7H-Dibenzo[c,g]carbazole and 5,9-dimethyldibenzo[c,g]carbazole exert multiple toxic events contributing to tumor promotion in rat liver epithelial 'stem-like' cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 596, Issue 1-2 SPEC. ISS., 2006, Pages 43-56

  Vondráček, Jan ^a,b   Švihálková Šindlerová, Lenka ^a   Pěnčíková, Kateřina ^b   Krčmář, Pavel ^b   Andrysík, Zdeněk ^a,b   Chramostová, Kateřina ^a   Marvanová, Soňa ^b   Valovičová, Zuzana ^c   Kozubík, Alois ^a   Gábelová, Alena ^c   Machala, Miroslav ^b  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

^b VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^c CANCER RESEARCH INSTITUTE   (Slovakia)

Author keywords

AhR activation; Apoptosis; Cell proliferation; Cytochromes P450; Dibenzocarbazoles; Gap junctional intercellular communication (GJIC)

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CARBAZOLE DERIVATIVE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; PROTEIN P53; SERINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL COMMUNICATION; CELL CYCLE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EPITHELIUM CELL; GAP JUNCTION; LIVER CARCINOGENESIS; LIVER CELL; METABOLISM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; STEM CELL; TISSUE SPECIFICITY; TOXICITY; TUMOR PROMOTION; UPREGULATION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BASE SEQUENCE; CARBAZOLES; CARCINOGENS; CELL DEATH; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; DNA PRIMERS; EPITHELIAL CELLS; LIVER; METHYLATION; MOLECULAR STRUCTURE; MUTAGENS; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 33645966830     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2005.11.005     Document Type: Article

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