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Volumn 42, Issue 2, 1998, Pages 117-128

Female Sprague-Dawley rats exposed to a single oral dose of 2,3,7,8- tetrachlorodibenzo-p-dioxin exhibit sustained depletion of aryl hydrocarbon receptor protein in liver, spleen, thymus, and lung

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; PROTEIN;

EID: 0031944704     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1006/toxs.1998.2439     Document Type: Article
Times cited : (74)

References (40)
  • 1
    • 0028244858 scopus 로고
    • Ah receptor in mouse embryonic palate and the effects of TCDD on receptor expression
    • Abbott, B. D., Perdew, G. H., and Birnbaum, L. S. (1994). Ah receptor in mouse embryonic palate and the effects of TCDD on receptor expression. Toxicol. Applied Pharm. 126, 16-25.
    • (1994) Toxicol. Applied Pharm. , vol.126 , pp. 16-25
    • Abbott, B.D.1    Perdew, G.H.2    Birnbaum, L.S.3
  • 2
    • 0028998310 scopus 로고
    • Constitutive function of the basic-helix-loop-helix/PAS factor ARNT: Regulation of target promoters via the E-box motif
    • Antonsson, C., Arulampalam, V., Whitelaw, M. A., Petersson, S., and Poellinger, L. (1995). Constitutive function of the basic-helix-loop-helix/PAS factor ARNT: Regulation of target promoters via the E-box motif. J. Biol. Chem. 270, 13968-13972.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13968-13972
    • Antonsson, C.1    Arulampalam, V.2    Whitelaw, M.A.3    Petersson, S.4    Poellinger, L.5
  • 3
    • 0023637761 scopus 로고
    • Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: Effects on enzyme activity and immunotoxicity
    • Bannister, R., Davis, D., Zacharewski, T., Tizard, I., and Safe, S. (1987). Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: Effects on enzyme activity and immunotoxicity. Toxicology 46, 29-42.
    • (1987) Toxicology , vol.46 , pp. 29-42
    • Bannister, R.1    Davis, D.2    Zacharewski, T.3    Tizard, I.4    Safe, S.5
  • 4
    • 0028596186 scopus 로고
    • The mechanism of dioxin toxicity: Relationship to risk assessment
    • Birnbaum, L. S. (1994a). The mechanism of dioxin toxicity: Relationship to risk assessment. Environ. Health. Perspect. 102 (Suppl. 9), 157-167.
    • (1994) Environ. Health. Perspect. , vol.102 , Issue.9 SUPPL. , pp. 157-167
    • Birnbaum, L.S.1
  • 5
    • 0028188487 scopus 로고
    • Evidence for the role of the Ah receptor in response to dioxin
    • (H. L. Spitzer, T. J. Slaga, W. F. Greenlee, and M. McClain, Eds.), Wiley-Liss, New York
    • Birnbaum, L. S. (1994b). Evidence for the role of the Ah receptor in response to dioxin. In Receptor-Mediated Biological Processes: Implications for Evaluating Carcinogenesis (H. L. Spitzer, T. J. Slaga, W. F. Greenlee, and M. McClain, Eds.), pp. 139-154. Wiley-Liss, New York.
    • (1994) Receptor-Mediated Biological Processes: Implications for Evaluating Carcinogenesis , pp. 139-154
    • Birnbaum, L.S.1
  • 6
    • 0025942673 scopus 로고
    • Disposition of 2,3,7,8-tetrabromodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat: Biliary excretion and induction of cytochromes CYP1A1 and CYP1A2
    • Buckley-Kedderis, L., Diliberto, J. J., Linko, P., Goldstein, J. A., and Birnbaum, L. S. (1991). Disposition of 2,3,7,8-tetrabromodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat: Biliary excretion and induction of cytochromes CYP1A1 and CYP1A2. Toxicol. Appl. Pharmacol. 111, 163-172.
    • (1991) Toxicol. Appl. Pharmacol. , vol.111 , pp. 163-172
    • Buckley-Kedderis, L.1    Diliberto, J.J.2    Linko, P.3    Goldstein, J.A.4    Birnbaum, L.S.5
  • 7
    • 0026725943 scopus 로고
    • Cloning of the Ah-receptor cDNA reveals a distinctive ligand activated transcription factor
    • Burbach, K. M., Poland, A., and Bradfield, C. A. (1992). Cloning of the Ah-receptor cDNA reveals a distinctive ligand activated transcription factor. Proc. Natl. Acad. Sci. USA 89, 8185-8189.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8185-8189
    • Burbach, K.M.1    Poland, A.2    Bradfield, C.A.3
  • 8
    • 0028033592 scopus 로고
    • Tissue specific expression of the rat Ah-receptor and ARNT mRNAs
    • Carver, L. A., Hogenesch, J. B., and Bradfield, C. A. (1994). Tissue specific expression of the rat Ah-receptor and ARNT mRNAs. Nucleic Acids Res. 22, 3038-3044.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 3038-3044
    • Carver, L.A.1    Hogenesch, J.B.2    Bradfield, C.A.3
  • 9
    • 0022501185 scopus 로고
    • Elevation of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) polychlorinated biphenyls
    • Denomme, M. A., Leece, B., Li, A., Towner, R., and Safe, S. (1986). Elevation of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) polychlorinated biphenyls. Biochem. Pharmacol. 35, 277-282.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 277-282
    • Denomme, M.A.1    Leece, B.2    Li, A.3    Towner, R.4    Safe, S.5
  • 10
    • 0028968614 scopus 로고
    • Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice
    • Diliberto, J. J., Akubue, P. I., Luebke, R. W., and Birnbaum, L. S. (1995). Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice. Toxicol. Appl. Pharmacol. 130, 197-208.
    • (1995) Toxicol. Appl. Pharmacol. , vol.130 , pp. 197-208
    • Diliberto, J.J.1    Akubue, P.I.2    Luebke, R.W.3    Birnbaum, L.S.4
  • 11
    • 0030583277 scopus 로고    scopus 로고
    • Cloning and selective expression in brain and kidney of ARNT2 homolous to the Ah receptor nuclear translocator (ARNT)
    • Drutel, G., Kathmann, M., Heron, A., Schwartz, J-C., and Arran, J-M. (1996). Cloning and selective expression in brain and kidney of ARNT2 homolous to the Ah receptor nuclear translocator (ARNT). Biochem. Biophys. Res. Commun. 225, 333-339.
    • (1996) Biochem. Biophys. Res. Commun. , vol.225 , pp. 333-339
    • Drutel, G.1    Kathmann, M.2    Heron, A.3    Schwartz, J.-C.4    Arran, J.-M.5
  • 13
    • 26844566935 scopus 로고    scopus 로고
    • Species-specific recombinant cell lines as a bioassay system for the detection of TCDD-like chemicals
    • Garrison. P. M., Tullis, K., Aarts, J. M. M. I. G., Brouwer, A., Geisy, J. P., and Denison, M. S. (1996). Species-specific recombinant cell lines as a bioassay system for the detection of TCDD-like chemicals. Fundam. Appl. Toxicol. 30, 194-203.
    • (1996) Fundam. Appl. Toxicol. , vol.30 , pp. 194-203
    • Garrison, P.M.1    Tullis, K.2    Aarts, J.M.M.I.G.3    Brouwer, A.4    Geisy, J.P.5    Denison, M.S.6
  • 14
    • 0021200784 scopus 로고
    • Cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Gasiewicz, T. A., and Rucci, G. (1984). Cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol. Phamacol. 26, 90-98.
    • (1984) Mol. Phamacol. , vol.26 , pp. 90-98
    • Gasiewicz, T.A.1    Rucci, G.2
  • 15
    • 0028944093 scopus 로고
    • Charcaterization of polyclonal antibodies to the aromatic hydrocarbon receptor
    • Giannone, J. V., Okey, A. B., and Harper, P. A. (1995). Charcaterization of polyclonal antibodies to the aromatic hydrocarbon receptor. Can. J. Physiol. Pharmacol. 73, 7-17.
    • (1995) Can. J. Physiol. Pharmacol. , vol.73 , pp. 7-17
    • Giannone, J.V.1    Okey, A.B.2    Harper, P.A.3
  • 16
    • 0029789568 scopus 로고    scopus 로고
    • Functional interference between hypoxia and dioxin signal transduction pathways: Competition for recruitment of the Amt transcription factor
    • Gradin, K., McGuire, J., Wenger, R. H., Kvietikova, I., Whitelaw, M. L., Toftgard, R., Tora, L., Gassmann, M., and Poellinger, L. (1996). Functional interference between hypoxia and dioxin signal transduction pathways: Competition for recruitment of the Amt transcription factor. Mol. Cell. Biol. 16, 5221-5321.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5221-5321
    • Gradin, K.1    McGuire, J.2    Wenger, R.H.3    Kvietikova, I.4    Whitelaw, M.L.5    Toftgard, R.6    Tora, L.7    Gassmann, M.8    Poellinger, L.9
  • 17
    • 0028987872 scopus 로고
    • The Aryl hydrocarbon receptor complex
    • Hankinson, O. (1995). The Aryl hydrocarbon receptor complex. Annu. Rev. Pharm. Tox. 35, 307-340.
    • (1995) Annu. Rev. Pharm. Tox. , vol.35 , pp. 307-340
    • Hankinson, O.1
  • 18
    • 0029928689 scopus 로고    scopus 로고
    • cDNA cloning and tissue specific expression of a novel bHLH/PAS factor (ARNT2) with close sequence similarity to the aryl hydrocarbon nuclear translocator (ARNT)
    • Hirose, K., Morita, M., Ema, M., Mimura, J., Hamada, H., Fuji, H., Saijo, Y., , Gotoh, O., Sogawa, K., and Fuji-Kuriyama, Y. (1996). cDNA cloning and tissue specific expression of a novel bHLH/PAS factor (ARNT2) with close sequence similarity to the aryl hydrocarbon nuclear translocator (ARNT). Mol. Cell. Biol. 16, 1706-1713.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1706-1713
    • Hirose, K.1    Morita, M.2    Ema, M.3    Mimura, J.4    Hamada, H.5    Fuji, H.6    Saijo, Y.7    Gotoh, O.8    Sogawa, K.9    Fuji-Kuriyama, Y.10
  • 19
    • 0030887045 scopus 로고    scopus 로고
    • Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway
    • Hogenesch, J. B., Chan, W. K., Jackiw, V. H., Brown, R. C., Gu, Y-Z., Pray-Grant, M., Perdew, G. H., and Bradfield, C. A. (1996). Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. J. Biol. Chem. 272, 8581-8593.
    • (1996) J. Biol. Chem. , vol.272 , pp. 8581-8593
    • Hogenesch, J.B.1    Chan, W.K.2    Jackiw, V.H.3    Brown, R.C.4    Gu, Y.-Z.5    Pray-Grant, M.6    Perdew, G.H.7    Bradfield, C.A.8
  • 20
    • 0030751810 scopus 로고    scopus 로고
    • Determination of aryl hydrocarbon receptor nuclear translocator protein concentration and subcellular localization in hepatic and nonhepatic cell culture lines
    • Holmes, J., and Pollenz, R. S. (1997). Determination of aryl hydrocarbon receptor nuclear translocator protein concentration and subcellular localization in hepatic and nonhepatic cell culture lines. Mol. Pharmacol. 52, 202-212.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 202-212
    • Holmes, J.1    Pollenz, R.S.2
  • 21
    • 0029788974 scopus 로고    scopus 로고
    • Induction of phosphoglycerate kinase 1 gene expression by hypoxia
    • Li, H., Ko, H. P., and Whitlock J. P., Jr. (1996). Induction of phosphoglycerate kinase 1 gene expression by hypoxia. J. Biol. Chem. 271, 21262-21267.
    • (1996) J. Biol. Chem. , vol.271 , pp. 21262-21267
    • Li, H.1    Ko, H.P.2    Whitlock Jr., J.P.3
  • 22
    • 0029963257 scopus 로고    scopus 로고
    • The AHR modulates the Hepa-1c1c7 cell cycle and differentiated state independently of dioxin
    • Ma, Q., and Whitlock, J. P., Jr. (1996). The AHR modulates the Hepa-1c1c7 cell cycle and differentiated state independently of dioxin Mol. Cell. Biol. 16, 2144-2150.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2144-2150
    • Ma, Q.1    Whitlock Jr., J.P.2
  • 23
    • 0030943461 scopus 로고    scopus 로고
    • Abnormal angiogenesis and response to glucose and oxygen deprivation in mice lacking the protein ARNT
    • Maltepe, E., Schmidt, J. V., Baunoch, D., Bradfield, C. A., and Simon, M. C. (1997). Abnormal angiogenesis and response to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 386, 403-406.
    • (1997) Nature , vol.386 , pp. 403-406
    • Maltepe, E.1    Schmidt, J.V.2    Baunoch, D.3    Bradfield, C.A.4    Simon, M.C.5
  • 24
    • 0021247878 scopus 로고
    • Binding of benzo(a)pyrene and dibenz(a,h)anthracene to the Ah receptor in mouse and rat hepatic cytosols
    • Okey, A. B., Dube, A. W., and Vella, L. M. (1984). Binding of benzo(a)pyrene and dibenz(a,h)anthracene to the Ah receptor in mouse and rat hepatic cytosols. Cancer Res. 44, 1426-1432.
    • (1984) Cancer Res. , vol.44 , pp. 1426-1432
    • Okey, A.B.1    Dube, A.W.2    Vella, L.M.3
  • 25
    • 0020010617 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related aromatic hydrocarbons: Examination of the mechanism of toxicity
    • Poland, A., and Knutson, J. C. (1982). 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related aromatic hydrocarbons: Examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22, 517-554.
    • (1982) Annu. Rev. Pharmacol. Toxicol. , vol.22 , pp. 517-554
    • Poland, A.1    Knutson, J.C.2
  • 26
    • 0028207310 scopus 로고
    • The aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator protein show distinct subcellular localization in Hepa 1c1c7 cell by immunofluorescence microscopy
    • Pollenz, R. S., Sattler, C. A., and Poland, A. (1994). The aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator protein show distinct subcellular localization in Hepa 1c1c7 cell by immunofluorescence microscopy. Mol. Pharmacol. 45, 428-438.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 428-438
    • Pollenz, R.S.1    Sattler, C.A.2    Poland, A.3
  • 27
    • 0029986534 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor but not the aryl hydrocarbon receptor nuclear translocator protein is rapidly depleted in hepatic and nonhepatic culture cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Pollenz, R. S. (1996a). The aryl hydrocarbon receptor but not the aryl hydrocarbon receptor nuclear translocator protein is rapidly depleted in hepatic and nonhepatic culture cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol. Pharmacol. 49, 391-398.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 391-398
    • Pollenz, R.S.1
  • 28
    • 0002370389 scopus 로고    scopus 로고
    • Linearity of western blotting with ECL: Quantification of changes in protein concentration in whole cell lysates
    • (P. Riis, Ed.), No. 9, Amersham, Arlington Heights. IL
    • Pollenz, R. S. (1996b). Linearity of western blotting with ECL: Quantification of changes in protein concentration in whole cell lysates. In ECL Highlights (P. Riis, Ed.), No. 9, pp. 2-3. Amersham, Arlington Heights. IL.
    • (1996) ECL Highlights , pp. 2-3
    • Pollenz, R.S.1
  • 29
    • 0029852242 scopus 로고    scopus 로고
    • Isolation and characterization of cDNAs from rainbow trout (Oncorhynchus mykiss) that encode two novel basic-helix-loop- Helix/PAS proteins with distinct functions in the presence of the aryl hydrocarbon receptor
    • Pollenz, R. S., Sullivan, H. L., Holmes, J., Necela, B., and Peterson, R. E. (1996). Isolation and characterization of cDNAs from rainbow trout (Oncorhynchus mykiss) that encode two novel basic-helix-loop-helix/PAS proteins with distinct functions in the presence of the aryl hydrocarbon receptor. J. Biol. Chem. 271, 30886-30896.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30886-30896
    • Pollenz, R.S.1    Sullivan, H.L.2    Holmes, J.3    Necela, B.4    Peterson, R.E.5
  • 30
    • 0026625037 scopus 로고
    • Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA Binding form of the Ah receptor
    • Reyes, H., Reisz-Porszasz, S., and Hankinson, O. (1992). Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA Binding form of the Ah receptor. Science 256, 1193-1195.
    • (1992) Science , vol.256 , pp. 1193-1195
    • Reyes, H.1    Reisz-Porszasz, S.2    Hankinson, O.3
  • 31
    • 0010417886 scopus 로고    scopus 로고
    • Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and ARNT expression, CYP1A1 induction, and Ah receptor downregulation
    • Roman, B. L., Pollenz, R. S., and Peterson, R. E. (1998). Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and ARNT expression, CYP1A1 induction, and Ah receptor downregulation. Toxicol. Appl. Phramacol. 150.
    • (1998) Toxicol. Appl. Phramacol. , vol.150
    • Roman, B.L.1    Pollenz, R.S.2    Peterson, R.E.3
  • 32
    • 0022555425 scopus 로고
    • Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans
    • Safe, S. H. (1986). Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans. Annu. Rev. Pharmacol. Toxocol. 26, 371-399.
    • (1986) Annu. Rev. Pharmacol. Toxocol. , vol.26 , pp. 371-399
    • Safe, S.H.1
  • 33
    • 26844560562 scopus 로고    scopus 로고
    • Subcellular localization of TCDD differs between the liver, lungs and kidneys after acute and subchronic exposure: Species/dose comparisons and possible mechanism
    • Santostefano, M. J., Johnson, K. L., Whisnant, N. A., Richardson, V. M., DeVito, M., Diliberto, J. J., and Birnbaum, L. S. (1996). Subcellular localization of TCDD differs between the liver, lungs and kidneys after acute and subchronic exposure: Species/dose comparisons and possible mechanism. Fundam. Appl. Toxicol. 34, 265-275.
    • (1996) Fundam. Appl. Toxicol. , vol.34 , pp. 265-275
    • Santostefano, M.J.1    Johnson, K.L.2    Whisnant, N.A.3    Richardson, V.M.4    DeVito, M.5    Diliberto, J.J.6    Birnbaum, L.S.7
  • 34
    • 0031557681 scopus 로고    scopus 로고
    • Differential time course and dose-response relationships of TCDD induced CYP1B1, CYP1A1 and CYP1A2 protein is rats
    • Santostefano, M. J., Ross, D. G., Savas, U., Jefcoate, C. R., and Birnbaum, L. S. (1997). Differential time course and dose-response relationships of TCDD induced CYP1B1, CYP1A1 and CYP1A2 protein is rats. Biochem. Biophys. Res. Commun. 233, 20-24.
    • (1997) Biochem. Biophys. Res. Commun. , vol.233 , pp. 20-24
    • Santostefano, M.J.1    Ross, D.G.2    Savas, U.3    Jefcoate, C.R.4    Birnbaum, L.S.5
  • 35
    • 0023236552 scopus 로고
    • Dose-dependent elevation of Ah receptor binding by TCDD in rat liver
    • Sloop, T. C., and Lucier, G. W. (1987). Dose-dependent elevation of Ah receptor binding by TCDD in rat liver. Toxicol. Appl. Pharmacol. 88, 329-337.
    • (1987) Toxicol. Appl. Pharmacol. , vol.88 , pp. 329-337
    • Sloop, T.C.1    Lucier, G.W.2
  • 37
    • 0027264543 scopus 로고
    • Half-life of the Aryl hydrocrbon receptor in Hepa-1 cells
    • Swanson, H. I., and Perdew, G. H. (1993). Half-life of the Aryl hydrocrbon receptor in Hepa-1 cells. Arch. Biochem. Biophys. 302, 167-174.
    • (1993) Arch. Biochem. Biophys. , vol.302 , pp. 167-174
    • Swanson, H.I.1    Perdew, G.H.2
  • 38
    • 0028865103 scopus 로고    scopus 로고
    • DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins
    • Swanson, H. I., Chan, W. K., and Bradfield, C. A. (1996). DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins. J. Biol. Chem. 270, 26292-26302.
    • (1996) J. Biol. Chem. , vol.270 , pp. 26292-26302
    • Swanson, H.I.1    Chan, W.K.2    Bradfield, C.A.3
  • 40
    • 0029888061 scopus 로고    scopus 로고
    • The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression
    • Wood, S. W., Gleadle, J. M., Pugh, C. W., Hankinson, O., and Ratcliffe, P. J. (1996). The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. J. Biol. Chem. 271, 15117-15123.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15117-15123
    • Wood, S.W.1    Gleadle, J.M.2    Pugh, C.W.3    Hankinson, O.4    Ratcliffe, P.J.5


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