.-C.3
Yang, G.4
Yang, L.-L.5
Wang, M.-R.6
Yang, X.7
-
20
-
-
33745856213
-
Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice
-
DOI 10.1172/JCI27282
-
Xu, X., et al. 2006. Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. J. Clin. Invest. 116:1843-1852. (Pubitemid 44033309)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1843-1852
-
-
Xu, X.1
Kobayashi, S.2
Qiao, W.3
Li, C.4
Xiao, C.5
Radaeva, S.6
Stiles, B.7
Wang, R.-H.8
Ohara, N.9
Yoshino, T.10
Leroith, D.11
Torbenson, M.S.12
Gores, G.J.13
Wu, H.14
Gao, B.15
Deng, C.-X.16
-
21
-
-
0034611611
-
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice
-
Xu, X., et al. 2000. Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice. Oncogene. 19:1868-1874. (Pubitemid 30219029)
-
(2000)
Oncogene
, vol.19
, Issue.15
, pp. 1868-1874
-
-
Xu, X.1
Brodie, S.G.2
Yang, X.3
Im, Y.-H.4
Parks, W.T.5
Chen, L.6
Zhou, Y.-X.7
Weinstein, M.8
Kim, S.-J.9
Deng, C.-X.10
-
22
-
-
30544444184
-
Hair follicle defects and squamous cell carcinoma formation in Smad4 conditional knockout mouse skin
-
DOI 10.1038/sj.onc.1209029, PII 1209029
-
Qiao, W., et al. 2006. Hair follicle defects and squamous cell carcinoma formation in Smad4 conditional knockout mouse skin. Oncogene. 25:207-217. (Pubitemid 43083682)
-
(2006)
Oncogene
, vol.25
, Issue.2
, pp. 207-217
-
-
Qiao, W.1
Li, A.G.2
Owens, P.3
Xu, X.4
Wang, X.-J.5
Deng, C.-X.6
-
23
-
-
10744224096
-
Squamous cell carcinoma and mammary abscess formation through squamous metaplasia in Smad4/Dpc4 conditional knockout mice
-
DOI 10.1242/dev.00820
-
Li, W., et al. 2003. Squamous cell carcinoma and mammary abscess formation through squamous metaplasia in Smad4/Dpc4 conditional knockout mice. Development. 130:6143-6153. (Pubitemid 38008814)
-
(2003)
Development
, vol.130
, Issue.24
, pp. 6143-6153
-
-
Li, W.1
Qiao, W.2
Chen, L.3
Xu, X.4
Yang, X.5
Li, D.6
Li, C.7
Brodie, S.G.8
Meguid, M.M.9
Hennighausen, L.10
Deng, C.-X.11
-
24
-
-
25444473619
-
Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors
-
DOI 10.1158/0008-5472.CAN-05-0800
-
Yang, L., et al. 2005. Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors. Cancer Res. 65:8671-8678. (Pubitemid 41377354)
-
(2005)
Cancer Research
, vol.65
, Issue.19
, pp. 8671-8678
-
-
Yang, L.1
Mao, C.2
Teng, Y.3
Li, W.4
Zhang, J.5
Cheng, X.6
Li, X.7
Han, X.8
Xia, Z.9
Deng, H.10
Yang, X.11
-
25
-
-
20544465379
-
Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma
-
Snijders, A.M., et al. 2005. Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma. Oncogene. 24:4232-4242.
-
(2005)
Oncogene
, vol.24
, pp. 4232-4242
-
-
Snijders, A.M.1
-
26
-
-
0037103055
-
Decreased Smad4 expression in the transforming growth factor-beta signaling pathway during progression of esophageal squamous cell carcinoma
-
DOI 10.1002/cncr.10727
-
Fukuchi, M., et al. 2002. Decreased Smad4 expression in the transforming growth factor-beta signaling pathway during progression of esophageal squamous cell carcinoma. Cancer. 95:737-743. (Pubitemid 34839664)
-
(2002)
Cancer
, vol.95
, Issue.4
, pp. 737-743
-
-
Fukuchi, M.1
Masuda, N.2
Miyazaki, T.3
Nakajima, M.4
Osawa, H.5
Kato, H.6
Kuwano, H.7
-
27
-
-
0036281395
-
Smad4 and transforming growth factor beta1 expression in patients with squamous cell carcinoma of the esophagus
-
Natsugoe, S., et al. 2002. Smad4 and transforming growth factor beta1 expression in patients with squamous cell carcinoma of the esophagus. Clin. Cancer Res. 8:1838-1842. (Pubitemid 34633743)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.6
, pp. 1838-1842
-
-
Natsugoe, S.1
Xiangming, C.2
Matsumoto, M.3
Okumura, H.4
Nakashima, S.5
Sakita, H.6
Ishigami, S.7
Baba, M.8
Takao, S.9
Aikou, T.10
-
28
-
-
0031850583
-
Gene expression of differentiation-specific keratins (4/13 and 1/10) in normal human buccal mucosa
-
Bloor, B.K., Su, L., Shirlaw, P.J., and Morgan, P.R. 1998. Gene expression of differentiation-specific keratins (4/13 and 1/10) in normal human buccal mucosa. Lab. Invest. 78:787-795. (Pubitemid 28347876)
-
(1998)
Laboratory Investigation
, vol.78
, Issue.7
, pp. 787-795
-
-
Bloor, B.K.1
Su, L.2
Shirlaw, P.J.3
Morgan, P.R.4
-
30
-
-
0345304254
-
Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells
-
DOI 10.1038/sj.onc.1206998
-
Bertrand, P., Lambert, S., Joubert, C., and Lopez, B.S. 2003. Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant- negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells. Oncogene. 22:7587-7592. (Pubitemid 37464091)
-
(2003)
Oncogene
, vol.22
, Issue.48
, pp. 7587-7592
-
-
Bertrand, P.1
Lambert, S.2
Joubert, C.3
Lopez, B.S.4
-
31
-
-
0033106326
-
2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
-
DOI 10.1016/S1097-2765(00)80466-9
-
Xu, X., et al. 1999. Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Mol. Cell. 3:389-395. (Pubitemid 29290679)
-
(1999)
Molecular Cell
, vol.3
, Issue.3
, pp. 389-395
-
-
Xu, X.1
Weaver, Z.2
Linke, S.P.3
Li, C.4
Gotay, J.5
Wang, X.-W.6
Harris, C.C.7
Ried, T.8
Deng, C.-X.9
-
32
-
-
36448987217
-
Oncogenes and tumour suppressors take on centrosomes
-
DOI 10.1038/nrc2249, PII NRC2249
-
Fukasawa, K. 2007. Oncogenes and tumour suppressors take on centrosomes. Nat. Rev. Cancer. 7:911-924. (Pubitemid 350165854)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.12
, pp. 911-924
-
-
Fukasawa, K.1
-
33
-
-
5444264596
-
Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck
-
DOI 10.1200/JCO.2004.01.094
-
Wreesmann, V.B., et al. 2004. Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck. J. Clin. Oncol. 22:3965-3972. (Pubitemid 41079879)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.19
, pp. 3965-3972
-
-
Wreesmann, V.B.1
Shi, W.2
Thaler, H.T.3
Poluri, A.4
Kraus, D.H.5
Pfister, D.6
Shaha, A.R.7
Shah, J.P.8
Rao, P.H.9
Singh, B.10
-
34
-
-
0348226631
-
Genetic abnormalities associated with nodal metastasis in head and neck cancer
-
DOI 10.1002/hed.10344
-
Wreesmann, V.B., et al. 2004. Genetic abnormalities associated with nodal metastasis in head and neck cancer. Head Neck. 26:10-15. (Pubitemid 38030144)
-
(2004)
Head and Neck
, vol.26
, Issue.1
, pp. 10-15
-
-
Wreesmann, V.B.1
Wang, D.2
Goberdhan, A.3
Prasad, M.4
Ngai, I.5
Schnaser, E.A.6
Sacks, P.G.7
Singh, B.8
-
35
-
-
33846144441
-
Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma
-
DOI 10.1001/jama.297.2.187
-
Weber, F., et al. 2007. Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma. JAMA. 297:187-195. (Pubitemid 46089735)
-
(2007)
Journal of the American Medical Association
, vol.297
, Issue.2
, pp. 187-195
-
-
Weber, F.1
Xu, Y.2
Zhang, L.3
Patocs, A.4
Shen, L.5
Platzer, P.6
Eng, C.7
-
36
-
-
29144506137
-
The Fanconi Anemia/BRCA pathway: New faces in the crowd
-
Kennedy, R.D., and D'Andrea, A.D. 2005. The Fanconi Anemia/BRCA pathway: new faces in the crowd. Genes Dev. 19:2925-2940.
-
(2005)
Genes Dev.
, vol.19
, pp. 2925-2940
-
-
Kennedy, R.D.1
D'Andrea, A.D.2
-
37
-
-
33845683318
-
Disruption of transforming growth factor beta-Smad signaling pathway in head and neck squamous cell carcinoma as evidenced by mutations of SMAD2 and SMAD4
-
DOI 10.1016/j.canlet.2006.01.003, PII S0304383506000279
-
Qiu, W., Schonleben, F., Li, X., and Su, G.H. 2007. Disruption of transforming growth factor beta-Smad signaling pathway in head and neck squamous cell carcinoma as evidenced by mutations of SMAD2 and SMAD4. Cancer Lett. 245:163-170. (Pubitemid 44959352)
-
(2007)
Cancer Letters
, vol.245
, Issue.1-2
, pp. 163-170
-
-
Qiu, W.1
Schonleben, F.2
Li, X.3
Su, G.H.4
-
38
-
-
0037268338
-
The Fanconi anaemia/BRCA pathway
-
D'Andrea, A.D., and Grompe, M. 2003. The Fanconi anaemia/BRCA pathway. Nat. Rev. Cancer. 3:23-34.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 23-34
-
-
D'Andrea, A.D.1
Grompe, M.2
-
39
-
-
3042531148
-
Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: A potential target for UCN-01
-
DOI 10.1158/1078-0432.CCR-03-0249
-
Amornphimoltham, P., et al. 2004. Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: a potential target for UCN-01. Clin. Cancer Res. 10:4029-4037. (Pubitemid 38812478)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.12 I
, pp. 4029-4037
-
-
Amornphimoltham, P.1
Sriuranpong, V.2
Patel, V.3
Benavides, F.4
Conti, C.J.5
Sauk, J.6
Sausville, E.A.7
Molinolo, A.A.8
Gutkind, J.S.9
-
40
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan, P.R., et al. 2006. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature. 441:231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
-
41
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
DOI 10.1016/j.immuni.2006.01.001, PII S1074761306000045
-
Veldhoen, M., Hocking, R.J., Atkins, C.J., Locksley, R.M., and Stockinger, B. 2006. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 24:179-189. (Pubitemid 43214587)
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
42
-
-
2442548490
-
Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder
-
DOI 10.1038/sj.emboj.7600183
-
Li, A.G., Wang, D., Feng, X.H., and Wang, X.J. 2004. Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder. EMBO J. 23:1770-1781. (Pubitemid 38649640)
-
(2004)
EMBO Journal
, vol.23
, Issue.8
, pp. 1770-1781
-
-
Li, A.G.1
Wang, D.2
Feng, X.-H.3
Wang, X.-J.4
-
43
-
-
3042778716
-
Overexpression of transforming growth factor beta1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation
-
Lu, S.L., et al. 2004. Overexpression of transforming growth factor beta1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation. Cancer Res. 64:4405-4410.
-
(2004)
Cancer Res.
, vol.64
, pp. 4405-4410
-
-
Lu, S.L.1
-
44
-
-
7444272649
-
Smad3 knockout mice exhibit a resistance to skin chemical carcinogenesis
-
DOI 10.1158/0008-5472.CAN-04-1331
-
Li, A.G., Lu, S.L., Zhang, M.X., Deng, C., and Wang, X.J. 2004. Smad3 knockout mice exhibit a resistance to skin chemical carcinogenesis. Cancer Res. 64:7836-7845. (Pubitemid 39446916)
-
(2004)
Cancer Research
, vol.64
, Issue.21
, pp. 7836-7845
-
-
Li, A.G.1
Lu, S.-L.2
Zhang, M.-X.3
Deng, C.4
Wang, X.-J.5
-
45
-
-
34250658382
-
Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma
-
DOI 10.1159/000101542
-
Wreesmann, V.B., Estilo, C., Eisele, D.W., Singh, B., and Wang, S.J. 2007. Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma. ORL J. Otorhinolaryngol. Relat. Spec. 69:218-225. (Pubitemid 46934196)
-
(2007)
ORL
, vol.69
, Issue.4
, pp. 218-225
-
-
Wreesmann, V.B.1
Estilo, C.2
Eisele, D.W.3
Singh, B.4
Wang, S.J.5
-
46
-
-
1342301467
-
Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: Implications for treatment and survival
-
Marsit, C.J., et al. 2004. Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival. Oncogene. 23:1000-1004.
-
(2004)
Oncogene
, vol.23
, pp. 1000-1004
-
-
Marsit, C.J.1
-
47
-
-
0042836597
-
Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues
-
DOI 10.1038/sj.onc.1206825
-
Berton, T.R., et al. 2003. Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues. Oncogene. 22:5415-5426. (Pubitemid 37072196)
-
(2003)
Oncogene
, vol.22
, Issue.35
, pp. 5415-5426
-
-
Berton, T.R.1
Matsumoto, T.2
Page, A.3
Conti, C.J.4
Deng, C.-X.5
Jorcano, J.L.6
Johnson, D.G.7
-
48
-
-
0036500132
-
Functional proteomics of transforming growth factor-beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbeta1-dependent regulation of DNA repair
-
DOI 10.1093/emboj/21.5.1219
-
Kanamoto, T., Hellman, U., Heldin, C.H., and Souchelnytskyi, S. 2002. Functional proteomics of transforming growth factor-beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbeta1-dependent regulation of DNA repair. EMBO J. 21:1219-1230. (Pubitemid 34206195)
-
(2002)
EMBO Journal
, vol.21
, Issue.5
, pp. 1219-1230
-
-
Kanamoto, T.1
Hellman, U.2
Heldin, C.-H.3
Souchelnytskyi, S.4
-
49
-
-
16444384985
-
TGFbeta1/Smad3 counteracts BRCA1-dependent repair of DNA damage
-
DOI 10.1038/sj.onc.1208443
-
Dubrovska, A., et al. 2005. TGFbeta1/Smad3 counteracts BRCA1-dependent repair of DNA damage. Oncogene. 24:2289-2297. (Pubitemid 40546688)
-
(2005)
Oncogene
, vol.24
, Issue.14
, pp. 2289-2297
-
-
Dubrovska, A.1
Kanamoto, T.2
Lomnytska, M.3
Heldin, C.-H.4
Volodko, N.5
Souchelnytskyi, S.6
-
50
-
-
0033017066
-
Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer
-
Chen, Z., et al. 1999. Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer. Clin. Cancer Res. 5:1369-1379. (Pubitemid 29282941)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.6
, pp. 1369-1379
-
-
Chen, Z.1
Malhotra, P.S.2
Thomas, G.R.3
Ondrey, F.G.4
Duffey, D.C.5
Smith, C.W.6
Enamorado, I.7
Yeh, N.T.8
Kroog, G.S.9
Rudy, S.10
McCullagh, L.11
Mousa, S.12
Quezado, M.13
Herscher, L.L.14
Van Waes, C.15
-
51
-
-
33745578957
-
Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
-
Kim, B.G., et al. 2006. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Nature. 441:1015-1019.
-
(2006)
Nature
, vol.441
, pp. 1015-1019
-
-
Kim, B.G.1
-
52
-
-
0035984569
-
Activation of bone morphogenetic protein/smad signaling in bronchial epithelial cells during airway inflammation
-
Rosendahl, A., et al. 2002. Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation. Am. J. Respir. Cell Mol. Biol. 27:160-169. (Pubitemid 34780795)
-
(2002)
American Journal of Respiratory Cell and Molecular Biology
, vol.27
, Issue.2
, pp. 160-169
-
-
Rosendahl, A.1
Pardali, E.2
Speletas, M.3
Ten Dijke, P.4
Heldin, C.-H.5
Sideras, P.6
-
53
-
-
40949083607
-
Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype
-
Bharathy, S., Xie, W., Yingling, J.M., and Reiss, M. 2008. Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype. Cancer Res. 68:1656-1666.
-
(2008)
Cancer Res.
, vol.68
, pp. 1656-1666
-
-
Bharathy, S.1
Xie, W.2
Yingling, J.M.3
Reiss, M.4
-
54
-
-
58749089988
-
TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch
-
Liu, I.M., et al. 2009. TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch. EMBO J. 28:88-98.
-
(2009)
EMBO J.
, vol.28
, pp. 88-98
-
-
Liu, I.M.1
-
55
-
-
34547857048
-
Distinct roles of individual Smads in skin carcinogenesis
-
DOI 10.1002/mc.20336
-
Bornstein, S., Hoot, K., Han, G.W., Lu, S.L., and Wang, X.J. 2007. Distinct roles of individual Smads in skin carcinogenesis. Mol. Carcinog. 46:660-664. (Pubitemid 47255184)
-
(2007)
Molecular Carcinogenesis
, vol.46
, Issue.8
, pp. 660-664
-
-
Bornstein, S.1
Hoot, K.2
Han, G.-W.3
Lu, S.-L.4
Wang, X.-J.5
-
56
-
-
0035125764
-
A distinct expression of CC chemokines by macrophages in nasopharyngeal carcinoma: Implication for the intense tumor infiltration by T lymphocytes and macrophages
-
Tang, K.F., et al. 2001. A distinct expression of CC chemokines by macrophages in nasopharyngeal carcinoma: implication for the intense tumor infiltration by T lymphocytes and macrophages. Hum. Pathol. 32:42-49.
-
(2001)
Hum. Pathol.
, vol.32
, pp. 42-49
-
-
Tang, K.F.1
-
57
-
-
34548262577
-
Clinical significance of MMP-2 and MMP-9 in patients with oral cancer
-
DOI 10.1002/hed.20561
-
Patel, B.P., Shah, S.V., Shukla, S.N., Shah, P.M., and Patel, P.S. 2007. Clinical significance of MMP-2 and MMP-9 in patients with oral cancer. Head Neck. 29:564-572. (Pubitemid 47324773)
-
(2007)
Head and Neck
, vol.29
, Issue.6
, pp. 564-572
-
-
Patel, B.P.1
Shah, S.V.2
Shukla, S.N.3
Shah, P.M.4
Patel, P.S.5
-
58
-
-
47849098044
-
Inflammation: Gearing the journey to cancer
-
Kundu, J.K., and Surh, Y.J. 2008. Inflammation: gearing the journey to cancer. Mutat. Res. 659:15-30.
-
(2008)
Mutat. Res.
, vol.659
, pp. 15-30
-
-
Kundu, J.K.1
Surh, Y.J.2
-
59
-
-
0035105291
-
Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway
-
DOI 10.1016/S1097-2765(01)00173-3
-
Garcia-Higuera, I., et al. 2001. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol. Cell. 7:249-262. (Pubitemid 32206493)
-
(2001)
Molecular Cell
, vol.7
, Issue.2
, pp. 249-262
-
-
Garcia-Higuera, I.1
Taniguchi, T.2
Ganesan, S.3
Meyn, M.S.4
Timmers, C.5
Hejna, J.6
Grompe, M.7
D'Andrea, A.D.8
-
60
-
-
33947380240
-
Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology
-
DOI 10.1158/1078-0432.CCR-06-2260
-
Ratnam, K., and Low, J.A. 2007. Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology. Clin. Cancer Res. 13:1383-1388. (Pubitemid 46450426)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.5
, pp. 1383-1388
-
-
Ratnam, K.1
Low, J.A.2
|