Optimization of processing parameters for the preparation of phytosterol microemulsions by the solvent displacement method

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 18, 2009, Pages 8426-8433

  Leong, Wai Fun ^a   Che Man, Yaakob B ^a   Lai, Oi Ming ^b   Long, Kamariah ^c   Misran, Misni ^d   Tan, Chin Ping ^a  

^a Faculty of Food Science and Technology   (Malaysia)

^b UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^c MALAYSIAN AGRICULTURAL RESEARCH AND DEVELOPMENT INSTITUTE MARDI   (Malaysia)

^d UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

High pressure homogenization; Microemulsions; Phytosterols; Response surface methodology; Solvent displacement method

Indexed keywords

PHYTOSTEROL; SOLVENT; WATER;

ARTICLE; CHEMISTRY; EMULSION; FOOD INDUSTRY; METHODOLOGY; PARTICLE SIZE; SOLUBILITY; SYNTHESIS;

EMULSIONS; FOOD INDUSTRY; PARTICLE SIZE; PHYTOSTEROLS; SOLUBILITY; SOLVENTS; WATER;

EID: 70349329531     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf901853y     Document Type: Article

References (38)

1. Moghadasian, M. H. Pharmacological properties of plant sterols in vivo and in vitro observations. Life Sci. 2000, 67, 605-615. (Pubitemid 30451899)
2. Noakes, M.; Clifton, P.; Ntanios, F.; Shrapnel, W.; Record, I.; Mclnerney, J. An increase in dietary carotenoids when consuming plant sterols or stanols is effective in maintaining plasma carotenoid concentrations. Am. J. Clin. Nutr. 2002, 75, 79-86.
3. de Jong, A.; Plat, J.; Mensink, R. P. Metabolic effects of plant sterols and stanols. J. Nutr. Biochem. 2003,14, 362-369.
4. Clifton, P. M.; Noakes, M.; Ross, D.; Fassoulakis, A.; Cehun, M.; Nestel, P. High dietary intake of phytosterols esters decreases carotenoids and increases plasma plant sterol levels with no additional cholesterol lowering. J. Lipid Res. 2004, 45,1493-1499. (Pubitemid 39006977)
5. Lichtenstein,A.H.;Deckelbaum,R.J.Stanol/sterolester- containingfoodsandbloodcholesterollevels. AstatementforhealthcareprofessionalsfromtheNutritionCommitteeoftheCouncilon Nutrition,PhysicalActivity,andMetabolismoftheAmericanHeartAssociation. Circulation2001,103,1177-1179.(Pubitemid32200197)
6. Ostlund, R. E. J.; Spilburg, C. A.; Stenson, W. F. Sitostanol administered in lecithin micelles potently reduces cholesterol absorption in humans. Am. J. Clin. Nutr. 1999, 70, 826-831.
7. Gremaud, G.; Dalan, E.; Piguet, C.; Baumgartner, M.; Ballabeni, P.; Decarli, B.; Leser, M. E.; Berger, A.; Fay, L. B. Effects of nonesterified stanols in a liquid emulsion on cholesterol absorption and synthesis in hypercholesterolemic men. Eur. J. Nutr. 2002, 41, 54-60.
8. Engel, R.; Schubert, H. Formulation of phytosterols in emulsions for increased dose response in functional foods. Innovative Food Sci. Emerging Technol. 2005, 6, 233-237.
9. Spernath, A.; Yaghmur, A.; Hoffman, R. E.; Garti, N. Self-diffusion nuclear magnetic resonance, microstructure, transititons, and solubilization capacity of phytosterols and cholesterol in Winsor IV food-grade microemulsions. J. Agric. Food Chem. 2003, 51, 2359-2364.
10. Rozner, S.; Verkhovski, L.; Nissimov, Y.; Aserin, A.; Vilensky, R.; Dañino, D.; Zouboulis, C. C.; Milner, Y.; Garti, N. Inhibition of cholesterol transport into skin cells in cultures by phytosterolsloaded microemulsion. Chem. Phys. Lipids 2008, 153, 109-118.
11. Takeshita, M.; Saito, S.; Katsuragi, Y.; Yasunaga, K.; Matsuo, N.; Tokimitsu, I.; Yasukawa, T.; Nakamura, H. Combination of plant sterols and diacylglycerol oil lowers serum cholesterol and lipoprotein (a) concentrations in postmenopausal women with mild-tomoderate hypercholesterolemia. Clin. Nutr. 2007, 2, 4-11.
12. Trotta, M.; Debernardi, F.; Caputo, O. Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique. Int. J. Pharm. 2003, 257, 153-160. (Pubitemid 36507041)
13. Tan, C. P.; Nakajima, M. β-Carotene nanodispersions: preparation, characterization and stability evaluation. Food Chem. 2005, 92, 661-671. (Pubitemid 40544811)
14. Yuan, Y.; Gao, Y.; Mao, L.; Zhao, J. Optimisation of conditions for the preparation of β-carotene nanoemulsions using response surface methodology. Food Chem. 2008, 107, 1300-1306. (Pubitemid 350161203)
15. Tan, C. P.; Nakajima, M. Effect of polyglycerol esters of fatty acids on physicochemical properties and stability of β-carotene nanodispersions prepared by emulsification/evaporation method. J. Sci. Food Agric 2005, 85, 121-126.
16. Galindo-Rodriguez, S.; Allemann, E.; Fessi, H.; Doelker, E. Physicochemical parameters associated with nanoparticle formation in the salting-out, emulsification-diffusion, and nanoprecipitation methods. Pharm. Res. 2004, 21, 1428-1439. (Pubitemid 39149658)
17. Fessi, H.; Puisieux, F.; Devissaguet, J. P.; Ammoury, N.; Benita, S. Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int. J. Pharm. 1989, 55, R1-R4. (Pubitemid 19247505)
18. Mosqueira, V. C.; Legrand, P.; Pinto-Alphandary, H.; Puisieux, F.; Barratt, G. Poly(D,L-lactide) nanocapsules prepared by a solvent displacement process: influence of the composition on physicochemical and structural properties. J. Pharm. Sci. 2000, 89, 614-626.
19. Teixeira, M.; Alonso, M. J.; Pinto, M. M. M.; Barbosa, C. M. Development and characterization of PLGA nanospheres and nanocapsules containing xanthone and 3-methoxyxanthone. Eur. J. Pharm. Biopharm. 2005, 59, 491-500. (Pubitemid 40347293)
20. Molpeceres, J.; Guzman, M.; Aberturas, M. R.; Chacon, M.; Berges, L. Application of central composite designs to the preparation of polycaprolactone nanoparticles by solvent displacement. J. Pharm. Sci. 1996, 55, 206-213. (Pubitemid 26055803)
21. Alvarez-Roman, R.; Barré, G.; Guy, R. H.; Fessi, H. Biodegradable polymer nanocapsules containing a sunscreen agent: preparation and photoprotection. Eur. J. Pharm. Biopharm. 2001, 52, 191-195. (Pubitemid 32755898)
22. Chu, B. S.; Ichikawa, S.; Kanafusa, S.; Nakajima, M. Preparation of protein-stabilized β-Carotene nanodispersions by emulsification-evaporation method. J. Am. Oil Chem. Soc. 2007, 84, 10531062. (Pubitemid 350023548)
23. Chu, B. S.; Ichikawa, S.; Kanafusa, S.; Nakajima, M. Preparation and characterization of beta-carotene nanodispersions prepared by solvent displacement technique. J. Agric. Food Chem. 2007, 55, 6754-6760.
24. Ribeiro, H. S.; Chu, B. S.; Ichikawa, S.; Nakajima, M. Preparation of nanodispersions containing β-carotene by solvent displacement method. Food Hydrocolloids 2008, 22, 12-17. (Pubitemid 47002056)
25. Yin, L. J.; Chu, B. S.; Kobayashi, I.; Nakajima, M. Performance of selected emulsifiers and their combinations in the preparation of /3-carotene nanodispersions. Food Hydrocolloids 2008, 23, 1617-1622.
26. Jelen, H. H.; Wlazly, K.; Wasowicz, E.; Kaminski, E. Solid-phase microextraction for the analysis of some alcohols and esters in beer: comparison with static headspace method. J. Agric. Food Chem. 1998, 46, 1469-1473.
27. Pinho, O.; Ferreira, I. M. P. L. V. O.; Santos, L. H. M. L. M. Method optimization by solid-phase microextraction in combination with gas chromatography with mass spectrometry for analysis of beer volatile fraction. J. Chromatogr., A 2006, 1121, 145-153. (Pubitemid 44202460)
28. Lee, X. P.; Kumazawa, T.; Sato, K.; Seno, H.; Ishii, A.; Suzuki, O. Improved extraction of ethanol from human body fluids by headspace solid-phase microextraction with a carboxen-polydimethylsiloxane-coated fiber. Chromatographia 1998, 47, 593-595. (Pubitemid 28247426)
29. De Martinis, B. S.; Martins Ruzzene, M. A.; Santos Martin, C C Determination of ethanol in human blood and urine by automated headspace solid-phase microextraction and capillary gas chromatography. Anal. Chim. Acta 2004, 522, 163-168. (Pubitemid 39179972)
30. Bas, D.; Boyad, i.H. Modeling and optimization I: usability of response surface methodology. J. Food Eng. 2007, 78, 836-845.
31. McClements, D. J. Food Emulsion: Principles, Practices and Techniques; CRC Press: London, U.K., 2005;
32. Lo, S. K.; Cheong, N. Z.; Arifin, N.; Tan, C P.; Long, K.; Yusoff, M. S.; Lai, O. M. Diacylglycerol and triacylglycerol as responses in a dual response surface-optimized process for diacylglycerol production by lipase-catalyzed esterification in a pilot packed-bed enzyme reactor. J. Agric Food Chem. 2007, 55, 5595-5603.
33. Solans, C.; Izquierdo, P.; Nolla, J.; Azemar, N.; Garcia-Celma, M. J. Nano-emulsions. Curr. Opin. Colloid Interface Sci. 2005, 10, 102-110.
34. Jafari, S. M.; He, Y.; Bhandari, B. Optimization of nano-emulsions production by microfluidization. Eur. Food Res. Technol. 2007, 225, 733-741.
35. Dickinson, E. An Introduction to Food Colloids; Oxford University Press: Oxford, U.K., 1992; Vol. 1.
36. Taylor, P. Ostwald ripening in emulsions. Adv. Colloid Interface Sci. 1998, 75, 107-163.
37. Riaz, M. N. Chaudry, M. M. Halal Food Production; CRC Press: Boca Raton, FL, 2004.
38. Dickinson, E.; Golding, M. Influence of alcohol on stability of oilin-water emulsions containing sodium caseinate. J. Colloid Interface Sci. 1998,197, 133-141. (Pubitemid 28383542)