Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?

British Journal of Pharmacology

Volumn 157, Issue 3, 2009, Pages 331-333

  Yue, Jiang ^a,b   Peng, Renxiu ^a  

^a WUHAN UNIVERSITY   (China)

^b NONE   (China)

Author keywords

Hepatotoxicity; Isoniazid; Rifampicin compilation

Indexed keywords

4 NITROPHENOL HYDROXYLASE; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; DEXAMETHASONE; ISONIAZID; KETOCONAZOLE; MESSENGER RNA; OXYGENASE; RIFAMPICIN; TROLEANDOMYCIN; UNCLASSIFIED DRUG; TUBERCULOSTATIC AGENT;

DISEASE EXACERBATION; DRUG METABOLISM; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; LIVER CELL; LIVER TOXICITY; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; BIOSYNTHESIS; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; PATHOLOGY; RAT;

ANIMALS; ANTITUBERCULAR AGENTS; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 CYP3A; HEPATOCYTES; HUMANS; ISONIAZID; RATS; RNA, MESSENGER;

EID: 70349902917     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00173.x     Document Type: Note

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