Active serine involved in the stabilization of the active site loop in the Humicola lanuginosa lipase

Biochemistry

Volumn 37, Issue 36, 1998, Pages 12375-12383

  Peters, G H ^a,d   Svendsen, A ^b   Langberg, H ^b   Vind, J ^b   Patkar, S A ^b   Toxvaerd, S ^a   Kinnunen, P K J ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c UNIVERSITY OF HELSINKI   (Finland)

^d TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; TRIACYLGLYCEROL LIPASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STABILITY; ENZYME STRUCTURE; MOLECULAR CLONING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ALANINE; BINDING SITES; DIMYRISTOYLPHOSPHATIDYLCHOLINE; ENZYME STABILITY; LIPASE; LIPOSOMES; MITOSPORIC FUNGI; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PHOSPHATIDYLGLYCEROLS; PROTEIN STRUCTURE, SECONDARY; SERINE; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS;

BACTERIA (MICROORGANISMS); HUMICOLA; THERMOMYCES LANUGINOSUS;

EID: 0032497412     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972883l     Document Type: Article

References (78)

1. Derewenda, U., Swenson, L., Wei, Y., Green, R., Kobos, P. M., Joerger, R., Haas, M. J., and Derewenda, Z. S. (1994) J. Lipid Res. 35, 524-534.
2. Brzozowski, A. M., Derewenda, U., Derewenda, Z. S., Dodson, G. G., Lawson, D. M., Turkenburg, J. P., Bjorkling, F., HugeJensen, B., Patkar, S. A., and Thim, L. (1991) Nature 351, 491-494.
3. Derewenda, Z. S., Derewenda, U., and Dodson, G. G. (1992) J. Mol. Biol. 227, 818-839.
4. Derewenda, U., Brzozowski, A. M., Lawson, D. M., and Derewenda Z. S. (1992) Biochemistry 31, 1532-1541.
5. Claesson, P. M., Blomberg, E., Frøberg, J, C., Nylander, T., and Arnebrant, T. (1995) Adv. Colloid Interface Sci. 57, 161-227.
6. Karplus, P. A. (1997) Protein Sci. 6, 1302-1307.
7. Tanford, C. (1997) Protein Sci. 6, 1358-1366.
8. Sussman, F., Villaverde, M. C., and Davis, A. (1997) Protein Sci. 6, 1024-1030.
9. Goddette, D. W., Christianson, T., Ladin, B. F., Lau, M., Mielenz, J. R., Paech, C., Reynolds, R. B., and Wilson, C. R. (1993) J. Biotechnol. 28, 41-54.
10. Dill, K. A. (1997) J. Biol. Chem. 272, 701-704.
11. Piéroni, G., Gargouri, Y., Sarda, L., and Verger, R. (1990) Adv. Colloid Interface Sci. 32, 341-378.
12. Dodson, G. G., Lawson, D. M., and Winkler, F. K. (1992) Faraday Discuss. 93, 95-105.
13. Jain, M. K., Yu, B. Z., and Berg, O. G. (1993) Biochemistry 32, 11319-11329.
14. Thuren T. (1988) FEBS Lett. 229, 95-99.
15. Muderhwa, J. M., and Brockman, H. L. (1992) J. Biol. Chem. 267, 24184-24192.
16. Brockman, H. L. (1984) in Lipases (Bergström, B., and Brockman, H. L., Eds.) pp 1-46, Elsevier Science Publishers, Amsterdam, The Netherlands.
17. Kempner, E. S. (1993) FEBS Lett. 326, 4-10.
18. Philippopoulos, M., Xiang, Y., and Lim, C. (1995) Protein Eng. 8, 565-573.
19. Falzone, C. J., Wright, P. E., and Benkovic, S. J. (1994) Biochemistry 33, 439-442.
20. Williams, J. C., and McDermott, A. E. (1995) Biochemistry 34, 8309-8319.
21. Peters, G. H., Toxvaerd, S., Larsen, N. B., Bjørnholm, T., Schaumburg, K., and Kjaer, K. (1995) Nat. Struct. Biol. 2, 401-409.
22. Peters, G. H., Toxvaerd, S., Olsen, O. H., and Svendsen, A. (1997) Protein Eng. 10, 137-147.
23. Holmquist, M., Martinelle, M., Clausen, I. G., Patkar, S., Svendsen, A., and Huit, K. (1994) Lipids 29, 599-603.
24. Christensen, T., Woeldike, H., Boel, E., Mortensen, A B., Hjortshoej, K., Thim, L., and Hansen, M. T. (1988) Biotechnology 6, 1419-1422.
25. Favazza, M., Lerho, M., and Houssier, C. (1990) J. Biomol. Struct. Dyn. 7, 1291-1300.
26. Nelson, R. M., and Long, G. C. (1989) Anal. Biochem. 180, 147-151.
27. TosoHaas, Montgomeryville, PA.
28. Molecular Probes Europe BV, PoortGebouw, Rijnsburgerweg 10, 2333 AA Leiden, The Netherlands.
29. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
30. Nuclepore, Pleasanton, PA.
31. MacDonald, R. C., MacDonald, R. I., Menco, B. P. M., Takeshita, K., Subbarao, N. K., and Hu, L. (1991) Biochim. Biophys. Acta 1061, 297-303.
32. SLM-Amino Inc., Urbana, IL.
33. Kinnunen, P. K. J., Virtanen, J. A., Tulkki, A. P., Ahuja, R. C., and Möbius, D. (1985) Thin Solid Films 132, 193-203.
34. Murray, R., and Spiegel, R. (1981) in Theory and Problems of Statistics, pp 220-222, Schaum Publ. Company, New York.
35. Lawson, D. M., Brzozowski, A. M., Dodson, G. G., Hubbard, R. E., Huge-Jensen, B., Boel, E., and Derewenda, Z. S. (1994) in Lipases - Their Structure, Biochemistry and Applications (Woolley, P., and Petersen, S. B., Eds.) pp 77-94, Cambridge University Press, Cambridge, U.K.
36. Bernstein, F. C., Koetzle, T. F., Williams, G. J. B., Meyer, E. F., Brice, M. D., Rogers, J. R., Kennard, O., Shimanouchi, T., and Tasumi, M. (1977) J. Mol. Biol. 112, 535-542.
37. Van Gunsteren, W. F., and Berendsen, H. J. C. (1987) GROMOS: Groningen molecular simulation computer program package, University of Groningen, The Netherlands.
38. Berendsen, H. J. C., Postma, J. P. M., van Gunsteren, W. F., and Hermans, J. (1981) in Membrane Proteins: Structures. Interactions and Models (A. Pullman et al., Eds.) pp 457-470, Kluwer Academic Publishers, Leiden University, The Netherlands.
39. Fox, T., and Kollman, P. A. (1996) Proteins: Struct., Funct., Genet. 25, 315-334.
40. Oberoi, H., Trikha, J., Yuan, X., and Allewell, N. M. (1996) Proteins: Struct., Funct., Genet. 25, 300-314.
41. Gilson, M. K. (1995) Curr. Opin. Struct. Biol. 5, 216-223.
42. Van Aalten, D. M. F., Conn, D. A., de Groot, B. L., Berendsen, H. J. C., Findlay, J. B. C., and Amadei, A. (1997) Biophys. J. 73, 2891-2896.
43. Ryckaert, J. P., Ciccotti, G., and Berendsen, H. J. C. (1977) J. Comput. Phys. 23, 327-341.
44. Allen, M. P., and Tildesley, D. J. (1989) in Computer simulation of liquids, Clarendon, Oxford, U.K.
45. Vriend, G. (1990) J. Mol. Graphics 8, 52-56.
46. Amadei, A., Linssen, A. B. M., and Berendsen, H. J. C. (1993) Proteins: Struct., Funct., Genet. 17, 412-425.
47. Ichiye, T., and Karplus, M. (1991) Proteins: Struct., Funct., Genet. 11, 205-217.
48. Balsera, M. A., Wriggers, W., Oono, Y., and Schulten, K. (1996) J. Phys. Chem. 100, 2567-2572.
49. Elamrani, S., Berry, M. B., Phillips, G. N., Jr., and McCammon J. A. (1996) Proteins: Struct., Funct., Genet. 25, 79-88.
50. Marques, O., and Sanejouand, Y.-H. (1995) Proteins: Struct., Funct., Genet. 23, 557-560.
51. Garcia, A. E. (1992) Phys. Rev. Lett. 68, 2696-2699.
52. Subbiah, S. (1996) in Protein Motions Molecular Biology Intelligence Unit, Springer-Verlag, Heidelberg, Germany.
53. Janezic, D., Venable, M., and Brooks, B. R. (1995) J. Comput. Chem. 16, 1554-1566.
54. De Groot, B. L., Amadei, A., Scheek, R. M., van Nuland, N. A. J., and Berendsen, H. J. C. (1996) Proteins: Struct., Funct., Genet. 26, 314-322.
55. Van Aalten, D. M. F., Amadei, A., Linssen, A. B. M., Eijsink, V. G. H., and Vriend, G. (1995) Proteins: Struct., Funct., Genet. 22, 45-54.
56. Kinnunen, P. K. J., Kõiv, A., and Mustonen, P. (1993) in Fluorescence Spectroscopy (Wolfbeis, O. S., Ed.) pp 159-171, Springer-Verlag, New York.
57. Mustonen, P., Lehtonen, J., Kõiv, A., and Kinnunen, P. K. J. (1993) Biochemistry 32, 5373-5380.
58. Kõiv, A., Palvimo, J., and Kinnunen, P. K. J. (1995) Biochemistry 34, 8018-8027.
59. Roberts, G. A., and Tombs, M. P. (1987) Biochim. Biophys. Acta 902, 327-334.
60. Rytömaa, M., and Kinnunen, P. K. J. (1996) Biochemistry 35, 4529-4539.
61. Kinnunen, P. K. J. (1996) Chem. Phys. Lipids 81, 151-166.
62. Möhwald H. (1995) in Structure and Dynamics of Membranes (Lipowsky, R., and Sackmann, E., Eds.) pp 161-211, Elsevier, New York.
63. Mustonen, P., Virtanen, J. A., Somerharju, P. J., and Kinnunen, P. K. J. (1987) Biochemistry 26, 2991-2997.
64. Vainio, P., Virtanen, J. A., and Kinnunen, P. K. J. (1982) Biochim. Biophys. Acta 711, 386-390.
65. Kinnunen, P. K. J., Virtanen, J. A., and Vainio, P. (1983) Atheroscler. Rev. 11, 65-105.
66. Clarage, J. B., Romo, T., Andrews, B. K., Pettitt, B. M., and Phillips, G. N., Jr. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 3288-3292.
67. Hayward, S., Kitao, A., and Berendsen, H. J. C. (1997) Proteins: Struct., Funct., Genet. 27, 425-437.
68. Peters, G. H., van Aalten, D. M. F., Edholm, O., Toxvaerd, S., and Bywater, R. (1996a) Biophys. J. 71, 2245-2255.
69. Peters, G. H., van Aalten, D. M. F., Svendsen, A., and Bywater, R. (1997) Protein Eng. 10, 149-158.
70. Derewenda, U., Swenson, L., Green, R., Wei, Y., Dodson, G. G., Yamaguchi, S., Haas, M. J., and Derewenda, Z. S. (1994) Nat. Struct. Biol. 1, 36-47.
71. Millar, D. P. (1996) Curr. Opin. Struct. Biol. 6, 322-326.
72. Derewenda, Z. S. (1994) Adv. Protein Chem. 45, 1-52.
73. Wade, R. C., Davis, M. E., Luty, B. A., Madura, J. D., and McCammon, J. A. (1993) Biophys. J. 64, 9-15.
74. Wade, R. C., Luty, B. A., Demchuk, E., Madura, J. D., Davies, M. E., Briggs, J. M., and McCammon, J. A. (1994) Nat. Struct. Biol. 1, 63-67.
75. Peters, G. H., Olsen, O. H., Svendsen, A., and Wade, R. C. (1996) Biophys. J. 71, 119-129.
76. Wade, R. C., and McCammon, J. A. (1992) J. Mol. Biol. 225, 679-696.
77. Zhang, Z.-Y., and Wu, L. (1997) Biochemistry 36, 1362-1369.
78. Kabsch, W., and Sander, C. (1983) Biopolymers 22, 2577-2637.