메뉴 건너뛰기




Volumn 8, Issue 20, 2009, Pages 3328-3339

Alphavirus M1 induces apoptosis of malignant glioma cells via downregulation and nucleolar translocation of p21WAF1/CIP1 protein

Author keywords

Alphavirus; Apoptosis; Caspase; CDK2; NPM; Nucleolar translocation; p21; S phase

Indexed keywords

CASPASE 3; CELL CYCLE PROTEIN; CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 2 INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLINE; LACTATE DEHYDROGENASE; NUCLEOPHOSMIN; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL 2; ROSCOVITINE;

EID: 70350217760     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.20.9832     Document Type: Article
Times cited : (44)

References (79)
  • 1
    • 34247229096 scopus 로고    scopus 로고
    • Exogenous wt-p53 enhances the antitumor effect of HSV-TK/GCV on C6 glioma cells
    • DOI 10.1007/s11060-006-9279-x
    • Huang Q, Pu P, Xia Z, You Y. Exogenous wt-p53 enhances the antitumor effect of HSV-TK/GCV on C6 glioma cells. J Neurooncol 2007; 82:239-248 (Pubitemid 46614385)
    • (2007) Journal of Neuro-Oncology , vol.82 , Issue.3 , pp. 239-248
    • Huang, Q.1    Pu, P.2    Xia, Z.3    You, Y.4
  • 2
    • 0032948143 scopus 로고    scopus 로고
    • Attenuation of WAF1/Cip1 expression by an antisense adenovirus expression vector sensitizes glioblastoma cells to apoptosis induced by chemotherapeutic agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin
    • Ruan S, Okcu MF, Pong RC, Andreeff M, Levin V, Hsieh JT, et al. Attenuation of WAF1/Cip1 expression by an antisense adenovirus expression vector sensitizes glioblastoma cells to apoptosis induced by chemotherapeutic agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin. Clin Cancer Res 1999; 5:197-202. (Pubitemid 29045194)
    • (1999) Clinical Cancer Research , vol.5 , Issue.1 , pp. 197-202
    • Ruan, S.1    Okcu, M.F.2    Pong, R.-C.3    Andreeff, M.4    Levin, V.5    Hsieh, J.-T.6    Zhang, W.7
  • 3
    • 0035872405 scopus 로고    scopus 로고
    • Inactivation of p53 sensitizes U87MG glioma cells to 1,3-bis(2- chloroethyl)1-nitrosourea
    • Xu GW, Nutt CL, Zlatescu MC, Keeney M, Chin-Yee I, Cairncross JG. Inactivation of p53 sensitizes U87MG glioma cells to 1,3-bis(2-chloroethyl)-1- nitrosourea. Cancer Res 2001; 61:4155-4159 (Pubitemid 32720984)
    • (2001) Cancer Research , vol.61 , Issue.10 , pp. 4155-4159
    • Xu, G.W.1    Nutt, C.L.2    Zlatescu, M.C.3    Keeney, M.4    Chin-Yee, I.5    Cairncross, J.G.6
  • 4
    • 0034045930 scopus 로고    scopus 로고
    • Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression
    • DOI 10.1128/MCB.20.13.4580-4590.2000
    • Besson A, Yong VW. Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression. Mol Cell Biol 2000; 20:4580-4590 (Pubitemid 30396106)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.13 , pp. 4580-4590
    • Besson, A.1    Yong, V.W.2
  • 5
    • 0034738420 scopus 로고    scopus 로고
    • p21(WAF1/Cip1): More than a break to the cell cycle?
    • Dotto GP. p21(WAF1/Cip1): more than a break to the cell cycle? Biochim Biophys Acta 2000; 1471:43-56.
    • (2000) Biochim Biophys Acta , vol.1471 , pp. 43-56
    • Dotto, G.P.1
  • 6
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • DOI 10.1038/nature05236, PII NATURE05236
    • Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006; 444:756-760 (Pubitemid 44949604)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6    Dewhirst, M.W.7    Bigner, D.D.8    Rich, J.N.9
  • 8
    • 25144436834 scopus 로고    scopus 로고
    • Gene therapy for malignant glioma: Current clinical status
    • DOI 10.1016/j.ymthe.2005.07.357, PII S1525001605010798
    • Pulkkanen KJ, Yla-Herttuala S. Gene therapy for malignant glioma: current clinical status. Mol Ther 2005; 12:585-598 (Pubitemid 41350140)
    • (2005) Molecular Therapy , vol.12 , Issue.4 , pp. 585-598
    • Pulkkanen, K.J.1    Yla-Herttuala, S.2
  • 9
    • 0026628752 scopus 로고
    • High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells
    • Wang KS, Kuhn RJ, Strauss EG, Ou S, Strauss JH. High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells. J Virol 1992; 66:4992-5001.
    • (1992) J Virol , vol.66 , pp. 4992-5001
    • Wang, K.S.1    Kuhn, R.J.2    Strauss, E.G.3    Ou, S.4    Strauss, J.H.5
  • 11
    • 13644257013 scopus 로고    scopus 로고
    • Gene therapy for malignant glioma using Sindbis vectors expressing a fusogenic membrane glycoprotein
    • DOI 10.1002/jgm.605
    • Zhang J, Frolov I, Russell SJ. Gene therapy for malignant glioma using Sindbis vectors expressing a fusogenic membrane glycoprotein. J Gene Med 2004; 6:1082-1091 (Pubitemid 40228121)
    • (2004) Journal of Gene Medicine , vol.6 , Issue.10 , pp. 1082-1091
    • Zhang, J.1    Frolov, I.2    Russell, S.J.3
  • 12
    • 0042063604 scopus 로고    scopus 로고
    • Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene - A phase I/II clinical protocol
    • DOI 10.1023/A:1024979103780
    • Ren H, Boulikas T, Lundstrom K, Soling A, Warnke PC, Rainov NG. Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene - a phase I/ II clinical protocol. J Neurooncol 2003; 64:147-154 (Pubitemid 36992469)
    • (2003) Journal of Neuro-Oncology , vol.64 , Issue.1-2 , pp. 147-154
    • Ren, H.1    Boulikas, T.2    Soling, A.3    Warnke, P.C.4    Rainov, N.G.5
  • 13
    • 0031034802 scopus 로고    scopus 로고
    • bcl-2 acts early to restrict Semliki Forest virus replication and delays virus-induced programmed cell death
    • Scallan MF, Allsopp TE, Fazakerley JK. bcl-2 acts early to restrict Semliki Forest virus replication and delays virus-induced programmed cell death. J Virol 1997; 71:1583-1590
    • (1997) J Virol , vol.71 , pp. 1583-1590
    • Scallan, M.F.1    Allsopp, T.E.2    Fazakerley, J.K.3
  • 16
    • 0033602033 scopus 로고    scopus 로고
    • Two posttranscriptional pathways that regulate p21(Cip1/Waf1/Sdi1) are identified by HPV16-E6 interaction and correlate with life span and cellular senescence
    • DOI 10.1006/excr.1998.4345
    • Burkhart BA, Alcorta DA, Chiao C, Isaacs JS, Barrett JC. Two posttranscriptional pathways that regulate p21(Cip1/Waf1/Sdi1) are identified by HPV16-E6 interaction and correlate with life span and cellular senescence. Exp Cell Res 1999; 247:168-175 (Pubitemid 29393973)
    • (1999) Experimental Cell Research , vol.247 , Issue.1 , pp. 168-175
    • Burkhart, B.A.1    Alcorta, D.A.2    Chiao, C.3    Isaacs, J.S.4    Barrett, J.C.5
  • 17
    • 0034083920 scopus 로고    scopus 로고
    • Lytic infection by double-strand DNA viruses and cell cycle alterations
    • Marechal V, Piolot T. Lytic infection by double-strand DNA viruses and cell cycle alterations. Pathol Biol (Paris) 2000; 48:289-300. (Pubitemid 30318129)
    • (2000) Pathologie Biologie , vol.48 , Issue.3 , pp. 289-300
    • Marechal, V.1    Piolot, T.2
  • 18
    • 0034123695 scopus 로고    scopus 로고
    • A carboxy-terminally truncated form of the human immunodeficiency virus type 1 Vpr protein induces apoptosis via G(1) cell cycle arrest
    • Nishizawa M, Kamata M, Katsumata R, Aida Y. A carboxy-terminally truncated form of the human immunodeficiency virus type 1 Vpr protein induces apoptosis via G(1) cell cycle arrest. J Virol 2000; 74:6058-6067
    • (2000) J Virol , vol.74 , pp. 6058-6067
    • Nishizawa, M.1    Kamata, M.2    Katsumata, R.3    Aida, Y.4
  • 19
    • 24044530420 scopus 로고    scopus 로고
    • G0/G1 arrest and apoptosis induced by SARS-CoV 3b protein in transfected cells
    • DOI 10.1186/1743-422X-2-66
    • Yuan X, Shan Y, Zhao Z, Chen J, Cong Y. G0/G1 arrest and apoptosis induced by SARS-CoV 3b protein in transfected cells. Virol J 2005; 2:66. (Pubitemid 41215515)
    • (2005) Virology Journal , vol.2 , pp. 66
    • Yuan, X.1    Shan, Y.2    Zhao, Z.3    Chen, J.4    Cong, Y.5
  • 20
    • 0034666277 scopus 로고    scopus 로고
    • Differential expression of p53 and p21 in low grade cervical squamous intraepithelial lesions infected with low, intermediate, and high risk human papillomaviruses
    • DOI 10.1002/1097-0142(20000915)89:6<1300::AID-CNCR15>3.0.CO;2-U
    • Giannoudis A, Herrington CS. Differential expression of p53 and p21 in low grade cervical squamous intraepithelial lesions infected with low, intermediate and high risk human papillomaviruses. Cancer 2000; 89:1300-1307 (Pubitemid 30707449)
    • (2000) Cancer , vol.89 , Issue.6 , pp. 1300-1307
    • Giannoudis, A.1    Herrington, C.S.2
  • 21
    • 0032474904 scopus 로고    scopus 로고
    • 1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage
    • Bissonnette N, Hunting DJ. p21-induced cycle arrest in G1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage. Oncogene 1998; 16:3461-3469 (Pubitemid 28349689)
    • (1998) Oncogene , vol.16 , Issue.26 , pp. 3461-3469
    • Bissonnette, N.1    Hunting, D.J.2
  • 22
    • 0033621560 scopus 로고    scopus 로고
    • P21(WAF1/CIP1) Antisense therapy radiosensitizes human colon cancer by converting growth arrest to apoptosis
    • Tian H, Wittmack EK, Jorgensen TJ. p21WAF1/CIP1 antisense therapy radiosensitizes human colon cancer by converting growth arrest to apoptosis. Cancer Res 2000; 60:679-684 (Pubitemid 30094567)
    • (2000) Cancer Research , vol.60 , Issue.3 , pp. 679-684
    • Tian, H.1    Wittmack, E.K.2    Jorgensen, T.J.3
  • 23
    • 0035821788 scopus 로고    scopus 로고
    • P21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents
    • DOI 10.1038/sj.onc.1204440
    • Mahyar-Roemer M, Roemer K. p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. Oncogene 2001; 20:3387-3398 (Pubitemid 32588987)
    • (2001) Oncogene , vol.20 , Issue.26 , pp. 3387-3398
    • Mahyar-Roemer, M.1    Roemer, K.2
  • 24
    • 35548996392 scopus 로고    scopus 로고
    • Genomic analysis of a Chinese isolate of Getah-like virus and its phylogenetic relationship with other Alphaviruses
    • DOI 10.1007/s11262-007-0110-3
    • Wen JS, Zhao WZ, Liu JW, Zhou H, Tao JP, Yan HJ, et al. Genomic analysis of a Chinese isolate of Getahlike virus and its phylogenetic relationship with other Alphaviruses. Virus Genes 2007; 35:597-603. (Pubitemid 350012751)
    • (2007) Virus Genes , vol.35 , Issue.3 , pp. 597-603
    • Wen, J.-S.1    Zhao, W.-Z.2    Liu, J.-W.3    Zhou, H.4    Tao, J.-P.5    Yan, H.-J.6    Liang, Y.7    Zhou, J.-J.8    Jiang, L.-F.9
  • 25
  • 26
    • 0030011128 scopus 로고    scopus 로고
    • Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
    • DOI 10.1038/381713a0
    • Waldman T, Lengauer C, Kinzler KW, Vogelstein B. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 1996; 381:713-716 (Pubitemid 26196573)
    • (1996) Nature , vol.381 , Issue.6584 , pp. 713-716
    • Waldman, T.1    Lengauer, C.2    Kinzler, K.W.3    Vogelstein, B.4
  • 27
    • 34548036682 scopus 로고    scopus 로고
    • Cells with defective p53-p21-pRb pathway are susceptible to apoptosis induced by p84N5 via caspase-6
    • DOI 10.1158/0008-5472.CAN-07-0334
    • Garner E, Martinon F, Tschopp J, Beard P, Raj K. Cells with defective p53-p21-pRb pathway are susceptible to apoptosis induced by p84N5 via caspase-6. Cancer Res 2007; 67:7631-7637 (Pubitemid 47281355)
    • (2007) Cancer Research , vol.67 , Issue.16 , pp. 7631-7637
    • Garner, E.1    Martinon, F.2    Tschopp, J.3    Beard, P.4    Raj, K.5
  • 28
    • 40549111934 scopus 로고    scopus 로고
    • Protective mechanisms of p53-p21-pRb proteins against DNA damage-induced cell death
    • Garner E, Raj K. Protective mechanisms of p53-p21-pRb proteins against DNA damage-induced cell death. Cell Cycle 2008; 7:277-282
    • (2008) Cell Cycle , vol.7 , pp. 277-282
    • Garner, E.1    Raj, K.2
  • 29
    • 0025328320 scopus 로고
    • Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin
    • DOI 10.1038/346534a0
    • Tsurimoto T, Melendy T, Stillman B. Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin. Nature 1990; 346:534-539 (Pubitemid 20238801)
    • (1990) Nature , vol.346 , Issue.6284 , pp. 534-539
    • Tsurimoto, T.1    Melendy, T.2    Stillman, B.3
  • 30
    • 0031469142 scopus 로고    scopus 로고
    • Putting it all together: Building a prereplicative complex
    • DOI 10.1016/S0092-8674(00)80459-6
    • Newlon CS. Putting it all together: building a prereplicative complex. Cell 1997; 91:717-720 (Pubitemid 28007728)
    • (1997) Cell , vol.91 , Issue.6 , pp. 717-720
    • Newlon, C.S.1
  • 31
    • 67649392329 scopus 로고    scopus 로고
    • Anesthetic pentobarbital inhibits proliferation and migration of malignant glioma cells
    • Xie J, Li Y, Huang Y, Qiu P, Shu M, Zhu W, et al. Anesthetic pentobarbital inhibits proliferation and migration of malignant glioma cells. Cancer Lett 2009.
    • (2009) Cancer Lett
    • Xie, J.1    Li, Y.2    Huang, Y.3    Qiu, P.4    Shu, M.5    Zhu, W.6
  • 32
    • 33645231619 scopus 로고    scopus 로고
    • Cyclin D1 overexpression increases the susceptibility of human U266 myeloma cells to CDK inhibitors through a process involving p130-, p107- And E2F-dependent S phase entry
    • Dai Y, Hamm TE, Dent P, Grant S. Cyclin D1 overexpression increases the susceptibility of human U266 myeloma cells to CDK inhibitors through a process involving p130-, p107- and E2F-dependent S phase entry. Cell Cycle 2006; 5:437-446
    • (2006) Cell Cycle , vol.5 , pp. 437-446
    • Dai, Y.1    Hamm, T.E.2    Dent, P.3    Grant, S.4
  • 33
    • 0029147732 scopus 로고
    • Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase
    • Aprelikova O, Xiong Y, Liu ET. Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase. J Biol Chem 1995; 270:18195-18197
    • (1995) J Biol Chem , vol.270 , pp. 18195-18197
    • Aprelikova, O.1    Xiong, Y.2    Liu, E.T.3
  • 34
    • 34147099107 scopus 로고    scopus 로고
    • Autocatalytic phosphorylation of CDK2 at the activating Thr160
    • Abbas T, Jha S, Sherman NE, Dutta A. Autocatalytic phosphorylation of CDK2 at the activating Thr160. Cell Cycle 2007; 6:843-852 (Pubitemid 46572627)
    • (2007) Cell Cycle , vol.6 , Issue.7 , pp. 843-852
    • Abbas, T.1    Jha, S.2    Sherman, N.E.3    Dutta, A.4
  • 35
    • 30044440857 scopus 로고    scopus 로고
    • Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress
    • DOI 10.1091/mbc.E05-07-0594
    • Rodriguez R, Meuth M. Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress. Mol Biol Cell 2006; 17:402-412 (Pubitemid 43049492)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.1 , pp. 402-412
    • Rodriguez, R.1    Meuth, M.2
  • 36
    • 33750494172 scopus 로고    scopus 로고
    • PP2Cgamma-mediated S phase accumulation induced by the proteasome-dependent degradation of p21(WAF1/CIP1)
    • Suh EJ, Kim TY, Kim SH. PP2Cgamma-mediated S phase accumulation induced by the proteasome-dependent degradation of p21(WAF1/CIP1). FEBS Lett 2006; 580:6100-6104
    • (2006) FEBS Lett , vol.580 , pp. 6100-6104
    • Suh, E.J.1    Kim, T.Y.2    Kim, S.H.3
  • 38
    • 0033104495 scopus 로고    scopus 로고
    • Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
    • Asada M, Yamada T, Ichijo H, Delia D, Miyazono K, Fukumuro K, et al. Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation. EMBO J 1999; 18:1223-1234 (Pubitemid 29110307)
    • (1999) EMBO Journal , vol.18 , Issue.5 , pp. 1223-1234
    • Asada, M.1    Yamada, T.2    Ichijo, H.3    Delia, D.4    Miyazono, K.5    Fukumuro, K.6    Mizutani, S.7
  • 39
    • 0033521925 scopus 로고    scopus 로고
    • Caspase 3 inactivation to suppress Fas-mediated apoptosis: Identification of binding domain with p21 and ILP and inactivation machinery by p21
    • DOI 10.1038/sj.onc.1202409
    • Suzuki A, Tsutomi Y, Miura M, Akahane K. Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21. Oncogene 1999; 18:1239-1244 (Pubitemid 29085997)
    • (1999) Oncogene , vol.18 , Issue.5 , pp. 1239-1244
    • Suzuki, A.1    Tsutomi, Y.2    Miura, M.3    Akahane, K.4
  • 40
    • 0035816633 scopus 로고    scopus 로고
    • The Nucleolar Phosphoprotein B23 Interacts with Hepatitis Delta Antigens and Modulates the Hepatitis Delta Virus RNA Replication
    • DOI 10.1074/jbc.M010087200
    • Huang WH, Yung BY, Syu WJ, Lee YH. The nucleolar phosphoprotein B23 interacts with hepatitis delta antigens and modulates the hepatitis delta virus RNA replication. J Biol Chem 2001; 276:25166-25175 (Pubitemid 37412998)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.27 , pp. 25166-25175
    • Huang, W.-H.1    Yung, B.Y.M.2    Syu, W.-J.3    Lee, Y.-H.W.4
  • 41
    • 0030910338 scopus 로고    scopus 로고
    • Nucleolar protein B23 stimulates nuclear import of the HIV-1 Rev protein and NLS-conjugated albumin
    • DOI 10.1021/bi9627931
    • Szebeni A, Mehrotra B, Baumann A, Adam SA, Wingfield PT, Olson MO. Nucleolar protein B23 stimulates nuclear import of the HIV-1 Rev protein and NLS-conjugated albumin. Biochemistry 1997; 36:3941-3949 (Pubitemid 27154715)
    • (1997) Biochemistry , vol.36 , Issue.13 , pp. 3941-3949
    • Szebeni, A.1    Mehrotra, B.2    Baumann, A.3    Adam, S.A.4    Wingfield, P.T.5    Olson, M.O.J.6
  • 42
    • 0033839318 scopus 로고    scopus 로고
    • Physiological significance of apoptosis in animal virus infection
    • DOI 10.1016/S1286-4579(00)01265-X
    • Koyama AH, Fukumori T, Fujita M, Irie H, Adachi A. Physiological significance of apoptosis in animal virus infection. Microbes Infect 2000; 2:1111-1117 (Pubitemid 30664225)
    • (2000) Microbes and Infection , vol.2 , Issue.9 , pp. 1111-1117
    • Koyama, A.H.1    Fukumori, T.2    Fujita, M.3    Irie, H.4    Adachi, A.5
  • 44
    • 0035094982 scopus 로고    scopus 로고
    • Host defense, viruses and apoptosis
    • Barber GN. Host defense, viruses and apoptosis. Cell Death Differ 2001; 8:113-126
    • (2001) Cell Death Differ , vol.8 , pp. 113-126
    • Barber, G.N.1
  • 45
    • 0027532285 scopus 로고
    • Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene
    • DOI 10.1038/361739a0
    • Levine B, Huang Q, Isaacs JT, Reed JC, Griffin DE, Hardwick JM. Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature 1993; 361:739-742 (Pubitemid 23070484)
    • (1993) Nature , vol.361 , Issue.6414 , pp. 739-742
    • Levine, B.1    Huang, Q.2    Isaacs, J.T.3    Reed, J.C.4    Griffin, D.E.5    Hardwick, J.M.6
  • 46
    • 1642553367 scopus 로고    scopus 로고
    • Alphaviruses and apoptosis
    • Li ML, Stollar V. Alphaviruses and apoptosis. Int Rev Immunol 2004; 23:7-24.
    • (2004) Int Rev Immunol , vol.23 , pp. 7-24
    • Li, M.L.1    Stollar, V.2
  • 47
    • 36849058164 scopus 로고    scopus 로고
    • Novel vectors expressing anti-apoptotic protein Bcl-2 to study cell death in Semliki Forest virus-infected cells
    • DOI 10.1016/j.virusres.2007.08.008, PII S016817020700305X
    • Kiiver K, Merits A, Sarand I. Novel vectors expressing anti-apoptotic protein Bcl-2 to study cell death in Semliki Forest virus-infected cells. Virus Res 2008; 131:54-64. (Pubitemid 350235681)
    • (2008) Virus Research , vol.131 , Issue.1 , pp. 54-64
    • Kiiver, K.1    Merits, A.2    Sarand, I.3
  • 48
    • 0030920239 scopus 로고    scopus 로고
    • The NS1 protein of the autonomous parvovirus minute virus of mice blocks cellular DNA replication: A consequence of lesions to the chromatin?
    • Op De Beeck A, Caillet-Fauquet P. The NS1 protein of the autonomous parvovirus minute virus of mice blocks cellular DNA replication: a consequence of lesions to the chromatin? J Virol 1997; 71:5323-5329
    • (1997) J Virol , vol.71 , pp. 5323-5329
    • De Op Beeck, A.1    Caillet-Fauquet, P.2
  • 49
    • 0034663781 scopus 로고    scopus 로고
    • Inhibition of S-phase progression by adenoassociated virus Rep78 protein is mediated by hypophosphorylated pRb
    • Saudan P, Vlach J, Beard P. Inhibition of S phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRb. EMBO J 2000; 19:4351-4361 (Pubitemid 30623746)
    • (2000) EMBO Journal , vol.19 , Issue.16 , pp. 4351-4361
    • Saudan, P.1    Vlach, J.2    Beard, P.3
  • 50
    • 34547808270 scopus 로고    scopus 로고
    • Cell cycle arrest and apoptosis induced by the coronavirus infectious bronchitis virus in the absence of p53
    • Li FQ, Tam JP, Liu DX. Cell cycle arrest and apoptosis induced by the coronavirus infectious bronchitis virus in the absence of p53. Virology 2007; 365:435-445
    • (2007) Virology , vol.365 , pp. 435-445
    • Li, F.Q.1    Tam, J.P.2    Liu, D.X.3
  • 51
    • 0037042177 scopus 로고    scopus 로고
    • Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): Association with cell senescence and tumour-promoting activities of stromal fibroblasts
    • Roninson IB. Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts. Cancer Lett 2002; 179:1-14.
    • (2002) Cancer Lett , vol.179 , pp. 1-14
    • Roninson, I.B.1
  • 53
    • 0032510026 scopus 로고    scopus 로고
    • Mutated p21(WAF1/CIP1/SDI1) lacking CDK-inhibitorg activity fails to prevent apoptosis in human colorectal carcinoma cells
    • Lu Y, Yamagishi N, Yagi T, Takebe H. Mutated p21(WAF1/CIP1/SDI1) lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells. Oncogene 1998; 16:705-712 (Pubitemid 28076081)
    • (1998) Oncogene , vol.16 , Issue.6 , pp. 705-712
    • Lu, Y.1    Yamagishi, N.2    Yagi, T.3    Takebe, H.4
  • 54
    • 0037086282 scopus 로고    scopus 로고
    • Selective sensitization of transformed cells to flavopiridol-induced apoptosis following recruitment to S phase
    • Matranga CB, Shapiro GI. Selective sensitization of transformed cells to flavopiridol-induced apoptosis following recruitment to S phase. Cancer Res 2002; 62:1707-1717
    • (2002) Cancer Res , vol.62 , pp. 1707-1717
    • Matranga, C.B.1    Shapiro, G.I.2
  • 61
    • 0034193778 scopus 로고    scopus 로고
    • The nucleolus: An old factory with unexpected capabilities
    • DOI 10.1016/S0962-8924(00)01738-4, PII S0962892400017384
    • Olson MO, Dundr M, Szebeni A. The nucleolus: an old factory with unexpected capabilities. Trends Cell Biol 2000; 10:189-196 (Pubitemid 30193267)
    • (2000) Trends in Cell Biology , vol.10 , Issue.5 , pp. 189-196
    • Olson, M.O.J.1    Dundr, M.2    Szebeni, A.3
  • 63
    • 0023852444 scopus 로고
    • Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores
    • DOI 10.1016/0092-8674(88)90403-5
    • Richardson WD, Mills AD, Dilworth SM, Laskey RA, Dingwall C. Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores. Cell 1988; 52:655-664 (Pubitemid 18078643)
    • (1988) Cell , vol.52 , Issue.5 , pp. 655-664
    • Richardson, W.D.1    Mills, A.D.2    Dilworth, S.M.3    Laskey, R.A.4    Dingwall, C.5
  • 64
    • 0032917157 scopus 로고    scopus 로고
    • Nucleolar protein B23 has molecular chaperone activities
    • Szebeni A, Olson MO. Nucleolar protein B23 has molecular chaperone activities. Protein Sci 1999; 8:905-912 (Pubitemid 29165421)
    • (1999) Protein Science , vol.8 , Issue.4 , pp. 905-912
    • Szebeni, A.1    Olson, M.O.J.2
  • 65
    • 0025880226 scopus 로고
    • Nucleolin promotes secondary structure in ribosomal RNA
    • Sipos K, Olson MO. Nucleolin promotes secondary structure in ribosomal RNA. Biochem Biophys Res Commun 1991; 177:673-678
    • (1991) Biochem Biophys Res Commun , vol.177 , pp. 673-678
    • Sipos, K.1    Olson, M.O.2
  • 66
    • 0024966024 scopus 로고
    • Major nucleolar proteins shuttle between nucleus and cytoplasm
    • Borer RA, Lehner CF, Eppenberger HM, Nigg EA. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell 1989; 56:379-390
    • (1989) Cell , vol.56 , pp. 379-390
    • Borer, R.A.1    Lehner, C.F.2    Eppenberger, H.M.3    Nigg, E.A.4
  • 68
    • 0024325692 scopus 로고
    • Functional similarity of HIV-I rev and HTLV-I rex proteins: Identification of a new nucleolar-targeting signal in rev protein
    • DOI 10.1016/0006-291X(89)90767-5
    • Kubota S, Siomi H, Satoh T, Endo S, Maki M, Hatanaka M. Functional similarity of HIV-I rev and HTLV-I rex proteins: identification of a new nucleolartargeting signal in rev protein. Biochem Biophys Res Commun 1989; 162:963-970 (Pubitemid 19214678)
    • (1989) Biochemical and Biophysical Research Communications , vol.162 , Issue.3 , pp. 963-970
    • Kubota, S.1    Siomi, H.2    Satoh, T.3    Endo, S.4    Maki, M.5    Hatanaka, M.6
  • 69
    • 0033000482 scopus 로고    scopus 로고
    • Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
    • DOI 10.1016/S1097-2765(00)80351-2
    • Zhang Y, Xiong Y. Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53. Mol Cell 1999; 3:579-591 (Pubitemid 29268441)
    • (1999) Molecular Cell , vol.3 , Issue.5 , pp. 579-591
    • Zhang, Y.1    Xiong, Y.2
  • 71
    • 0032488243 scopus 로고    scopus 로고
    • Intracellular trafficking and interactions of the HIV-1 Tat protein
    • DOI 10.1006/viro.1998.9400
    • Stauber RH, Pavlakis GN. Intracellular trafficking and interactions of the HIV-1 Tat protein. Virology 1998; 252:126-136 (Pubitemid 28564139)
    • (1998) Virology , vol.252 , Issue.1 , pp. 126-136
    • Stauber, R.H.1    Pavlakis, G.N.2
  • 72
    • 42449119438 scopus 로고    scopus 로고
    • Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus
    • Tamm K, Merits A, Sarand I. Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus. J Gen Virol 2008; 89:676-686
    • (2008) J Gen Virol , vol.89 , pp. 676-686
    • Tamm, K.1    Merits, A.2    Sarand, I.3
  • 73
    • 0028306659 scopus 로고
    • Nucleolar accumulation of Semliki Forest virus nucleocapsid C protein: Influence of metabolic status cytoskeleton and receptors
    • Jakob R. Nucleolar accumulation of Semliki Forest virus nucleocapsid C protein: influence of metabolic status, cytoskeleton and receptors. J Med Microbiol 1994; 40:389-392 (Pubitemid 24205151)
    • (1994) Journal of Medical Microbiology , vol.40 , Issue.6 , pp. 389-392
    • Jakob, R.1
  • 74
    • 0028112077 scopus 로고
    • Two nucleolar targeting signals present in the N-terminal part of Semliki Forest virus capsid protein
    • Favre D, Studer E, Michel MR. Two nucleolar targeting signals present in the N-terminal part of Semliki Forest virus capsid protein. Arch Virol 1994; 137:149-155 (Pubitemid 2115958)
    • (1994) Archives of Virology , vol.137 , Issue.1-2 , pp. 149-155
    • Favre, D.1    Studer, E.2    Michel, M.R.3
  • 75
    • 50249175241 scopus 로고    scopus 로고
    • Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?
    • Nolan L, Johnson PW, Ganesan A, Packham G, Crabb SJ. Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential? Br J Cancer 2008; 99:689-694
    • (2008) Br J Cancer , vol.99 , pp. 689-694
    • Nolan, L.1    Johnson, P.W.2    Ganesan, A.3    Packham, G.4    Crabb, S.J.5
  • 76
    • 33847780136 scopus 로고    scopus 로고
    • The multiple battles fought by anti-apoptotic p21
    • Janicke RU, Sohn D, Essmann F, Schulze-Osthoff K. The multiple battles fought by anti-apoptotic p21. Cell Cycle 2007; 6:407-413 (Pubitemid 46393442)
    • (2007) Cell Cycle , vol.6 , Issue.4 , pp. 407-413
    • Janicke, R.U.1    Sohn, D.2    Essmann, F.3    Schulze-Osthoff, K.4
  • 77
    • 0042197268 scopus 로고    scopus 로고
    • Are p27 and p21 cytoplasmic oncoproteins?
    • Blagosklonny MV. Are p27 and p21 cytoplasmic oncoproteins? Cell Cycle 2002; 1:391-393
    • (2002) Cell Cycle , vol.1 , pp. 391-393
    • Blagosklonny, M.V.1
  • 78
    • 0030902111 scopus 로고    scopus 로고
    • P21(Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells
    • Gorospe M, Cirielli C, Wang X, Seth P, Capogrossi MC, Holbrook NJ. p21(Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells. Oncogene 1997; 14:929-935 (Pubitemid 27122425)
    • (1997) Oncogene , vol.14 , Issue.8 , pp. 929-935
    • Gorospe, M.1    Cirielli, C.2    Wang, X.3    Seth, P.4    Capogrossi, M.C.5    Holbrook, N.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.