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Volumn 182, Issue 2-3, 2009, Pages 148-158

Glucocorticoid and adrenalectomy effects on the rat aryl hydrocarbon receptor pathway depend on the dosing regimen and post-surgical time

Author keywords

3 Methylcholanthrene; Adrenalectomy; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor nuclear translocator; Cytochrome P450 1B1; Glucocorticoids

Indexed keywords

3 METHYLCHOLANTHRENE; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1B1; DEXAMETHASONE; HYPOXIA INDUCIBLE FACTOR 1BETA; MESSENGER RNA;

EID: 70350106541     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.07.005     Document Type: Article
Times cited : (8)

References (56)
  • 1
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • Denison M.S., and Nagy S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 43 (2003) 309-334
    • (2003) Annu. Rev. Pharmacol. Toxicol. , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 2
    • 30044452058 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries
    • Tijet N., Boutros P.C., Moffat I.D., Okey A.B., Tuomisto J., and Pohjanvirta R. Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol. Pharmacol. 69 (2006) 140-153
    • (2006) Mol. Pharmacol. , vol.69 , pp. 140-153
    • Tijet, N.1    Boutros, P.C.2    Moffat, I.D.3    Okey, A.B.4    Tuomisto, J.5    Pohjanvirta, R.6
  • 3
    • 0029118476 scopus 로고
    • Xenobiotic-inducible transcription of cytochrome P450 genes
    • Denison M.S., and Whitlock J.P. Xenobiotic-inducible transcription of cytochrome P450 genes. J. Biol. Chem. 270 (1995) 18175-18178
    • (1995) J. Biol. Chem. , vol.270 , pp. 18175-18178
    • Denison, M.S.1    Whitlock, J.P.2
  • 4
    • 0037450429 scopus 로고    scopus 로고
    • Functional role of AhR in the expression of toxic effects by TCDD
    • Mimura J., and Fujii-Kuriyama Y. Functional role of AhR in the expression of toxic effects by TCDD. Biochim. Biophys. Acta 1619 (2003) 263-268
    • (2003) Biochim. Biophys. Acta , vol.1619 , pp. 263-268
    • Mimura, J.1    Fujii-Kuriyama, Y.2
  • 5
    • 0028033592 scopus 로고
    • Tissue specific expression of the rat Ah-receptor and ARNT mRNAs
    • Carver L.A., Hogenesch J.B., and Bradfield C.A. Tissue specific expression of the rat Ah-receptor and ARNT mRNAs. Nucleic Acids Res. 22 (1994) 3038-3044
    • (1994) Nucleic Acids Res. , vol.22 , pp. 3038-3044
    • Carver, L.A.1    Hogenesch, J.B.2    Bradfield, C.A.3
  • 6
    • 0020010617 scopus 로고
    • 2, 3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity
    • Poland A., and Knutson J.C. 2, 3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22 (1982) 517-554
    • (1982) Annu. Rev. Pharmacol. Toxicol. , vol.22 , pp. 517-554
    • Poland, A.1    Knutson, J.C.2
  • 7
    • 0018139079 scopus 로고
    • Pituitary involvement in the sexual differentiation and 3-methylcholanthrene induction of rat liver microsomal monooxygenases
    • Burke M.D., Orrenius S., and Gustafsson J.-A. Pituitary involvement in the sexual differentiation and 3-methylcholanthrene induction of rat liver microsomal monooxygenases. Biochem. Pharmacol. 27 (1978) 1125-1128
    • (1978) Biochem. Pharmacol. , vol.27 , pp. 1125-1128
    • Burke, M.D.1    Orrenius, S.2    Gustafsson, J.-A.3
  • 8
    • 0036935229 scopus 로고    scopus 로고
    • Aromatic hydrocarbon receptor expression and function in liver of hypophysectomized male rats
    • Timsit Y.E., Chia F.S.-C., Bhathena A., and Riddick D.S. Aromatic hydrocarbon receptor expression and function in liver of hypophysectomized male rats. Toxicol. Appl. Pharmacol. 185 (2002) 136-145
    • (2002) Toxicol. Appl. Pharmacol. , vol.185 , pp. 136-145
    • Timsit, Y.E.1    Chia, F.S.-C.2    Bhathena, A.3    Riddick, D.S.4
  • 10
    • 0032970253 scopus 로고    scopus 로고
    • Role of canonical glucocorticoid responsive elements in modulating expression of genes regulated by the aryl hydrocarbon receptor
    • Linder M.W., Falkner K.C., Srinivasan G., Hines R.N., and Prough R.A. Role of canonical glucocorticoid responsive elements in modulating expression of genes regulated by the aryl hydrocarbon receptor. Drug Metab. Rev. 31 (1999) 247-271
    • (1999) Drug Metab. Rev. , vol.31 , pp. 247-271
    • Linder, M.W.1    Falkner, K.C.2    Srinivasan, G.3    Hines, R.N.4    Prough, R.A.5
  • 11
    • 1542686227 scopus 로고    scopus 로고
    • Modulation of AhR-mediated CYP1A1 mRNA and EROD activities by 17β-estradiol and dexamethasone in TCDD-induced H4IIE cells
    • Lai K.P., Wong M.H., and Wong C.K.C. Modulation of AhR-mediated CYP1A1 mRNA and EROD activities by 17β-estradiol and dexamethasone in TCDD-induced H4IIE cells. Toxicol. Sci. 78 (2004) 41-49
    • (2004) Toxicol. Sci. , vol.78 , pp. 41-49
    • Lai, K.P.1    Wong, M.H.2    Wong, C.K.C.3
  • 12
    • 0025029021 scopus 로고
    • Dexamethasone-mediated potentiation of P450IA1 induction in H4IIEC3/T hepatoma cells is dependent on a time-consuming process and associated with induction of the Ah receptor
    • Wiebel F.J., and Cikryt P. Dexamethasone-mediated potentiation of P450IA1 induction in H4IIEC3/T hepatoma cells is dependent on a time-consuming process and associated with induction of the Ah receptor. Chem. -Biol. Interact. 76 (1990) 307-320
    • (1990) Chem. -Biol. Interact. , vol.76 , pp. 307-320
    • Wiebel, F.J.1    Cikryt, P.2
  • 13
    • 0024332365 scopus 로고
    • Potentiation of 3-methylcholanthrene induction of rat hepatic cytochrome P450IA1 by dexamethesone in vivo
    • Sherratt A.J., Banet D.E., Linder M.W., and Prough R.A. Potentiation of 3-methylcholanthrene induction of rat hepatic cytochrome P450IA1 by dexamethesone in vivo. J. Pharmacol. Exp. Ther. 249 (1989) 667-672
    • (1989) J. Pharmacol. Exp. Ther. , vol.249 , pp. 667-672
    • Sherratt, A.J.1    Banet, D.E.2    Linder, M.W.3    Prough, R.A.4
  • 14
    • 0029859993 scopus 로고    scopus 로고
    • Cytochromes P450. 8. Hormonal regulation of hepatic enzymes involved in foreign compound metabolism
    • Prough R.A., Linder M.W., Pinaire J.A., Xiao G.H., and Falkner K.C. Cytochromes P450. 8. Hormonal regulation of hepatic enzymes involved in foreign compound metabolism. FASEB J. 10 (1996) 1369-1377
    • (1996) FASEB J. , vol.10 , pp. 1369-1377
    • Prough, R.A.1    Linder, M.W.2    Pinaire, J.A.3    Xiao, G.H.4    Falkner, K.C.5
  • 16
    • 11144262283 scopus 로고    scopus 로고
    • The effect of synthetic glucocorticoid, dexamethasone on CYP1A1 inducibility in adult rat and human hepatocytes
    • Monostory K., Kohalmy K., Prough R.A., Kobori L., and Vereczkey L. The effect of synthetic glucocorticoid, dexamethasone on CYP1A1 inducibility in adult rat and human hepatocytes. FEBS Lett. 579 (2005) 229-235
    • (2005) FEBS Lett. , vol.579 , pp. 229-235
    • Monostory, K.1    Kohalmy, K.2    Prough, R.A.3    Kobori, L.4    Vereczkey, L.5
  • 17
    • 62549089278 scopus 로고    scopus 로고
    • Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes
    • Vrzal R., Stejskalova L., Monostory K., Maurel P., Bachleda P., Pavek P., and Dvorak Z. Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes. Chem. -Biol. Interact. 179 (2009) 288-296
    • (2009) Chem. -Biol. Interact. , vol.179 , pp. 288-296
    • Vrzal, R.1    Stejskalova, L.2    Monostory, K.3    Maurel, P.4    Bachleda, P.5    Pavek, P.6    Dvorak, Z.7
  • 18
    • 67649985989 scopus 로고    scopus 로고
    • Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor
    • Wang S.-H., Liang C.-T., Liu Y.-W., Huang M.-C., Huang S.-C., Hong W.-F., and Su J.-G.J. Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor. Toxicology 262 (2009) 87-97
    • (2009) Toxicology , vol.262 , pp. 87-97
    • Wang, S.-H.1    Liang, C.-T.2    Liu, Y.-W.3    Huang, M.-C.4    Huang, S.-C.5    Hong, W.-F.6    Su, J.-G.J.7
  • 19
    • 38449091780 scopus 로고    scopus 로고
    • Glucocorticoid-enhanced expression of dioxin target genes through regulation of the rat aryl hydrocarbon receptor
    • Sonneveld E., Jonas A., Meijer O.C., Brouwer A., and van der Burg B. Glucocorticoid-enhanced expression of dioxin target genes through regulation of the rat aryl hydrocarbon receptor. Toxicol. Sci. 99 (2007) 455-469
    • (2007) Toxicol. Sci. , vol.99 , pp. 455-469
    • Sonneveld, E.1    Jonas, A.2    Meijer, O.C.3    Brouwer, A.4    van der Burg, B.5
  • 20
    • 0031785466 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulation of cytochrome P4501B1 in rat mammary fibroblasts: evidence for transcriptional repression by glucocorticoids
    • Brake P.B., Zhang L.Y., and Jefcoate C.R. Aryl hydrocarbon receptor regulation of cytochrome P4501B1 in rat mammary fibroblasts: evidence for transcriptional repression by glucocorticoids. Mol. Pharmacol. 54 (1998) 825-833
    • (1998) Mol. Pharmacol. , vol.54 , pp. 825-833
    • Brake, P.B.1    Zhang, L.Y.2    Jefcoate, C.R.3
  • 21
    • 40849108656 scopus 로고    scopus 로고
    • An evidence for regulatory cross-talk between aryl hydrocarbon receptor and glucocorticoid receptor in HepG2 cells
    • Dvorak Z., Vrzal R., Pavek P., and Ulrichova J. An evidence for regulatory cross-talk between aryl hydrocarbon receptor and glucocorticoid receptor in HepG2 cells. Physiol. Res. 57 (2008) 427-435
    • (2008) Physiol. Res. , vol.57 , pp. 427-435
    • Dvorak, Z.1    Vrzal, R.2    Pavek, P.3    Ulrichova, J.4
  • 22
    • 40849088078 scopus 로고    scopus 로고
    • Regulation of aryl hydrocarbon receptor expression and function by glucocorticoids in mouse hepatoma cells
    • Bielefeld K.A., Lee C., and Riddick D.S. Regulation of aryl hydrocarbon receptor expression and function by glucocorticoids in mouse hepatoma cells. Drug Metab. Dispos. 36 (2008) 543-551
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 543-551
    • Bielefeld, K.A.1    Lee, C.2    Riddick, D.S.3
  • 23
    • 0027937244 scopus 로고
    • Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone
    • Abbott B.D., Perdew G.H., Buckalew A.R., and Birnbaum L.S. Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone. Toxicol. Appl. Pharmacol. 128 (1994) 138-150
    • (1994) Toxicol. Appl. Pharmacol. , vol.128 , pp. 138-150
    • Abbott, B.D.1    Perdew, G.H.2    Buckalew, A.R.3    Birnbaum, L.S.4
  • 24
    • 0018569935 scopus 로고
    • Ontogeny of the rat hepatic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin and its endocrine independence
    • Carlstedt-Duke J.M., Elfstrom G., Hogberg B., and Gustafsson J.-A. Ontogeny of the rat hepatic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin and its endocrine independence. Cancer Res. 39 (1979) 4653-4656
    • (1979) Cancer Res. , vol.39 , pp. 4653-4656
    • Carlstedt-Duke, J.M.1    Elfstrom, G.2    Hogberg, B.3    Gustafsson, J.-A.4
  • 25
    • 0028207310 scopus 로고
    • The aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator protein show distinct subcellular localizations in Hepa-1c1c7 cells by immunofluorescence microscopy
    • Pollenz R.S., Sattler C.A., and Poland A. The aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator protein show distinct subcellular localizations in Hepa-1c1c7 cells by immunofluorescence microscopy. Mol. Pharmacol. 45 (1994) 428-438
    • (1994) Mol. Pharmacol. , vol.45 , pp. 428-438
    • Pollenz, R.S.1    Sattler, C.A.2    Poland, A.3
  • 26
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 27
    • 0020463374 scopus 로고
    • The examination and quantitation of tissue cytosolic receptors for 2,3,7,8-tetrachlorodibenzo-p-dioxin using hydroxylapatite
    • Gasiewicz T.A., and Neal R.A. The examination and quantitation of tissue cytosolic receptors for 2,3,7,8-tetrachlorodibenzo-p-dioxin using hydroxylapatite. Anal. Biochem. 124 (1982) 1-11
    • (1982) Anal. Biochem. , vol.124 , pp. 1-11
    • Gasiewicz, T.A.1    Neal, R.A.2
  • 28
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 29
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162 (1987) 156-159
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 30
    • 0035880885 scopus 로고    scopus 로고
    • Persistent, low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effect on aryl hydrocarbon receptor expression in a dioxin-resistance model
    • Franc M.A., Pohjanvirta R., Tuomisto J., and Okey A.B. Persistent, low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effect on aryl hydrocarbon receptor expression in a dioxin-resistance model. Toxicol. Appl. Pharmacol. 175 (2001) 43-53
    • (2001) Toxicol. Appl. Pharmacol. , vol.175 , pp. 43-53
    • Franc, M.A.1    Pohjanvirta, R.2    Tuomisto, J.3    Okey, A.B.4
  • 31
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • Rozen S., and Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol. 132 (2000) 365-386
    • (2000) Methods Mol. Biol. , vol.132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 32
    • 7244260513 scopus 로고    scopus 로고
    • PUNS: transcriptomic- and genomic-in silico PCR for enhanced primer design
    • Boutros P.C., and Okey A.B. PUNS: transcriptomic- and genomic-in silico PCR for enhanced primer design. Bioinformatics 20 (2004) 2399-2400
    • (2004) Bioinformatics , vol.20 , pp. 2399-2400
    • Boutros, P.C.1    Okey, A.B.2
  • 33
    • 0021928218 scopus 로고
    • A hydroxylapatite microassay for receptor binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene in various target tissues
    • Poellinger L., Lund J., Dahlberg E., and Gustafsson J.-A. A hydroxylapatite microassay for receptor binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene in various target tissues. Anal. Biochem. 144 (1985) 371-384
    • (1985) Anal. Biochem. , vol.144 , pp. 371-384
    • Poellinger, L.1    Lund, J.2    Dahlberg, E.3    Gustafsson, J.-A.4
  • 34
    • 0021987884 scopus 로고
    • Identification of the Ah receptor in selected mammalian species and induction of aryl hydrocarbon hydroxylase
    • Denison M.S., and Wilkinson C.F. Identification of the Ah receptor in selected mammalian species and induction of aryl hydrocarbon hydroxylase. Eur. J. Biochem. 147 (1985) 429-435
    • (1985) Eur. J. Biochem. , vol.147 , pp. 429-435
    • Denison, M.S.1    Wilkinson, C.F.2
  • 35
  • 36
    • 0032449041 scopus 로고    scopus 로고
    • Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver
    • Sun Y.N., DuBois D.C., Almon R.R., Pyszczynski N.A., and Jusko W.J. Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver. J. Pharmacokinet. Biopharm. 26 (1998) 619-648
    • (1998) J. Pharmacokinet. Biopharm. , vol.26 , pp. 619-648
    • Sun, Y.N.1    DuBois, D.C.2    Almon, R.R.3    Pyszczynski, N.A.4    Jusko, W.J.5
  • 37
    • 0014590169 scopus 로고
    • The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains and developmental and hormonal states
    • Nebert D.W., and Gelboin H.V. The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains and developmental and hormonal states. Arch. Biochem. Biophys. 134 (1969) 76-89
    • (1969) Arch. Biochem. Biophys. , vol.134 , pp. 76-89
    • Nebert, D.W.1    Gelboin, H.V.2
  • 39
    • 0041324898 scopus 로고    scopus 로고
    • The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: molecular mechanisms for gene repression
    • DeBosscher K., VandenBerghe W., and Haegeman G. The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: molecular mechanisms for gene repression. Endocrine Rev. 24 (2003) 488-522
    • (2003) Endocrine Rev. , vol.24 , pp. 488-522
    • DeBosscher, K.1    VandenBerghe, W.2    Haegeman, G.3
  • 40
    • 0026572821 scopus 로고
    • Effect of adrenalectomy and high-fat diet on the fatty Zucker rat
    • Bray G.A., Stern J.S., and Castonguay T.W. Effect of adrenalectomy and high-fat diet on the fatty Zucker rat. Am. J. Physiol. 262 (1992) E32-39
    • (1992) Am. J. Physiol. , vol.262
    • Bray, G.A.1    Stern, J.S.2    Castonguay, T.W.3
  • 41
    • 0031877720 scopus 로고    scopus 로고
    • Effects of adrenalectomy and glucocorticoid receptor antagonist, RU38486, on pituitary growth hormone-releasing hormone receptor gene expression in rats
    • Ohyama T., Sato M., Ohye H., Murao K., Niimi M., and Takahara J. Effects of adrenalectomy and glucocorticoid receptor antagonist, RU38486, on pituitary growth hormone-releasing hormone receptor gene expression in rats. Peptides 19 (1998) 1063-1067
    • (1998) Peptides , vol.19 , pp. 1063-1067
    • Ohyama, T.1    Sato, M.2    Ohye, H.3    Murao, K.4    Niimi, M.5    Takahara, J.6
  • 42
    • 0037145007 scopus 로고    scopus 로고
    • The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation
    • Pollenz R.S. The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation. Chem. -Biol. Interact. 141 (2002) 41-61
    • (2002) Chem. -Biol. Interact. , vol.141 , pp. 41-61
    • Pollenz, R.S.1
  • 43
    • 0031543526 scopus 로고    scopus 로고
    • The Ah receptor is a sensitive target of geldanamycin-induced protein turnover
    • Chen H.S., Singh S.S., and Perdew G.H. The Ah receptor is a sensitive target of geldanamycin-induced protein turnover. Arch. Biochem. Biophys. 348 (1997) 190-198
    • (1997) Arch. Biochem. Biophys. , vol.348 , pp. 190-198
    • Chen, H.S.1    Singh, S.S.2    Perdew, G.H.3
  • 44
    • 0031944704 scopus 로고    scopus 로고
    • Female Sprague-Dawley rats exposed to a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibit sustained depletion of aryl hydrocarbon receptor protein in liver, spleen, thymus, and lung
    • Pollenz R.S., Santostefano M.J., Klett E., Richardson V.M., Necela B., and Birnbaum L.S. Female Sprague-Dawley rats exposed to a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibit sustained depletion of aryl hydrocarbon receptor protein in liver, spleen, thymus, and lung. Toxicol. Sci. 42 (1998) 117-128
    • (1998) Toxicol. Sci. , vol.42 , pp. 117-128
    • Pollenz, R.S.1    Santostefano, M.J.2    Klett, E.3    Richardson, V.M.4    Necela, B.5    Birnbaum, L.S.6
  • 45
    • 0035894283 scopus 로고    scopus 로고
    • In vivo up-regulation of aryl hydrocarbon receptor expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in a dioxin-resistant rat model
    • Franc M.A., Pohjanvirta R., Tuomisto J., and Okey A.B. In vivo up-regulation of aryl hydrocarbon receptor expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in a dioxin-resistant rat model. Biochem. Pharmacol. 62 (2001) 1565-1578
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 1565-1578
    • Franc, M.A.1    Pohjanvirta, R.2    Tuomisto, J.3    Okey, A.B.4
  • 46
    • 19944406443 scopus 로고    scopus 로고
    • CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3',4,4',5-pentachlorobiphenyl
    • Wakui S., Yokoo K., Takahashi H., Muto T., Suzuki Y., Kanai Y., Hano H., Furusato M., and Endou H. CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3',4,4',5-pentachlorobiphenyl. Toxicology 211 (2005) 231-241
    • (2005) Toxicology , vol.211 , pp. 231-241
    • Wakui, S.1    Yokoo, K.2    Takahashi, H.3    Muto, T.4    Suzuki, Y.5    Kanai, Y.6    Hano, H.7    Furusato, M.8    Endou, H.9
  • 47
    • 0031453404 scopus 로고    scopus 로고
    • Leukocyte activation induces aryl hydrocarbon receptor up-regulation, DNA binding, and increased CYP1A1 expression in the absence of exogenous ligand
    • Crawford R.B., Holsapple M.P., and Kaminski N.E. Leukocyte activation induces aryl hydrocarbon receptor up-regulation, DNA binding, and increased CYP1A1 expression in the absence of exogenous ligand. Mol. Pharmacol. 52 (1997) 921-927
    • (1997) Mol. Pharmacol. , vol.52 , pp. 921-927
    • Crawford, R.B.1    Holsapple, M.P.2    Kaminski, N.E.3
  • 48
    • 27144451563 scopus 로고    scopus 로고
    • Pharmacogenomic responses of rat liver to methylprednisolone: an approach to mining a rich microarray time series
    • Almon R.R., Dubois D.C., Jin J.Y., and Jusko W.J. Pharmacogenomic responses of rat liver to methylprednisolone: an approach to mining a rich microarray time series. AAPS J. 7 (2005) E156-194
    • (2005) AAPS J. , vol.7
    • Almon, R.R.1    Dubois, D.C.2    Jin, J.Y.3    Jusko, W.J.4
  • 49
    • 0030943461 scopus 로고    scopus 로고
    • Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT
    • Maltepe E., Schmidt J.V., Baunoch D., Bradfield C.A., and Simon M.C. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 386 (1997) 403-407
    • (1997) Nature , vol.386 , pp. 403-407
    • Maltepe, E.1    Schmidt, J.V.2    Baunoch, D.3    Bradfield, C.A.4    Simon, M.C.5
  • 50
    • 33745656989 scopus 로고    scopus 로고
    • Regulating the regulator: factors that control levels and activity of the aryl hydrocarbon receptor
    • Harper P.A., Riddick D.S., and Okey A.B. Regulating the regulator: factors that control levels and activity of the aryl hydrocarbon receptor. Biochem. Pharmacol. 72 (2006) 267-279
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 267-279
    • Harper, P.A.1    Riddick, D.S.2    Okey, A.B.3
  • 51
    • 0032589068 scopus 로고    scopus 로고
    • RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone
    • Abbott B.D., Schmid J.E., Brown J.G., Wood C.R., White R.D., Buckalew A.R., and Held G.A. RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone. Toxicol. Sci. 47 (1999) 76-85
    • (1999) Toxicol. Sci. , vol.47 , pp. 76-85
    • Abbott, B.D.1    Schmid, J.E.2    Brown, J.G.3    Wood, C.R.4    White, R.D.5    Buckalew, A.R.6    Held, G.A.7
  • 54
    • 37349014576 scopus 로고    scopus 로고
    • Microarray analysis of hepatic gene expression in pyrazole-mediated hepatotoxicity: identification of potential stimuli of Cyp2a5 induction
    • Nichols K.D., and Kirby G.M. Microarray analysis of hepatic gene expression in pyrazole-mediated hepatotoxicity: identification of potential stimuli of Cyp2a5 induction. Biochem. Pharmacol. 75 (2008) 538-551
    • (2008) Biochem. Pharmacol. , vol.75 , pp. 538-551
    • Nichols, K.D.1    Kirby, G.M.2


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