Spinal antinociception evoked by the triterpene 3β, 6β, 16β-trihydroxylup-20(29)-ene in mice: Evidence for the involvement of the glutamatergic system via NMDA and metabotropic glutamate receptors

European Journal of Pharmacology

Volumn 623, Issue 1-3, 2009, Pages 30-36

  Longhi Balbinot, Daniela Tagliari ^a   Pietrovski, Evelise Fernandes ^b   Gadotti, Vinicius Maria ^a   Martins, Daniel Fernandes ^a   Facundo, Valdir Alves ^c   Santos, Adair Roberto Soares ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^c UNIVERSIDADE FEDERAL DE RONDÔNIA   (Brazil)

Author keywords

Antinociception; Ionotropic glutamate receptor; Metabotropic glutamate receptor; Triterpene

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 3BETA,6BETA,16BETA TRIHYDROXYLUP 20(29)ENE; 4 CARBOXY 2 METHYLPHENYLGLYCINE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; DIZOCILPINE; DIZOCILPINE MALEATE; GLUTAMIC ACID; KAINIC ACID; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TRITERPENE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; LEG PAIN; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; GLUTAMIC ACID; INJECTIONS, SPINAL; MICE; MOTOR ACTIVITY; NEUROTRANSMITTER AGENTS; NOCICEPTORS; PAIN MEASUREMENT; RECEPTORS, GLUTAMATE; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD; TRITERPENES;

EID: 70350323705     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.09.004     Document Type: Article

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