Activation of bacterial thermo alkalophilic lipases is spurred by dramatic structural rearrangements

Journal of Biological Chemistry

Volumn 284, Issue 7, 2009, Pages 4365-4372

  Carrasco López, César ^a   Godoy, César ^b   de las Rivas, Blanca ^b   Fernández Lorente, Gloria ^c   Palomo, José M ^b   Guisán, José M ^b   Fernández Lafuente, Roberto ^b   Martínez Ripoll, Martín ^a   Hermoso, Juan A ^a  

^a INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

^b INSTITUTO DE CATÁLISIS Y PETROLEOQUÍMICA   (Spain)

^c INSTITUTO DE FERMENTACIONES INDUSTRIALES CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ALKALOPHILIC; BINDING DOMAIN; BIOCHEMICAL STUDIES; DETERGENT MOLECULES; ENZYME ACTIVATION; HYDROPHOBIC RESIDUES; N-TERMINAL; OXYANION HOLE; RESTRUCTURING PROCESS; SATURATED FATTY ACID; SHORT SIDE CHAINS; STRUCTURAL CHANGE; STRUCTURAL REARRANGEMENT;

AMINES; AMINO ACIDS; BACTERIOLOGY; CRYSTAL STRUCTURE; FATTY ACIDS; ORGANIC ACIDS; ZINC;

LIPASES;

TRIACYLGLYCEROL LIPASE; ZINC ION; BACTERIAL PROTEIN; FATTY ACID; ZINC;

ALPHA HELIX; AMINO ACID COMPOSITION; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; GEOBACILLUS; GEOBACILLUS THERMOCATENULATUS; HIGH TEMPERATURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; BACILLACEAE; BINDING SITE; CHEMISTRY; ENZYMOLOGY; HEAT; HYDROPHOBICITY; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); GEOBACILLUS THERMOCATENULATUS;

BACILLACEAE; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; FATTY ACIDS; HOT TEMPERATURE; HYDROPHOBICITY; LIPASE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; ZINC;

EID: 63249099729     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808268200     Document Type: Article

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