Glutamate receptors and nociception: Implications for the drug treatment of pain

CNS Drugs

Volumn 15, Issue 1, 2001, Pages 29-58

  Fundytus, Marian E ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; DECAHYDRO 6 [2 (1H TETRAZOL 5 YL)ETHYL] 3 ISOQUINOLINECARBOXYLIC ACID; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; IONOTROPIC RECEPTOR; KAINIC ACID; KAINIC ACID RECEPTOR ANTAGONIST; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OPIATE; OPIATE RECEPTOR;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; DRUG EFFECT; DRUG EFFICACY; DRUG RECEPTOR BINDING; HUMAN; NEUROTRANSMITTER RELEASE; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; REVIEW; SIDE EFFECT;

EID: 0035152963     PISSN: 11727047     EISSN: None     Source Type: Journal    
DOI: 10.2165/00023210-200115010-00004     Document Type: Review

References (5)

1. Nakanishi S. Molecular diversity of glutamate receptors and implications for brain function. Science 1992; 258: 597-603
2. MacDermott AB, Mayer ML, Westbrook GL, et al. NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones. Nature 1986; 321: 519-22
3. Mayer ML, MacDermott AB, Westbrook GL, et al. Agonist- and voltage-gated calcium entry in cultured mouse spinal cord neurons under voltage clamp measured using Arsenazo III. J Neurosci 1987; 7: 3230-44
4. Nowak L, Bregstovski P, Ascher P, et al. Magnesium gates glutamate-activated channels in mouse central neurones. Nature 1984; 307: 462-5
5. 2+ of NMDA responses in spinal cord neurones. Nature 1984; 309: 261-3