메뉴 건너뛰기




Volumn 90, Issue 1, 2009, Pages 19-35

Cellular reprogramming and pluripotency induction

Author keywords

Cellular reprogramming; Induced pluripotency; IPS cells; Stem cells

Indexed keywords

CELL CLONING; CELL LINE; CELL NUCLEUS TRANSPLANTATION; DEVELOPMENTAL BIOLOGY; DEVELOPMENTAL STAGE; EMBRYONIC STEM CELL; EPIGENETICS; GENE ACTIVITY; GENE EXPRESSION; HUMAN; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW; SOMATIC CELL; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; MEDICAL RESEARCH; NUCLEAR REPROGRAMMING;

EID: 70349561272     PISSN: 00071420     EISSN: 14718391     Source Type: Journal    
DOI: 10.1093/bmb/ldp011     Document Type: Review
Times cited : (10)

References (69)
  • 2
    • 0022054003 scopus 로고
    • Hartsoeker's homonculus: A corrective note
    • Hill KA (1985) Hartsoeker's homonculus: a corrective note. J Hist Behav Sci, 21, 178-179.
    • (1985) J Hist Behav Sci , vol.21 , pp. 178-179
    • Hill, K.A.1
  • 4
    • 10544222277 scopus 로고
    • Beiträge zur Entwickelungsmechanik des Embryo. Uber die künstliche Hervorbringung 'halber' Embryonen durch Zerstörung einer der beiden ersten Furchungskugeln. sowie über die Nachentwickelung (Postgeneration) der fehlenden Kö rperhälfte: Gesammelte Abhandlungen II
    • Roux W (1888) Beiträge zur Entwickelungsmechanik des Embryo. Uber die künstliche Hervorbringung 'halber' Embryonen durch Zerstörung einer der beiden ersten Furchungskugeln, sowie über die Nachentwickelung (Postgeneration) der fehlenden Kö rperhälfte: Gesammelte Abhandlungen II. Virchows Archiv, 114, 419-521.
    • (1888) Virchows Archiv , vol.114 , pp. 419-521
    • Roux, W.1
  • 5
    • 0000887517 scopus 로고
    • Entwicklungsmechanische Studien I. Der Wert der ersten beiden Furchungszellen in der Echinodermenentwickelung. Experimentelle Erzeugung von Teil und Doppelbildungen
    • Driesch H (1891) Entwicklungsmechanische Studien I. Der Wert der ersten beiden Furchungszellen in der Echinodermenentwickelung. Experimentelle Erzeugung von Teil und Doppelbildungen. Ztschr f Wiss Zool, 53, 160-183.
    • (1891) Ztschr F Wiss Zool , vol.53 , pp. 160-183
    • Driesch, H.1
  • 6
    • 9544247527 scopus 로고
    • Half embryos and whole embryos from one of the first two blastomeres
    • Morgan TH (1895) Half embryos and whole embryos from one of the first two blastomeres. Anat Anz, 10, 623-638.
    • (1895) Anat Anz , vol.10 , pp. 623-638
    • Morgan, T.H.1
  • 8
    • 0343754332 scopus 로고
    • Die Entwicklung seitlicher und dorso-ventraler Keimhälften bei ver-zö gerter Kernversorgung
    • Spemann H (1928) Die Entwicklung seitlicher und dorso-ventraler Keimhälften bei ver-zö gerter Kernversorgung. Ztschr f Wiss Zool, 132, 105-134.
    • (1928) Ztschr F Wiss Zool , vol.132 , pp. 105-134
    • Spemann, H.1
  • 9
    • 0000042464 scopus 로고
    • Transplantation of living nuclei from blastula cells into enucleated frogs' eggs
    • Briggs R, King TJ (1952) Transplantation of living nuclei from blastula cells into enucleated frogs' eggs. Proc Natl Acad Sci U S A, 38, 455-463.
    • (1952) Proc Natl Acad Sci U S A , vol.38 , pp. 455-463
    • Briggs, R.1    King, T.J.2
  • 10
    • 0000155376 scopus 로고
    • The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles
    • Gurdon JB (1962) The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles. J Embryol Exp Morphol, 10, 622-640.
    • (1962) J Embryol Exp Morphol , vol.10 , pp. 622-640
    • Gurdon, J.B.1
  • 11
    • 0037478841 scopus 로고    scopus 로고
    • The first half-century of nuclear transplantation
    • Gurdon JB, Byrne JA (2003) The first half-century of nuclear transplantation. Proc Natl Acad Sci U S A, 100, 8048-8052.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8048-8052
    • Gurdon, J.B.1    Byrne, J.A.2
  • 12
    • 8644231848 scopus 로고    scopus 로고
    • Nuclei of embryonic stem cells reprogram somatic cells
    • Do JT, Scholer HR (2004) Nuclei of embryonic stem cells reprogram somatic cells. Stem Cells, 22, 941-949.
    • (2004) Stem Cells , vol.22 , pp. 941-949
    • Do, J.T.1    Scholer, H.R.2
  • 13
    • 0029967424 scopus 로고    scopus 로고
    • Sheep cloned by nuclear transfer from a cultured cell line
    • Campbell KH, McWhir J, Ritchie WA, Wilmut I (1996) Sheep cloned by nuclear transfer from a cultured cell line. Nature, 380, 64-66.
    • (1996) Nature , vol.380 , pp. 64-66
    • Campbell, K.H.1    McWhir, J.2    Ritchie, W.A.3    Wilmut, I.4
  • 14
  • 15
    • 0032560827 scopus 로고    scopus 로고
    • Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei
    • Wakayama T, Perry AC, Zuccotti M, Johnson KR, Yanagimachi R (1998) Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature, 394, 369-374.
    • (1998) Nature , vol.394 , pp. 369-374
    • Wakayama, T.1    Perry, A.C.2    Zuccotti, M.3    Johnson, K.R.4    Yanagimachi, R.5
  • 16
    • 0037186519 scopus 로고    scopus 로고
    • Monoclonal mice generated by nuclear transfer from mature B and T donor cells
    • Hochedlinger K, Jaenisch R (2002) Monoclonal mice generated by nuclear transfer from mature B and T donor cells. Nature, 415, 1035-1038.
    • (2002) Nature , vol.415 , pp. 1035-1038
    • Hochedlinger, K.1    Jaenisch, R.2
  • 17
    • 1542347544 scopus 로고    scopus 로고
    • Mice cloned from olfactory sensory neurons
    • Eggan K, Baldwin K, Tackett M et al. (2004) Mice cloned from olfactory sensory neurons. Nature, 428, 44-49.
    • (2004) Nature , vol.428 , pp. 44-49
    • Eggan, K.1    Baldwin, K.2    Tackett, M.3
  • 19
    • 3543073392 scopus 로고    scopus 로고
    • Reprogramming of a melanoma genome by nuclear transplantation
    • Hochedlinger K, Blelloch R, Brennan C et al. (2004) Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev, 18, 1875-1885.
    • (2004) Genes Dev , vol.18 , pp. 1875-1885
    • Hochedlinger, K.1    Blelloch, R.2    Brennan, C.3
  • 20
    • 0031768294 scopus 로고    scopus 로고
    • Large offspring syndrome in cattle and sheep
    • Young LE, Sinclair KD, Wilmut I. (1998) Large offspring syndrome in cattle and sheep. Rev Reprod, 3, 155-163.
    • (1998) Rev Reprod , vol.3 , pp. 155-163
    • Young, L.E.1    Sinclair, K.D.2    Wilmut, I.3
  • 21
    • 0035134738 scopus 로고    scopus 로고
    • Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture
    • Young LE, Fernandes K, McEvoy TG et al. (2001) Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture. Nat Genet, 27, 153-154.
    • (2001) Nat Genet , vol.27 , pp. 153-154
    • Young, L.E.1    Fernandes, K.2    McEvoy, T.G.3
  • 24
    • 0038185327 scopus 로고    scopus 로고
    • Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei
    • Bortvin A, Eggan K, Skaletsky H et al. (2003) Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development, 130, 1673-1680.
    • (2003) Development , vol.130 , pp. 1673-1680
    • Bortvin, A.1    Eggan, K.2    Skaletsky, H.3
  • 25
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev, 16, 6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 26
    • 0035234557 scopus 로고    scopus 로고
    • Genomic imprinting: Parental influence on the genome
    • Reik W, Walter J (2001) Genomic imprinting: parental influence on the genome. Nat Rev Genet, 2, 21-32.
    • (2001) Nat Rev Genet , vol.2 , pp. 21-32
    • Reik, W.1    Walter, J.2
  • 28
    • 0036127638 scopus 로고    scopus 로고
    • Cloned mice have an obese phenotype not transmitted to their offspring
    • Tamashiro KL, Wakayama T, Akutsu H et al. (2002) Cloned mice have an obese phenotype not transmitted to their offspring. Nat Med, 8, 262-267.
    • (2002) Nat Med , vol.8 , pp. 262-267
    • Tamashiro, K.L.1    Wakayama, T.2    Akutsu, H.3
  • 29
    • 0000727065 scopus 로고
    • Spontaneous testicular teratomas in an inbred strain of mice
    • Stevens LC, Little CC (1954) Spontaneous testicular teratomas in an inbred strain of mice. Proc Natl Acad Sci U S A, 40, 1080-1087.
    • (1954) Proc Natl Acad Sci U S A , vol.40 , pp. 1080-1087
    • Stevens, L.C.1    Little, C.C.2
  • 30
    • 84883845299 scopus 로고
    • Multipotentiality of single embryonal carcinoma cells
    • Kleinsmith LJ, Pierce GB Jr (1964) Multipotentiality of single embryonal carcinoma cells. Cancer Res, 24, 1544-1551.
    • (1964) Cancer Res , vol.24 , pp. 1544-1551
    • Kleinsmith, L.J.1    Jr P.Gb2
  • 31
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature, 292, 154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 32
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin GR (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A, 78, 7634-7638.
    • (1981) Proc Natl Acad Sci U S A , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 33
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. (1998) Embryonic stem cell lines derived from human blastocysts. Science, 282, 1145-1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 34
    • 2642552297 scopus 로고    scopus 로고
    • Origins of mammalian hematopoiesis: In vivo paradigms and in vitro models
    • Lensch MW, Daley GQ (2004) Origins of mammalian hematopoiesis: in vivo paradigms and in vitro models. Curr Top Dev Biol, 60, 127-196.
    • (2004) Curr Top Dev Biol , vol.60 , pp. 127-196
    • Lensch, M.W.1    Daley, G.Q.2
  • 35
    • 33645505915 scopus 로고    scopus 로고
    • Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells
    • Lensch MW, Daley GQ (2006) Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells. Blood, 107, 2605-2612.
    • (2006) Blood , vol.107 , pp. 2605-2612
    • Lensch, M.W.1    Daley, G.Q.2
  • 37
    • 20444435917 scopus 로고    scopus 로고
    • Ensuring access to education and services on infertility for the under-served
    • Jenkins RL (2005) Ensuring access to education and services on infertility for the under-served. J Natl Cancer Inst Monogr, 34, 101-103.
    • (2005) J Natl Cancer Inst Monogr , vol.34 , pp. 101-103
    • Jenkins, R.L.1
  • 38
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • Dimos JT, Rodolfa KT, Niakan KK et al. (2008) Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science, 321, 1218-1221.
    • (2008) Science , vol.321 , pp. 1218-1221
    • Dimos, J.T.1    Rodolfa, K.T.2    Niakan, K.K.3
  • 39
    • 50549089957 scopus 로고    scopus 로고
    • Disease-specific induced pluripotent stem cells
    • Park IH, Arora N, Huo H et al. (2008) Disease-specific induced pluripotent stem cells. Cell, 134, 877-886.
    • (2008) Cell , vol.134 , pp. 877-886
    • Park, I.H.1    Arora, N.2    Huo, H.3
  • 40
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 126, 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 41
    • 34249863603 scopus 로고    scopus 로고
    • Strategies and new developments in the generation of patient-specific pluripotent stem cells
    • Yamanaka S (2007) Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell, 1, 39-49.
    • (2007) Cell Stem Cell , vol.1 , pp. 39-49
    • Yamanaka, S.1
  • 42
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H, Miyazaki J, Smith AG (2000) Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet, 24, 372-376.
    • (2000) Nat Genet , vol.24 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 43
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell, 122, 947-956.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 44
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh YH, Wu Q, Chew JL et al. (2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet, 38, 431-440.
    • (2006) Nat Genet , vol.38 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3
  • 45
    • 40749104852 scopus 로고    scopus 로고
    • An extended transcriptional network for pluripotency of embryonic stem cells
    • Kim J, Chu J, Shen X et al. (2008) An extended transcriptional network for pluripotency of embryonic stem cells. Cell, 132, 1049-1061.
    • (2008) Cell , vol.132 , pp. 1049-1061
    • Kim, J.1    Chu, J.2    Shen, X.3
  • 46
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripo-tent stem cells
    • Okita K, Ichisaka T, Yamanaka S (2007) Generation of germline-competent induced pluripo-tent stem cells. Nature, 448, 313-317.
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 47
    • 34249909232 scopus 로고    scopus 로고
    • Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
    • Maherali N, Sridharan R, Xie W et al. (2007) Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell, 1, 55-70.
    • (2007) Cell Stem Cell , vol.1 , pp. 55-70
    • Maherali, N.1    Sridharan, R.2    Xie, W.3
  • 49
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell, 131, 861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 50
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K et al. (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science, 318, 1917-1920.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 51
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripo-tency with defined factors
    • Park IH, Zhao R, West JA et al. (2008) Reprogramming of human somatic cells to pluripo-tency with defined factors. Nature, 451, 141-146.
    • (2008) Nature , vol.451 , pp. 141-146
    • Park, I.H.1    Zhao, R.2    West, J.A.3
  • 52
    • 41349090105 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells from dermal fibroblasts
    • Lowry WE, Richter L, Yachechko et al. (2008) Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci U S A, 105, 2883-2888.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2883-2888
    • Lowry, W.E.1    Yachechko, R.L.2
  • 53
    • 0346250854 scopus 로고    scopus 로고
    • The Transcriptome Profile of Human Embryonic Stem Cells as Defined by SAGE
    • Richards M, Tan SP, Tan JH, Chan WK, Bongso A (2004) The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells, 22, 51-64. (Pubitemid 38018781)
    • (2004) Stem Cells , vol.22 , Issue.1 , pp. 51-64
    • Richards, M.1    Tan, S.-P.2    Tan, J.-H.3    Chan, W.-K.4    Bongso, A.5
  • 54
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • Viswanathan SR, Daley GQ, Gregory RI (2008) Selective blockade of microRNA processing by Lin28. Science, 320, 97-100.
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 55
    • 34548420596 scopus 로고    scopus 로고
    • Teratoma formation assays with human embryonic stem cells: A rationale for one type of human-animal chimera
    • Lensch MW, Schlaeger TM, Zon LI, Daley GQ (2007) Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. Cell Stem Cell, 1, 253-258.
    • (2007) Cell Stem Cell , vol.1 , pp. 253-258
    • Lensch, M.W.1    Schlaeger, T.M.2    Zon, L.I.3    Daley, G.Q.4
  • 56
    • 0037023568 scopus 로고    scopus 로고
    • Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy
    • Rideout WM 3rd, Hochedlinger K, Kyba M, Daley GQ, Jaenisch R (2002) Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy. Cell, 109, 17-27.
    • (2002) Cell , vol.109 , pp. 17-27
    • Rideout III, W.M.1    Hochedlinger, K.2    Kyba, M.3    Daley, G.Q.4    Jaenisch, R.5
  • 57
    • 37549030199 scopus 로고    scopus 로고
    • Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
    • Hanna J, Wernig M, Markoulaki S et al. (2007) Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science, 318, 1920-1923.
    • (2007) Science , vol.318 , pp. 1920-1923
    • Hanna, J.1    Wernig, M.2    Markoulaki, S.3
  • 58
    • 56549127713 scopus 로고    scopus 로고
    • Guidelines and techniques for the generation of induced pluripotent stem cells
    • Maherali N, Hochedlinger K (2008) Guidelines and techniques for the generation of induced pluripotent stem cells. Cell Stem Cell, 3, 595-605.
    • (2008) Cell Stem Cell , vol.3 , pp. 595-605
    • Maherali, N.1    Hochedlinger, K.2
  • 59
    • 48349095740 scopus 로고    scopus 로고
    • Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
    • Kim JB, Zaehres H, Wu G et al. (2008) Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature, 454, 646-650.
    • (2008) Nature , vol.454 , pp. 646-650
    • Kim, J.B.1    Zaehres, H.2    Wu, G.3
  • 60
    • 48149107133 scopus 로고    scopus 로고
    • Wnt signaling promotes reprogramming of somatic cells to pluripotency
    • Marson A, Foreman R, Chevalier B et al. (2008) Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell Stem Cell, 3, 132-135.
    • (2008) Cell Stem Cell , vol.3 , pp. 132-135
    • Marson, A.1    Foreman, R.2    Chevalier, B.3
  • 62
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • Ying QL, Wray J, Nichols J et al. (2008) The ground state of embryonic stem cell self-renewal. Nature, 453, 519-523.
    • (2008) Nature , vol.453 , pp. 519-523
    • Ying, Q.L.1    Wray, J.2    Nichols, J.3
  • 63
    • 46449094276 scopus 로고    scopus 로고
    • Dissecting direct reprogramming through inte-grative genomic analysis
    • Mikkelsen TS, Hanna J, Zhang X et al. (2008) Dissecting direct reprogramming through inte-grative genomic analysis. Nature, 454, 49-55.
    • (2008) Nature , vol.454 , pp. 49-55
    • Mikkelsen, T.S.1    Hanna, J.2    Zhang, X.3
  • 64
    • 58549096370 scopus 로고    scopus 로고
    • Reprogramming of murine and human somatic cells using a single polycistronic vector
    • Carey BW, Markoulaki S, Hanna J et al. (2009) Reprogramming of murine and human somatic cells using a single polycistronic vector. Proc Natl Acad Sci U S A, 106, 157-162.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 157-162
    • Carey, B.W.1    Markoulaki, S.2    Hanna, J.3
  • 65
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S (2008) Generation of mouse induced pluripotent stem cells without viral vectors. Science, 322, 949-953.
    • (2008) Science , vol.322 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3    Ichisaka, T.4    Yamanaka, S.5
  • 66
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K (2008) Induced pluripotent stem cells generated without viral integration. Science, 322, 945-949.
    • (2008) Science , vol.322 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3    Weir, G.4    Hochedlinger, K.5
  • 67
    • 42649130264 scopus 로고    scopus 로고
    • Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
    • Wernig M, Zhao JP, Pruszak J et al. (2008) Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci U S A, 105, 5856-5861.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 5856-5861
    • Wernig, M.1    Zhao, J.P.2    Pruszak, J.3
  • 68
    • 0023663888 scopus 로고
    • Expression of a single transfected cDNA converts fibroblasts to myoblasts
    • Davis RL, Weintraub H, Lassar AB (1987) Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell, 51, 987-1000.
    • (1987) Cell , vol.51 , pp. 987-1000
    • Davis, R.L.1    Weintraub, H.2    Lassar, A.B.3
  • 69
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
    • Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA (2008) In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature, 455, 627-632.
    • (2008) Nature , vol.455 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3    Rajagopal, J.4    Melton, D.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.