Ligand-dependent activation of the chimeric tumor necrosis factor receptor-amyloid precursor protein (APP) reveals increased app processing and suppressed neuronal differentiation

NeuroSignals

Volumn 18, Issue 1, 2010, Pages 9-23

  Sim, Poh Ling ^a   Heese, Klaus ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Amyloid precursor protein; Alzheimer's disease; Differentiation; Neurodegeneration

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CYCLIN D1; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; PROTEIN NTRK1; PROTEIN P53; STAT3 PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 1B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; NERVE CELL DIFFERENTIATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHEOCHROMOCYTOMA; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL DIFFERENTIATION; CYCLIN D1; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GREEN FLUORESCENT PROTEINS; HUMANS; LIGANDS; NERVE GROWTH FACTOR; NEURITES; PC12 CELLS; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; RECEPTOR, TRKA; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT FUSION PROTEINS; THREONINE; TIME FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 70349418675     PISSN: 1424862X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000242425     Document Type: Article

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