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Volumn 102, Issue 3, 2009, Pages 1430-1442

Simulation in sensory neurons reveals a key role for delayed Na+ current in subthreshold oscillations and ectopic discharge: Implications for neuropathic pain

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Indexed keywords

SODIUM ION;

EID: 70349301419     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00005.2009     Document Type: Article
Times cited : (55)

References (76)
  • 1
    • 0036850088 scopus 로고    scopus 로고
    • + channel currents of rat dorsal root ganglion neurons following axotomy and axotomy-induced autotomy
    • + channel currents of rat dorsal root ganglion neurons following axotomy and axotomy-induced autotomy. J Neurophysiol 88: 2518-2529, 2002.
    • (2002) J Neurophysiol , vol.88 , pp. 2518-2529
    • Abdulla, F.A.1    Smith, P.A.2
  • 2
    • 0035793013 scopus 로고    scopus 로고
    • Persistent sodium channel activity mediates subthreshold membrane potential oscillations and low-threshold spikes in rat entorhinal cortex layer V neurons
    • DOI 10.1016/S0306-4522(00)00455-3, PII S0306452200004553
    • Agrawal N, Hamam BN, Magistretti J, Alonso A, Ragsdale DS. Persistent sodium channel activity mediates subthreshold membrane potential oscillations and low-threshold spikes in rat entorhinal cortex layer V neurons. Neuroscience 102: 53-64, 2001. (Pubitemid 32171853)
    • (2001) Neuroscience , vol.102 , Issue.1 , pp. 53-64
    • Agrawal, N.1    Hamam, B.N.2    Magistretti, J.3    Alonso, A.4    Ragsdale, D.S.5
  • 4
    • 0030971318 scopus 로고    scopus 로고
    • Spike-evoked suppression and burst patterning in dorsal root ganglion neurons of the rat
    • DOI 10.1111/j.1469-7793.1997.183bo.x
    • Amir R, Devor M. Spike-evoked suppression and burst patterning in dorsal root ganglion neurons. J Physiol 501: 183-196, 1997. (Pubitemid 27230410)
    • (1997) Journal of Physiology , vol.501 , Issue.1 , pp. 183-196
    • Amir, R.1    Devor, M.2
  • 5
    • 0036158792 scopus 로고    scopus 로고
    • Oscillatory mechanism in primary sensory neurones
    • Amir R, Liu C-N, Kocsis JD, Devor M. Oscillatory mechanism in primary sensory neurons. Brain 125: 421-435, 2002a. (Pubitemid 34127443)
    • (2002) Brain , vol.125 , Issue.2 , pp. 421-435
    • Amir, R.1    Liu, C.-N.2    Kocsis, J.D.3    Devor, M.4
  • 6
    • 0033215996 scopus 로고    scopus 로고
    • Membrane potential oscillations in dorsal root ganglion neurons: Role in normal electrogenesis and neuropathic pain
    • Amir R, Michaelis M, Devor M. Membrane potential oscillations in dorsal root ganglion neurons: role in normal electrogenesis and in neuropathic pain. J Neurosci 19: 8589-8596, 1999. (Pubitemid 30226776)
    • (1999) Journal of Neuroscience , vol.19 , Issue.19 , pp. 8589-8596
    • Amir, R.1    Michaelis, M.2    Devor, M.3
  • 7
    • 0036470142 scopus 로고    scopus 로고
    • Burst discharge in primary sensory neurons: Triggered by subthreshold oscillations, maintained by depolarizing afterpotentials
    • Amir R, Michaelis M, Devor M. Burst discharge in primary sensory neurons: triggered by subthreshold oscillations, maintained by depolarizing afterpotentials. J Neurosci 22: 1187-1198, 2002b. (Pubitemid 34141799)
    • (2002) Journal of Neuroscience , vol.22 , Issue.3 , pp. 1187-1198
    • Amir, R.1    Michaelis, M.2    Devor, M.3
  • 8
    • 0030909407 scopus 로고    scopus 로고
    • Low-threshold, persistent sodium current in rat large dorsal root ganglion neurons in culture
    • Baker M, Bostock H. Low-threshold, persistent sodium current in rat large dorsal root ganglion neurons in culture. J Neurophysiol 77: 1503-1513, 1997. (Pubitemid 27137043)
    • (1997) Journal of Neurophysiology , vol.77 , Issue.3 , pp. 1503-1513
    • Baker, M.D.1    Bostock, H.2
  • 9
    • 0033994954 scopus 로고    scopus 로고
    • + current by local anaesthetics in rat large sensory neurones
    • + current by local anaesthetics in rat large sensory neurones. Br J Pharmacol 129: 1617-1626, 2000.
    • (2000) Br J Pharmacol , vol.129 , pp. 1617-1626
    • Baker, M.D.1
  • 11
    • 0036133937 scopus 로고    scopus 로고
    • Modulation of sodium channels in primary afferent neurons
    • Bevan S, Storey N. Modulation of sodium channels in primary afferent neurons. Novartis Found Symp 241: 144-153, 2002.
    • (2002) Novartis Found Symp , vol.241 , pp. 144-153
    • Bevan, S.1    Storey, N.2
  • 12
    • 0035260258 scopus 로고    scopus 로고
    • Neurotrophic factors and neuropathic pain
    • Boucher TJ, McMahon SB. Neurotrophic factors and neuropathic pain. Curr Opin Pharmacol 1: 66-72, 2001.
    • (2001) Curr Opin Pharmacol , vol.1 , pp. 66-72
    • Boucher, T.J.1    McMahon, S.B.2
  • 13
    • 0026727782 scopus 로고
    • Three types of sodium channels in adult rat dorsal root ganglion neurons
    • Caffrey JM, Eng DL, Black JA, Waxman SG, Kocsis JD. Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Res 592: 283-297, 1992.
    • (1992) Brain Res , vol.592 , pp. 283-297
    • Caffrey, J.M.1    Eng, D.L.2    Black, J.A.3    Waxman, S.G.4    Kocsis, J.D.5
  • 14
    • 0023924048 scopus 로고
    • Myelinated afferents signal the hyperalgesia associated with nerve injury
    • Campbell JN, Raja SN, Meyer RA, MacKinnon SE. Myelinated afferents signal the hyperalgesia associated with nerve injury. Pain 32: 89-94, 1988.
    • (1988) Pain , vol.32 , pp. 89-94
    • Campbell, J.N.1    Raja, S.N.2    Meyer, R.A.3    MacKinnon, S.E.4
  • 15
    • 0034523226 scopus 로고    scopus 로고
    • Cloning, distribution and functional analysis of the type III sodium channel from human brain
    • Chen YH, Dale TJ, Romanos MA, Whitaker WR, Xie XM, Clare JJ. Cloning, distribution and functional analysis of the type III sodium channel from human brain. Eur J Neurosci 12: 4281-4289, 2000.
    • (2000) Eur J Neurosci , vol.12 , pp. 4281-4289
    • Chen, Y.H.1    Dale, T.J.2    Romanos, M.A.3    Whitaker, W.R.4    Xie, X.M.5    Clare, J.J.6
  • 17
    • 0029932350 scopus 로고    scopus 로고
    • Persistent sodium current in mammalian central neurons
    • Crill WE. Persistent sodium current in mammalian central neurons. Annu Rev Physiol 58: 349-362, 1996. (Pubitemid 26106725)
    • (1996) Annual Review of Physiology , vol.58 , pp. 349-362
    • Crill, W.E.1
  • 18
    • 0033572137 scopus 로고    scopus 로고
    • A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons
    • Cummins TR, Dib-Hajj SD, Black JA, Akopian AN, Wood JN, Waxman SG. A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. J Neurosci 19: RC43, 1999.
    • (1999) J Neurosci , vol.19
    • Cummins, T.R.1    Dib-Hajj, S.D.2    Black, J.A.3    Akopian, A.N.4    Wood, J.N.5    Waxman, S.G.6
  • 19
    • 4644268452 scopus 로고    scopus 로고
    • Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy
    • Cummins TR, Dib-Hajj SD, Waxman SG. Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy. J Neurosci 24: 8232-8236, 2004.
    • (2004) J Neurosci , vol.24 , pp. 8232-8236
    • Cummins, T.R.1    Dib-Hajj, S.D.2    Waxman, S.G.3
  • 20
    • 0002529104 scopus 로고
    • The pathophysiology of damaged peripheral nerve
    • edited by Wall PD, Melzack R. London: Churchill Livingston
    • Devor M. The pathophysiology of damaged peripheral nerve. In: Textbook of Pain (2nd ed.), edited by Wall PD, Melzack R. London: Churchill Livingston, 1989, p. 63-81.
    • (1989) Textbook of Pain (2nd Ed.) , pp. 63-81
    • Devor, M.1
  • 21
    • 30844438395 scopus 로고    scopus 로고
    • Response of nerves to injury in relation to neuropathic pain
    • edited by McMahon SL, Koltzenburg M. London: Churchill Livingstone
    • Devor M. Response of nerves to injury in relation to neuropathic pain. In: Wall and Melzack's Textbook of Pain (5th ed.), edited by McMahon SL, Koltzenburg M. London: Churchill Livingstone, 2006, p. 905-927.
    • (2006) Wall and Melzack's Textbook of Pain (5th Ed.) , pp. 905-927
    • Devor, M.1
  • 22
    • 67349270225 scopus 로고    scopus 로고
    • Ectopic discharge in A-beta afferents as a source of neuropathic pain
    • Devor M. Ectopic discharge in A-beta afferents as a source of neuropathic pain. Exp Brain Res 196: 115-128, 2009a.
    • (2009) Exp Brain Res , vol.196 , pp. 115-128
    • Devor, M.1
  • 23
    • 69049110850 scopus 로고    scopus 로고
    • How does gabapentin relieve neuropathic pain?
    • June 18, doi:10.1016/j.pain.2009.05.030
    • Devor M. How does gabapentin relieve neuropathic pain? Pain (June 18, 2009b). doi:10.1016/j.pain.2009.05.030.
    • (2009) Pain
    • Devor, M.1
  • 24
    • 0016812396 scopus 로고
    • Late sodium current in the node of Ranvier
    • Dubois JM, Bergman C. Late sodium current in the node of Ranvier. Pflügers Arch 357: 145-148, 1975.
    • (1975) Pflügers Arch , vol.357 , pp. 145-148
    • Dubois, J.M.1    Bergman, C.2
  • 25
    • 0030933489 scopus 로고    scopus 로고
    • + channel inactivation and bursting discharge in a simple model axon: Implications for neuropathic pain
    • DOI 10.1016/S0006-8993(97)00072-3, PII S0006899397000723
    • Elliott J. Slow Na+ channel inactivation and bursting discharge in a simple model axon: implications for neuropathic pain. Brain Res 754: 221-226, 1997. (Pubitemid 27170271)
    • (1997) Brain Research , vol.754 , Issue.1-2 , pp. 221-226
    • Elliott, J.R.1
  • 26
    • 33645453621 scopus 로고    scopus 로고
    • Participation of sodium currents in burst generation and control of membrane excitability in mesencephalic trigeminal neurons
    • Enomoto A, Han JM, Hsiao CF, Wu N, Chandler SH. Participation of sodium currents in burst generation and control of membrane excitability in mesencephalic trigeminal neurons. J Neurosci 26: 3412-3422, 2006.
    • (2006) J Neurosci , vol.26 , pp. 3412-3422
    • Enomoto, A.1    Han, J.M.2    Hsiao, C.F.3    Wu, N.4    Chandler, S.H.5
  • 27
    • 0031945498 scopus 로고    scopus 로고
    • Morphologically identified cutaneous afferent DRG neurons express three different potassium currents in varying proportions
    • Everill B, Rizzo MA, Kocsis JD. Morphologically identified cutaneous afferent DRG neurons express three different potassium currents in varying proportions. J Neurophysiol 79: 1814-1824, 1998.
    • (1998) J Neurophysiol , vol.79 , pp. 1814-1824
    • Everill, B.1    Rizzo, M.A.2    Kocsis, J.D.3
  • 28
    • 0032495860 scopus 로고    scopus 로고
    • Voltage-operated potassium currents in the somatic membrane of rat dorsal root ganglion neurons: Ontogenetic aspects
    • Fedulova SA, Vasilyev DA, Veselovsky NS. Voltage-operated potassium currents in the somatic membrane of rat dorsal root ganglion neurons: ontogenetic aspects. Neuroscience 85: 497-508, 1998.
    • (1998) Neuroscience , vol.85 , pp. 497-508
    • Fedulova, S.A.1    Vasilyev, D.A.2    Veselovsky, N.S.3
  • 29
    • 0034633790 scopus 로고    scopus 로고
    • Lack of efficacy of riluzole in the treatment of peripheral neuropathic pain conditions
    • Galer BS, Twilling LL, Harle J, Cluff RS, Friedman E, Rowbotham MC. Lack of efficacy of riluzole in the treatment of peripheral neuropathic pain conditions. Neurology 55: 971-975, 2000. (Pubitemid 30764359)
    • (2000) Neurology , vol.55 , Issue.7 , pp. 971-975
    • Galer, B.S.1    Twilling, L.L.2    Harle, J.3    Cluff, R.S.4    Friedman, E.5    Rowbotham, M.C.6
  • 30
    • 0141646635 scopus 로고    scopus 로고
    • v1.7 sodium channels in mouse spinal sensory neurons
    • DOI 10.1113/jphysiol.2003.047357
    • Herzog RI, Cummins TR, Ghassemi F, Dib-Hajj SD, Waxman SG. Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons. J Physiol 551: 741-750, 2003. (Pubitemid 37221069)
    • (2003) Journal of Physiology , vol.551 , Issue.3 , pp. 741-750
    • Herzog, R.I.1    Cummins, T.R.2    Ghassemi, F.3    Dib-Hajj, S.D.4    Waxman, S.G.5
  • 31
    • 0034843601 scopus 로고    scopus 로고
    • + current affects resting potential and response to depolarization in simulated spinal sensory neurons
    • + current affects resting potential and response to depolarization in simulated spinal sensory neurons. J Neurophysiol 86: 1351-1364, 2001.
    • (2001) J Neurophysiol , vol.86 , pp. 1351-1364
    • Herzog, R.I.1    Cummins, T.R.2    Waxman, S.G.3
  • 32
    • 0031571202 scopus 로고    scopus 로고
    • The NEURON simulation environment
    • Hines ML, Carnevale NT. The NEURON simulation environment. Neural Comput 9: 1179-1209, 1997.
    • (1997) Neural Comput , vol.9 , pp. 1179-1209
    • Hines, M.L.1    Carnevale, N.T.2
  • 33
    • 28444488633 scopus 로고    scopus 로고
    • Altered expression and function of sodium channels in large DRG neurons and myelinated A-fibers in early diabetic neuropathy in the rat
    • DOI 10.1016/j.bbrc.2005.11.057, PII S0006291X05025866
    • Hong S, Wiley JW. Altered expression and function of sodium channels in large DRG neurons and myelinated A-fibers in early diabetic neuropathy in the rat. Biochem Biophys Res Commun 339: 652-660, 2006. (Pubitemid 41739717)
    • (2006) Biochemical and Biophysical Research Communications , vol.339 , Issue.2 , pp. 652-660
    • Hong, S.1    Wiley, J.W.2
  • 34
    • 0030987951 scopus 로고    scopus 로고
    • Slow sodium-dependent potential oscillations contribute to ectopic firing in mammalian demyelinated axons
    • DOI 10.1093/brain/120.4.647
    • Kapoor R, Li Y-G, Smith K. Slow sodium-dependent potential oscillations contribute to ectopic firing in mammalian demyelinated axons. Brain 120: 647-652, 1997. (Pubitemid 27174099)
    • (1997) Brain , vol.120 , Issue.4 , pp. 647-652
    • Kapoor, R.1    Li, Y.-G.2    Smith, K.J.3
  • 36
    • 0028235568 scopus 로고
    • Nociceptor modulated central sensitization causes mechanical hyperalgesia in acute chemogenic and chronic neuropathic pain
    • Koltzenburg M, Torebjork H, Wahren L. Nociceptor modulated central sensitization causes mechanical hyperalgesia in acute chemogenic and chronic neuropathic pain. Brain 117: 579-591, 1994. (Pubitemid 24225905)
    • (1994) Brain , vol.117 , Issue.3 , pp. 579-591
    • Koltzenburg, M.1    Torebjork, H.E.2    Wahren, L.K.3
  • 37
    • 5444232079 scopus 로고    scopus 로고
    • Persistent subthreshold voltage-dependent cation single channels in suprachiasmatic nucleus neurons
    • DOI 10.1016/j.neuroscience.2004.06.080, PII S030645220400661X
    • Kononenko NI, Medina I, Dudek FE. Persistent subthreshold voltage-dependent cation single channels in suprachiasmatic nucleus neurons. Neuroscience 129: 85-92, 2004a. (Pubitemid 39360944)
    • (2004) Neuroscience , vol.129 , Issue.1 , pp. 85-92
    • Kononenko, N.I.1    Medina, I.2    Dudek, F.E.3
  • 38
    • 0842284657 scopus 로고    scopus 로고
    • Riluzole-sensitive slowly inactivating sodium current in rat suprachiasmatic nucleus neurons
    • Kononenko NI, Shao LR, Dudek FE. Riluzole-sensitive slowly inactivating sodium current in rat suprachiasmatic nucleus neurons. J Neurophysiol 91: 710-718, 2004b.
    • (2004) J Neurophysiol , vol.91 , pp. 710-718
    • Kononenko, N.I.1    Shao, L.R.2    Dudek, F.E.3
  • 39
    • 0019825967 scopus 로고
    • Ionic currents in the somatic membrane of rat dorsal root ganglion neurons: I. Sodium currents
    • DOI 10.1016/0306-4522(81)90088-9
    • Kostyuk PG, Veselovsky NS, Tsyndrenko AY. Ionic currents in the somatic membrane of rat dorsal root ganglion neurons. I. Sodium currents. Neuroscience 6: 2423-2430, 1981. (Pubitemid 12247032)
    • (1981) Neuroscience , vol.6 , Issue.12 , pp. 2423-2430
    • Kostyuk, P.G.1    Veselovsky, N.S.2    Tsyndrenko, A.Y.3
  • 40
    • 39249083820 scopus 로고    scopus 로고
    • Subthreshold oscillations facilitate neuropathic spike discharge by overcoming membrane accommodation
    • Kovalsky Y, Amir R, Devor M. Subthreshold oscillations facilitate neuropathic spike discharge by overcoming membrane accommodation. Exp Neurol 210: 194-206, 2008.
    • (2008) Exp Neurol , vol.210 , pp. 194-206
    • Kovalsky, Y.1    Amir, R.2    Devor, M.3
  • 41
    • 33746217759 scopus 로고    scopus 로고
    • Essential role of the persistent sodium current in spike initiation during slowly rising inputs in mouse spinal neurones
    • DOI 10.1113/jphysiol.2006.107094
    • Kuo JJ, Lee RH, Zhang L, Heckman CJ. Essential role of the persistent sodium current in spike initiation during slowly rising inputs in mouse spinal neurones. J Physiol 574: 819-834, 2006. (Pubitemid 44089073)
    • (2006) Journal of Physiology , vol.574 , Issue.3 , pp. 819-834
    • Kuo, J.J.1    Lee, R.H.2    Zhang, L.3    Heckman, C.J.4
  • 42
    • 0034175686 scopus 로고    scopus 로고
    • Tactile allodynia in the absence of C-fiber activation: Altered firing properties of DRG neurons following spinal nerve injury
    • DOI 10.1016/S0304-3959(00)00251-7, PII S0304395900002517
    • Liu C-N, Wall PD, Ben-Dor E, Michaelis M, Amir R, Devor M. Tactile allodynia in the absence of C-fiber activation: altered firing properties of DRG neurons following spinal nerve injury. Pain 8: 503-521, 2000a. (Pubitemid 30214179)
    • (2000) Pain , vol.85 , Issue.3 , pp. 503-521
    • Liu, C.-N.1    Wall, P.D.2    Ben-Dor, E.3    Michaelis, M.4    Amir, R.5    Devor, M.6
  • 43
    • 0033957307 scopus 로고    scopus 로고
    • Spontaneous activity of axotomized afferent neurons after L5 spinal nerve injury in rats
    • DOI 10.1016/S0304-3959(99)00211-0, PII S0304395999002110
    • Liu X, Eschenfelder S, Blenk K-H, Janig W, Habler H-J. Spontaneous activity of axotomized afferent neurons after L5 spinal nerve injury in rats. Pain 8: 4309-4318, 2000b. (Pubitemid 30074233)
    • (2000) Pain , vol.84 , Issue.2-3 , pp. 309-318
    • Liu, X.1    Eschenfelder, S.2    Blenk, K.-H.3    Janig, W.4    Habler, H.-J.5
  • 45
    • 0033983432 scopus 로고    scopus 로고
    • Abnormal substance P release from the spinal cord following injury to primary sensory neurons
    • DOI 10.1046/j.1460-9568.2000.00946.x
    • Malcangio M, Ramer MS, Jones MG, McMahon SB. Abnormal substance P release from the spinal cord following injury to primary sensory neurons. Eur J Neurosci 12: 397-399, 2000. (Pubitemid 30068447)
    • (2000) European Journal of Neuroscience , vol.12 , Issue.1 , pp. 397-399
    • Malcangio, M.1    Ramer, M.S.2    Jones, M.G.3    McMahon, S.B.4
  • 46
    • 16344365831 scopus 로고    scopus 로고
    • Molecular determinants for modulation of persistent sodium current by G-protein βγ subunits
    • DOI 10.1523/JNEUROSCI.0104-05.2005
    • Mantegazza M, Yu FH, Powell AJ, Clare JJ, Catterall WA, Scheuer T. Molecular determinants for modulation of persistent sodium current by G-protein betagamma subunits. J Neurosci 25: 3341-3349, 2005. (Pubitemid 40471342)
    • (2005) Journal of Neuroscience , vol.25 , Issue.13 , pp. 3341-3349
    • Mantegazza, M.1    Yu, F.H.2    Powell, A.J.3    Clare, J.J.4    Catterall, W.A.5    Scheuer, T.6
  • 48
    • 33745392178 scopus 로고    scopus 로고
    • Late sodium current in the pathophysiology of cardiovascular disease: Consequences of sodium-calcium overload
    • DOI 10.1136/hrt.2005.078782
    • Noble D, Noble PJ. Late sodium current in the pathophysiology of cardiovascular disease: consequences of sodium-calcium overload. Heart 92: iv1-iv5, 2006. (Pubitemid 43974035)
    • (2006) Heart , vol.92 , Issue.SUPPL. 4
    • Noble, D.1    Noble, P.J.2
  • 49
    • 0028800179 scopus 로고
    • Substance P induced by peripheral nerve injury in primary afferent sensory neurons and its effect on dorsal column nucleus neurons
    • Noguchi K, Kawai Y, Fukuoka T, Senba E, Miki K. Substance P induced by peripheral nerve injury in primary afferent sensory neurons and its effect on dorsal column nucleus neurons. J Neurosci 15: 7633-7643, 1995.
    • (1995) J Neurosci , vol.15 , pp. 7633-7643
    • Noguchi, K.1    Kawai, Y.2    Fukuoka, T.3    Senba, E.4    Miki, K.5
  • 50
    • 0002345618 scopus 로고
    • Voltage-gated ion channels in dorsal root ganglion neurons
    • edited by Scott SA. New York: Oxford Univ. Press
    • Nowycky MC. Voltage-gated ion channels in dorsal root ganglion neurons. In: Sensory Neurons, edited by Scott SA. New York: Oxford Univ. Press, 1992, p. 97-115.
    • (1992) Sensory Neurons , pp. 97-115
    • Nowycky, M.C.1
  • 51
    • 0037033085 scopus 로고    scopus 로고
    • Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena
    • DOI 10.1074/jbc.M204063200
    • Peng K, Shu Q, Liu Z, Liang S. Function and solution structure of huwentoxin- IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena. J Biol Chem 277: 47564-47571, 2002. (Pubitemid 36159276)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.49 , pp. 47564-47571
    • Peng, K.1    Shu, Q.2    Liu, Z.3    Liang, S.4
  • 52
    • 0030841453 scopus 로고    scopus 로고
    • Cellular mechanisms underlying spontaneous firing in rat suprachiasmatic nucleus: Involvement of a slowly inactivating component of sodium current
    • Pennartz CM, Bierlaagh MA, Geurtsen AM. Cellular mechanisms underlying spontaneous firing in rat suprachiasmatic nucleus: involvement of a slowly inactivating component of sodium current. J Neurophysiol 78: 1811-1825, 1997.
    • (1997) J Neurophysiol , vol.78 , pp. 1811-1825
    • Pennartz, C.M.1    Bierlaagh, M.A.2    Geurtsen, A.M.3
  • 53
    • 0041353437 scopus 로고    scopus 로고
    • Intrinsic spontaneous activity and subthreshold oscillations in neurones of the rat dorsal column nuclei in culture
    • DOI 10.1113/jphysiol.2003.039917
    • Reboreda A, Sanchez E, Romero M, Lamas JA. Intrinsic spontaneous activity and subthreshold oscillations in neurones of the rat dorsal column nuclei in culture. J Physiol 551: 191-205, 2003. (Pubitemid 37062922)
    • (2003) Journal of Physiology , vol.551 , Issue.1 , pp. 191-205
    • Reboreda, A.1    Sanchez, E.2    Romero, M.3    Lamas, J.A.4
  • 54
    • 0033837549 scopus 로고    scopus 로고
    • α-SNS Produces the Slow TTX-Resistant Sodium Current in Large Cutaneous Afferent DRG Neurons
    • Renganathan M, Cummins TR, Hormuzdiar WN, Waxman SG. alpha- SNS produces the slow TTR-resistant sodium current in large cutaneous afferent DRG neurons. J Neurophysiol 84: 710-718, 2000. (Pubitemid 30655595)
    • (2000) Journal of Neurophysiology , vol.84 , Issue.2 , pp. 710-718
    • Renganathan, M.1    Cummins, T.R.2    Hormuzdiar, W.N.3    Waxman, S.G.4
  • 55
    • 0029279185 scopus 로고
    • + currents in cutaneous afferent DRG neurons following axotomy
    • + currents in cutaneous afferent DRG neurons following axotomy. Neurobiol Dis 2: 87-96, 1995.
    • (1995) Neurobiol Dis , vol.2 , pp. 87-96
    • Rizzo, M.1    Kocsis, J.2    Waxman, S.3
  • 56
  • 57
    • 0041974814 scopus 로고    scopus 로고
    • + channel Nav1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice
    • + channel Nav1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice. J Physiol 550: 921-926, 2003.
    • (2003) J Physiol , vol.550 , pp. 921-926
    • Roza, C.1    Laird, J.2    Souslova, V.3    Wood, J.N.4    Cervero, F.5
  • 58
    • 33748419893 scopus 로고    scopus 로고
    • Fast oscillations trigger bursts of action potentials in neocortical neurons in vitro: A quasiwhite-noise analysis study
    • Schindler KA, Goodman PH, Wieser HG, Douglas RJ. Fast oscillations trigger bursts of action potentials in neocortical neurons in vitro: a quasiwhite-noise analysis study. Brain Res 1110: 201-210, 2006.
    • (2006) Brain Res , vol.1110 , pp. 201-210
    • Schindler, K.A.1    Goodman, P.H.2    Wieser, H.G.3    Douglas, R.J.4
  • 59
    • 0028180572 scopus 로고
    • Variation in IH, IIR, and ILEAK between acutely isolated adult rat dorsal root ganglion neurons of different size
    • Scroggs RS, Todorovic SM, Anderson EG, Fox AP. Variation in IH, IR and ILEAK between acutely isolated adult rat dorsal root ganglion neurons of different size. J Neurosci 71: 271-279, 1994. (Pubitemid 2045611)
    • (1994) Journal of Neurophysiology , vol.71 , Issue.1 , pp. 271-279
    • Scroggs, R.S.1    Todorovic, S.M.2    Anderson, E.G.3    Fox, A.P.4
  • 60
    • 7244255887 scopus 로고    scopus 로고
    • v1.3 in native tissues and increases channel density at the cell surface
    • DOI 10.1523/JNEUROSCI.0322-04.2004
    • Shah BS, Rush AM, Liu S, Tyrrell L, Black JA, Dib-Hajj SD, Waxman SG. Contactin associates with sodium channel Nav1.3 in native tissues and increases channel density at the cell surface. J Neurosci 24: 7387-7399, 2004. (Pubitemid 39100707)
    • (2004) Journal of Neuroscience , vol.24 , Issue.33 , pp. 7387-7399
    • Shah, B.S.1    Rush, A.M.2    Liu, S.3    Tyrrell, L.4    Black, J.A.5    Dib-Hajj, S.D.6    Waxman, S.G.7
  • 63
    • 34447580943 scopus 로고    scopus 로고
    • Spike timing of lacunosom-moleculare targeting interneurons and CA3 pyramidal cells during high-frequency network oscillations in vitro
    • DOI 10.1152/jn.00188.2007
    • Spampanato J, Mody I. Spike timing of lacunosom-moleculare targeting interneurons and CA3 pyramidal cells during high-frequency network oscillations in vitro. J Neurophysiol 98: 96-104, 2007. (Pubitemid 47084802)
    • (2007) Journal of Neurophysiology , vol.98 , Issue.1 , pp. 96-104
    • Spampanato, J.1    Mody, I.2
  • 64
    • 34447628931 scopus 로고    scopus 로고
    • Onset of ectopic firing in the Chung model of neuropathic pain coincides with the onset of tactile allodynia
    • edited by Flor H, Kalso E, Dostrovsky JO. Seattle, WA: IASP Press
    • Tal M, Kim J, Back SK, Na HS, Devor M. Onset of ectopic firing in the Chung model of neuropathic pain coincides with the onset of tactile allodynia. In: Proceedings of the 11th World Congress on Pain, edited by Flor H, Kalso E, Dostrovsky JO. Seattle, WA: IASP Press, 2006, p. 119-130.
    • (2006) Proceedings of the 11th World Congress on Pain , pp. 119-130
    • Tal, M.1    Kim, J.2    Back, S.K.3    Na, H.S.4    Devor, M.5
  • 65
    • 0033787252 scopus 로고    scopus 로고
    • Riluzole inhibits the persistent sodium current in mammalian CNS neurons
    • DOI 10.1046/j.1460-9568.2000.00242.x
    • Urbani A, Belluzzi O. Riluzole inhibits the persistent sodium current in mammalian CNS neurons. Eur J Neurosci 12: 3567-3574, 2000. (Pubitemid 30796058)
    • (2000) European Journal of Neuroscience , vol.12 , Issue.10 , pp. 3567-3574
    • Urbani, A.1    Belluzzi, O.2
  • 68
    • 0027933696 scopus 로고
    • Type III sodium channel mRNA is expressed in embryonic but not in adult spinal sensory neurons, and is reexpressed following axotomy
    • Waxman SG, Kocsis JD, Black JA. Type III sodium channel mRNA is expressed in embryonic but not in adult spinal sensory neurons, and is reexpressed following axotomy. J Neurophysiol 72: 466-470, 1994.
    • (1994) J Neurophysiol , vol.72 , pp. 466-470
    • Waxman, S.G.1    Kocsis, J.D.2    Black, J.A.3
  • 69
    • 33744900904 scopus 로고    scopus 로고
    • Time course of substance P expression in dorsal root ganglia following complete spinal nerve transection
    • DOI 10.1002/cne.20981
    • Weissner W, Winterson BJ, Stuart-Tilley A, Devor M, Bove GM. Time course of substance P expression in dorsal root ganglia following complete spinal nerve transection. J Comp Neurol 497: 78-87, 2006. (Pubitemid 43844569)
    • (2006) Journal of Comparative Neurology , vol.497 , Issue.1 , pp. 78-87
    • Weissner, W.1    Winterson, B.J.2    Stuart-Tilley, A.3    Devor, M.4    Bove, G.M.5
  • 70
    • 0034625770 scopus 로고    scopus 로고
    • Neuronal plasticity: Increasing the gain in pain
    • Woolf CJ, Salter MW. Neuronal plasticity: increasing the gain in pain. Science 288: 1765-1769, 2000.
    • (2000) Science , vol.288 , pp. 1765-1769
    • Woolf, C.J.1    Salter, M.W.2
  • 71
    • 17644424970 scopus 로고    scopus 로고
    • Persistent sodium currents in mesencephalic V neurons participate in burst generation and control of membrane excitability
    • DOI 10.1152/jn.00636.2004
    • Wu N, Enomoto A, Tanaka S, Hsiao C-F, Nykamp DQ, Izhikevich E, Chandler S. Persistent sodium currents in mesencephalic V neurons participate in burst generation and control of membrane excitability. J Neurophysiol 93: 2710-2722, 2005. (Pubitemid 40570851)
    • (2005) Journal of Neurophysiology , vol.93 , Issue.5 , pp. 2710-2722
    • Wu, N.1    Enomoto, A.2    Tanaka, S.3    Hsiao, C.-F.4    Nykamp, D.Q.5    Izhikevich, E.6    Chandler, S.H.7
  • 72
    • 0035370163 scopus 로고    scopus 로고
    • Membrane resonance and subthreshold membrane oscillations in mesencephalic V neurons: Participants in burst generation
    • Wu N, Hsiao C-F, Chandler S. Membrane resonance and subthreshold membrane oscillations in mesencephalic V neurons: participants in burst generation. J Neurosci 21: 3729-3739, 2001. (Pubitemid 32466464)
    • (2001) Journal of Neuroscience , vol.21 , Issue.11 , pp. 3729-3739
    • Wu, N.1    Hsiao, C.-F.2    Chandler, S.H.3
  • 73
    • 0035906539 scopus 로고    scopus 로고
    • Subthreshold membrane potential oscillations of type A neurons in injured DRG
    • Xing J-L, Hu S-J, Long K-P. Subthreshold membrane potential oscillations of type A neurons in injured DRG. Brain Res 901: 128-136, 2001.
    • (2001) Brain Res , vol.901 , pp. 128-136
    • Xing, J.-L.1    Hu, S.-J.2    Long, K.-P.3
  • 74
    • 63449122889 scopus 로고    scopus 로고
    • Gabapentin selectively reduces persistent sodium current in injured type-A dorsal root ganglion neurons
    • Yang RH, Wang WT, Chen JY, Xie RG, Hu SJ. Gabapentin selectively reduces persistent sodium current in injured type-A dorsal root ganglion neurons. Pain 143: 48-55, 2009.
    • (2009) Pain , vol.143 , pp. 48-55
    • Yang, R.H.1    Wang, W.T.2    Chen, J.Y.3    Xie, R.G.4    Hu, S.J.5
  • 75
    • 0029884777 scopus 로고    scopus 로고
    • + currents in dorsal root ganglion neurones innervating the rat urinary bladder
    • + currents in dorsal root ganglion neurones innervating the rat urinary bladder. J Physiol 494: 1-16, 1996.
    • (1996) J Physiol , vol.494 , pp. 1-16
    • Yoshimura, N.1    White, G.2    Weight, F.F.3    De Groat, W.C.4


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