Inhibition of NKG2D receptor function by antibody therapy attenuates transfer-induced colitis in SCID mice

European Journal of Immunology

Volumn 37, Issue 5, 2007, Pages 1397-1406

  Kjellev, Stine ^a   Haase, Claus ^a,b   Lundsgaard, Dorthe ^a,b   Ursø, Birgitte ^a   Tornehave, Ditte ^a   Markholst, Helle ^a,b  

^a NOVO NORDISK A S   (Denmark)

^b HAGEDORN RESEARCH INSTITUTE   (Denmark)

Author keywords

Adoptive transfer model; Colitis; Inflammatory bowel disease; NKG2D

Indexed keywords

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CX5; NATURAL KILLER CELL RECEPTOR NKG2D; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CD4+ CD25+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; COLITIS; COLON; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; EARLY INTERVENTION; FEMALE; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; RECEPTOR BLOCKING; SCID MOUSE; SPLEEN; STRAIN DIFFERENCE;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES, MONOCLONAL; CD4-POSITIVE T-LYMPHOCYTES; COLITIS; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; KILLER CELLS, NATURAL; MICE; MICE, SCID; RECEPTORS, IMMUNOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTE SUBSETS;

EID: 34250367967     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200636473     Document Type: Article

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