Microarray analysis of hepatic gene expression in pyrazole-mediated hepatotoxicity: Identification of potential stimuli of Cyp2a5 induction

Biochemical Pharmacology

Volumn 75, Issue 2, 2008, Pages 538-551

  Nichols, Kathleen D ^a   Kirby, Gordon M ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

CYP2A5; Gene expression; Hepatotoxicity; Microarray; Pyrazole; Regulation

Indexed keywords

AMINO ACID; BILIRUBIN; CARBOHYDRATE; CYTOCHROME P450 2A5; GLUCOSE; GLYCOGEN; LIPID; MESSENGER RNA; PYRAZOLE; RNA; UREA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CARBOHYDRATE METABOLISM; CELL STRESS; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE EXPRESSION; GENETIC IDENTIFICATION; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; LIPID METABOLISM; LIVER TOXICITY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEPLETION; RNA SPLICING; UPREGULATION; UREA CYCLE;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BILIRUBIN; ENDOPLASMIC RETICULUM; ENZYME INDUCTION; GENE EXPRESSION REGULATION; GLUCOSE; HOMEOSTASIS; LIVER; MICE; MICE, INBRED C57BL; MIXED FUNCTION OXYGENASES; NITROGEN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PYRAZOLES; UREA;

EID: 37349014576     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.09.009     Document Type: Article

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