Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53

Development

Volumn 135, Issue 7, 2008, Pages 1247-1257

  Yamaguchi, Masahiro ^a,b   Fujimori Tonou, Noriko ^b   Yoshimura, Yukihiro ^a   Kishi, Tsutomu ^b   Okamoto, Hitoshi ^c   Masai, Ichiro ^a,b  

^a OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY   (Japan)

^b RIKEN   (Japan)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

Apoptosis; Checkpoint; Chk; Danio rerio; p53; Prim1; Retina; Zebrafish

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 2; DNA PRIMASE; PRIM 1; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FATE; CELL ISOLATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; EMBRYO; GENE ACTIVATION; MISSENSE MUTATION; NERVE CELL DIFFERENTIATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RETINA DEVELOPMENT; RETINA NERVE CELL; RNA SYNTHESIS; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; DNA DAMAGE; DNA PRIMASE; EMBRYO, NONMAMMALIAN; ENZYME ACTIVATION; MODELS, BIOLOGICAL; MUTATION, MISSENSE; NEURONS; PROTEIN-SERINE-THREONINE KINASES; RETINA; TUMOR SUPPRESSOR PROTEIN P53; ZEBRAFISH;

ATAXIA TELANGIECTASIA; DANIO RERIO;

EID: 43049127158     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.011015     Document Type: Article

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