Insights into lid movements of Burkholderia cepacia lipase inferred from molecular dynamics simulations

Proteins: Structure, Function and Bioinformatics

Volumn 77, Issue 3, 2009, Pages 509-523

  Barbe, Sophie ^a,b,c   Lafaquière, Vincent ^a,b,c   Guieysse, David ^a,b,c   Monsan, Pierre ^a,b,c,d   Remaud Siméon, Magali ^a,b,c   André, Isabelle ^a,b,c  

^a UNIVERSITÉ DE TOULOUSE   (France)

^b CNRS   (France)

^c UMR792 INGÉNIERIE DES SYSTÈMES BIOLOGIQUES ET DES PROCÉDÉS   (France)

^d INSTITUT UNIVERSITAIRE DE FRANCE   (France)

Author keywords

Burkholderia cepacia lipase; Conformational transition; Lid movement; Molecular dynamics; Protein activation; Protein flexibility; Solvent environment

Indexed keywords

BACTERIAL ENZYME; OCTANE; ORGANIC SOLVENT; TRIACYLGLYCEROL LIPASE; WATER;

ALPHA HELIX; ARTICLE; BURKHOLDERIA CEPACIA; CONFORMATIONAL TRANSITION; ENVIRONMENT; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STRUCTURE; MOLECULAR DYNAMICS; MUTATION; PRIORITY JOURNAL; SIMULATION;

BIOCHEMISTRY; BURKHOLDERIA CEPACIA; COMPUTATIONAL BIOLOGY; ENZYME INHIBITORS; LIPASE; MODELS, MOLECULAR; PHOSPHATES; PROTEIN CONFORMATION; PROTEINS; SOLVENTS; TIME FACTORS;

BURKHOLDERIA CEPACIA;

EID: 70349333394     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22462     Document Type: Article

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