-
2
-
-
0014208039
-
Aromatic amino acids and modification of parkinsonism
-
Cotzias GC, Van Woert MH, et al. Aromatic amino acids and modification of parkinsonism. N Engl J Med 1967;276:374-379
-
(1967)
N Engl J Med
, vol.276
, pp. 374-379
-
-
Cotzias, G.C.1
Van Woert, M.H.2
-
3
-
-
0013861887
-
Treatment of Parkinson's syndrome with l-dopa. A double blind study
-
Fehling C. Treatment of Parkinson's syndrome with l-dopa. A double blind study. Acta Neurol Scand 1966;42:367-372
-
(1966)
Acta Neurol Scand
, vol.42
, pp. 367-372
-
-
Fehling, C.1
-
4
-
-
0035353725
-
Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature
-
Ahlskog JE, Muenter MD. Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov Disord 2001;16:448-458
-
(2001)
Mov Disord
, vol.16
, pp. 448-458
-
-
Ahlskog, J.E.1
Muenter, M.D.2
-
5
-
-
62349123821
-
Nitric oxide synthase inhibition attenuates l-DOPA-induced dyskinesias in a rodent model of Parkinson's disease
-
Padovan-Neto FE, Echeverry MB, Tumas V, Del-Bel EA. Nitric oxide synthase inhibition attenuates l-DOPA-induced dyskinesias in a rodent model of Parkinson's disease. Neuroscience 2009;159:925-935
-
(2009)
Neuroscience
, vol.159
, pp. 925-935
-
-
Padovan-Neto, F.E.1
Echeverry, M.B.2
Tumas, V.3
Del-Bel, E.A.4
-
6
-
-
0038159674
-
Dopamine- or l-DOPA-induced neurotoxicity: The role of dopamine quinone formation and tyrosinase in a model of Parkinson's disease
-
Asanuma M, Miyazaki I, Ogawa N. Dopamine- or l-DOPA-induced neurotoxicity: the role of dopamine quinone formation and tyrosinase in a model of Parkinson's disease. Neurotox Res 2003;5:165-176
-
(2003)
Neurotox Res
, vol.5
, pp. 165-176
-
-
Asanuma, M.1
Miyazaki, I.2
Ogawa, N.3
-
7
-
-
0042847323
-
Chronic stimulation of D1 dopamine receptors in human SK-N-MC neuroblastoma cells induces nitric-oxide synthase activation and cytotoxicity
-
Chen J, Wersinger C, Sidhu A. Chronic stimulation of D1 dopamine receptors in human SK-N-MC neuroblastoma cells induces nitric-oxide synthase activation and cytotoxicity. J Biol Chem 2003;278:28089-28100
-
(2003)
J Biol Chem
, vol.278
, pp. 28089-28100
-
-
Chen, J.1
Wersinger, C.2
Sidhu, A.3
-
8
-
-
0037195548
-
LevoDOPA modulating effects of inducible nitric oxide synthase and reactive oxygen species in glioma cells
-
Soliman MK, Mazzio E, Soliman KF. levoDOPA modulating effects of inducible nitric oxide synthase and reactive oxygen species in glioma cells. life Sci 2002;72:185-198
-
(2002)
Life Sci
, vol.72
, pp. 185-198
-
-
Soliman, M.K.1
Mazzio, E.2
Soliman, K.F.3
-
9
-
-
2542427512
-
Nitric oxide neurotoxicity in neurodegenerative diseases
-
Boje KM. Nitric oxide neurotoxicity in neurodegenerative diseases. Front Biosci 2004;9:763-776
-
(2004)
Front Biosci
, vol.9
, pp. 763-776
-
-
Boje, K.M.1
-
10
-
-
0026531427
-
Neurotoxicity of levoDOPA on catecholamine-rich neurons
-
Mena MA, Pardo B, Casarejos MJ, et al. Neurotoxicity of levoDOPA on catecholamine-rich neurons. Mov Disord 1992;7:23-31
-
(1992)
Mov Disord
, vol.7
, pp. 23-31
-
-
Mena, M.A.1
Pardo, B.2
Casarejos, M.J.3
-
11
-
-
0027462802
-
LevoDOPA toxicity in foetal rat midbrain neurones in culture: Modulation by ascorbic acid
-
Mena MA, Pardo B, Paino Cl, et al. levoDOPA toxicity in foetal rat midbrain neurones in culture: modulation by ascorbic acid. Neuroreport 1993;4:438-440
-
(1993)
Neuroreport
, vol.4
, pp. 438-440
-
-
Mena, M.A.1
Pardo, B.2
Cl, P.3
-
12
-
-
0025245453
-
Chronic levoDOPA impairs morphological development of grafted embryonic dopamine neurons
-
Steece-Collier K, Collier TJ, Sladek CD, et al. Chronic levoDOPA impairs morphological development of grafted embryonic dopamine neurons. Exp Neurol 1990;110:201-208
-
(1990)
Exp Neurol
, vol.110
, pp. 201-208
-
-
Steece-Collier, K.1
Collier, T.J.2
Sladek, C.D.3
-
13
-
-
0026061854
-
DOPA and dopamine cause cultured neuronal death in the presence of iron
-
Tanaka M, Sotomatsu A, Kanai H, et al. DOPA and dopamine cause cultured neuronal death in the presence of iron. J Neurol Sci 1991;101:198-203
-
(1991)
J Neurol Sci
, vol.101
, pp. 198-203
-
-
Tanaka, M.1
Sotomatsu, A.2
Kanai, H.3
-
14
-
-
0029051317
-
Induction of apoptosis in catecholaminergic PC12 cells by l-DOPA. Implications for the treatment of Parkinson's disease
-
Walkinshaw G, Waters CM. Induction of apoptosis in catecholaminergic PC12 cells by l-DOPA. Implications for the treatment of Parkinson's disease. J Clin Invest 1995;95:2458-2464
-
(1995)
J Clin Invest
, vol.95
, pp. 2458-2464
-
-
Walkinshaw, G.1
Waters, C.M.2
-
15
-
-
28444441920
-
L-DOPA administration enhances 6-hydroxydopamine generation
-
Maharaj H, Sukhdev Maharaj D, Scheepers M, et al. l-DOPA administration enhances 6-hydroxydopamine generation. Brain Res 2005;1063:180-186
-
(2005)
Brain Res
, vol.1063
, pp. 180-186
-
-
Maharaj, H.1
Sukhdev Maharaj, D.2
Scheepers, M.3
-
17
-
-
29144508700
-
Plasma lipid peroxidation in sporadic Parkinson's disease. Role of the l-dopa
-
Agil A, Duran R, Barrero F, et al. Plasma lipid peroxidation in sporadic Parkinson's disease. Role of the l-dopa. J Neurol Sci 2006;240:31-36
-
(2006)
J Neurol Sci
, vol.240
, pp. 31-36
-
-
Agil, A.1
Duran, R.2
Barrero, F.3
-
18
-
-
0027362832
-
Toxic and protective effects of l-DOPA on mesencephalic cell cultures
-
Mytilineou C, Han SK, Cohen G. Toxic and protective effects of l-DOPA on mesencephalic cell cultures. J Neurochem 1993;61:1470-1478
-
(1993)
J Neurochem
, vol.61
, pp. 1470-1478
-
-
Mytilineou, C.1
Han, S.K.2
Cohen, G.3
-
19
-
-
26644437449
-
LevoDOPA therapy from the neuroprotection viewpoint. from a clinical outlook
-
Kondo T. levoDOPA therapy from the neuroprotection viewpoint. From a clinical outlook. J Neurol 2005;252:IV32-36
-
(2005)
J Neurol
, vol.252
-
-
Kondo, T.1
-
20
-
-
0019026208
-
Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
-
Embi N, Rylatt DB, Cohen P. Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 1980;107:519-527
-
(1980)
Eur J Biochem
, vol.107
, pp. 519-527
-
-
Embi, N.1
Rylatt, D.B.2
Cohen, P.3
-
21
-
-
0442276554
-
The glamour and gloom of glycogen synthase kinase-3
-
Jope RS, Johnson GV. The glamour and gloom of glycogen synthase kinase-3. Trends Biochem Sci 2004;29:95-102
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 95-102
-
-
Jope, R.S.1
Johnson, G.V.2
-
22
-
-
0033773645
-
Opposing actions of phosphatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSF-1 activity
-
Bijur GN, Jope RS. Opposing actions of phosphatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSF-1 activity. J Neurochem 2000;75:2401-2408
-
(2000)
J Neurochem
, vol.75
, pp. 2401-2408
-
-
Bijur, G.N.1
Jope, R.S.2
-
23
-
-
0035813212
-
Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta
-
Bijur GN, Jope RS. Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta. J Biol Chem 2001;276:37436-37442
-
(2001)
J Biol Chem
, vol.276
, pp. 37436-37442
-
-
Bijur, G.N.1
Jope, R.S.2
-
24
-
-
0034859101
-
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
-
Grimes CA, Jope RS. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol 2001;65:391-426
-
(2001)
Prog Neurobiol
, vol.65
, pp. 391-426
-
-
Grimes, C.A.1
Jope, R.S.2
-
25
-
-
10744223843
-
Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3
-
Koh SH, Kim SH, Kwon H, et al. Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3. Brain Res Mol Brain Res 2003;118:72-81
-
(2003)
Brain Res Mol Brain Res
, vol.118
, pp. 72-81
-
-
Koh, S.H.1
Kim, S.H.2
Kwon, H.3
-
26
-
-
3543001698
-
Phosphatidylinositol-3 kinase/Akt and GSK-3 mediated cytoprotective effect of epigallocatechin gallate on oxidative stress-injured neuronal-differentiated N18D3 cells
-
Koh SH, Kim SH, Kwon H, et al. Phosphatidylinositol-3 kinase/Akt and GSK-3 mediated cytoprotective effect of epigallocatechin gallate on oxidative stress-injured neuronal-differentiated N18D3 cells. Neurotoxicology 2004;25:793-802
-
(2004)
Neurotoxicology
, vol.25
, pp. 793-802
-
-
Koh, S.H.1
Kim, S.H.2
Kwon, H.3
-
27
-
-
4544304149
-
Glycogen synthase kinase-3 inhibitors prevent caspase-dependent apoptosis induced by ethanol in cultured rat cortical neurons
-
DOI 10.1016/j.ejphar.2004.07.115, PII S0014299904009100
-
Takadera T, Ohyashiki T. Glycogen synthase kinase-3 inhibitors prevent caspase-dependent apoptosis induced by ethanol in cultured rat cortical neurons. Eur J Pharmacol 2004;499:239-245 (Pubitemid 39233662)
-
(2004)
European Journal of Pharmacology
, vol.499
, Issue.3
, pp. 239-245
-
-
Takadera, T.1
Ohyashiki, T.2
-
28
-
-
0442274617
-
Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53
-
Watcharasit P, Bijur GN, Song l, et al. Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. J Biol Chem 2003;278:48872-48879
-
(2003)
J Biol Chem
, vol.278
, pp. 48872-48879
-
-
Watcharasit, P.1
Bijur, G.N.2
Song, L.3
-
29
-
-
9444257518
-
Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine- induced neuronal death
-
Chen G, Bower KA, Ma C, et al. Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death. FASEB J 2004;18:1162-1164
-
(2004)
FASEB J
, vol.18
, pp. 1162-1164
-
-
Chen, G.1
Bower, K.A.2
Ma, C.3
-
30
-
-
42749091984
-
Inhibition of glycogen synthase kinase-3 reduces l-DOPA-induced neurotoxicity
-
Koh SH, Song C, Noh MY, et al. Inhibition of glycogen synthase kinase-3 reduces l-DOPA-induced neurotoxicity. Toxicology 2008;247:112-118
-
(2008)
Toxicology
, vol.247
, pp. 112-118
-
-
Koh, S.H.1
Song, C.2
Noh, M.Y.3
-
31
-
-
34547467082
-
Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration
-
Caudle WM, Richardson JR, Wang MZ, et al. Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration. J Neurosci 2007;27:8138-8148
-
(2007)
J Neurosci
, vol.27
, pp. 8138-8148
-
-
Caudle, W.M.1
Richardson, J.R.2
Wang, M.Z.3
-
32
-
-
38349027133
-
Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice
-
Chen l, Ding Y, Cagniard B, et al. Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice. J Neurosci 2008;287:425-433
-
(2008)
J Neurosci
, vol.287
, pp. 425-433
-
-
Chen, L.1
Ding, Y.2
Cagniard, B.3
-
33
-
-
0024582213
-
Acute regulation of tyrosine hydroxylase by nerve activity and by neurotransmitters via phosphorylation
-
Zigmond RE, Schwarzschild MA, Rittenhouse AR. Acute regulation of tyrosine hydroxylase by nerve activity and by neurotransmitters via phosphorylation. Annu Rev Neurosci 1989;12:415-461
-
(1989)
Annu Rev Neurosci
, vol.12
, pp. 415-461
-
-
Zigmond, R.E.1
Schwarzschild, M.A.2
Rittenhouse, A.R.3
-
34
-
-
0030017489
-
Intricate regulation of tyrosine hydroxylase activity and gene expression
-
Kumer SC, Vrana KE. Intricate regulation of tyrosine hydroxylase activity and gene expression. J Neurochem 1996;67:443-462
-
(1996)
J Neurochem
, vol.67
, pp. 443-462
-
-
Kumer, S.C.1
Vrana, K.E.2
-
35
-
-
4143144205
-
Catecholamine metabolism: A contemporary view with implications for physiology and medicine
-
Eisenhofer G, Kopin IJ, Goldstein DS. Catecholamine metabolism: a contemporary view with implications for physiology and medicine. Pharmacol Rev 2004;56:331-349
-
(2004)
Pharmacol Rev
, vol.56
, pp. 331-349
-
-
Eisenhofer, G.1
Kopin, I.J.2
Goldstein, D.S.3
-
36
-
-
0035834360
-
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct
-
Conway KA, Rochet JC, Bieganski RM, lansbury PT Jr. Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct. Science 2001;294:1346-1349
-
(2001)
Science
, vol.294
, pp. 1346-1349
-
-
Conway, K.A.1
Rochet, J.C.2
Bieganski, R.M.3
Lansbury Jr., P.T.4
-
37
-
-
33746533924
-
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
-
Cooper AA, Gitler AD, Cashikar A, et al. Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science 2006;313:324-328
-
(2006)
Science
, vol.313
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
-
38
-
-
20444367300
-
Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice
-
Chen l, Cagniard B, Mathews T, et al. Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice. J Biol Chem 2005;280:21418-21426
-
(2005)
J Biol Chem
, vol.280
, pp. 21418-21426
-
-
Chen, L.1
Cagniard, B.2
Mathews, T.3
-
39
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
DOI 10.1126/science.1077209
-
Bonifati V, Rizzu P, van Baren MJ, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003;299:256-259 (Pubitemid 36131051)
-
(2003)
Science
, vol.299
, Issue.5604
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.J.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
Van Dongen, J.W.11
Vanacore, N.12
Van Swieten, J.C.13
Brice, A.14
Meco, G.15
Van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
40
-
-
0141891953
-
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
-
Goldberg MS, Fleming SM, Palacino JJ, et al. Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J Biol Chem 2003;278:43628-43635
-
(2003)
J Biol Chem
, vol.278
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
-
41
-
-
30744443484
-
Dopamine covalently modifies and functionally inactivates parkin
-
laVoie MJ, Ostaszewski Bl, Weihofen A, et al. Dopamine covalently modifies and functionally inactivates parkin. Nat Med 2005;11:1214-1221
-
(2005)
Nat Med
, vol.11
, pp. 1214-1221
-
-
Lavoie, M.J.1
Bl, O.2
Weihofen, A.3
-
42
-
-
20444401187
-
Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations
-
Norris EH, Giasson BI, Hodara R, et al. Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations. J Biol Chem 2005;280:21212-21219
-
(2005)
J Biol Chem
, vol.280
, pp. 21212-21219
-
-
Norris, E.H.1
Giasson, B.I.2
Hodara, R.3
-
43
-
-
33749170166
-
Cytosolic catechols inhibit ?-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates
-
Mazzulli JR, Mishizen AJ, Giasson BI, et al. Cytosolic catechols inhibit ?-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates. J Neurosci 2006;26:10068-10078
-
(2006)
J Neurosci
, vol.26
, pp. 10068-10078
-
-
Mazzulli, J.R.1
Mishizen, A.J.2
Giasson, B.I.3
-
44
-
-
33845643466
-
Alpha-synuclein induces hyperphosphorylation of Tau in the MPTP model of parkinsonism
-
Duka T, Rusnak M, Drolet RE, et al. Alpha-synuclein induces hyperphosphorylation of Tau in the MPTP model of parkinsonism. FASEB J 2006;20:2302-2312
-
(2006)
FASEB J
, vol.20
, pp. 2302-2312
-
-
Duka, T.1
Rusnak, M.2
Drolet, R.E.3
-
45
-
-
0038456964
-
Nuclear localization of alpha-synuclein and its interactionwith histones
-
Goers J, Manning-Bog AB, McCormack Al, et al. Nuclear localization of alpha-synuclein and its interactionwith histones. Biochemistry 2003;42:8465-8471
-
(2003)
Biochemistry
, vol.42
, pp. 8465-8471
-
-
Goers, J.1
Manning-Bog, A.B.2
Al, M.3
-
46
-
-
70349331692
-
-Synuclein contributes to GSK-3{beta}-catalyzed Tau phosphorylation in Parkinson's disease models
-
press
-
Duka T, Duka V, Joyce JN, Sidhu A. {alpha}-Synuclein contributes to GSK-3{beta}-catalyzed Tau phosphorylation in Parkinson's disease models. FASEB J 2009. In press
-
(2009)
FASEB J
-
-
Duka, T.1
Duka, V.2
Joyce, J.N.3
-
47
-
-
65249180086
-
Interplay between cytosolic dopamine, calcium, and a-synuclein causes selective death of substantia nigra neurons
-
Mosharov EV, larsen KE, Kanter E, et al. Interplay between cytosolic dopamine, calcium, and a-synuclein causes selective death of substantia nigra neurons. Neuron 2009;62:218-229
-
(2009)
Neuron
, vol.62
, pp. 218-229
-
-
Mosharov, E.V.1
Larsen, K.E.2
Kanter, E.3
-
48
-
-
38849174979
-
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy
-
Martinez-Vicente M, Talloczy Z, Kaushik S, et al. Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. J Clin Invest 2008;118:777-788
-
(2008)
J Clin Invest
, vol.118
, pp. 777-788
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Kaushik, S.3
-
49
-
-
38149073317
-
Aggregation of alpha-synuclein by DOPAl, the monoamine oxidase metabolite of dopamine
-
Burke WJ, Kumar VB, Pandey N, et al. Aggregation of alpha-synuclein by DOPAl, the monoamine oxidase metabolite of dopamine. Acta Neuropathol 2008;115:193-203
-
(2008)
Acta Neuropathol
, vol.115
, pp. 193-203
-
-
Burke, W.J.1
Kumar, V.B.2
Pandey, N.3
-
50
-
-
0025869874
-
Temporal relationships between plasma and cerebrospinal fluid pharmacokinetics of levodopa and clinical effect in Parkinson's disease
-
Olanow CW, Gauger ll, Cedarbaum JM. Temporal relationships between plasma and cerebrospinal fluid pharmacokinetics of levodopa and clinical effect in Parkinson's disease. Ann Neurol 1991;29:556-559
-
(1991)
Ann Neurol
, vol.29
, pp. 556-559
-
-
Olanow, C.W.1
Gauger, L.L.2
Cedarbaum, J.M.3
-
51
-
-
26444597591
-
And the Parkinson study group. Does levodopa slow or hasten the rate of progression of Parkinson's disease?
-
Fahn S, and the Parkinson study group. Does levodopa slow or hasten the rate of progression of Parkinson's disease? J Neurol 2005;252(Suppl 4):IV37-42
-
(2005)
J Neurol
, vol.252
, Issue.SUPPL. 4
-
-
Fahn, S.1
-
52
-
-
33947105151
-
Levodopa slows progression of Parkinson's disease. External validation by clinical trial simulation
-
Chan Pl, Nutt JG, Holford NH. levodopa slows progression of Parkinson's disease. External validation by clinical trial simulation. Pharm Res 2007;24:791-802
-
(2007)
Pharm Res
, vol.24
, pp. 791-802
-
-
Pl, C.1
Nutt, J.G.2
Holford, N.H.3
-
53
-
-
0035293569
-
Gene therapy for Parkinson's disease: Determining the genes necessary for optimal dopamine replacement in rat models
-
Kang UJ, lee WY, Chang JW. Gene therapy for Parkinson's disease: determining the genes necessary for optimal dopamine replacement in rat models. Hum Cell 2001;14:39-48
-
(2001)
Hum Cell
, vol.14
, pp. 39-48
-
-
Kang, U.J.1
Lee, W.Y.2
Chang, J.W.3
-
54
-
-
0742272695
-
Low-level tyrosine hydroxylase (TH) expression allows for the generation of stable TH+ cell lines of human neural stem cells
-
liste I, Navarro B, Johansen J, et al. low-level tyrosine hydroxylase (TH) expression allows for the generation of stable TH+ cell lines of human neural stem cells. Hum Gene Ther 2004;15:13-20
-
(2004)
Hum Gene Ther
, vol.15
, pp. 13-20
-
-
Liste, I.1
Navarro, B.2
Johansen, J.3
-
55
-
-
34347359673
-
Rejuvenation' protects neurons in mouse models of Parkinson's disease
-
Chan CS, Guzman JN, Ilijic E, et al. 'Rejuvenation' protects neurons in mouse models of Parkinson's disease. Nature 2007;447:1081-1086
-
(2007)
Nature
, vol.447
, pp. 1081-1086
-
-
Chan, C.S.1
Guzman, J.N.2
Ilijic, E.3
-
57
-
-
18144406539
-
Oxidative stress and inflammation in Parkinson's disease: Is there a causal link?
-
Hald A, lotharius J. Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Exp Neurol 2005;193:279-290
-
(2005)
Exp Neurol
, vol.193
, pp. 279-290
-
-
Hald, A.1
Lotharius, J.2
-
58
-
-
0034043595
-
Neuroprotective strategies in Parkinson's disease using the models of 6-hydroxydopamine and MPTP
-
Grunblatt E, Mandel S, Youdim MB. Neuroprotective strategies in Parkinson's disease using the models of 6-hydroxydopamine and MPTP. Ann NY Acad Sci 2000;899:262-273 (Pubitemid 30352792)
-
(2000)
Annals of the New York Academy of Sciences
, vol.899
, pp. 262-273
-
-
Grunblatt, E.1
Mandel, S.2
Youdim, M.B.H.3
-
59
-
-
0345724066
-
Dopamine turnover and glutathione oxidation: Implications for Parkinson disease
-
Spina MB, Cohen G. Dopamine turnover and glutathione oxidation: implications for Parkinson disease. Proc Natl Acad Sci USA 1989;86:1398-1400
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 1398-1400
-
-
Spina, M.B.1
Cohen, G.2
-
60
-
-
0027344487
-
Degeneration of dopaminergic neurons and free radicals. Possible participation of levodopa
-
Ogawa N, Edamatsu R, Mizukawa K, et al. Degeneration of dopaminergic neurons and free radicals. Possible participation of levodopa. Adv Neurol 1993;60:242-250
-
(1993)
Adv Neurol
, vol.60
, pp. 242-250
-
-
Ogawa, N.1
Edamatsu, R.2
Mizukawa, K.3
-
61
-
-
50949117770
-
Dopaminergic neuron-specific oxidative stress caused by dopamine itself
-
Miyazaki I, Asanuma M. Dopaminergic neuron-specific oxidative stress caused by dopamine itself. Acta Med Okayama 2008;62:141-150
-
(2008)
Acta Med Okayama
, vol.62
, pp. 141-150
-
-
Miyazaki, I.1
Asanuma, M.2
-
62
-
-
0014209801
-
Electrochemical studies of the oxidation pathways of catecholamines
-
Hawley MD, Tatawawadi SV, Piekarski S, et al. Electrochemical studies of the oxidation pathways of catecholamines. J Am Chem Soc 1967;89:447-450
-
(1967)
J Am Chem Soc
, vol.89
, pp. 447-450
-
-
Hawley, M.D.1
Tatawawadi, S.V.2
Piekarski, S.3
-
63
-
-
0028965835
-
Superoxide dismutase and catalase enhance autoxidation during one-electron reduction of aminochrome by NADPH-cytochrome P-450 reductase
-
Baez S, linderson Y, Segura-Aguilar J. Superoxide dismutase and catalase enhance autoxidation during one-electron reduction of aminochrome by NADPH-cytochrome P-450 reductase. Biochem Mol Med 1995;54:12-18
-
(1995)
Biochem Mol Med
, vol.54
, pp. 12-18
-
-
Baez, S.1
Linderson, Y.2
Segura-Aguilar, J.3
-
64
-
-
0032486311
-
Metabolic activation of dopamine o-quinones to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects
-
Segura-Aguilar J, Metodiewa D, Welch CJ. Metabolic activation of dopamine o-quinones to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects. Biochim Biophys Acta 1998;1381:1-6
-
(1998)
Biochim Biophys Acta
, vol.1381
, pp. 1-6
-
-
Segura-Aguilar, J.1
Metodiewa, D.2
Welch, C.J.3
-
65
-
-
34249794888
-
Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: The role of aldehyde dehydrogenase
-
Marchitti SA, Deitrich RA, Vasiliou V. Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase. Pharmacol Rev 2007;59:125-150
-
(2007)
Pharmacol Rev
, vol.59
, pp. 125-150
-
-
Marchitti, S.A.1
Deitrich, R.A.2
Vasiliou, V.3
-
66
-
-
4644328053
-
The effect of monoamine oxidase B (MAOB) and catechol-O-methyltransferase (COMT) polymorphisms on levoDOPA therapy in patients with sporadic Parkinson's disease
-
Bialecka M, Drozdzik M, Klodowska-Duda G, et al. The effect of monoamine oxidase B (MAOB) and catechol-O-methyltransferase (COMT) polymorphisms on levoDOPA therapy in patients with sporadic Parkinson's disease. Acta Neurol Scand 2004;110:260-266
-
(2004)
Acta Neurol Scand
, vol.110
, pp. 260-266
-
-
Bialecka, M.1
Drozdzik, M.2
Klodowska-Duda, G.3
-
67
-
-
0027487511
-
Chronic levoDOPA administration alters cerebral mitochondrial respiratory chain activity
-
Przedborski S, Jackson-lewis V, Muthane U, et al. Chronic levoDOPA administration alters cerebral mitochondrial respiratory chain activity. Ann Neurol 1993;34:715-723
-
(1993)
Ann Neurol
, vol.34
, pp. 715-723
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Muthane, U.3
-
68
-
-
0028081018
-
Intense oxidative DNA damage promoted by l-DOPA and its metabolites. Implications for neurodegenerative disease
-
Spencer JP, Jenner A, Aruoma OI, et al. Intense oxidative DNA damage promoted by l-DOPA and its metabolites. Implications for neurodegenerative disease. FEBS lett 1994;353:246-250
-
(1994)
FEBS Lett
, vol.353
, pp. 246-250
-
-
Spencer, J.P.1
Jenner, A.2
Aruoma, O.I.3
-
69
-
-
0024340065
-
Levodopa/dopamine analogs as inhibitors of DNA synthesis in human melanoma cells
-
Wick MM. levodopa/dopamine analogs as inhibitors of DNA synthesis in human melanoma cells. J Invest Dermatol 1989;92:329S-31S
-
(1989)
J Invest Dermatol
, vol.92
-
-
Wick, M.M.1
-
70
-
-
0036116903
-
LevoDOPA pharmacokinetics and motor performance during activities of daily living in patients with Parkinson's disease on individual drug combinations
-
Nyholm D, lennernas H, Gomes-Trolin C, et al. levoDOPA pharmacokinetics and motor performance during activities of daily living in patients with Parkinson's disease on individual drug combinations. Clin Neuropharmacol 2002;25:89-96
-
(2002)
Clin Neuropharmacol
, vol.25
, pp. 89-96
-
-
Nyholm, D.1
Lennernas, H.2
Gomes-Trolin, C.3
-
71
-
-
0026353474
-
CDNA cloning and properties of glycogen synthase kinase-3
-
Woodgett cDNA cloning and properties of glycogen synthase kinase-3. Methods Enzymol 1991;200:564-577
-
(1991)
Methods Enzymol
, vol.200
, pp. 564-577
-
-
Woodgett, J.R.1
-
72
-
-
23244436178
-
Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene
-
Koh SH, lee YB, Kim KS, et al. Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene. Eur J Neurosci 2005;22:301-309
-
(2005)
Eur J Neurosci
, vol.22
, pp. 301-309
-
-
Koh, S.H.1
Lee, Y.B.2
Kim, K.S.3
-
73
-
-
23944442778
-
Phosphatidylinositol 3-kinase activator reduces motor neuronal cell death induced by G93A or A4V mutant SOD1 gene
-
Koh SH, Roh H, lee SM, et al. Phosphatidylinositol 3-kinase activator reduces motor neuronal cell death induced by G93A or A4V mutant SOD1 gene. Toxicology 2005;213:45-55
-
(2005)
Toxicology
, vol.213
, pp. 45-55
-
-
Koh, S.H.1
Roh, H.2
Lee, S.M.3
-
74
-
-
0032493729
-
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway
-
Pap M, Cooper GM. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway. J Biol Chem 1998;273:19929-19932
-
(1998)
J Biol Chem
, vol.273
, pp. 19929-19932
-
-
Pap, M.1
Cooper, G.M.2
-
75
-
-
0036136897
-
Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway
-
Pap M, Cooper GM. Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway. Mol Cell Biol 2002;22:578-586
-
(2002)
Mol Cell Biol
, vol.22
, pp. 578-586
-
-
Pap, M.1
Cooper, G.M.2
-
76
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley lC. The phosphoinositide 3-kinase pathway. Science 2002;296:1655-1657
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Lc, C.1
-
77
-
-
0032518695
-
Signal transduction by the Wnt family of ligands
-
Dale TC. Signal transduction by the Wnt family of ligands. Biochem J 1998;329(Pt 2):209-223
-
(1998)
Biochem J
, vol.329
, Issue.PART 2
, pp. 209-223
-
-
Dale, T.C.1
-
78
-
-
0036860704
-
The Wnt signalling pathway
-
Huelsken J, Behrens J. The Wnt signalling pathway. J Cell Sci 2002;115:3977-3978
-
(2002)
J Cell Sci
, vol.115
, pp. 3977-3978
-
-
Huelsken, J.1
Behrens, J.2
-
79
-
-
0035903090
-
Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels
-
Kirschenbaum F, Hsu SC, Cordell B, et al. Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels. J Biol Chem 2001;276:30701-30707
-
(2001)
J Biol Chem
, vol.276
, pp. 30701-30707
-
-
Kirschenbaum, F.1
Hsu, S.C.2
Cordell, B.3
-
80
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
Phiel CJ, Wilson CA, lee VM, et al. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 2003;423:435-439
-
(2003)
Nature
, vol.423
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.3
-
81
-
-
3142512452
-
Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration
-
Koo EH, Kopan R. Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration. Nat Med 2004;10(Suppl):S26-33
-
(2004)
Nat Med
, vol.10
, Issue.SUPPL.
-
-
Koo, E.H.1
Kopan, R.2
-
82
-
-
0345184327
-
Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord
-
Hu JH, Zhang H, Wagey R, et al. Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord. J Neurochem 2003;85:432-442
-
(2003)
J Neurochem
, vol.85
, pp. 432-442
-
-
Hu, J.H.1
Zhang, H.2
Wagey, R.3
-
83
-
-
10844284615
-
Benefit of valproic acid in suppressing disease progression of AlS model mice
-
Sugai F, Yamamoto Y, Miyaguchi K, et al. Benefit of valproic acid in suppressing disease progression of AlS model mice. Eur J Neurosci 2004;20:3179-3183
-
(2004)
Eur J Neurosci
, vol.20
, pp. 3179-3183
-
-
Sugai, F.1
Yamamoto, Y.2
Miyaguchi, K.3
-
84
-
-
33751331389
-
Activation of the Akt/GSK3beta signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats
-
Endo H, Nito C, Kamada H, et al. Activation of the Akt/GSK3beta signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats. J Cereb Blood Flow Metab 2006;26:1479-1489
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 1479-1489
-
-
Endo, H.1
Nito, C.2
Kamada, H.3
-
85
-
-
44149110850
-
Inhibition of GSK-3 reduces infarct volume and improves neurobehavioral functions
-
Koh SH, Yoo AR, Chang DI, et al. Inhibition of GSK-3 reduces infarct volume and improves neurobehavioral functions. Biochem Biophys Res Commun 2008;371:894-899
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 894-899
-
-
Koh, S.H.1
Yoo, A.R.2
Chang, D.I.3
-
86
-
-
34247585007
-
Pharmacological modulation of stem cell function
-
Romagnani P, lasagni l, Mazzinghi B, et al. Pharmacological modulation of stem cell function. Curr Med Chem 2007;14:1129-1139
-
(2007)
Curr Med Chem
, vol.14
, pp. 1129-1139
-
-
Romagnani, P.1
Lasagni, L.2
Mazzinghi, B.3
-
87
-
-
0037160134
-
Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation
-
Song l, De Sarno P, Jope RS. Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation. J Biol Chem 2002;277:44701-44708
-
(2002)
J Biol Chem
, vol.277
, pp. 44701-44708
-
-
Song, L.1
De Sarno, P.2
Jope, R.S.3
-
88
-
-
33845643466
-
Alpha-synuclein induces hyperphosphorylation of Tau in the MPTP model of parkinsonism
-
Duka T, Rusnak M, Drolet RE, et al. Alpha-synuclein induces hyperphosphorylation of Tau in the MPTP model of parkinsonism. FASEB J 2006;20:2302-2312
-
(2006)
FASEB J
, vol.20
, pp. 2302-2312
-
-
Duka, T.1
Rusnak, M.2
Drolet, R.E.3
-
89
-
-
33845989064
-
Glycogen synthase kinase-3beta activity plays very important roles in determining the fate of oxidative stress-inflicted neuronal cells
-
lee KY, Koh SH, Noh MY, et al. Glycogen synthase kinase-3beta activity plays very important roles in determining the fate of oxidative stress-inflicted neuronal cells. Brain Res 2007;1129:89-99
-
(2007)
Brain Res
, vol.1129
, pp. 89-99
-
-
Lee, K.Y.1
Koh, S.H.2
Noh, M.Y.3
|