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Volumn 252, Issue SUPPL. 4, 2005, Pages

Levodopa therapy from the neuroprotection viewpoint: From a clinical outlook

Author keywords

Dopamine; Free radicals; Levodopa; Neuroprotection; Parkinson's disease

Indexed keywords

DOPAMINE RECEPTOR STIMULATING AGENT; FREE RADICAL; LEVODOPA;

EID: 26644437449     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-005-4007-6     Document Type: Conference Paper
Times cited : (12)

References (37)
  • 1
    • 0021165054 scopus 로고
    • Oxy-radical toxicity in catecholamine neurons
    • Cohen G (1984) Oxy-radical toxicity in catecholamine neurons. Neurotoxicology 5(1):77-82
    • (1984) Neurotoxicology , vol.5 , Issue.1 , pp. 77-82
    • Cohen, G.1
  • 2
    • 0141638380 scopus 로고    scopus 로고
    • 3.4-Dihydroxyphenylacetaldehyde is the toxic dopamine metabolite in vivo: Implications for Parkinson's disease pathogenesis
    • Burke WJ, Li SW, Williams EA, Nonneman R, Zahm DS (2003) 3.4-Dihydroxyphenylacetaldehyde is the toxic dopamine metabolite in vivo: implications for Parkinson's disease pathogenesis. Brain Res 989(2):205-213
    • (2003) Brain Res , vol.989 , Issue.2 , pp. 205-213
    • Burke, W.J.1    Li, S.W.2    Williams, E.A.3    Nonneman, R.4    Zahm, D.S.5
  • 4
    • 0034899258 scopus 로고    scopus 로고
    • Levodopa prolongs life expectancy and is non-toxic to substantia nigra
    • Rajput AH (2001) Levodopa prolongs life expectancy and is non-toxic to substantia nigra. Parkinsonism Relat Disord 8(2):95-100
    • (2001) Parkinsonism Relat Disord , vol.8 , Issue.2 , pp. 95-100
    • Rajput, A.H.1
  • 5
    • 0037012478 scopus 로고    scopus 로고
    • Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression
    • Parkinson Study Group (2002) Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression. JAMA 287(13):1653-1661
    • (2002) JAMA , vol.287 , Issue.13 , pp. 1653-1661
  • 8
    • 0031017290 scopus 로고    scopus 로고
    • Generation of reactive oxygen species by tyrosine hydroxylase: A possible contribution to the degeneration of dopaminergic neurons?
    • Haavik J, Almas B, Flatmark T (1997) Generation of reactive oxygen species by tyrosine hydroxylase: a possible contribution to the degeneration of dopaminergic neurons? J Neurochem 68(1):328-332
    • (1997) J Neurochem , vol.68 , Issue.1 , pp. 328-332
    • Haavik, J.1    Almas, B.2    Flatmark, T.3
  • 9
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • Jenner P (2003) Oxidative stress in Parkinson's disease. Ann Neurol 53 (Suppl 3):S26-S36
    • (2003) Ann Neurol , vol.53 , Issue.3 SUPPL.
    • Jenner, P.1
  • 10
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn S, Cohen G (1992) The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol 32(6):804-812
    • (1992) Ann Neurol , vol.32 , Issue.6 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 11
    • 0031776914 scopus 로고    scopus 로고
    • Toxicity of dopamine to striatal neurons in vitro and potentiation of cell death by a mitochondrial inhibitor
    • McLaughlin BA, Nelson D, Erecinska M, Chesselet MF (1998) Toxicity of dopamine to striatal neurons in vitro and potentiation of cell death by a mitochondrial inhibitor. J Neurochem 70(6):2406-2415
    • (1998) J Neurochem , vol.70 , Issue.6 , pp. 2406-2415
    • McLaughlin, B.A.1    Nelson, D.2    Erecinska, M.3    Chesselet, M.F.4
  • 12
    • 0030059868 scopus 로고    scopus 로고
    • L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress
    • Han SK, Mytilineou C, Cohen G (1996) L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. J Neurochem 66(2):501-510
    • (1996) J Neurochem , vol.66 , Issue.2 , pp. 501-510
    • Han, S.K.1    Mytilineou, C.2    Cohen, G.3
  • 13
    • 0037309436 scopus 로고    scopus 로고
    • Levodopa is toxic to dopamine neurons in an in vitro but not an in vivo model of oxidative stress
    • Mytilineou C, Walker RH, JnoBaptiste R, Olanow CW (2003) Levodopa is toxic to dopamine neurons in an in vitro but not an in vivo model of oxidative stress. J Pharmacol Exp Ther 304(2):792-800
    • (2003) J Pharmacol Exp Ther , vol.304 , Issue.2 , pp. 792-800
    • Mytilineou, C.1    Walker, R.H.2    JnoBaptiste, R.3    Olanow, C.W.4
  • 14
    • 0022946382 scopus 로고
    • Preservation of the substantia nigra and locus coeruleus in a patient receiving levodopa (2 kg) plus decarboxylase inhibitor over a four-year period
    • Quinn N, Parkes D, Janota I, Marsden CD (1986) Preservation of the substantia nigra and locus coeruleus in a patient receiving levodopa (2 kg) plus decarboxylase inhibitor over a four-year period. Mov Disord 1(1):65-68
    • (1986) Mov Disord , vol.1 , Issue.1 , pp. 65-68
    • Quinn, N.1    Parkes, D.2    Janota, I.3    Marsden, C.D.4
  • 15
    • 0034899258 scopus 로고    scopus 로고
    • Levodopa prolongs life expectancy and is non-toxic to substantia nigra
    • Rajput AH (2001) Levodopa prolongs life expectancy and is non-toxic to substantia nigra. Parkinsonism Relat Disord 8(2):95-100
    • (2001) Parkinsonism Relat Disord , vol.8 , Issue.2 , pp. 95-100
    • Rajput, A.H.1
  • 16
    • 0028343897 scopus 로고
    • Differential effects of chronic L-dopa treatment on lipid peroxidation in the mouse brain with or without pretreatment with 6-hydroxydopamine
    • Ogawa N, Asanuma M, Kondo Y, Kawada Y, Yamamoto M, Mori A (1994) Differential effects of chronic L-dopa treatment on lipid peroxidation in the mouse brain with or without pretreatment with 6-hydroxydopamine. Neurosci Lett 25; 171(1-2):55-58
    • (1994) Neurosci Lett , vol.171 , Issue.1-2 , pp. 55-58
    • Ogawa, N.1    Asanuma, M.2    Kondo, Y.3    Kawada, Y.4    Yamamoto, M.5    Mori, A.6
  • 17
    • 0031968959 scopus 로고    scopus 로고
    • Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions
    • Murer MG, Dziewczapolski G, Menalled LB, Garcia MC, Agid Y, Gershanik O, Raisman-Vozari R (1998) Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions. Ann Neurol 43(5):561-575
    • (1998) Ann Neurol , vol.43 , Issue.5 , pp. 561-575
    • Murer, M.G.1    Dziewczapolski, G.2    Menalled, L.B.3    Garcia, M.C.4    Agid, Y.5    Gershanik, O.6    Raisman-Vozari, R.7
  • 18
    • 0034973443 scopus 로고    scopus 로고
    • An algorithm (decision tree) for the management of Parkinson's disease (2001): Treatment guidelines
    • Olanow CW, Watts RL, Koller WC (2001) An algorithm (decision tree) for the management of Parkinson's disease (2001): treatment guidelines. Neurology 56(11 Suppl 5):S1-S88
    • (2001) Neurology , vol.56 , Issue.11 SUPPL. 5
    • Olanow, C.W.1    Watts, R.L.2    Koller, W.C.3
  • 20
    • 0032774493 scopus 로고    scopus 로고
    • Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cells
    • Coldwell MC, Boyfield I, Brown T, Hagan JJ, Middlemiss DN (1999) Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 127(7):1696-1702
    • (1999) Br J Pharmacol , vol.127 , Issue.7 , pp. 1696-1702
    • Coldwell, M.C.1    Boyfield, I.2    Brown, T.3    Hagan, J.J.4    Middlemiss, D.N.5
  • 21
    • 1542327580 scopus 로고    scopus 로고
    • Dopamine agonists, receptor selectivity and dyskinesia induction in Parkinson's disease
    • Jenner P (2003) Dopamine agonists, receptor selectivity and dyskinesia induction in Parkinson's disease. Curr Opin Neurol 16(Suppl 1):S3-S7
    • (2003) Curr Opin Neurol , vol.16 , Issue.1 SUPPL.
    • Jenner, P.1
  • 22
    • 0026511969 scopus 로고
    • The natural history of Parkinson's disease in the pre-levodopa and post-levodopa eras
    • Hoehn MM (1992) The natural history of Parkinson's disease in the pre-levodopa and post-levodopa eras. Neurol Clin 10(2):331-339
    • (1992) Neurol Clin , vol.10 , Issue.2 , pp. 331-339
    • Hoehn, M.M.1
  • 23
    • 0034682308 scopus 로고    scopus 로고
    • A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa
    • 056 Study Group
    • Rascol O, Brooks DJ, Korczyn AD, De Deyn PP, Clarke CE, Lang AE (2000) A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. 056 Study Group. N Engl J Med 342(20):1484-1491
    • (2000) N Engl J Med , vol.342 , Issue.20 , pp. 1484-1491
    • Rascol, O.1    Brooks, D.J.2    Korczyn, A.D.3    De Deyn, P.P.4    Clarke, C.E.5    Lang, A.E.6
  • 24
    • 0031927090 scopus 로고    scopus 로고
    • Dopamine D2-type agonists protect mesencephalic neurons from glutamate neurotoxicity: Mechanisms of neuroprotective treatment against oxidative stress
    • Sawada H, Ibi M, Kihara T, Urushitani M, Akaike A, Kimura J, Shimohama S (1998) Dopamine D2-type agonists protect mesencephalic neurons from glutamate neurotoxicity: mechanisms of neuroprotective treatment against oxidative stress. Ann Neurol 44(1):110-119
    • (1998) Ann Neurol , vol.44 , Issue.1 , pp. 110-119
    • Sawada, H.1    Ibi, M.2    Kihara, T.3    Urushitani, M.4    Akaike, A.5    Kimura, J.6    Shimohama, S.7
  • 25
    • 0032424146 scopus 로고    scopus 로고
    • Dopamine D1 and D2 receptor-mediated acute and long-lasting behavioral effects of glial cell line-derived neurotrophic factor administered into the striatum
    • Kobayashi S, Ogren SO, Hoffer BJ, Olson L (1998) Dopamine D1 and D2 receptor-mediated acute and long-lasting behavioral effects of glial cell line-derived neurotrophic factor administered into the striatum. Exp Neurol 154(2):302-314
    • (1998) Exp Neurol , vol.154 , Issue.2 , pp. 302-314
    • Kobayashi, S.1    Ogren, S.O.2    Hoffer, B.J.3    Olson, L.4
  • 26
    • 2642520236 scopus 로고    scopus 로고
    • Cabergoline stimulates synthesis and secretion of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor by mouse astrocytes in primary culture
    • Ohta K, Fujinami A, Kuno S, Sakakimoto A, Matsui H, Kawahara Y, Ohta M (2004) Cabergoline stimulates synthesis and secretion of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor by mouse astrocytes in primary culture. Pharmacology 71(3):162-168
    • (2004) Pharmacology , vol.71 , Issue.3 , pp. 162-168
    • Ohta, K.1    Fujinami, A.2    Kuno, S.3    Sakakimoto, A.4    Matsui, H.5    Kawahara, Y.6    Ohta, M.7
  • 27
    • 0036835002 scopus 로고    scopus 로고
    • Apomorphine induces trophic factors that support fetal rat mesencephalic dopaminergic neurons in cultures
    • Guo H, Tang Z, Yu Y, Xu L, Jin G, Zhou J (2002) Apomorphine induces trophic factors that support fetal rat mesencephalic dopaminergic neurons in cultures. Eur J Neurosci 16(10):1861-1870
    • (2002) Eur J Neurosci , vol.16 , Issue.10 , pp. 1861-1870
    • Guo, H.1    Tang, Z.2    Yu, Y.3    Xu, L.4    Jin, G.5    Zhou, J.6
  • 28
    • 0034668920 scopus 로고    scopus 로고
    • Neuroprotective role of dopamine against hippocampal cell death
    • Bozzi Y, Vallone D, Borrelli E (2000) Neuroprotective role of dopamine against hippocampal cell death. J Neurosci 20(22):8643-8649
    • (2000) J Neurosci , vol.20 , Issue.22 , pp. 8643-8649
    • Bozzi, Y.1    Vallone, D.2    Borrelli, E.3
  • 29
    • 0037355762 scopus 로고    scopus 로고
    • D2 Dopamine receptor blockade results in sprouting of DA axons in the intact animal but prevents sprouting following nigral lesions
    • Tripanichkul W, Stanic D, Drago J, Finkelstein DI, Horne MK (2003) D2 Dopamine receptor blockade results in sprouting of DA axons in the intact animal but prevents sprouting following nigral lesions. Eur J Neurosci 17(5):1033-1045
    • (2003) Eur J Neurosci , vol.17 , Issue.5 , pp. 1033-1045
    • Tripanichkul, W.1    Stanic, D.2    Drago, J.3    Finkelstein, D.I.4    Horne, M.K.5
  • 30
    • 0026486342 scopus 로고
    • Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum
    • Okazawa H, Murata M, Watanabe M, Kamei M, Kanazawa I (1992) Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum. FEBS Lett 313(2):138-142
    • (1992) FEBS Lett , vol.313 , Issue.2 , pp. 138-142
    • Okazawa, H.1    Murata, M.2    Watanabe, M.3    Kamei, M.4    Kanazawa, I.5
  • 33
    • 3242675431 scopus 로고    scopus 로고
    • Voluntary running provides neuroprotection in rats after 6-hydroxydopamine injection into the medial forebrain bundle
    • Mabandla M, Kellaway L, St Clair Gibson A, Russell VA (2004) Voluntary running provides neuroprotection in rats after 6-hydroxydopamine injection into the medial forebrain bundle. Metab Brain Dis 19:43-50
    • (2004) Metab Brain Dis , vol.19 , pp. 43-50
    • Mabandla, M.1    Kellaway, L.2    St Clair Gibson, A.3    Russell, V.A.4
  • 34
    • 0344394948 scopus 로고    scopus 로고
    • Can the brain be protected through exercise? Lessons from an animal model of parkinsonism
    • Smith AD, Zigmond MJ (2003) Can the brain be protected through exercise? Lessons from an animal model of parkinsonism. Exp Neurol 184:31-39
    • (2003) Exp Neurol , vol.184 , pp. 31-39
    • Smith, A.D.1    Zigmond, M.J.2
  • 35
    • 0012849885 scopus 로고    scopus 로고
    • Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease
    • Tillerson JL, Caudle WM, Reveron ME, Miller GW (2003) Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease. Neuroscience 119:899-911
    • (2003) Neuroscience , vol.119 , pp. 899-911
    • Tillerson, J.L.1    Caudle, W.M.2    Reveron, M.E.3    Miller, G.W.4
  • 36
    • 0345669747 scopus 로고    scopus 로고
    • Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: Possible role of GDNF
    • Cohen AD, Tillerson JL, Smith AD, Schallert T, Zigmond MJ (2003) Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF. J Neurochem 85:299-305
    • (2003) J Neurochem , vol.85 , pp. 299-305
    • Cohen, A.D.1    Tillerson, J.L.2    Smith, A.D.3    Schallert, T.4    Zigmond, M.J.5
  • 37
    • 3242795769 scopus 로고    scopus 로고
    • Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia
    • Fisher BE, Petzinger GM, Nixon K, Hogg E, Bremmer S, Meshul CK, Jakowec MW (2005) Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia. J Neurosci Res 77:378-390
    • (2005) J Neurosci Res , vol.77 , pp. 378-390
    • Fisher, B.E.1    Petzinger, G.M.2    Nixon, K.3    Hogg, E.4    Bremmer, S.5    Meshul, C.K.6    Jakowec, M.W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.