메뉴 건너뛰기




Volumn 20, Issue 19, 2009, Pages 4183-4193

Udu deficiency activates DNA damage checkpoint

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 2; MINICHROMOSOME MAINTENANCE PROTEIN 3; MINICHROMOSOME MAINTENANCE PROTEIN 4; MUTANT PROTEIN; PROTEIN P53; PROTEIN UDU; UNCLASSIFIED DRUG;

EID: 70350231531     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E09-02-0109     Document Type: Article
Times cited : (14)

References (69)
  • 1
    • 85047671736 scopus 로고    scopus 로고
    • The SANT domain: A putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB
    • Aasland, R., Stewart, A. F., and Gibson, T. (1996). The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. Trends Biochem. Sci. 21, 87-88.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 87-88
    • Aasland, R.1    Stewart, A.F.2    Gibson, T.3
  • 2
    • 0037829284 scopus 로고    scopus 로고
    • Checkpoint signaling: Epigenetic events sound the DNA strand-breaks alarm to the ATM protein kinase
    • Abraham, R. T. (2003). Checkpoint signaling: epigenetic events sound the DNA strand-breaks alarm to the ATM protein kinase. Bioessays 25, 627-630.
    • (2003) Bioessays , vol.25 , pp. 627-630
    • Abraham, R.T.1
  • 3
    • 0842324624 scopus 로고    scopus 로고
    • MCM proteins: DNA damage, mutagenesis and repair
    • Bailis, J. M., and Forsburg, S. L. (2004). MCM proteins: DNA damage, mutagenesis and repair. Curr. Opin. Genet. Dev. 14, 17-21.
    • (2004) Curr. Opin. Genet. Dev. , vol.14 , pp. 17-21
    • Bailis, J.M.1    Forsburg, S.L.2
  • 4
    • 0035997368 scopus 로고    scopus 로고
    • DNA replication in eukaryotic cells
    • Bell, S. P., and Dutta, A. (2002). DNA replication in eukaryotic cells. Annu. Rev. Biochem. 71, 333-374.
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 333-374
    • Bell, S.P.1    Dutta, A.2
  • 5
    • 0034282102 scopus 로고    scopus 로고
    • An intact HDM2 RING-finger domain is required for nuclear exclusion of p53
    • Boyd, S. D., Tsai, K. Y., and Jacks, T. (2000). An intact HDM2 RING-finger domain is required for nuclear exclusion of p53. Nat. Cell Biol. 2, 563-568.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 563-568
    • Boyd, S.D.1    Tsai, K.Y.2    Jacks, T.3
  • 6
    • 0036809731 scopus 로고    scopus 로고
    • Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes
    • DOI 10.1016/S1097-2765(02)00634-2
    • Boyer, L. A., Langer, M. R., Crowley, K. A., Tan, S., Denu, J. M., and Peterson, C. L. (2002). Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes. Mol. Cell 10, 935-942. (Pubitemid 35335647)
    • (2002) Molecular Cell , vol.10 , Issue.4 , pp. 935-942
    • Boyer, L.A.1    Langer, M.R.2    Crowley, K.A.3    Tan, S.4    Denu, J.M.5    Peterson, C.L.6
  • 7
  • 9
    • 0033598754 scopus 로고    scopus 로고
    • Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
    • Chehab, N. H., Malikzay, A., Stavridi, E. S., and Halazonetis, T. D. (1999). Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage. Proc. Natl. Acad. Sci. USA 96, 13777-13782.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 13777-13782
    • Chehab, N.H.1    Malikzay, A.2    Stavridi, E.S.3    Halazonetis, T.D.4
  • 10
    • 3042798440 scopus 로고    scopus 로고
    • Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases
    • Cortez, D., Glick, G., and Elledge, S. J. (2004). Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases. Proc. Natl. Acad. Sci. USA 101, 10078-10083.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 10078-10083
    • Cortez, D.1    Glick, G.2    Elledge, S.J.3
  • 11
    • 55449091773 scopus 로고    scopus 로고
    • Mutation of the zebrafish nucleoporin elys sensitizes tissue progenitors to replication stress
    • Davuluri, G., Gong, W., Yusuff, S., Lorent, K., Muthumani, M., Dolan, A. C., and Pack, M. (2008). Mutation of the zebrafish nucleoporin elys sensitizes tissue progenitors to replication stress. PLoS Genet. 4, e1000240.
    • (2008) PLoS Genet. , vol.4
    • Davuluri, G.1    Gong, W.2    Yusuff, S.3    Lorent, K.4    Muthumani, M.5    Dolan, A.C.6    Pack, M.7
  • 12
    • 0037815412 scopus 로고    scopus 로고
    • Mcm7, a subunit of the presumptive MCM helicase, modulates its own expression in conjunction with Mcm1
    • Fitch, M. J., Donato, J. J., and Tye, B. K. (2003). Mcm7, a subunit of the presumptive MCM helicase, modulates its own expression in conjunction with Mcm1. J. Biol. Chem. 278, 25408-25416.
    • (2003) J. Biol. Chem. , vol.278 , pp. 25408-25416
    • Fitch, M.J.1    Donato, J.J.2    Tye, B.K.3
  • 13
    • 0027078830 scopus 로고
    • Genotoxic-stress-response genes and growth-arrest genes. gadd, MyD, and other genes induced by treatments eliciting growth arrest
    • Fornace, A. J., Jr., Jackman, J., Hollander, M. C., Hoffman-Liebermann, B., and Liebermann, D. A. (1992). Genotoxic-stress-response genes and growth-arrest genes. gadd, MyD, and other genes induced by treatments eliciting growth arrest. Ann. N.Y. Acad. Sci. 663, 139-153.
    • (1992) Ann. N.Y. Acad. Sci. , vol.663 , pp. 139-153
    • Fornace Jr., A.J.1    Jackman, J.2    Hollander, M.C.3    Hoffman-Liebermann, B.4    Liebermann, D.A.5
  • 14
    • 1542405310 scopus 로고    scopus 로고
    • Eukaryotic MCM proteins: Beyond replication initiation
    • Forsburg, S. L. (2004). Eukaryotic MCM proteins: beyond replication initiation. Microbiol. Mol. Biol. Rev. 68, 109-131.
    • (2004) Microbiol. Mol. Biol. Rev. , vol.68 , pp. 109-131
    • Forsburg, S.L.1
  • 15
    • 0025906795 scopus 로고
    • Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts
    • Fox, M. H., Arndt-Jovin, D. J., Jovin, T. M., Baumann, P. H., and Robert-Nicoud, M. (1991). Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts. J. Cell Sci. 99, 247-253.
    • (1991) J. Cell Sci. , vol.99 , pp. 247-253
    • Fox, M.H.1    Arndt-Jovin, D.J.2    Jovin, T.M.3    Baumann, P.H.4    Robert-Nicoud, M.5
  • 16
    • 0034672045 scopus 로고    scopus 로고
    • Gon-4, a cell lineage regulator required for gonadogenesis in Caenorhabditis elegans
    • Friedman, L., Santa Anna-Arriola, S., Hodgkin, J., and Kimble, J. (2000). gon-4, a cell lineage regulator required for gonadogenesis in Caenorhabditis elegans. Dev. Biol. 228, 350-362.
    • (2000) Dev. Biol. , vol.228 , pp. 350-362
    • Friedman, L.1    Santa Anna-Arriola, S.2    Hodgkin, J.3    Kimble, J.4
  • 17
    • 0030889245 scopus 로고    scopus 로고
    • In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP
    • Fujita, M., Kiyono, T., Hayashi, Y., and Ishibashi, M. (1997). In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP. J. Biol. Chem. 272, 10928-10935.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10928-10935
    • Fujita, M.1    Kiyono, T.2    Hayashi, Y.3    Ishibashi, M.4
  • 18
    • 27844470581 scopus 로고    scopus 로고
    • Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks
    • Garinis, G. A., et al. (2005). Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks. EMBO J. 24, 3952-3962.
    • (2005) EMBO J. , vol.24 , pp. 3952-3962
    • Garinis, G.A.1
  • 19
    • 0034282220 scopus 로고    scopus 로고
    • The MDM2 RING-finger domain is required to promote p53 nuclear export
    • Geyer, R. K., Yu, Z. K., and Maki, C. G. (2000). The MDM2 RING-finger domain is required to promote p53 nuclear export. Nat. Cell Biol. 2, 569-573.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 569-573
    • Geyer, R.K.1    Yu, Z.K.2    Maki, C.G.3
  • 21
    • 33847083565 scopus 로고    scopus 로고
    • P53 modulation of the DNA damage response
    • Helton, E. S., and Chen, X. (2007). p53 modulation of the DNA damage response. J. Cell. Biochem. 100, 883-896.
    • (2007) J. Cell. Biochem. , vol.100 , pp. 883-896
    • Helton, E.S.1    Chen, X.2
  • 22
    • 9744271049 scopus 로고    scopus 로고
    • Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
    • DOI 10.1158/0008-5472.CAN-04-2727
    • Hickson, I., Zhao, Y., Richardson, C. J., Green, S. J., Martin, N. M., Orr, A. I., Reaper, P. M., Jackson, S. P., Curtin, N. J., and Smith, G. C. (2004). Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res. 64, 9152-9159. (Pubitemid 39665530)
    • (2004) Cancer Research , vol.64 , Issue.24 , pp. 9152-9159
    • Hickson, I.1    Zhao, Y.2    Richardson, C.J.3    Green, S.J.4    Martin, N.M.B.5    Orr, A.I.6    Reaper, P.M.7    Jackson, S.P.8    Curtin, N.J.9    Smith, G.C.M.10
  • 23
    • 0043092109 scopus 로고    scopus 로고
    • Identification of MCM4 as a target of the DNA replication block checkpoint system
    • Ishimi, Y., Komamura-Kohno, Y., Kwon, H. J., Yamada, K., and Nakanishi, M. (2003). Identification of MCM4 as a target of the DNA replication block checkpoint system. J. Biol. Chem. 278, 24644-24650.
    • (2003) J. Biol. Chem. , vol.278 , pp. 24644-24650
    • Ishimi, Y.1    Komamura-Kohno, Y.2    Kwon, H.J.3    Yamada, K.4    Nakanishi, M.5
  • 24
    • 0034753408 scopus 로고    scopus 로고
    • Contribution of base lesions to radiation-induced clustered DNA damage: Implication for models of radiation response
    • Jenner, T. J., Fulford, J., and O'Neill, P. (2001). Contribution of base lesions to radiation-induced clustered DNA damage: implication for models of radiation response. Radiat. Res. 156, 590-593.
    • (2001) Radiat. Res. , vol.156 , pp. 590-593
    • Jenner, T.J.1    Fulford, J.2    O'Neill, P.3
  • 25
    • 0034707072 scopus 로고    scopus 로고
    • Notch signalling and the synchronization of the somite segmentation clock
    • Jiang, Y.-J., Aerne, B. L., Smithers, L., Haddon, C., Ish-Horowicz, D., and Lewis, J. (2000). Notch signalling and the synchronization of the somite segmentation clock. Nature 408, 475-479.
    • (2000) Nature , vol.408 , pp. 475-479
    • Jiang, Y.-J.1    Aerne, B.L.2    Smithers, L.3    Haddon, C.4    Ish-Horowicz, D.5    Lewis, J.6
  • 26
    • 0032537449 scopus 로고    scopus 로고
    • MCM proteins: Evolution, properties, and role in DNA replication
    • Kearsey, S. E., and Labib, K. (1998). MCM proteins: evolution, properties, and role in DNA replication. Biochim. Biophys. Acta 1398, 113-136.
    • (1998) Biochim. Biophys. Acta , vol.1398 , pp. 113-136
    • Kearsey, S.E.1    Labib, K.2
  • 27
    • 0033592868 scopus 로고    scopus 로고
    • Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
    • Khosravi, R., Maya, R., Gottlieb, T., Oren, M., Shiloh, Y., and Shkedy, D. (1999). Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage. Proc. Natl. Acad. Sci. USA 96, 14973-14977.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14973-14977
    • Khosravi, R.1    Maya, R.2    Gottlieb, T.3    Oren, M.4    Shiloh, Y.5    Shkedy, D.6
  • 29
    • 0031007453 scopus 로고    scopus 로고
    • Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs
    • DOI 10.1093/emboj/16.11.3320
    • Kubota, Y., Mimura, S., Nishimoto, S., Masuda, T., Nojima, H., and Takisawa, H. (1997). Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs. EMBO J. 16, 3320-3331. (Pubitemid 27234969)
    • (1997) EMBO Journal , vol.16 , Issue.11 , pp. 3320-3331
    • Kubota, Y.1    Mimura, S.2    Nishimoto, S.-I.3    Masuda, T.4    Nojima, H.5    Takisawa, H.6
  • 30
    • 33745932545 scopus 로고    scopus 로고
    • An anthropoid-specific segmental duplication on human chromosome 1q22
    • Kuryshev, V. Y., et al. (2006). An anthropoid-specific segmental duplication on human chromosome 1q22. Genomics 88, 143-151.
    • (2006) Genomics , vol.88 , pp. 143-151
    • Kuryshev, V.Y.1
  • 31
    • 0034595448 scopus 로고    scopus 로고
    • Uninterrupted MCH2-7 function required for DNA replication fork progression
    • DOI 10.1126/science.288.5471.1643
    • Labib, K., Tercero, J. A., and Diffley, J. F. (2000). Uninterrupted MCM2-7 function required for DNA replication fork progression. Science 288, 1643-1647. (Pubitemid 30387430)
    • (2000) Science , vol.288 , Issue.5471 , pp. 1643-1647
    • Labib, K.1    Tercero, J.A.2    Diffley, J.F.X.3
  • 32
    • 0027109075 scopus 로고
    • Cancer. p53, guardian of the genome
    • Lane, D. P. (1992). Cancer. p53, guardian of the genome. Nature 358, 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 33
    • 0030612360 scopus 로고    scopus 로고
    • MDM2-arbiter of p53's destruction
    • Lane, D. P., and Hall, P. A. (1997). MDM2-arbiter of p53's destruction. Trends Biochem. Sci. 22, 372-374.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 372-374
    • Lane, D.P.1    Hall, P.A.2
  • 34
    • 0036898541 scopus 로고    scopus 로고
    • Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signaling
    • Langheinrich, U., Hennen, E., Stott, G., and Vacun, G. (2002). Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signaling. Curr. Biol. 12, 2023-2028.
    • (2002) Curr. Biol. , vol.12 , pp. 2023-2028
    • Langheinrich, U.1    Hennen, E.2    Stott, G.3    Vacun, G.4
  • 35
    • 34347408021 scopus 로고    scopus 로고
    • The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development
    • Liu, Y., et al. (2007). The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development. Blood 110, 99-106.
    • (2007) Blood , vol.110 , pp. 99-106
    • Liu, Y.1
  • 36
    • 0034039040 scopus 로고    scopus 로고
    • Dial 9-1-1 for p 53, mechanisms of p53 activation by cellular stress
    • Ljungman, M. (2000). Dial 9-1-1 for p 53, mechanisms of p53 activation by cellular stress. Neoplasia 2, 208-225.
    • (2000) Neoplasia , vol.2 , pp. 208-225
    • Ljungman, M.1
  • 37
    • 4644303124 scopus 로고    scopus 로고
    • Gadd45 proteins induce G2/M arrest and modulate apoptosis in kidney cells exposed to hyperosmotic stress
    • Mak, S. K., and Kultz, D. (2004). Gadd45 proteins induce G2/M arrest and modulate apoptosis in kidney cells exposed to hyperosmotic stress. J. Biol. Chem. 279, 39075-39084.
    • (2004) J. Biol. Chem. , vol.279 , pp. 39075-39084
    • Mak, S.K.1    Kultz, D.2
  • 38
    • 0035339357 scopus 로고    scopus 로고
    • ATM-dependent phosphorylation of Mdm2 on serine 395, role in p53 activation by DNA damage
    • Maya, R., et al. (2001). ATM-dependent phosphorylation of Mdm2 on serine 395, role in p53 activation by DNA damage. Genes Dev. 15, 1067-1077.
    • (2001) Genes Dev. , vol.15 , pp. 1067-1077
    • Maya, R.1
  • 39
    • 0035498938 scopus 로고    scopus 로고
    • Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
    • Melo, J. A., Cohen, J., and Toczyski, D. P. (2001). Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev. 15, 2809-2821. (Pubitemid 33042052)
    • (2001) Genes and Development , vol.15 , Issue.21 , pp. 2809-2821
    • Melo, J.A.1    Cohen, J.2    Toczyski, D.P.3
  • 40
    • 0031961995 scopus 로고    scopus 로고
    • Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: PRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
    • Niculescu, A. B., 3rd, Chen, X., Smeets, M., Hengst, L., Prives, C., and Reed, S. I. (1998). Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol. Cell. Biol. 18, 629-643.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 629-643
    • Niculescu III, A.B.1    Chen, X.2    Smeets, M.3    Hengst, L.4    Prives, C.5    Reed, S.I.6
  • 41
    • 0026596327 scopus 로고
    • Dynamic organization of DNA replication in mammalian cell nuclei: Spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences
    • O'Keefe, R. T., Henderson, S. C., and Spector, D. L. (1992). Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences. J. Cell Biol. 116, 1095-1110.
    • (1992) J. Cell Biol. , vol.116 , pp. 1095-1110
    • O'Keefe, R.T.1    Henderson, S.C.2    Spector, D.L.3
  • 42
    • 5044236667 scopus 로고    scopus 로고
    • A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication
    • DOI 10.1038/sj.emboj.7600369
    • Pacek, M., and Walter, J. C. (2004). A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication. EMBO J. 23, 3667-3676. (Pubitemid 39336288)
    • (2004) EMBO Journal , vol.23 , Issue.18 , pp. 3667-3676
    • Pacek, M.1    Walter, J.C.2
  • 43
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., and Bonner, W. M. (2000). A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10, 886-895.
    • (2000) Curr. Biol. , vol.10 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 44
    • 30844447720 scopus 로고    scopus 로고
    • P53 deficiency rescues apoptosis and differentiation of multiple cell types in zebrafish flathead mutants deficient for zygotic DNA polymerase δ1
    • DOI 10.1038/sj.cdd.4401747, PII 4401747
    • Plaster, N., Sonntag, C., Busse, C. E., and Hammerschmidt, M. (2006). p53 deficiency rescues apoptosis and differentiation of multiple cell types in zebrafish flathead mutants deficient for zygotic DNA polymerase delta1. Cell Death Differ. 13, 223-235. (Pubitemid 43102206)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.2 , pp. 223-235
    • Plaster, N.1    Sonntag, C.2    Busse, C.E.3    Hammerschmidt, M.4
  • 45
    • 6944256712 scopus 로고    scopus 로고
    • Sequence and embryonic expression of three zebrafish fringe genes: Lunatic fringe, radical fringe, and manic fringe
    • DOI 10.1002/dvdy.20155
    • Qiu, X., Xu, H., Haddon, C., Lewis, J., and Jiang, Y.-J. (2004). Sequence and embryonic expression of three zebrafish fringe genes, lunatic fringe, radical fringe, and manic fringe. Dev. Dyn. 231, 621-630. (Pubitemid 39410897)
    • (2004) Developmental Dynamics , vol.231 , Issue.3 , pp. 621-630
    • Qiu, X.1    Xu, H.2    Haddon, C.3    Lewis, J.4    Jiang, Y.-J.5
  • 46
    • 8744233919 scopus 로고    scopus 로고
    • After double-strand break induction by UV-A, homologous recombination and nonhomologous end joining cooperate at the same DSB if both systems are available
    • DOI 10.1242/jcs.01355
    • Rapp, A., and Greulich, K. O. (2004). After double-strand break induction by UV-A, homologous recombination and nonhomologous end joining cooperate at the same DSB if both systems are available. J. Cell Sci. 117, 4935-4945. (Pubitemid 39517510)
    • (2004) Journal of Cell Science , vol.117 , Issue.21 , pp. 4935-4945
    • Rapp, A.1    Greulich, K.O.2
  • 47
    • 0037884963 scopus 로고    scopus 로고
    • Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
    • Rothkamm, K., and Löbrich, M. (2003). Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc. Natl. Acad. Sci. USA 100, 5057-5062.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5057-5062
    • Rothkamm, K.1    Löbrich, M.2
  • 48
    • 29444432956 scopus 로고    scopus 로고
    • Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis
    • Ryu, S., Holzschuh, J., Erhardt, S., Ettl, A. K., and Driever, W. (2005). Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis. Proc. Natl. Acad. Sci. USA 102, 18467-18472.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 18467-18472
    • Ryu, S.1    Holzschuh, J.2    Erhardt, S.3    Ettl, A.K.4    Driever, W.5
  • 49
    • 42249107144 scopus 로고    scopus 로고
    • Wild-type p53 and p73 negatively regulate expression of proliferation related genes
    • Scian, M. J., et al. (2008). Wild-type p53 and p73 negatively regulate expression of proliferation related genes. Oncogene 27, 2583-2593.
    • (2008) Oncogene , vol.27 , pp. 2583-2593
    • Scian, M.J.1
  • 50
    • 8544221940 scopus 로고    scopus 로고
    • DNA unwinding is an Mcm complex-dependent and ATP hydrolysis-dependent process
    • Shechter, D., Ying, C. Y., and Gautier, J. (2004). DNA unwinding is an Mcm complex-dependent and ATP hydrolysis-dependent process. J. Biol. Chem. 279, 45586-45593.
    • (2004) J. Biol. Chem. , vol.279 , pp. 45586-45593
    • Shechter, D.1    Ying, C.Y.2    Gautier, J.3
  • 51
    • 34247874509 scopus 로고    scopus 로고
    • Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies
    • Shi, Y., Dodson, G. E., Mukhopadhyay, P. S., Shanware, N. P., Trinh, A. T., and Tibbetts, R. S. (2007). Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies. J. Biol. Chem. 282, 9236-9243.
    • (2007) J. Biol. Chem. , vol.282 , pp. 9236-9243
    • Shi, Y.1    Dodson, G.E.2    Mukhopadhyay, P.S.3    Shanware, N.P.4    Trinh, A.T.5    Tibbetts, R.S.6
  • 52
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • DOI 10.1016/S0092-8674(00)80416-X
    • Shieh, S. Y., Ikeda, M., Taya, Y., and Prives, C. (1997). DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325-334. (Pubitemid 27467963)
    • (1997) Cell , vol.91 , Issue.3 , pp. 325-334
    • Shieh, S.-Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 53
    • 0035253615 scopus 로고    scopus 로고
    • ATM and ATR: Networking cellular responses to DNA damage
    • Shiloh, Y. (2001). ATM and ATR: networking cellular responses to DNA damage. Curr. Opin. Genet. Dev. 11, 71-77.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 71-77
    • Shiloh, Y.1
  • 54
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh, Y. (2003). ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3, 155-168.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 55
    • 11244271837 scopus 로고    scopus 로고
    • Sin 3, a flexible regulator of global gene expression and genome stability
    • Silverstein, R. A., and Ekwall, K. (2005). Sin 3, a flexible regulator of global gene expression and genome stability. Curr. Genet. 47, 1-17.
    • (2005) Curr. Genet. , vol.47 , pp. 1-17
    • Silverstein, R.A.1    Ekwall, K.2
  • 57
    • 0032881250 scopus 로고    scopus 로고
    • MCM proteins in DNA replication
    • Tye, B. K. (1999). MCM proteins in DNA replication. Annu. Rev. Biochem. 68, 649-686.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 649-686
    • Tye, B.K.1
  • 58
    • 0029922537 scopus 로고    scopus 로고
    • The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21(WAF1/CIP1)
    • Vairapandi, M., Balliet, A. G., Fornace, A. J., Jr., Hoffman, B., and Liebermann, D. A. (1996). The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1. Oncogene 12, 2579-2594. (Pubitemid 26237787)
    • (1996) Oncogene , vol.12 , Issue.12 , pp. 2579-2594
    • Vairapandi, M.1    Balliet, A.G.2    Fornace Jr., A.J.3    Hoffman, B.4    Liebermann, D.A.5
  • 59
    • 0028849274 scopus 로고
    • P21 is necessary for the p53-mediated G1 arrest in human cancer cells
    • Waldman, T., Kinzler, K. W., and Vogelstein, B. (1995). p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 55, 5187-5190.
    • (1995) Cancer Res. , vol.55 , pp. 5187-5190
    • Waldman, T.1    Kinzler, K.W.2    Vogelstein, B.3
  • 60
    • 0025096058 scopus 로고
    • The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs
    • Wang, H., Clark, I., Nicholson, P. R., Herskowitz, I., and Stillman, D. J. (1990). The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs. Mol. Cell. Biol. 10, 5927-5936.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5927-5936
    • Wang, H.1    Clark, I.2    Nicholson, P.R.3    Herskowitz, I.4    Stillman, D.J.5
  • 64
    • 0028121028 scopus 로고
    • A mammalian homologue of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin
    • Wreggett, K. A., Hill, F., James, P. S., Hutchings, A., Butcher, G. W., and Singh, P. B. (1994). A mammalian homologue of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin. Cytogenet. Cell. Genet. 66, 99-103.
    • (1994) Cytogenet. Cell. Genet. , vol.66 , pp. 99-103
    • Wreggett, K.A.1    Hill, F.2    James, P.S.3    Hutchings, A.4    Butcher, G.W.5    Singh, P.B.6
  • 65
    • 43049127158 scopus 로고    scopus 로고
    • Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53
    • DOI 10.1242/dev.011015
    • Yamaguchi, M., Fujimori-Tonou, N., Yoshimura, Y., Kishi, T., Okamoto, H., and Masai, I. (2008). Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53. Development 135, 1247-1257. (Pubitemid 351622469)
    • (2008) Development , vol.135 , Issue.7 , pp. 1247-1257
    • Yamaguchi, M.1    Fujimori-Tonou, N.2    Yoshimura, Y.3    Kishi, T.4    Okamoto, H.5    Masai, I.6
  • 66
    • 0031697445 scopus 로고    scopus 로고
    • Zebrafish paraxial protocadherin is a downstream target of spadetail involved in morphogenesis of gastrula mesoderm
    • Yamamoto, A., Amacher, S. L., Kim, S.-H., Geissert, D., Kimmel, C. B., and De Robertis, E. M. (1998). Zebrafish paraxial protocadherin is a downstream target of spadetail involved in morphogenesis of gastrula mesoderm. Development 125, 3389-3397.
    • (1998) Development , vol.125 , pp. 3389-3397
    • Yamamoto, A.1    Amacher, S.L.2    Kim, S.-H.3    Geissert, D.4    Kimmel, C.B.5    De Robertis, E.M.6
  • 67
    • 11144227916 scopus 로고    scopus 로고
    • Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses
    • Yoo, H. Y., Shevchenko, A., Shevchenko, A., and Dunphy, W. G. (2004). Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses. J. Biol. Chem. 279, 53353-53364.
    • (2004) J. Biol. Chem. , vol.279 , pp. 53353-53364
    • Yoo, H.Y.1    Shevchenko, A.2    Shevchenko, A.3    Dunphy, W.G.4
  • 68
    • 0346752097 scopus 로고    scopus 로고
    • A strategy for constructing large protein interaction maps using the yeast two-hybrid system: Regulated expression arrays and two-phase mating
    • Zhong, J., Zhang, H., Stanyon, C. A., Tromp, G., and Finley, R. L., Jr. (2003). A strategy for constructing large protein interaction maps using the yeast two-hybrid system: regulated expression arrays and two-phase mating. Genome Res. 13, 2691-2699.
    • (2003) Genome Res. , vol.13 , pp. 2691-2699
    • Zhong, J.1    Zhang, H.2    Stanyon, C.A.3    Tromp, G.4    Finley Jr., R.L.5
  • 69
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou, B. B., and Elledge, S. J. (2000). The DNA damage response: putting checkpoints in perspective. Nature 408, 433-439.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.