Metabolic activation of dopamine o-quinones to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects

Biochimica et Biophysica Acta - General Subjects

Volumn 1381, Issue 1, 1998, Pages 1-6

  Segura Aguilar, Juan ^a   Metodiewa, Diana ^b   Welch, Christopher J ^c  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Cytotoxicity; Dopamine; Lactoperoxidase; NADPH cytochrome P450 reductase; Oxidation; Quinone; Reduction; Semiquinone; Tyrosinase

Indexed keywords

DOPAMINE; MONOPHENOL MONOOXYGENASE; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; SEMIQUINONE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CYTOTOXICITY; DRUG OXIDATION; METABOLIC ACTIVATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BIOTRANSFORMATION; CHO CELLS; CRICETINAE; DOPAMINE; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATIVE STRESS;

EID: 0032486311     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4165(98)00036-1     Document Type: Article

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