Lysozyme-lysozyme self-interactions as assessed by the osmotic second virial coefficient: Impact for physical protein stabilization

Biotechnology Journal

Volumn 4, Issue 9, 2009, Pages 1305-1319

  Le Brun, Virginie ^a   Friess, Wolfgang ^a   Schultz Fademrecht, Torsten ^b   Muehlau, Silke ^b   Garidel, Patrick ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

B22; Lysozyme; Osmotic second virial coefficient; Protein protein interaction; Self interaction chromatography; Stabilization

Indexed keywords

B22; LYSOZYME; OSMOTIC SECOND VIRIAL COEFFICIENT; PROTEIN-PROTEIN INTERACTION; SELF-INTERACTION CHROMATOGRAPHY;

CHROMATOGRAPHIC ANALYSIS; ENZYMES; EQUATIONS OF STATE; IONIC STRENGTH; OSMOSIS; SODIUM CHLORIDE; SOLUBILITY; STABILIZATION; TERNARY SYSTEMS;

CHROMATOGRAPHY;

GLYCEROL; LYSOZYME; MACROGOL; SODIUM CHLORIDE; SUCROSE;

AQUEOUS SOLUTION; ARTICLE; CHROMATOGRAPHY; IONIC STRENGTH; MOLECULAR WEIGHT; OSMOTIC SECOND VIRIAL COEFFICIENT; PARAMETERS OF MEASUREMENT AND ANALYSIS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTON TRANSPORT; SOLUBILITY; TEMPERATURE;

ALGORITHMS; BINDING SITES; COMPUTER SIMULATION; MODELS, CHEMICAL; MURAMIDASE; OSMOTIC PRESSURE; PROTEIN BINDING;

EID: 70350123028     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.200800274     Document Type: Article

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