Syk: A novel target for treatment of inflammation in lung disease

Inflammation and Allergy - Drug Targets

Volumn 8, Issue 2, 2009, Pages 87-95

  Sanderson, Michael P ^a   Lau, Christine W ^b   Schnapp, Andreas ^a   Chow, Chung Wai ^b  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Airway epithelium; Airway inflammation; Allergic rhinitis; Human rhinovirus; Rheumatoid arthritis; Syk inhibitors; Syk tyrosine kinase

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; PROTEIN KINASE SYK; PROTEIN KINASE SYK INHIBITOR; R 112; R 406; UNCLASSIFIED DRUG;

ALLERGIC RHINITIS; ANAPHYLACTIC SHOCK; ASTHMA; BIOCHEMICAL COMPOSITION; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; HOST PATHOGEN INTERACTION; HUMAN; HUMAN RHINOVIRUS; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNE RESPONSE; INFLAMMATORY CELL; INFLAMMATORY DISEASE; LUNG DISEASE; NONHUMAN; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; REGULATORY MECHANISM; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFLAMMATION; REVIEW; RHEUMATOID ARTHRITIS; RHINOVIRUS INFECTION; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; VIRUS ENTRY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CLINICAL TRIALS AS TOPIC; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKOCYTES; LUNG DISEASES, OBSTRUCTIVE; OXAZINES; PICORNAVIRIDAE INFECTIONS; PNEUMONIA, VIRAL; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; PYRIDINES; RESPIRATORY MUCOSA; RHINOVIRUS; SIGNAL TRANSDUCTION; VIRULENCE; VIRUS INTERNALIZATION;

EID: 70349490326     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152809788462626     Document Type: Review

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