Assembly of substituted 1H-benzimidazoles and 1,3-dihydrobenzimidazol-2- ones via CuI/L-proline catalyzed coupling of aqueous ammonia with 2-iodoacetanilides and 2-iodophenylcarbamates

Journal of Organic Chemistry

Volumn 74, Issue 20, 2009, Pages 7974-7977

  Diao, Xiaoqiong ^a   Wang, Yuji ^a   Jiang, Yongwen ^b   Ma, Dawei ^b  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1H-BENZIMIDAZOLES; ACIDIC CONDITIONS; AQUEOUS AMMONIA; ARYLAMINATION; CATALYZED COUPLING; CHEMICAL EQUATIONS; HETEROCYCLES; IN-SITU; REACTION CONDITIONS; ROOM TEMPERATURE;

AMINES; AMMONIA; CHEMICAL REACTIONS; ESTERS; FUNCTIONAL GROUPS; KETONES;

DRUG PRODUCTS;

1,3 DIHYDROBENZIMIDAZOL 2 ONE; 1H BENZIMIDAZOLE; 2 (4 CHLOROPHENYL) 6 NITRO 1H BENZIMIDAZOLE; 2 OXO N PROPYL 2,3 DIHYDRO 1H BENZO[D]IMIDAZOLE 5 CARBOXAMIDE; 4,6 DIMETHYL 1H BENZIMIDAZOL 2(3H) ONE; 5 ACETYL 1H BENZIMIDAZOLE 2(3H) ONE; 6 FLUORO 2 (FURAN 2 YL) 1H BENZIMIDAZOLE; ACETANILIDE DERIVATIVE; AMMONIA; BENZIMIDAZOLE DERIVATIVE; CARBAMIC ACID DERIVATIVE; CUPROUS ION; METHYL 2 PROPYL 1H BENZIMIDAZOLE 6 CARBOXYLATE; PROLINE; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; CATALYST; CYCLIZATION; DRUG SYNTHESIS; ONE POT SYNTHESIS; ROOM TEMPERATURE; SUBSTITUTION REACTION;

ACETANILIDES; AMMONIA; BENZIMIDAZOLES; CATALYSIS; COPPER; IODIDES; IODINE; MOLECULAR STRUCTURE; PHENYLCARBAMATES; PROLINE; WATER;

EID: 70349866012     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9017183     Document Type: Article

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