-
1
-
-
17644379373
-
Caspase-3-dependent β-cell apoptosis in the initiation of autoimmune diabetes mellitus
-
DOI 10.1128/MCB.25.9.3620-3629.2005
-
Liadis N, Murakami K, Eweida M, Elford AR, Sheu L, Gaisano HY, Hakem R, Ohashi PS, Woo M. Caspase-3-dependent β-cell apoptosis in the initiation of autoimmune diabetes mellitus. Mol Cell Biol 2005;25:3620-3629 (Pubitemid 40559568)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.9
, pp. 3620-3629
-
-
Liadis, N.1
Murakami, K.2
Eweida, M.3
Elford, A.R.4
Sheu, L.5
Gaisano, H.Y.6
Hakem, R.7
Ohashi, P.S.8
Woo, M.9
-
2
-
-
20444363538
-
Beta-cells in type 2 diabetes: A loss of function and mass
-
Maedler K, Donath MY. Beta-cells in type 2 diabetes: a loss of function and mass. Horm Res 2004;62(Suppl. 3):67-73
-
(2004)
Horm Res
, vol.62
, Issue.SUPPL. 3
, pp. 67-73
-
-
Maedler, K.1
Donath, M.Y.2
-
3
-
-
1842844414
-
Decreased beta-cell mass in diabetes: Significance, mechanisms and therapeutic implications
-
Donath MY, Halban PA. Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications. Diabetologia 2004;47:581-589
-
(2004)
Diabetologia
, vol.47
, pp. 581-589
-
-
Donath, M.Y.1
Halban, P.A.2
-
5
-
-
28444491105
-
Mechanisms of apoptosis through structural biology
-
Yan N, Shi Y. Mechanisms of apoptosis through structural biology. Annu Rev Cell Dev Biol 2005;21:35-56
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 35-56
-
-
Yan, N.1
Shi, Y.2
-
6
-
-
33644747390
-
Mechanisms of β-cell death in type 2 diabetes
-
DOI 10.2337/diabetes.54.suppl-2.S108
-
Donath MY, Ehses JA, Maedler K, Schumann DM, Ellingsgaard H, Eppler E, Reinecke M. Mechanisms of β-cell death in type 2 diabetes. Diabetes 2005;54(Suppl. 2):S108-S113 (Pubitemid 43343338)
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Donath, M.Y.1
Ehses, J.A.2
Maedler, K.3
Schumann, D.M.4
Ellingsgaard, H.5
Eppler, E.6
Reinecke, M.7
-
7
-
-
0036584585
-
Apoptosis in hypoxic human pancreatic islets correlates with HIF-1α expression
-
Moritz W, Meier F, Stroka DM, Giuliani M, Kugelmeier P, Nett PC, Lehmann R, Candinas D, Gassmann M, Weber M. Apoptosis in hypoxic human pancreatic islets correlates with HIF-1α expression. FASEB J 2002;16:745-747
-
(2002)
FASEB J
, vol.16
, pp. 745-747
-
-
Moritz, W.1
Meier, F.2
Stroka, D.M.3
Giuliani, M.4
Kugelmeier, P.5
Nett, P.C.6
Lehmann, R.7
Candinas, D.8
Gassmann, M.9
Weber, M.10
-
8
-
-
0033039383
-
Pancreatic islet cell survival following islet isolation: The role of cellular interactions in the pancreas
-
DOI 10.1677/joe.0.1610357
-
Ilieva A, Yuan S, Wang RN, Agapitos D, Hill DJ, Rosenberg L. Pancreatic islet cell survival following islet isolation: the role of cellular interactions in the pancreas. J Endocrinol 1999;161:357-364 (Pubitemid 29278791)
-
(1999)
Journal of Endocrinology
, vol.161
, Issue.3
, pp. 357-364
-
-
Ilieva, A.1
Yuan, S.2
Wang, R.N.3
Agapitos, D.4
Hill, D.J.5
Rosenberg, L.6
-
9
-
-
0032509446
-
2+ concentration
-
Efanova IB, Zaitsev SV, Zhivotovsky B, Kohler M, Efendic S, Orrenius S, Berggren PO. Glucose and tolbutamide induce apoptosis in pancreatic β-cells: a process dependent on intracellular Ca2+ concentration. J Biol Chem 1998;273:33501-33507 (Pubitemid 129754428)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.50
, pp. 33501-33507
-
-
Efanova, I.B.1
Zaitsev, S.V.2
Zhivotovsky, B.3
Kohler, M.4
Efendic, S.5
Orrenius, S.6
Berggren, P.-O.7
-
10
-
-
0030923812
-
Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells
-
DOI 10.1210/en.138.6.2610
-
Delaney CA, Pavlovic D, Hoorens A, Pipeleers DG, Eizirik DL. Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology 1997;138:2610-2614 (Pubitemid 27215269)
-
(1997)
Endocrinology
, vol.138
, Issue.6
, pp. 2610-2614
-
-
Delaney, C.A.1
Pavlovic, D.2
Hoorens, A.3
Pipeleers, D.G.4
Eizirik, D.L.5
-
11
-
-
0442305381
-
Apoptotic signal transduction pathways in diabetes
-
DOI 10.1016/S0006-2952(03)00494-5, PII S0006295203004945
-
Mandrup-Poulsen T. Apoptotic signal transduction pathways in diabetes. Biochem Pharmacol 2003;66:1433-1440 (Pubitemid 38373330)
-
(2003)
Biochemical Pharmacology
, vol.66
, Issue.8
, pp. 1433-1440
-
-
Mandrup-Poulsen, T.1
-
12
-
-
33645518035
-
Conditional and specific NFκB blockade protects pancreatic β cells from diabetogenic agents
-
Eldor R, Yeffet A Baum K, Doviner V, Amar D, Ben Neriah Y, Christofori G, Peled A, Carel JC, Boitard C, Klein T, Serup P, Eizirik DL, Melloul D. Conditional and specific NFκB blockade protects pancreatic β cells from diabetogenic agents. Proc Natl Acad Sci U S A 2006;103:5072-5077
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5072-5077
-
-
Eldor, R.1
Yeffet, A.2
Baum, K.3
Doviner, V.4
Amar, D.5
Ben Neriah, Y.6
Christofori, G.7
Peled, A.8
Carel, J.C.9
Boitard, C.10
Klein, T.11
Serup, P.12
Eizirik, D.L.13
Melloul, D.14
-
14
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell 2007;129:1261-1274
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
15
-
-
0034781057
-
Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα
-
Tuttle RL, Gill NS, Pugh W, Lee JP, Koeberlein B, Furth EE, Polonsky KS, Naji A, Birnbaum MJ. Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα. Nat Med 2001;7:1133-1137
-
(2001)
Nat Med
, vol.7
, pp. 1133-1137
-
-
Tuttle, R.L.1
Gill, N.S.2
Pugh, W.3
Lee, J.P.4
Koeberlein, B.5
Furth, E.E.6
Polonsky, K.S.7
Naji, A.8
Birnbaum, M.J.9
-
16
-
-
0035210374
-
Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia
-
Bernal-Mizrachi E, Wen W, Stahlhut S, Welling CM, Permutt MA. Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia. J Clin Invest 2001;108:1631-1638
-
(2001)
J Clin Invest
, vol.108
, pp. 1631-1638
-
-
Bernal-Mizrachi, E.1
Wen, W.2
Stahlhut, S.3
Welling, C.M.4
Permutt, M.A.5
-
17
-
-
55849111942
-
Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation
-
Alliouachene S, Tuttle RL, Boumard S, Lapointe T, Berissi S, Germain S, Jaubert F, Tosh D, Birnbaum MJ, Pende M. Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation. J Clin Invest 2008;118:3629-3638
-
(2008)
J Clin Invest
, vol.118
, pp. 3629-3638
-
-
Alliouachene, S.1
Tuttle, R.L.2
Boumard, S.3
Lapointe, T.4
Berissi, S.5
Germain, S.6
Jaubert, F.7
Tosh, D.8
Birnbaum, M.J.9
Pende, M.10
-
18
-
-
0034928845
-
Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP
-
DOI 10.1128/MCB.21.16.5346-5358.2001
-
Yang J-Y, Widmann C. Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP. Mol Cell Biol 2001;21:5346-5358 (Pubitemid 32702440)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.16
, pp. 5346-5358
-
-
Yang, J.-Y.1
Widmann, C.2
-
19
-
-
0037177856
-
The RasGAP N-terminal fragment generated by caspase cleavage protects cells in a Ras/PI3K/Akt-dependent manner that does not rely on NFκB activation
-
DOI 10.1074/jbc.M111540200
-
Yang J-Y, Widmann C. The RasGAP N-terminal fragment generated by caspase cleavage protects cells in a Ras/PI3K/Akt-dependent manner that does not rely on NFκB activation. J Biol Chem 2002;277:14641-14646 (Pubitemid 34952532)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.17
, pp. 14641-14646
-
-
Yang, J.-Y.1
Widmann, C.2
-
20
-
-
23044488799
-
Impaired Akt activity down-modulation, caspase-3 activation, and apoptosis in cells expressing a caspase-resistant mutant of RasGAP at position 157
-
DOI 10.1091/mbc.E05-01-0080
-
Yang J-Y, Walicki J, Michod D, Dubuis G, Widmann C. Impaired Akt activity down-modulation, caspase-3 activation, and apoptosis in cells expressing a caspase-resistant mutant of RasGAP at position 157. Mol Biol Cell 2005;16:3511-3520 (Pubitemid 41077065)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.8
, pp. 3511-3520
-
-
Yang, J.-Y.1
Walicki, J.2
Michod, D.3
Dubuis, G.4
Widmann, C.5
-
21
-
-
25444486206
-
Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion
-
DOI 10.1074/jbc.M504058200
-
Yang J-Y, Walicki J, Abderrahmani A, Cornu M, Waeber G, Thorens B, Widmann C. Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion. J Biol Chem 2005;280:32835-32842 (Pubitemid 41368331)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.38
, pp. 32835-32842
-
-
Yang, J.-Y.1
Walicki, J.2
Abdenrahmani, A.3
Cornu, M.4
Waeber, G.5
Thorens, B.6
Widmann, C.7
-
22
-
-
55949096307
-
Generation of a tightly regulated all-cis beta cell-specific tetracycline-inducible vector
-
Bulat N, Widmann C. Generation of a tightly regulated all-cis beta cell-specific tetracycline-inducible vector. BioTechniques 2008;45:411-420
-
(2008)
BioTechniques
, vol.45
, pp. 411-420
-
-
Bulat, N.1
Widmann, C.2
-
23
-
-
8644273229
-
Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions
-
DOI 10.1128/MCB.24.23.10425-10436.2004
-
Yang J-Y, Michod D, Walicki J, Murphy BM, Kasibhatla S, Martin S, Widmann C. Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions. Mol Cell Biol 2004;24:10425-10436 (Pubitemid 39507879)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.23
, pp. 10425-10436
-
-
Yang, J.-Y.1
Michod, D.2
Walicki, J.3
Murphy, B.M.4
Kasibhatla, S.5
Martin, S.J.6
Widmann, C.7
-
24
-
-
0031667779
-
Apoptosis and the pathogenesis of IDDM: A question of life and death
-
DOI 10.2337/diabetes.47.10.1537
-
Mauricio D, Mandrup-Poulsen T. Apoptosis and the pathogenesis of IDDM: a question of life and death. Diabetes 1998;47:1537-1543 (Pubitemid 28445339)
-
(1998)
Diabetes
, vol.47
, Issue.10
, pp. 1537-1543
-
-
Mauricio, D.1
Mandrup-Poulsen, T.2
-
25
-
-
0028973284
-
Interleukin-1beta-induced nitric oxide synthase expression by rat pancreatic beta-cells: Evidence for the involvement of nuclear factor kappaB in the signaling mechanism
-
DOI 10.1210/en.136.11.4790
-
Kwon G, Corbett JA, Rodi CP, Sullivan P, McDaniel ML. Interleukin-1 beta-induced nitric oxide synthase expression by rat pancreatic beta-cells: evidence for the involvement of nuclear factor kappa B in the signaling mechanism. Endocrinology 1995;136:4790-4795 (Pubitemid 3002171)
-
(1995)
Endocrinology
, vol.136
, Issue.11
, pp. 4790-4795
-
-
Kwon, G.1
Corbett, J.A.2
Rodi, C.P.3
Sullivan, P.4
McDaniel, M.L.5
-
26
-
-
0034101423
-
Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas
-
DOI 10.1002/(SICI)1526-968X(200002)26:2<139::AID-GENE12>3.0.CO;2-7
-
Gannon M, Shiota C, Postic C, Wright CV, Magnuson M. Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas. Genesis 2000;26:139-142 (Pubitemid 30158100)
-
(2000)
Genesis
, vol.26
, Issue.2
, pp. 139-142
-
-
Gannon, M.1
Shiota, C.2
Postic, C.3
Wright, C.V.E.4
Magnuson, M.5
-
27
-
-
2942523253
-
Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice
-
Gorogawa S, Fujitani Y, Kaneto H, Hazama Y, Watada H, Miyamoto Y, Takeda K, Akira S, Magnuson MA, Yamasaki Y, Kajimoto Y, Hori M. Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice. Biochem Biophys Res Commun 2004;319:1159-1170
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 1159-1170
-
-
Gorogawa, S.1
Fujitani, Y.2
Kaneto, H.3
Hazama, Y.4
Watada, H.5
Miyamoto, Y.6
Takeda, K.7
Akira, S.8
Magnuson, M.A.9
Yamasaki, Y.10
Kajimoto, Y.11
Hori, M.12
-
28
-
-
1642586272
-
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
-
DOI 10.1038/nature02369
-
Wendel HG, De Stanchina E, Fridman JS, Malina A, Ray S, Kogan S, Cordon-Cardo C, Pelletier J, Lowe SW. Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature 2004;428:332-337 (Pubitemid 38418805)
-
(2004)
Nature
, vol.428
, Issue.6980
, pp. 332-337
-
-
Wendel, H.-G.1
De Stanchina, E.2
Fridman, J.S.3
Malina, A.4
Ray, S.5
Kogan, S.6
Cordon-Cardo, C.7
Pelletier, J.8
Lowe, S.W.9
-
29
-
-
12144279068
-
Nuclear factor-κB activity in β-cells is required for glucose-stimulated insulin secretion
-
Norlin S, Ahlgren U, Edlund H. Nuclear factor-κB activity in β-cells is required for glucose-stimulated insulin secretion. Diabetes 2005;54:125-132
-
(2005)
Diabetes
, vol.54
, pp. 125-132
-
-
Norlin, S.1
Ahlgren, U.2
Edlund, H.3
-
30
-
-
0031686176
-
Effector mechanisms in low-dose streptozotocin-induced diabetes
-
Lukic ML, Stosic-Grujicic S, Shahin A. Effector mechanisms in low-dose streptozotocin-induced diabetes. Dev Immunol 1998;6:119-128 (Pubitemid 28409872)
-
(1998)
Developmental Immunology
, vol.6
, Issue.1-2
, pp. 119-128
-
-
Lukic, M.L.1
Stosic-Grujicic, S.2
Shahin, A.3
-
31
-
-
17844392396
-
Tumor suppressor p53 inhibits autoimmune inflammation and macrophage function
-
Zheng SJ, Lamhamedi-Cherradi SE, Wang P, Xu L, Chen YH. Tumor suppressor p53 inhibits autoimmune inflammation and macrophage function. Diabetes 2005;54:1423-1428
-
(2005)
Diabetes
, vol.54
, pp. 1423-1428
-
-
Zheng, S.J.1
Lamhamedi-Cherradi, S.E.2
Wang, P.3
Xu, L.4
Chen, Y.H.5
-
32
-
-
37549029242
-
The mechanisms of alloxan- and streptozotocin-induced diabetes
-
Lenzen S. The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia 2008;51:216-226
-
(2008)
Diabetologia
, vol.51
, pp. 216-226
-
-
Lenzen, S.1
-
33
-
-
0035856952
-
β-Cell death during progression to diabetes
-
Mathis D, Vence L, Benoist C. β-Cell death during progression to diabetes. Nature 2001;414:792-798
-
(2001)
Nature
, vol.414
, pp. 792-798
-
-
Mathis, D.1
Vence, L.2
Benoist, C.3
-
34
-
-
12344323484
-
Type 2 diabetes: A matter of beta-cell life and death?
-
Rhodes CJ. Type 2 diabetes: a matter of beta-cell life and death? Science 2005;307:380-384
-
(2005)
Science
, vol.307
, pp. 380-384
-
-
Rhodes, C.J.1
-
35
-
-
0034932098
-
The accelerator hypothesis: Weight gain as the missing link between type I and type II diabetes
-
Wilkin TJ. The accelerator hypothesis: weight gain as the missing link between type I and type II diabetes. Diabetologia 2001;44:914-922
-
(2001)
Diabetologia
, vol.44
, pp. 914-922
-
-
Wilkin, T.J.1
-
36
-
-
0036738398
-
Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets
-
DOI 10.1172/JCI200215318
-
Maedler K, Sergeev P, Ris F, Oberholzer J, Joller-Jemelka HI, Spinas GA, Kaiser N, Halban PA, Donath MY. Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets. J Clin Invest 2002;110:851-860 (Pubitemid 35050963)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.6
, pp. 851-860
-
-
Maedler, K.1
Sergeev, P.2
Ris, F.3
Oberholzer, J.4
Joller-Jemelka, H.I.5
Spinas, G.A.6
Kaiser, N.7
Halban, P.A.8
Donath, M.Y.9
-
37
-
-
0035432491
-
Glucose Induces β-Cell Apoptosis Via Upregulation of the Fas Receptor in Human Islets
-
Maedler K, Spinas GA, Lehmann R, Sergeev P, Weber M, Fontana A, Kaiser N, Donath MY. Glucose induces β-cell apoptosis via upregulation of the Fas receptor in human islets. Diabetes 2001;50:1683-1690 (Pubitemid 33641583)
-
(2001)
Diabetes
, vol.50
, Issue.8
, pp. 1683-1690
-
-
Maedler, K.1
Spinas, G.A.2
Lehmann, R.3
Sergeev, P.4
Weber, M.5
Fontana, A.6
Kaiser, N.7
Donath, M.Y.8
-
38
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
DOI 10.2337/diabetes.52.1.102
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. β-Cell deficit and increased β-cell apoptosis in humans with type 2 diabetes. Diabetes 2003;52:102-110 (Pubitemid 36042113)
-
(2003)
Diabetes
, vol.52
, Issue.1
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
39
-
-
2942683422
-
Abdominal obesity and dyslipidemia in the metabolic syndrome: Importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk
-
Carr MC, Brunzell JD. Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk. J Clin Endocrinol Metab 2004;89:2601-2607
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2601-2607
-
-
Carr, M.C.1
Brunzell, J.D.2
-
40
-
-
32544435755
-
New insights into fatty acid modulation of pancreatic β-cell function
-
DOI 10.1016/S0074-7696(06)48001-3, PII S0074769606480013, A Survey of Cell Biology
-
Haber EP, Procopio J, Carvalho CR, Carpinelli AR, Newsholme P, Curi R. New insights into fatty acid modulation of pancreatic β-cell function. Int Rev Cytol 2006;248:1-41 (Pubitemid 43238169)
-
(2006)
International Review of Cytology
, vol.248
, pp. 1-41
-
-
Haber, E.P.1
Procopio, J.2
Carvalho, C.R.O.3
Carpinelli, A.R.4
Newsholme, P.5
Curi, R.6
-
41
-
-
0036097472
-
β-Cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia
-
Biarnes M, Montolio M, Nacher V, Raurell M, Soler J, Montanya E. β-Cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia. Diabetes 2002;51:66-72
-
(2002)
Diabetes
, vol.51
, pp. 66-72
-
-
Biarnes, M.1
Montolio, M.2
Nacher, V.3
Raurell, M.4
Soler, J.5
Montanya, E.6
-
42
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance
-
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest 1995;95:2409-2415
-
(1995)
J Clin Invest
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
43
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87-91 (Pubitemid 23036092)
-
(1993)
Science
, vol.259
, Issue.5091
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
44
-
-
0033517189
-
NF-κB activation by tumour necrosis factor requires tie Akt serine- Threonine kinase
-
DOI 10.1038/43466
-
Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NFκB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 1999;401:82-85 (Pubitemid 29418447)
-
(1999)
Nature
, vol.401
, Issue.6748
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
45
-
-
33846928411
-
NFκB prevents β cell death and autoimmune diabetes in NOD mice
-
Kim S, Millet I, Kim HS, Kim JY, Han MS, Lee MK, Kim KW, Sherwin RS, Karin M, Lee MS. NFκB prevents β cell death and autoimmune diabetes in NOD mice. Proc Natl Acad Sci U S A 2007;104:1913-1918
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 1913-1918
-
-
Kim, S.1
Millet, I.2
Kim, H.S.3
Kim, J.Y.4
Han, M.S.5
Lee, M.K.6
Kim, K.W.7
Sherwin, R.S.8
Karin, M.9
Lee, M.S.10
-
46
-
-
33645519850
-
Inhibition of apoptosis by survivin improves transplantation of pancreatic islets for treatment of diabetes in mice
-
Dohi T, Salz W, Costa M, Ariyan C, Basadonna GP, Altieri DC. Inhibition of apoptosis by survivin improves transplantation of pancreatic islets for treatment of diabetes in mice. EMBO Rep 2006;7:438-443
-
(2006)
EMBO Rep
, vol.7
, pp. 438-443
-
-
Dohi, T.1
Salz, W.2
Costa, M.3
Ariyan, C.4
Basadonna, G.P.5
Altieri, D.C.6
-
47
-
-
0242584873
-
+/- mice
-
+/- mice. J Clin Invest 2003;111:1147-1160
-
(2003)
J Clin Invest
, vol.111
, pp. 1147-1160
-
-
Johnson, J.D.1
Ahmed, N.T.2
Luciani, D.S.3
Han, Z.4
Tran, H.5
Fujita, J.6
Misler, S.7
Edlund, H.8
Polonsky, K.S.9
-
48
-
-
2042419553
-
The NOD mouse: A model for insulidependent diabetes mellitis
-
Coligan JE, Bierer BE, Margulies DH, Shevach EM, Strober W, Eds. John Wiley & Sons
-
Leiter EH. The NOD mouse: a model for insulidependent diabetes mellitis. In Current Protocols in Immunology. Coligan JE, Bierer BE, Margulies DH, Shevach EM, Strober W, Eds. John Wiley & Sons, 1997, p. 15.9.1-15.9.23
-
(1997)
Current Protocols in Immunology
-
-
Leiter, E.H.1
|