Thioredoxin and its related molecules: Update 2005

Antioxidants and Redox Signaling

Volumn 7, Issue 5-6, 2005, Pages 823-828

  Nakamura, Hajime ^a  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CYSTEINE; THIOREDOXIN; THIOREDOXIN 1; THIOREDOXIN 80; THIOREDOXIN PEROXIDASE; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIINFLAMMATORY ACTIVITY; CELL PROTECTION; CYTOSOL; ENZYME ACTIVE SITE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; SHORT SURVEY; SIGNAL TRANSDUCTION;

ANIMALS; CYSTEINE; HUMANS; OXIDATION-REDUCTION; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; THIOREDOXIN;

EID: 17644395645     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2005.7.823     Document Type: Short Survey

References (71)

1. Bodnar JS, Chatterjee A, Castellani LW, Ross DA, Ohmen J, Cavalcoli J, Wu C, Dains KM, Catanese J, Chu M, Sheth SS, Charugundla K, Demant P, West DB, de Jong P, and Lusis AJ. Positional cloning of the combined hyperlipidemia gene Hyplip1. Nat Genet 30: 110-116, 2002.
2. Casagrande S, Bonetto V, Fratelli M, Gianazza E, Eberini I, Massignan T, Salmona M, Chang G, Holmgren A, and Ghezzi P. Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems. Proc Natl Acad Sci USA 99: 9745-9749, 2002.
3. Cunnea PM, Miranda-Vizuete A, Bertoli G, Simmen T, Damdimopoulos AE, Hermann S, Leinonen S, Huikko MP, Gustafsson JA, Sitia R, and Spyrou G. ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress. J Biol Chem 278: 1059-1066, 2003.
4. Das DK. Thioredoxin regulation of ischemic preconditioning. Antioxid Redox Signal 6: 405-412, 2004.
5. Das KC. Thioredoxin system in premature and newborn biology. Antioxid Redox Signal 6: 177-184, 2004.
6. Fernandes AP and Holmgren A. Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system. Antioxid Redox Signal 6: 63-74, 2004.
7. Haendeler J, Hoffmann J, Tischler V, Berk BC, Zeiher AM, and Dimmeler S. Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69. Nat Cell Biol 4: 743-749, 2002.
8. Haendeler J, Hoffmann J, Zeiher AM, and Dimmeler S. Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins. Circulation 110: 856-861, 2004.
9. Hattori I, Takagi Y, Nakamura H, Nozaki K, Bai J, Kondo N, Sugino T, Nishimura M, Hashimoto N, and Yodoi J. Intravenous administration of thioredoxin decreases brain damage following transient focal cerebral ischemia in mice. Antioxid Redox Signal 6: 81-87, 2004.
10. Hirota K, Matsui M, Iwata S, Nishiyama A, Mori K, and Yodoi J. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc Natl Acad Sci U S A 94: 3633-3638, 1997.
11. Hirota K, Murata M, Sachi Y, Nakamura H, Takeuchi J, Mori K, and Yodoi J. Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB. J Biol Chem 274: 27891-27897, 1999.
12. Hirota K, Nakamura H, Arai T, Ishii H, Bai J, Itoh T, Fukuda K, and Yodoi J. Geranylgeranylacetone enhances expression of thioredoxin and suppresses ethanol-induced cytotoxicity in cultured hepatocytes. Biochem Biophys Res Commun 275: 825-830, 2000.
13. Hoshino T, Nakamura H, Okamoto M, Kato S, Araya S, Nomiyama K, Oizumi K, Young HA, Aizawa H, and Yodoi J. Redox-active protein thioredoxin prevents proinflammatory cytokine- or bleomycin-induced lung injury. Am J Respir Crit Care Med 168: 1075-1083, 2003.
14. Hosoda A, Kimata Y, Tsuru A, and Kohno K. JPDI, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs. J Biol Chem 278: 2669-2676, 2003.
15. Jeong W, Chang TS, Boja ES, Fales HM, and Rhee SG. Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways. J Biol Chem 279: 3151-3159, 2004.
16. Jeong W, Yoon HW, Lee SR, and Rhee SG. Identification and characterization of TRP14, a thioredoxin-related protein of 14 kDa. New insights into the specificity of thioredoxin function. J Biol Chem 279: 3142-3150, 2004.
17. Jimenez A, Zu W, Rawe VY, Pelto-Huikko M, Flickinger CJ, Sutovsky P, Gustafsson JA, Oko R, and Miranda-Vizuete A. Spermatocyte/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis. J Biol Chem 279: 34971-34982, 2004.
18. Johansson C, Lillig CH, and Holmgren A. Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase. J Biol Chem 279: 7537-7543, 2004.
19. Kasuno K, Nakamura H, Ono T, Muso E, and Yodoi J. Protective roles of thioredoxin, a redox-regulating protein, in renal ischemia/reperfusion injury. Kidney Int 64: 1273-1282, 2003.
20. Kishimoto C, Shioji K, Nakamura H, Nakayama Y, Yodoi J, and Sasayama S. Serum thioredoxin (TRX) levels in patients with heart failure. Jpn Circ J 65: 491-494, 2001.
21. Kleemann R, Kapurniotu A, Mischke R, Held J, and Bernhagen J. Characterization of catalytic centre mutants of macrophage migration inhibitory factor (MIF) and comparison to Cys81 Ser MIF. Eur J Biochem 261: 753-766, 1999.
22. Kondo N, Ishii Y, Kwon YW, Tanito M, Horita H, Nishinaka Y, Nakamura H, and Yodoi J. Redox-sensing release of human thioredoxin from T lymphocytes with negative feedback loops. J Immunol 172: 442-448, 2004.
23. 2. J Biol Chem 277: 20336-20342, 2002.
24. Lee TH, Kim SU, Yu SL, Kim SH, Park do S, Moon HB, Dho SH, Kwon KS, Kwon HJ, Han YH, Jeong S, Kang SW, Shin HS, Lee KK, Rhee SG, and Yu DY. Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice. Blood 101: 5033-5038, 2003.
25. Lillig CH, Lonn ME, Enoksson M, Fernandes AP, and Holmgren A. Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide. Proc Natl Acad Sci U S A 101: 13227-13232, 2004.
26. Liu W, Nakamura H, Shioji K, Tanito M, Oka SI, Ahsan MK, Son A, Ishii Y, Kishimoto C, and Yodoi J. Thioredoxin-1 ameliorates myosin-induced autoimmune myocarditis by suppressing chemokine expressions and leukocyte chemotaxis in mice. Circulation 110: 1276-1283, 2004.
27. Lowenstein CJ. Exogenous thioredoxin reduces inflammation in autoimmune myocarditis. Circulation 110: 1178-1179, 2004.
28. Lundberg M, Johansson C, Chandra J, Enoksson M, Jacobsson G, Ljung J, Johansson M, and Holmgren A. Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms. J Biol Chem 276: 26269-26275, 2001.
29. Mahmood S, Kawanaka M, Kamei A, Izumi A, Nakata K, Niiyama G, Ikeda H, Hanano S, Suehiro M, Togawa K, and Yamada G. Immunohistochemical evaluation of oxidative stress markers in chronic hepatitis C. Antioxid Redox Signal 6: 19-24, 2004.
30. Matsui M, Oshima M, Oshima H, Takaku K, Maruyama T, Yodoi J, and Taketo MM. Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. Dev Biol 178: 179-185, 1996.
31. Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, and Kizaka-Kondoh S. Identification of a novel thioredoxin-related transmembrane protein. J Biol Chem 276: 10032-10038, 2001.
32. Matsuo Y, Nishinaka Y, Suzuki S, Kojima M, Kizaka-Kondoh S, Kondo N, Son A, Sakakura-Nishiyama J, Yamaguchi Y, Masutani H, Ishii Y, and Yodoi J. TMX, a human transmembrane oxidoreductase of the thioredoxin family: the possible role in disulfide-linked protein folding in the endoplasmic reticulum. Arch Biochem Biophys 423: 81-87, 2004.
33. Matsuzawa A, Nishitoh H, Tobiume K, Takeda K, and Ichijo H. Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice. Antioxid Redox Signal 4: 415-425, 2002.
34. Matthias LJ and Hogg PJ. Redox control on the cell surface: implications for HIV-1 entry. Antioxid Redox Signal 5: 133-138, 2003.
35. Miranda-Vizuete A, Sadek CM, Jimenez A, Krause WJ, Sutovsky P, and Oko R. The mammalian testis-specific thioredoxin system. Antioxid Redox Signal 6: 25-40, 2004.
36. Mitsui A, Hamuro J, Nakamura H, Kondo N, Hirabayashi Y, Ishizaki-Koizumi S, Hirakawa T, Inoue T, and Yodoi J. Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span. Antioxid Redox Signal 4: 693-696, 2002.
37. Miyamoto S, Kawano H, Sakamoto T, Soejima H, Kajiwara I, Hokamaki J, Hirai N, Sugiyama S, Yoshimura M, Yasue H, Nakamura H, Yodoi J, and Ogawa H. Increased plasma levels of thioredoxin in patients with coronary spastic angina. Antioxid Redox Signal 6: 75-80, 2004.
38. Miyamoto S, Kawano H, Takazoe K, Soejima H, Sakamoto T, Hokamaki J, Yoshimura M, Nakamura H, Yodoi J, and Ogawa H. Vitamin E improves fibrinolytic activity in patients with coronary spastic angina. Thromb Res 113: 345-351, 2004.
39. Murata H, Ihara Y, Nakamura H, Yodoi J, Sumikawa K, and Kondo T. Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt. J Biol Chem 278: 50226-50233, 2003.
40. Nakamura H. Thioredoxin as a key molecule in redox signaling. Antioxid Redox Signal 6: 15-17, 2004.
41. Nakamura H, De Rosa SC, Yodoi J, Holmgren A, Ghezzi P, and Herzenberg LA. Chronic elevation of plasma thioredoxin: inhibition of chemotaxis and curtailment of life expectancy in AIDS. Proc Natl Acad Sci USA 98: 2688-2693, 2001.
42. Nakamura H, Herzenberg LA, Bai J, Araya S, Kondo N, Nishinaka Y, and Yodoi J. Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis. Proc Natl Acad Sci U S A 98: 15143-15148, 2001.
43. Nakamura H, Masutani H, and Yodoi J. Redox imbalance and its control in HIV infection. Antioxid Redox Signal 4: 455-464, 2002.
44. Nakamura H, Tamura S, Watanabe I, Iwasaki T, and Yodoi J. Enhanced resistancy of thioredoxin-transgenic mice against influenza virus-induced pneumonia. Immunol Lett 82: 165-170, 2002.
45. Neumann CA, Krause DS, Carman CV, Das S, Dubey DP, Abraham JL, Bronson RT, Fujiwara Y, Orkin SH, and Van Etten RA. Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression. Nature 424: 561-565, 2003.
46. Nishinaka Y, Nishiyama A, Masutani H, Oka S, Ahsan KM, Nakayama Y, Ishii Y, Nakamura H, Maeda M, and Yodoi J. Loss of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 in human T-cell leukemia virus type I-dependent T-cell transformation: implications for adult T-cell leukemia leukemogenesis. Cancer Res 64: 1287-1292, 2004.
47. Nonn L, Williams RR, Erickson RP, and Powis G. The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice. Mol Cell Biol 23: 916-922, 2003.
48. Okuyama H, Nakamura H, Shimahara Y, Araya S, Kawada N, Yamaoka Y, and Yodoi J. Overexpression of thioredoxin prevents acute hepatitis caused by thioacetamide or lipopolysaccharide in mice. Hepatology 37: 1015-1025, 2003.
49. Pekkari K and Holmgren A. Truncated thioredoxin: physiological functions and mechanism. Antioxid Redox Signal 6: 53-61, 2004.
50. Rundlof AK and Arner ES. Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events. Antioxid Redox Signal 6: 41-52, 2004.
51. Sadek CM, Jimenez A, Damdimopoulos AE, Kieselbach T, Nord M, Gustafsson JA, Spyrou G, Davis EC, Oko R, van der Hoorn FA, and Miranda-Vizuete A. Characterization of human thioredoxin-like 2. A novel microtubule-binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme. J Biol Chem 278: 13133-13142, 2003.
52. Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, and Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 17: 2596-2606, 1998.
53. Shibata T, Yamada T, Ishii T, Kumazawa S, Nakamura H, Masutani H, Yodoi J, and Uchida K. Thioredoxin as a molecular target of cyclopentenone prostaglandins. J Biol Chem 278: 26046-26054, 2003.
54. Shioji K, Kishimoto C, Nakamura H, Masutani H, Yuan Z, Oka S, and Yodoi J. Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity. Circulation 106: 1403-1409, 2002.
55. Shioji K, Nakamura H, Masutani H, and Yodoi J. Redox regulation by thioredoxin in cardiovascular diseases. Antioxid Redox Signal 5: 795-802, 2003.
56. Sumida Y, Nakashima T, Yoh T, Nakajima Y, Ishikawa H, Mitsuyoshi H, Sakamoto Y, Okanoue T, Kashima K, Nakamura H, and Yodoi J. Serum thioredoxin levels as an indicator of oxidative stress in patients with hepatitis C virus infection. J Hepatol 33: 616-622, 2000.
57. Sumida Y, Nakashima T, Yoh T, Furutani M, Hirohama A, Kakisaka Y, Nakajima Y, Ishikawa H, Mitsuyoshi H, Okanoue T, Kashima K, Nakamura H, and Yodoi J. Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease. J Hepatol 38: 32-38, 2003.
58. Sun QA, Kirnarsky L, Sherman S, and Gladyshev VN. Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems. Proc Natl Acad Sci U S A 98: 3673-3678, 2001.
59. Sun QA, Zappacosta F, Factor VM, Wirth PJ, Hatfield DL, and Gladyshev VN. Heterogeneity within animal thioredoxin reductases. Evidence for alternative first exon splicing. J Biol Chem 276: 3106-3114, 2001.
60. Takagi Y, Mitsui A, Nishiyama A, Nozaki K, Sono H, Gon Y, Hashimoto N, and Yodoi J. Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage. Proc Natl Acad Sci U S A 96: 4131-4136, 1999.
61. Tanaka T, Hosoi F, Yamaguchi-Iwai Y, Nakamura H, Masutani H, Ueda S, Nishiyama A, Takeda S, Wada H, Spyrou G, and Yodoi J. Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis. EMBO J 21: 1695-1703, 2002.
62. Tanito M, Masutani H, Nakamura H, Oka S, Ohira A, and Yodoi J. Attenuation of retinal photooxidative damage in thioredoxin transgenic mice. Neurosci Lett 326: 142-146, 2002.
63. Tanito M, Nakamura H, Kwon YW, Teratani A, Masutani H, Shioji K, Kishimoto C, Ohira A, Horie R, and Yodoi J. Enhanced oxidative stress and impaired thioredoxin expression in spontaneously hypertensive rats. Antioxid Redox Signal 6: 89-97, 2004.
64. Tao L, Gao E, Bryan NS, Qu Y, Liu HR, Hu A, Christopher TA, Lopez BL, Yodoi J, Koch WJ, Feelisch M, and Ma XL. Cardioprotective effects of thioredoxin in myocardial ischemia and the reperfusion role of S-nitrosation. Proc Natl Acad Sci U S A 101: 11471-11476, 2004.
65. Ueda S, Masutani H, Nakamura H, Tanaka T, Ueno M, and Yodoi J. Redox control of cell death. Antioxid Redox Signal 4: 405-414, 2002.
66. Ueno M, Masutani H, Arai RJ, Yamauchi A, Hirota K, Sakai T, Inamoto T, Yamaoka Y, Yodoi J, and Nikaido T. Thioredoxin-dependent redox regulation of p53-mediated p21 activation. J Biol Chem 274: 35809-35815, 1999.
67. Watarai H, Nozawa R, Tokunaga A, Yuyama N, Tomas M, Hinohara A, Ishizaka K, and Ishii Y. Posttranslational modification of the glycosylation inhibiting factor (GIF) gene product generates bioactive GIF. Proc Natl Acad Sci U S A 97: 13251-13256, 2000.
68. Watson WH, Pohl J, Montfort WR, Stuchlik O, Reed MS, Powis G, and Jones DP. Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif. J Biol Chem 278: 33408-33415, 2003.
69. Wrammert J, Kallberg E, and Leanderson T. Identification of a novel thioredoxin-related protein, PC-TRP, which is preferentially expressed in plasma cells. Eur J Immunol 34: 137-146, 2004.
70. Yoshida T, Oka S, Masutani H, Nakamura H, and Yodoi J. The role of thioredoxin in the aging process: involvement of oxidative stress. Antioxid Redox Signal 5: 563-570, 2003.
71. Zhao R and Holmgren A. Ebselen is a dehydroascorbate reductase mimic, facilitating the recycling of ascorbate via mammalian thioredoxin systems. Antioxid Redox Signal 6: 99-104, 2004.