Conversion of sterically hindered diacylated 1,2-phenylenediamines into 2-substituted benzimidazoles

Chemical and Pharmaceutical Bulletin

Volumn 53, Issue 5, 2005, Pages 492-497

  Charton, Julie ^a   Girault Mizzi, Sophie ^a   Sergheraert, Christian ^a  

^a CNRS   (France)

Author keywords

Benzimidazole; Cyclization; Mechanism

Indexed keywords

1,2 PHENYLENEDIAMINE; 2 (1 PHENYLETHYL) 1H BENZOIMIDAZOLE; 2 (1,2,3,4 TETRAHYDRONAPHTHALEN 2 YL) 1H BENZOIMIDAZOLE; 2 (4 PROPYLPHENYL) 1H BENZOIMIDAZOLE; 2 (9H FLUOREN 9 YL) 1H BENZOIMIDAZOLE; 2 (CYCLOHEXYLPHENYLMETHYL) 1H BENZOIMIDAZOLE; 2 (CYCLOPENTYLPHENYLMETHYL) 1H BENZOIMIDAZOLE; 2 BENZHYDRYL 1H BENZOIMIDAZOLE; 2 BENZYL 1H BENZOIMIDAZOLE; 2 BIPHENYL 2 YL 1H BENZOIMIDAZOLE; 2 BIPHENYL 4 YL 1H BENZOIMIDAZOLE; 2 CYCLOHEXYL N [2 (2 CYCLOHEXYLACETYLAMINO)PHENYL] 2 PHENYLACETAMIDE; 2 CYCLOHEXYL N [2 (2 CYCLOPENTYL 2 PHENYLACETYLAMINO)PHENYL] 2 PHENYLACETAMIDE; 2 CYCLOHEXYLMETHYL 1H BENZOIMIDAZOLE; 2 DICYCLOHEXYLMETHYL 1H BENZOIMIDAZOLE; 2 ETHYL 1H BENZOIMIDAZOLE; 2 METHYL 1H BENZOIMIDAZOLE; 2 PROPYL 1H BENZOIMIDAZOLE; 2 TERT BUTYL 1H BENZOIMIDAZOLE; 2,2 DICYCLOHEXYL N (2 DIPHENYLACETYLAMINOPHENYL)ACETAMIDE; 2,2 DICYCLOHEXYL N (2 PHENYLACETYLAMINOPHENYL)ACETAMIDE; 2,2 DICYCLOHEXYL N [2 (2,2 DICYCLOHEXYLACETYLAMINO)PHENYL]ACETAMIDE; 2,2 DIPHENYL N (2 PHENYLACETYLAMINOPHENYL)ACETAMIDE; BENZIMIDAZOLE DERIVATIVE; N (2 ACETYLAMINOPHENYL) 2,2 DICYCLOHEXYLACETAMIDE; N (2 ACETYLAMINOPHENYL) 2,2 DIPHENYLACETAMIDE; N (2 DIPHENYLACETYLAMINOPHENYL) 2,2 DIMETHYLPROPIONAMIDE; N (2 DIPHENYLACETYLAMINOPHENYL) 2,2 DIPHENYLACETAMIDE; N (2 DIPHENYLACETYLAMINOPHENYL)BUTYRAMIDE; N (2 DIPHENYLACETYLAMINOPHENYL)PROPIONAMIDE; N [2 (2 CYCLOHEXYLACETYLAMINO)PHENYL] 2,2 DIPHENYLACETAMIDE; N [2 (2,2 DICYCLOHEXYLACETYLAMINO)PHENYL]BUTYRAMIDE; N [2 (2,2 DICYCLOHEXYLACETYLAMINO)PHENYL]PROPIONAMIDE; TOLUENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CYCLIZATION; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STEREOSPECIFICITY;

ACETYLATION; BENZIMIDAZOLES; PHENYLENEDIAMINES; STEREOISOMERISM;

EID: 19644379034     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.53.492     Document Type: Article

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