Synthesis and evaluation of derrubone and select analogues

Journal of Organic Chemistry

Volumn 73, Issue 2, 2008, Pages 369-373

  Hastings, Jedidiah M ^a   Hadden, M Kyle ^a   Blagg, Brian S J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL EVALUATION; NATURAL PRODUCT;

CELLS; ENZYME ACTIVITY;

ENZYME INHIBITION;

3 (BENZO[D][1,3]DIOXOL 5 YL) 5,7 DIHYDROXY 4H CHROMEN 4 ONE; ANTINEOPLASTIC AGENT; DERRUBONE; HEAT SHOCK PROTEIN 90; NATURAL PRODUCT; UNCLASSIFIED DRUG; ISOFLAVONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BREAST CANCER; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INHIBITION KINETICS; PROTEIN DEGRADATION; STRUCTURE ACTIVITY RELATION; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DERRIS; DRUG EFFECT; STEREOISOMERISM; SYNTHESIS; TUMOR CELL LINE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; DERRIS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; ISOFLAVONES; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 40949091876     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo702366g     Document Type: Article

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