Derrubone, an inhibitor of the Hsp90 protein folding machinery

Journal of Natural Products

Volumn 70, Issue 12, 2007, Pages 2014-2018

  Hadden, M Kyle ^a   Galam, Lakshmi ^a   Gestwicki, Jason E ^c   Matts, Robert L ^b   Blagg, Brian S J ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DERRUBONE; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DERRIS; DRUG EFFECT; DRUG IDENTIFICATION; DRUG MECHANISM; IN VITRO STUDY; PROTEIN DEGRADATION;

ANIMALS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; ISOFLAVONES; LUCIFERASES, FIREFLY; MOLECULAR STRUCTURE; PROTEIN FOLDING; RABBITS; RETICULOCYTES;

EID: 38349059089     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np070190s     Document Type: Article

References (29)

1. Pearl, L. H.; Prodromou, C. Annu. Rev. Biochem. 2006, 75, 271-294.
2. Zhang, H.; Burrows, F. J. Mol. Med. 2004, 82, 488-499.
3. Pacey, S.; Banerji, U.; Judson, I.; Workman, P. Handb. Exp. Pharmacol. 2006, 172, 331-358.
4. Dou, F.; Netzer, W. J.; Tanemura, K.; Li, F.; Hartl, U.; Takashima, A.; Gouras, G. K.; Greengard, P.; Xu, H. Proc. Natl. Acad. Sci. 2002, 100, 721-726.
5. Ansar, S.; Burlison, J. A.; Hadden, M. K.; Yu, X. M.; Desino, K. E.; Bean, J.; Neckers, L.; Audus, K. A.; Holzbeierlein, J.; Michaelis, M. L.; Blagg, B. S. J. Bioorg. Med. Chem. Lett. 2007, 17, 1984-1990.
6. Shen, H. Y.; He, J. C.; Wang, Y.; Huang, Q. Y.; Chen, J. F. J. Biol. Chem. 2005, 280, 39962-39969.
7. Blagg, B. S. J.; Kerr, T. D. Med. Res. Rev. 2006, 26, 310-338.
8. Agatsuma, T.; Ogawa, H.; Akasaka, K.; Asai, A.; Yamashita, Y.; Mizukami, T.; Akinaga, S.; Saitoh, Y. Bioorg. Med. Chem. 2002, 10, 3445-3449.
9. Marcu, M. G.; Chadli, A.; Bouhouche, I.; Catelli, M.; Neckers, L. M. J. Biol. Chem. 2000, 275, 37181-37186.
10. Marcu, M. G.; Schulte, T. W.; Neckers, L. J. Natl. Cancer Inst. 2000, 92, 242-248.
11. Burlison, J. A.; Blagg, B. S. J. Org. Utt. 2006, 8, 4855-4858.
12. Galam, L.; Hadden, M. K.; Ma, Z.; Ye, Q.-Z.; Yun, B.-G.; Blagg, B. S. J.; Matts, R. L. Bioorg. Med. Chem. 2007, 15, 1939-1946.
13. Thulasiraman, V.; Matts, R. L. Biochemistry 1996, 35, 13443-13450.
14. East, A. J.; Ollis, W. D.; Wheeler, R. E. J. Chem. Soc. C: Org. 1969, 3, 365-374.
15. Jain, A. C.; Jain, S. M. Tetrahedron 1972, 28, 5063-5067.
16. Shao, J.; Grammatikakis, N.; Scroggins, B. T.; Uma, S.; Huang, W.; Chen, J.-J.; Hartson, S. D.; Matts, R. L. J. Biol. Chem. 2001, 276, 206-214.
17. Shao, J.; Hartson, S. D.; Matts, R. L. Biochemistry 2002, 41, 6770-6779.
18. Hieronymus, H.; Lamb, J.; Ross, K. N.; Peng, X. P.; Clement, C.; Rodina, A.; Nieto, M.; Du, J.; Stegmaier, K.; Raj, S. M.; Maloney, K. N.; Clardy, J.; Hahn, W. H.; Chiosis, G.; Golub, T. R. Cancer Cell 2006, 10, 321-330.
19. Uma, S.; Hartson, S. D.; Chen, J.-J.; Matts, R. L. J. Biol. Chem. 1997, 272, 11648-11656.
20. Hartson, S. D.; Thulasiraman, V.; Huang, W.; Whitesell, L.; Matts, R. L. Biochemistry 1999, 38, 3837-3849.
21. Kamal, A.; Thao, L.; Sensintaffar, J.; Zhang, L.; Boehm, M. F.; Fritz, L. C.; Burrows, F. J. Nature 2003, 425, 407-410.
22. Slamon, D. J.; Godolphin, W.; Jones, L. A.; Holt, J. A.; Wong, S. G.; Keith, D. E.; Levin, W. J.; Stuart, S. G.; Udove, J.; Ullrich, A. Science 1989, 244, 707-712.
23. Plosker, G. L.; Keam, S. J. Drugs 2006, 66, 449-475.
24. Ariazi, E. A.; Ariazi, J. L.; Cordera, F.; Jordan, V. C. Curr. Top. Med. Chem. 2006, 6, 181-202.
25. Thulasiraman, V.; Matts, R. L. In Methods in Molecular Biology: Bioluminescent Protocols; LaRossa, R., Ed.; Humana Press, Inc.: Totowa, NJ, 1997;Chapter 11.
26. Yun, B.-G.; Huang, W.; Leach, N.; Hartson, S. D.; Matts, R. L. Biochemistry 2004, 43, 8217-8229.
27. Prince, T.; Sun, L.; Matts, R. L. Biochemistry 2005, 44, 15287-15295.
28. Huezo, H.; Vilenchik, M.; Rosen, N.; Chiosis, G. Chem. Biol. 2003, 10, 629-634.
29. Chang, L.; Bertelsen, E. B.; Wisen, S.; Larsen, E. M.; Zuiderweg, E. R.; Gestwicki, J. E. Biochemistry 2007, in press.