Increased cytokine productionin interleukin-18 receptor α-deficient cells is associated with dysregulation of suppressors of cytokine signaling

Journal of Biological Chemistry

Volumn 284, Issue 38, 2009, Pages 25900-25911

  Nold Petry, Claudia A ^a   Nold, Marcel F ^a   Nielsen, Jason W ^a   Bustamante, Alex ^a   Zepp, Jarod A ^a   Storm, Kathleen A ^b   Hong, Jae Woo ^c   Kim, Soo Hyun ^a,c   Dinarello, Charles A ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Source Molecular Diagnostics Inc   (United States)

^c Konkuk University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

A549 CELLS; ANTI-INFLAMMATORY RESPONSE; CHEMOKINES; CYTOKINES; HAIRPIN RNA; HUMAN BLOOD CELLS; IN-CELL; INTERLEUKIN-18; KNOCK OUTS; LIGAND BINDING; LIPOPOLYSACCHARIDES; MOUSE EMBRYONIC FIBROBLASTS; NEGATIVE FEEDBACK; PROINFLAMMATORY CYTOKINES; PROSTAGLANDINE; PROTEIN KINASE; SMALL INTERFERING RNA; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSORS OF CYTOKINE SIGNALING; WILD TYPES;

BLOOD; CELL CULTURE; FEEDBACK; INTERFERONS; LIGANDS; NUCLEIC ACIDS; PLASMA WAVES; POLYSACCHARIDES; RNA; SIGNALING;

CELL MEMBRANES;

INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 18 RECEPTOR ALPHA; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 14; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; STAT1 PROTEIN; CYTOKINE; IL18R1 PROTEIN, HUMAN; IL18R1 PROTEIN, MOUSE; PROTEIN KINASE; SOCS1 PROTEIN, HUMAN; SOCS1 PROTEIN, MOUSE; SOCS3 PROTEIN, HUMAN; SOCS3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO CELL; FIBROBLAST; GENE ACTIVATION; GENE INDUCTION; GENE SILENCING; IMMUNE DYSREGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; GENETICS; HUMAN; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; TUMOR CELL LINE;

MUS;

ANIMALS; CELL LINE, TUMOR; CYTOKINES; HUMANS; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; PROTEIN KINASES; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 70350004037     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.004184     Document Type: Article

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