메뉴 건너뛰기




Volumn 120, Issue 4, 1997, Pages 647-652

Slow sodium-dependent potential oscillations contribute to ectopic firing in mammalian demyelinated axons

Author keywords

4 aminopyridine; Paraesthesiae; Sodium channels; Spontaneous activity

Indexed keywords

4 AMINOPYRIDINE; POTASSIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN;

EID: 0030987951     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/120.4.647     Document Type: Article
Times cited : (75)

References (23)
  • 1
    • 0026773253 scopus 로고
    • Ectopic activity in demyelinated spinal root axons of the rat
    • Lond
    • Baker M, Bostock H. Ectopic activity in demyelinated spinal root axons of the rat. J Physiol (Lond) 1992; 451: 539-52.
    • (1992) J Physiol , vol.451 , pp. 539-552
    • Baker, M.1    Bostock, H.2
  • 2
    • 1842300687 scopus 로고    scopus 로고
    • Sustained inward currents in large neurones cultured from adult rat dorsal root ganglia
    • Lond
    • Baker M, Bostock H. Sustained inward currents in large neurones cultured from adult rat dorsal root ganglia. J Physiol (Lond) 1996; 491P: 141P-2P.
    • (1996) J Physiol , vol.491 P
    • Baker, M.1    Bostock, H.2
  • 3
    • 0025843586 scopus 로고
    • Distribution of sodium channels in chronically demyelinated spinal cord axons: Immuno-ultrastructural localization and electrophysiological observations
    • Black JA, Felts P, Smith KJ, Kocsis JD, Waxman SG. Distribution of sodium channels in chronically demyelinated spinal cord axons: immuno-ultrastructural localization and electrophysiological observations. Brain Res 1991; 544: 59-70.
    • (1991) Brain Res , vol.544 , pp. 59-70
    • Black, J.A.1    Felts, P.2    Smith, K.J.3    Kocsis, J.D.4    Waxman, S.G.5
  • 4
    • 0027948595 scopus 로고
    • Post-tetanic excitability changes and ectopic discharges in a human motor axon
    • Bostock H, Bergmans J. Post-tetanic excitability changes and ectopic discharges in a human motor axon. Brain 1994; 117: 913-28.
    • (1994) Brain , vol.117 , pp. 913-928
    • Bostock, H.1    Bergmans, J.2
  • 5
    • 1842296571 scopus 로고
    • The time constants of motor and sensory axons in human peripheral nerve
    • Lond
    • Bostock H, Rothwell JC. The time constants of motor and sensory axons in human peripheral nerve. J Physiol (Lond) 1995; 487P: 47P.
    • (1995) J Physiol , vol.487 P
    • Bostock, H.1    Rothwell, J.C.2
  • 6
    • 0025886951 scopus 로고
    • Changes in excitability of human motor axons underlying post-ischaemic fasciculations: Evidence for two stable states
    • Lond
    • Bostock H, Baker M, Reid G. Changes in excitability of human motor axons underlying post-ischaemic fasciculations: evidence for two stable states. J Physiol (Lond) 1991; 441: 537-57.
    • (1991) J Physiol , vol.441 , pp. 537-557
    • Bostock, H.1    Baker, M.2    Reid, G.3
  • 7
    • 0023214855 scopus 로고
    • Physiological effects of 4-aminopyridine on demyelinated mammalian motor and sensory fibers
    • Bowe CM, Kocsis JD, Targ EF, Waxman SG. Physiological effects of 4-aminopyridine on demyelinated mammalian motor and sensory fibers. Ann Neurol 1987; 22: 264-8.
    • (1987) Ann Neurol , vol.22 , pp. 264-268
    • Bowe, C.M.1    Kocsis, J.D.2    Targ, E.F.3    Waxman, S.G.4
  • 8
    • 0019391114 scopus 로고
    • Evidence for the presence of potassium channels in the paranodal region of acutely demyelinated mammalian single nerve fibres
    • Lond
    • Chiu SY, Ritchie JM. Evidence for the presence of potassium channels in the paranodal region of acutely demyelinated mammalian single nerve fibres. J Physiol (Lond) 1981; 313: 415-37.
    • (1981) J Physiol , vol.313 , pp. 415-437
    • Chiu, S.Y.1    Ritchie, J.M.2
  • 9
    • 0027751689 scopus 로고
    • Activation of internodal potassium conductance in rat myelinated axons
    • Lond
    • David G, Barrett JN, Barrett EF. Activation of internodal potassium conductance in rat myelinated axons. J Physiol (Lond) 1993; 472: 177-202.
    • (1993) J Physiol , vol.472 , pp. 177-202
    • David, G.1    Barrett, J.N.2    Barrett, E.F.3
  • 10
    • 0026589860 scopus 로고
    • Conduction properties of central nerve fibers remyelinated by Schwann cells
    • Felts PA, Smith KJ. Conduction properties of central nerve fibers remyelinated by Schwann cells. Brain Res 1992; 574: 178-92.
    • (1992) Brain Res , vol.574 , pp. 178-192
    • Felts, P.A.1    Smith, K.J.2
  • 11
    • 0028826348 scopus 로고
    • A mechanism for ectopic firing in central demyelinated axons
    • Felts PA, Kapoor R, Smith KJ. A mechanism for ectopic firing in central demyelinated axons. Brain 1995; 118: 1225-31.
    • (1995) Brain , vol.118 , pp. 1225-1231
    • Felts, P.A.1    Kapoor, R.2    Smith, K.J.3
  • 12
    • 0015888037 scopus 로고
    • A quantitative analysis of the effects of the intraneural injection of lysophosphatidyl choline
    • Gregson NA, Hall SM. A quantitative analysis of the effects of the intraneural injection of lysophosphatidyl choline. J Cell Sci 1973; 13: 257-77.
    • (1973) J Cell Sci , vol.13 , pp. 257-277
    • Gregson, N.A.1    Hall, S.M.2
  • 13
    • 0015150961 scopus 로고
    • The in vivo and ultrastructural effects of injection of lysophosphatidyl choline into myelinated peripheral nerve fibres of the adult mouse
    • Hall SM, Gregson NA. The in vivo and ultrastructural effects of injection of lysophosphatidyl choline into myelinated peripheral nerve fibres of the adult mouse. J Cell Sci 1971; 9: 769-89.
    • (1971) J Cell Sci , vol.9 , pp. 769-789
    • Hall, S.M.1    Gregson, N.A.2
  • 15
    • 0027153109 scopus 로고
    • Internodal potassium currents can generate ectopic impulses in mammalian myelinated axons
    • Kapoor R, Smith KJ, Felts PA, Davies M. Internodal potassium currents can generate ectopic impulses in mammalian myelinated axons. Brain Res 1993; 611: 165-9.
    • (1993) Brain Res , vol.611 , pp. 165-169
    • Kapoor, R.1    Smith, K.J.2    Felts, P.A.3    Davies, M.4
  • 16
    • 0020505960 scopus 로고
    • Maturation of mammalian myelinated fibers: Changes in action-potential characteristics following 4-aminopyridine application
    • Kocsis JD, Ruiz JA, Waxman SG. Maturation of mammalian myelinated fibers: changes in action-potential characteristics following 4-aminopyridine application. J Neurophysiol 1983; 50: 449-63.
    • (1983) J Neurophysiol , vol.50 , pp. 449-463
    • Kocsis, J.D.1    Ruiz, J.A.2    Waxman, S.G.3
  • 17
    • 0014723429 scopus 로고
    • The effects of experimental demyelination on conduction in the central nervous system
    • McDonald WI, Sears TA. The effects of experimental demyelination on conduction in the central nervous system. Brain 1970; 93: 583-98.
    • (1970) Brain , vol.93 , pp. 583-598
    • McDonald, W.I.1    Sears, T.A.2
  • 18
    • 0018910550 scopus 로고
    • Ephaptic transmission between single nerve fibres in the spinal nerve roots of dystrophic mice
    • Lond
    • Rasminsky M. Ephaptic transmission between single nerve fibres in the spinal nerve roots of dystrophic mice. J Physiol (Lond) 1980; 305: 151-69.
    • (1980) J Physiol , vol.305 , pp. 151-169
    • Rasminsky, M.1
  • 19
    • 0024456476 scopus 로고
    • Heterogeneous distribution of fast and slow potassium channels in myelinated rat nerve fibres
    • Lond
    • Roper J, Schwarz JR. Heterogeneous distribution of fast and slow potassium channels in myelinated rat nerve fibres. J Physiol (Lond) 1989; 416: 93-110.
    • (1989) J Physiol , vol.416 , pp. 93-110
    • Roper, J.1    Schwarz, J.R.2
  • 20
    • 0029055254 scopus 로고
    • Action potentials and membrane currents in the human node of Ranvier
    • Schwarz JR, Reid G, Bostock H. Action potentials and membrane currents in the human node of Ranvier. Pflugers Arch 1995; 430: 283-92.
    • (1995) Pflugers Arch , vol.430 , pp. 283-292
    • Schwarz, J.R.1    Reid, G.2    Bostock, H.3
  • 21
    • 0019135203 scopus 로고
    • Nerve conduction during peripheral demyelination and remyelination
    • Smith KJ, Hall SM. Nerve conduction during peripheral demyelination and remyelination. J Neurol Sci 1980; 48: 201-19.
    • (1980) J Neurol Sci , vol.48 , pp. 201-219
    • Smith, K.J.1    Hall, S.M.2
  • 22
    • 0027185851 scopus 로고
    • Noninactivating, tetrodotoxin-sensitive Na+ conductance in rat optic nerve axons
    • Stys PK, Sontheimer H, Ransom BR, Waxman SG. Noninactivating, tetrodotoxin-sensitive Na+ conductance in rat optic nerve axons. Proc Natl Acad Sci USA 1993; 90: 6976-80.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6976-6980
    • Stys, P.K.1    Sontheimer, H.2    Ransom, B.R.3    Waxman, S.G.4
  • 23
    • 0022652854 scopus 로고
    • Action potential characteristics of demyelinated rat sciatic nerve following application of 4-aminopyridine
    • Targ EF, Kocsis JD. Action potential characteristics of demyelinated rat sciatic nerve following application of 4-aminopyridine. Brain Res 1986; 363: 1-9.
    • (1986) Brain Res , vol.363 , pp. 1-9
    • Targ, E.F.1    Kocsis, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.