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Volumn 47, Issue 1, 2009, Pages 8-11

The role of the activating receptor NKG2D in autoimmunity

Author keywords

Autoreactivity; Celiac disease; Crohn's disease; Danger signals; Lupus; Multiple sclerosis; Rheumatoid arthritis; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; IMMUNOMODULATING AGENT; NATURAL KILLER CELL RECEPTOR NKG2D; NATURAL KILLER CELL RECEPTOR NKG2D ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

EID: 70350400641     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.02.023     Document Type: Review
Times cited : (49)

References (50)
  • 3
    • 0037123607 scopus 로고    scopus 로고
    • Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors
    • Arase H., Mocarski E.S., Campbell A.E., Hill A.B., and Lanier L.L. Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors. Science 296 (2002) 1323-1326
    • (2002) Science , vol.296 , pp. 1323-1326
    • Arase, H.1    Mocarski, E.S.2    Campbell, A.E.3    Hill, A.B.4    Lanier, L.L.5
  • 4
    • 0035928391 scopus 로고    scopus 로고
    • Type 1 diabetes: new perspectives on disease pathogenesis and treatment
    • Atkinson M.A., and Eisenbarth G.S. Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet 358 (2001) 221-229
    • (2001) Lancet , vol.358 , pp. 221-229
    • Atkinson, M.A.1    Eisenbarth, G.S.2
  • 5
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • Bauer S., Groh V., Wu J., Steinle A., Phillips J.H., Lanier L.L., and Spies T. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285 (1999) 727-729
    • (1999) Science , vol.285 , pp. 727-729
    • Bauer, S.1    Groh, V.2    Wu, J.3    Steinle, A.4    Phillips, J.H.5    Lanier, L.L.6    Spies, T.7
  • 6
    • 38149047616 scopus 로고    scopus 로고
    • Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease
    • Bhagat G., Naiyer A.J., Shah J.G., Harper J., Jabri B., Wang T.C., Green P.H., and Manavalan J.S. Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease. J. Clin. Invest. 118 (2008) 281-293
    • (2008) J. Clin. Invest. , vol.118 , pp. 281-293
    • Bhagat, G.1    Naiyer, A.J.2    Shah, J.G.3    Harper, J.4    Jabri, B.5    Wang, T.C.6    Green, P.H.7    Manavalan, J.S.8
  • 8
    • 0037515740 scopus 로고    scopus 로고
    • NKG2D ligands: unconventional MHC Class I-like molecules exploited by viruses and cancer
    • Cerwenka A., and Lanier L.L. NKG2D ligands: unconventional MHC Class I-like molecules exploited by viruses and cancer. Tissue Antigens 61 (2003) 335-343
    • (2003) Tissue Antigens , vol.61 , pp. 335-343
    • Cerwenka, A.1    Lanier, L.L.2
  • 10
    • 0036915968 scopus 로고    scopus 로고
    • Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D
    • Diefenbach A., Tomasello E., Lucas M., Jamieson A.M., Hsia J.K., Vivier E., and Raulet D.H. Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D. Nat. Immunol. 3 (2002) 1142-1149
    • (2002) Nat. Immunol. , vol.3 , pp. 1142-1149
    • Diefenbach, A.1    Tomasello, E.2    Lucas, M.3    Jamieson, A.M.4    Hsia, J.K.5    Vivier, E.6    Raulet, D.H.7
  • 11
    • 34548247599 scopus 로고    scopus 로고
    • Promiscuity and the single receptor: NKG2D
    • Eagle R.A., and Trowsdale J. Promiscuity and the single receptor: NKG2D. Nat. Rev. Immunol. 7 (2007) 737-744
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 737-744
    • Eagle, R.A.1    Trowsdale, J.2
  • 14
    • 18844365992 scopus 로고    scopus 로고
    • A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules
    • Fernandez N.C., Treiner E., Vance R.E., Jamieson A.M., Lemieux S., and Raulet D.H. A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood 105 (2005) 4416-4423
    • (2005) Blood , vol.105 , pp. 4416-4423
    • Fernandez, N.C.1    Treiner, E.2    Vance, R.E.3    Jamieson, A.M.4    Lemieux, S.5    Raulet, D.H.6
  • 16
    • 31144455653 scopus 로고    scopus 로고
    • Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis
    • Galazka G., Stasiolek M., Walczak A., Jurewicz A., Zylicz A., Brosnan C.F., Raine C.S., and Selmaj K.W. Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis. J. Immunol. 176 (2006) 1588-1599
    • (2006) J. Immunol. , vol.176 , pp. 1588-1599
    • Galazka, G.1    Stasiolek, M.2    Walczak, A.3    Jurewicz, A.4    Zylicz, A.5    Brosnan, C.F.6    Raine, C.S.7    Selmaj, K.W.8
  • 17
    • 0035139983 scopus 로고    scopus 로고
    • Danger signals: SOS to the immune system
    • Gallucci S., and Matzinger P. Danger signals: SOS to the immune system. Curr. Opin. Immunol. 13 (2001) 114-119
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 114-119
    • Gallucci, S.1    Matzinger, P.2
  • 18
    • 0036910991 scopus 로고    scopus 로고
    • NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation
    • Gilfillan S., Ho E.L., Cella M., Yokoyama W.M., and Colonna M. NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. Nat. Immunol. 3 (2002) 1150-1155
    • (2002) Nat. Immunol. , vol.3 , pp. 1150-1155
    • Gilfillan, S.1    Ho, E.L.2    Cella, M.3    Yokoyama, W.M.4    Colonna, M.5
  • 19
    • 0041422233 scopus 로고    scopus 로고
    • Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis
    • Groh V., Bruhl A., El-Gabalawy H., Nelson J.L., and Spies T. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 100 (2003) 9452-9457
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9452-9457
    • Groh, V.1    Bruhl, A.2    El-Gabalawy, H.3    Nelson, J.L.4    Spies, T.5
  • 20
    • 33745183385 scopus 로고    scopus 로고
    • Fas-ligand-mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity
    • Groh V., Smythe K., Dai Z., and Spies T. Fas-ligand-mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity. Nat. Immunol. 7 (2006) 755-762
    • (2006) Nat. Immunol. , vol.7 , pp. 755-762
    • Groh, V.1    Smythe, K.2    Dai, Z.3    Spies, T.4
  • 21
    • 0037126310 scopus 로고    scopus 로고
    • Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
    • Groh V., Wu J., Yee C., and Spies T. Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 419 (2002) 734-738
    • (2002) Nature , vol.419 , pp. 734-738
    • Groh, V.1    Wu, J.2    Yee, C.3    Spies, T.4
  • 22
    • 36248957695 scopus 로고    scopus 로고
    • NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway
    • Horng T., Bezbradica J.S., and Medzhitov R. NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway. Nat. Immunol. 8 (2007) 1345-1352
    • (2007) Nat. Immunol. , vol.8 , pp. 1345-1352
    • Horng, T.1    Bezbradica, J.S.2    Medzhitov, R.3
  • 24
    • 0035801332 scopus 로고    scopus 로고
    • A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis
    • Huseby E.S., Liggitt D., Brabb T., Schnabel B., Ohlen C., and Goverman J. A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis. J. Exp. Med. 194 (2001) 669-676
    • (2001) J. Exp. Med. , vol.194 , pp. 669-676
    • Huseby, E.S.1    Liggitt, D.2    Brabb, T.3    Schnabel, B.4    Ohlen, C.5    Goverman, J.6
  • 26
    • 34250367967 scopus 로고    scopus 로고
    • Inhibition of NKG2D receptor function by antibody therapy attenuates transfer-induced colitis in SCID mice
    • Kjellev S., Haase C., Lundsgaard D., Urso B., Tornehave D., and Markholst H. Inhibition of NKG2D receptor function by antibody therapy attenuates transfer-induced colitis in SCID mice. Eur. J. Immunol. 37 (2007) 1397-1406
    • (2007) Eur. J. Immunol. , vol.37 , pp. 1397-1406
    • Kjellev, S.1    Haase, C.2    Lundsgaard, D.3    Urso, B.4    Tornehave, D.5    Markholst, H.6
  • 28
    • 11144299492 scopus 로고    scopus 로고
    • NK cell recognition
    • Lanier L.L. NK cell recognition. Annu. Rev. Immunol. 23 (2005) 225-274
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 225-274
    • Lanier, L.L.1
  • 29
    • 33748500822 scopus 로고    scopus 로고
    • Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells
    • Ly D., Mi Q.S., Hussain S., and Delovitch T.L. Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells. J. Immunol. 177 (2006) 3695-3704
    • (2006) J. Immunol. , vol.177 , pp. 3695-3704
    • Ly, D.1    Mi, Q.S.2    Hussain, S.3    Delovitch, T.L.4
  • 32
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12 (1994) 991-1045
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 33
    • 0032191916 scopus 로고    scopus 로고
    • An innate sense of danger
    • Matzinger P. An innate sense of danger. Semin. Immunol. 10 (1998) 399-415
    • (1998) Semin. Immunol. , vol.10 , pp. 399-415
    • Matzinger, P.1
  • 36
    • 14544283396 scopus 로고    scopus 로고
    • Killer cell immunoglobulin-like receptor genes in Latvian patients with type 1 diabetes mellitus and healthy controls
    • Nikitina-Zake L., Rajalingham R., Rumba I., and Sanjeevi C.B. Killer cell immunoglobulin-like receptor genes in Latvian patients with type 1 diabetes mellitus and healthy controls. Ann. N Y Acad. Sci. 1037 (2004) 161-169
    • (2004) Ann. N Y Acad. Sci. , vol.1037 , pp. 161-169
    • Nikitina-Zake, L.1    Rajalingham, R.2    Rumba, I.3    Sanjeevi, C.B.4
  • 39
    • 29444455376 scopus 로고    scopus 로고
    • NKG2D in NK and T cell-mediated immunity
    • Ogasawara K., and Lanier L.L. NKG2D in NK and T cell-mediated immunity. J. Clin. Immunol. 25 (2005) 534-540
    • (2005) J. Clin. Immunol. , vol.25 , pp. 534-540
    • Ogasawara, K.1    Lanier, L.L.2
  • 41
    • 57449089601 scopus 로고    scopus 로고
    • Increased proportion of CD56bright natural killer cells in active and inactive systemic lupus erythematosus
    • Schepis D., Gunnarsson I., Eloranta M.L., Lampa J., Jacobson S.H., Karre K., and Berg L. Increased proportion of CD56bright natural killer cells in active and inactive systemic lupus erythematosus. Immunology 126 (2009) 140-146
    • (2009) Immunology , vol.126 , pp. 140-146
    • Schepis, D.1    Gunnarsson, I.2    Eloranta, M.L.3    Lampa, J.4    Jacobson, S.H.5    Karre, K.6    Berg, L.7
  • 42
    • 36249023845 scopus 로고    scopus 로고
    • In vivo expression pattern of MICA and MICB and its relevance to auto-immunity and cancer
    • Schrambach S., Ardizzone M., Leymarie V., Sibilia J., and Bahram S. In vivo expression pattern of MICA and MICB and its relevance to auto-immunity and cancer. PLoS ONE 2 (2007) e518
    • (2007) PLoS ONE , vol.2
    • Schrambach, S.1    Ardizzone, M.2    Leymarie, V.3    Sibilia, J.4    Bahram, S.5
  • 43
    • 27144461731 scopus 로고    scopus 로고
    • Is celiac disease an autoimmune disorder?
    • Sollid L.M., and Jabri B. Is celiac disease an autoimmune disorder?. Curr. Opin. Immunol. 17 (2005) 595-600
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 595-600
    • Sollid, L.M.1    Jabri, B.2
  • 44
    • 33646798786 scopus 로고    scopus 로고
    • Celiac disease-sandwiched between innate and adaptive immunity
    • Stepniak D., and Koning F. Celiac disease-sandwiched between innate and adaptive immunity. Hum. Immunol. 67 (2006) 460-468
    • (2006) Hum. Immunol. , vol.67 , pp. 460-468
    • Stepniak, D.1    Koning, F.2
  • 47
    • 33644972706 scopus 로고    scopus 로고
    • How do natural killer cells find self to achieve tolerance?
    • Yokoyama W.M., and Kim S. How do natural killer cells find self to achieve tolerance?. Immunity 24 (2006) 249-257
    • (2006) Immunity , vol.24 , pp. 249-257
    • Yokoyama, W.M.1    Kim, S.2
  • 48
    • 0021966856 scopus 로고
    • T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination
    • Zamvil S., Nelson P., Trotter J., Mitchell D., Knobler R., Fritz R., and Steinman L. T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination. Nature 317 (1985) 355-358
    • (1985) Nature , vol.317 , pp. 355-358
    • Zamvil, S.1    Nelson, P.2    Trotter, J.3    Mitchell, D.4    Knobler, R.5    Fritz, R.6    Steinman, L.7
  • 49
    • 0030712367 scopus 로고    scopus 로고
    • Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells
    • Zhang B., Yamamura T., Kondo T., Fujiwara M., and Tabira T. Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells. J. Exp. Med. 186 (1997) 1677-1687
    • (1997) J. Exp. Med. , vol.186 , pp. 1677-1687
    • Zhang, B.1    Yamamura, T.2    Kondo, T.3    Fujiwara, M.4    Tabira, T.5
  • 50
    • 41149176392 scopus 로고    scopus 로고
    • Interleukin-15 improves cytotoxicity of natural killer cells via up-regulating NKG2D and cytotoxic effector molecule expression as well as STAT1 and ERK1/2 phosphorylation
    • Zhang C., Zhang J., Niu J., and Tian Z. Interleukin-15 improves cytotoxicity of natural killer cells via up-regulating NKG2D and cytotoxic effector molecule expression as well as STAT1 and ERK1/2 phosphorylation. Cytokine 42 (2008) 128-136
    • (2008) Cytokine , vol.42 , pp. 128-136
    • Zhang, C.1    Zhang, J.2    Niu, J.3    Tian, Z.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.