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Volumn 276, Issue 21, 2009, Pages 6312-6323

A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A

Author keywords

Brainstem; Coaggregation; STAT5A splicing variant; Suppression of STAT5A activity

Indexed keywords

COMPLEMENTARY DNA; PROLACTIN; PROLINE; SERINE; STAT5A PROTEIN; THREONINE;

EID: 70349961479     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07339.x     Document Type: Article
Times cited : (6)

References (33)
  • 1
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE Jr., Kerr IM Stark GR (1994) Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415 1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell, Jr.J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 2
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • Levy DE Darnell JE Jr. (2002) Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 3, 651 662.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell, Jr.J.E.2
  • 3
    • 0030046753 scopus 로고    scopus 로고
    • STATs: Signal transducers and activators of transcription
    • Ihle JN (1996) STATs: signal transducers and activators of transcription. Cell 84, 331 334.
    • (1996) Cell , vol.84 , pp. 331-334
    • Ihle, J.N.1
  • 4
    • 0032191341 scopus 로고    scopus 로고
    • STAT structure and function in signaling
    • Hoey T Schindler U (1998) STAT structure and function in signaling. Curr Opin Genet Dev 8, 582 587.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 582-587
    • Hoey, T.1    Schindler, U.2
  • 6
    • 0036214521 scopus 로고    scopus 로고
    • PRL activates the cyclin D1 promoter via the Jak2/Stat pathway
    • Brockman JL, Schroeder MD Schuler LA (2002) PRL activates the cyclin D1 promoter via the Jak2/Stat pathway. Mol Endocrinol 16, 774 784.
    • (2002) Mol Endocrinol , vol.16 , pp. 774-784
    • Brockman, J.L.1    Schroeder, M.D.2    Schuler, L.A.3
  • 7
    • 0030765924 scopus 로고    scopus 로고
    • Jaks, STATs, cytokine signal transduction, and immunoregulation: Are we there yet?
    • O'Shea JJ (1997) Jaks, STATs, cytokine signal transduction, and immunoregulation: are we there yet? Immunity 7, 1 11.
    • (1997) Immunity , vol.7 , pp. 1-11
    • O'Shea, J.J.1
  • 8
    • 34249668897 scopus 로고    scopus 로고
    • STAT5A/B activity is required in the developing forebrain and spinal cord
    • Markham K, Schuurmans C Weiss S (2007) STAT5A/B activity is required in the developing forebrain and spinal cord. Mol Cell Neurosci 35, 272 282.
    • (2007) Mol Cell Neurosci , vol.35 , pp. 272-282
    • Markham, K.1    Schuurmans, C.2    Weiss, S.3
  • 13
    • 37349043000 scopus 로고    scopus 로고
    • Developmental expression and serotonergic regulation of relaxin 3/INSL7 in the nucleus incertus of rat brain
    • Miyamoto Y, Watanabe Y Tanaka M (2008) Developmental expression and serotonergic regulation of relaxin 3/INSL7 in the nucleus incertus of rat brain. Regul Pept 145, 54 59.
    • (2008) Regul Pept , vol.145 , pp. 54-59
    • Miyamoto, Y.1    Watanabe, Y.2    Tanaka, M.3
  • 14
    • 62849097825 scopus 로고    scopus 로고
    • Regulation of relaxin 3 gene expression via cAMP-PKA in a neuroblastoma cell line
    • Tanaka M, Watanabe Y Yoshimoto K (2009) Regulation of relaxin 3 gene expression via cAMP-PKA in a neuroblastoma cell line. J Neurosci Res 87, 820 829.
    • (2009) J Neurosci Res , vol.87 , pp. 820-829
    • Tanaka, M.1    Watanabe, Y.2    Yoshimoto, K.3
  • 15
    • 0033544961 scopus 로고    scopus 로고
    • Functional characterization of the intermediate isoform of the human prolactin receptor
    • Kline JB, Roehrs H Clevenger CV (1999) Functional characterization of the intermediate isoform of the human prolactin receptor. J Biol Chem 274, 35461 35468.
    • (1999) J Biol Chem , vol.274 , pp. 35461-35468
    • Kline, J.B.1    Roehrs, H.2    Clevenger, C.V.3
  • 16
    • 41049117603 scopus 로고    scopus 로고
    • Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporter
    • Fang F, Antico G, Zheng J Clevenger CV (2008) Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporter. BMC Biotechnol 8, 11.
    • (2008) BMC Biotechnol , vol.8 , pp. 11
    • Fang, F.1    Antico, G.2    Zheng, J.3    Clevenger, C.V.4
  • 17
    • 33750040230 scopus 로고    scopus 로고
    • Structure, function, and regulation of STAT proteins
    • Lim CP Cao X (2006) Structure, function, and regulation of STAT proteins. Mol Biosyst 2, 536 550.
    • (2006) Mol Biosyst , vol.2 , pp. 536-550
    • Lim, C.P.1    Cao, X.2
  • 19
    • 0032520260 scopus 로고    scopus 로고
    • Carboxyl-truncated STAT5β is generated by a nucleus-associated serine protease in early hematopoietic progenitors
    • Meyer J, Jücker M, Ostertag W Stocking C (1998) Carboxyl-truncated STAT5β is generated by a nucleus-associated serine protease in early hematopoietic progenitors. Blood 91, 1901 1908.
    • (1998) Blood , vol.91 , pp. 1901-1908
    • Meyer, J.1    Jücker, M.2    Ostertag, W.3    Stocking, C.4
  • 20
    • 0037457078 scopus 로고    scopus 로고
    • Naturally occurring dominant-negative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells
    • Yamashita H, Iwase H, Toyama T Fujii Y (2003) Naturally occurring dominant-negative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells. Oncogene 22, 1638 1652.
    • (2003) Oncogene , vol.22 , pp. 1638-1652
    • Yamashita, H.1    Iwase, H.2    Toyama, T.3    Fujii, Y.4
  • 24
    • 48749100692 scopus 로고    scopus 로고
    • Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL
    • Oberdoerffer S, Moita LF, Neems D, Freitas RP, Hacohen N Rao A (2008) Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL. Science 321, 686 691.
    • (2008) Science , vol.321 , pp. 686-691
    • Oberdoerffer, S.1    Moita, L.F.2    Neems, D.3    Freitas, R.P.4    Hacohen, N.5    Rao, A.6
  • 25
    • 34247102713 scopus 로고    scopus 로고
    • Nuclear translocation of the transcription factor STAT5 in the rat brain after systemic leptin administration
    • Mütze J, Roth J, Gerstberger R Hübschle T (2007) Nuclear translocation of the transcription factor STAT5 in the rat brain after systemic leptin administration. Neurosci Lett 417, 286 291.
    • (2007) Neurosci Lett , vol.417 , pp. 286-291
    • Mütze, J.1    Roth, J.2    Gerstberger, R.3    Hübschle, T.4
  • 26
    • 33750361540 scopus 로고    scopus 로고
    • A century-old debate on protein aggregation and neurodegeneration enters the clinic
    • Lansbury PT Lashuel HA (2006) A century-old debate on protein aggregation and neurodegeneration enters the clinic. Nature 443, 774 779.
    • (2006) Nature , vol.443 , pp. 774-779
    • Lansbury, P.T.1    Lashuel, H.A.2
  • 27
    • 0034578389 scopus 로고    scopus 로고
    • Aggresomes, inclusion bodies and protein aggregation
    • Kopito RR (2000) Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol 10, 524 530.
    • (2000) Trends Cell Biol , vol.10 , pp. 524-530
    • Kopito, R.R.1
  • 28
    • 1242338856 scopus 로고    scopus 로고
    • Huntingtin-protein interactions and the pathogenesis of Huntington's disease
    • Li SH Li XJ (2004) Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet 20, 146 154.
    • (2004) Trends Genet , vol.20 , pp. 146-154
    • Li, S.H.1    Li, X.J.2
  • 29
    • 40949135766 scopus 로고    scopus 로고
    • Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor
    • Yamanaka T, Miyazaki H, Oyama F, Kurosawa M, Washizu C, Doi H Nukina N (2008) Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor. EMBO J 27, 827 839.
    • (2008) EMBO J , vol.27 , pp. 827-839
    • Yamanaka, T.1    Miyazaki, H.2    Oyama, F.3    Kurosawa, M.4    Washizu, C.5    Doi, H.6    Nukina, N.7
  • 32
    • 33846033496 scopus 로고    scopus 로고
    • Differential effects of progestogens, by type and regimen, on estrogen-metabolizing enzymes in human breast cancer cells
    • Xu B, Kitawaki J, Koshiba H, Ishihara H, Kiyomizu M, Teramoto M, Kitaoka Y Honjo H (2007) Differential effects of progestogens, by type and regimen, on estrogen-metabolizing enzymes in human breast cancer cells. Maturitas 56, 142 152.
    • (2007) Maturitas , vol.56 , pp. 142-152
    • Xu, B.1    Kitawaki, J.2    Koshiba, H.3    Ishihara, H.4    Kiyomizu, M.5    Teramoto, M.6    Kitaoka, Y.7    Honjo, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.