Influence of lid conformation on lipase enantioselectivity

Journal of Molecular Catalysis - B Enzymatic

Volumn 10, Issue 4, 2000, Pages 385-393

  Overbeeke, P L A ^a   Govardhan, C ^b   Khalaf, N ^b   Jongejan, J A ^a   Heijnen, J J ^a  

^a Kluyver Centre for Genomics of Industrial Fermentation   (Netherlands)

^b Altus Pharmaceuticals Inc   (United States)

Author keywords

CLEC; Enantioselectivity; Free energy diagram; Lid conformation; Lipase

Indexed keywords

CATALYSIS; CATALYST ACTIVITY; CATALYST SELECTIVITY; CONFORMATIONS; ESTERS; FREE ENERGY; FUNGI; HYDROLYSIS; MATHEMATICAL MODELS; PHASE DIAGRAMS; SOLUBILITY;

ENANTIOSELECTIVITY; MICHAELIS-MENTEN COMPLEX; PORCINE PANCREATIC LIPASE;

ENZYMES;

ESTER; FUNGAL ENZYME; GLYCIDYL BUTYRATE; IBUPROFEN DERIVATIVE; IBUPROFEN METHYL ESTER; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA RUGOSA; CONTROLLED STUDY; ENANTIOMER; ENERGY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME SUBSTRATE; HYDROLYSIS; HYPOTHESIS; MICHAELIS MENTEN KINETICS; RACEMIC MIXTURE; STEREOCHEMISTRY;

EID: 0034684070     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1381-1177(99)00110-1     Document Type: Article

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