Altered expression and function of sodium channels in large DRG neurons and myelinated A-fibers in early diabetic neuropathy in the rat

Biochemical and Biophysical Research Communications

Volumn 339, Issue 2, 2006, Pages 652-660

  Hong, Shuangsong ^a   Wiley, John W ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

A fibers; Diabetes; Dorsal root ganglion; Nav1.9; Nodes of Ranvier; Tetrodotoxin resistant; Tetrodotoxin sensitive; Voltage gated sodium channels

Indexed keywords

SODIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL ACTIVATION; CELL KINETICS; CELL SIZE; CONTROLLED STUDY; DIABETIC NEUROPATHY; ELECTRIC POTENTIAL; IMMUNOFLUORESCENCE; MALE; MOLECULAR BIOLOGY; MYELINATED NERVE; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM CURRENT; SPINAL GANGLION; STAINING; STATISTICAL SIGNIFICANCE;

ANIMALS; CELLS, CULTURED; DIABETIC NEUROPATHIES; ELECTROPHYSIOLOGY; GANGLIA, SPINAL; KINETICS; MALE; MODELS, BIOLOGICAL; NERVE FIBERS, MYELINATED; NERVE FIBERS, UNMYELINATED; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SODIUM CHANNELS; TIME FACTORS;

ANIMALIA;

EID: 28444488633     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.11.057     Document Type: Article

References (36)

1. A.J. Boulton, and R.A. Malik Diabetic neuropathy Med. Clin. North Am. 82 1998 909 929
2. S.N. Lawson Phenotype and function of somatic primary afferent nociceptive neurones with C-, Adelta- or Aalpha/beta-fibres Exp. Physiol 87 2002 239 244
3. X. Chen, and J.D. Levine Hyper-responsivity in a subset of C-fiber nociceptors in a model of painful diabetic neuropathy in the rat Neuroscience 102 2001 185 192
4. S.C. Ahlgren, and J.D. Levine Mechanical hyperalgesia in streptozotocin-diabetic rats is not sympathetically maintained Brain Res. 616 1993 171 175
5. G.M. Khan, S.R. Chen, and H.L. Pan Role of primary afferent nerves in allodynia caused by diabetic neuropathy in rats Neuroscience 114 2002 291 299
6. E. Ochodnicka, M. Ochdnicky, K. Belej, E. Fusekova, and L. Bosel'ova Quantitative analysis of myelinated nerve fibers of peripheral nerve in streptozotocin-induced diabetes mellitus Mol. Chem. Neuropathol. 25 1995 225 233
7. A.P. Mizisin, G.D. Shelton, S. Wagner, C. Rusbridge, and H.C. Powell Myelin splitting, Schwann cell injury and demyelination in feline diabetic neuropathy Acta. Neuropathol. (Berl.) 95 1998 171 174
8. L.J. Hudson, S. Bevan, K. McNair, C. Gentry, A. Fox, R. Kuhn, and J. Winter Metabotropic glutamate receptor 5 upregulation in A-fibers after spinal nerve injury: 2-methyl-6-(phenylethynyl)-pyridine (MPEP) reverses the induced thermal hyperalgesia J. Neurosci. 22 2002 2660 2668
9. W.A. Catterall Structure and function of voltage-gated ion channels Annu. Rev. Biochem. 64 1995 493 531
10. S.G. Waxman, S. Dib-Hajj, T.R. Cummins, and J.A. Black Sodium channels and pain Proc. Natl. Acad. Sci. USA 96 1999 7635 7639
11. J.N. Wood, J.P. Boorman, K. Okuse, and M.D. Baker Voltage-gated sodium channels and pain pathways J. Neurobiol. 61 2004 55 71
12. M. Chahine, R. Ziane, K. Vijayaragavan, and Y. Okamura Regulation of Na v channels in sensory neurons Trends Pharmacol. Sci. 26 2005 496 502
13. M. Hirade, H. Yasuda, M. Omatsu-Kanbe, R. Kikkawa, and H. Kitasato Tetrodotoxin-resistant sodium channels of dorsal root ganglion neurons are readily activated in diabetic rats Neuroscience 90 1999 933 939
14. M.J. Craner, J.P. Klein, M. Renganathan, J.A. Black, and S.G. Waxman Changes of sodium channel expression in experimental painful diabetic neuropathy Ann. Neurol. 52 2002 786 792
15. S. Hong, T.J. Morrow, P.E. Paulson, L.L. Isom, and J.W. Wiley Early painful diabetic neuropathy is associated with differential changes in tetrodotoxin-sensitive and -resistant sodium channels in dorsal root ganglion neurons in the rat J. Biol. Chem. 279 2004 29341 29350
16. M.J. Craner, A.C. Lo, J.A. Black, and S.G. Waxman Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination Brain 126 2003 1552 1561
17. T.R. Cummins, and S.G. Waxman Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury J. Neurosci. 17 1997 3503 3514
18. T.R. Cummins, S.D. Dib-Hajj, J.A. Black, A.N. Akopian, J.N. Wood, and S.G. Waxman A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons J. Neurosci. 19 1999 RC43
19. S.G. Waxman, T.R. Cummins, S.D. Dib-Hajj, and J.A. Black Voltage-gated sodium channels and the molecular pathogenesis of pain: a review J. Rehabil. Res. Dev. 37 2000 517 528
20. J.H. Caldwell, K.L. Schaller, R.S. Lasher, E. Peles, and S.R. Levinson Sodium channel Na(v)1. 6 is localized at nodes of ranvier, dendrites, and synapses Proc. Natl. Acad. Sci. USA 97 2000 5616 5620
21. J.C. Ulzheimer, E. Peles, S.R. Levinson, and R. Martini Altered expression of ion channel isoforms at the node of Ranvier in P0-deficient myelin mutants Mol. Cell Neurosci. 25 2004 83 94
22. J.J. Devaux, and S.S. Scherer Altered ion channels in an animal model of Charcot-Marie-Tooth disease type IA J. Neurosci. 25 2005 1470 1480
23. A.N. Akopian, V. Souslova, S. England, K. Okuse, N. Ogata, J. Ure, A. Smith, B.J. Kerr, S.B. McMahon, S. Boyce, R. Hill, L.C. Stanfa, A.H. Dickenson, and J.N. Wood The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways Nat. Neurosci. 2 1999 541 548
24. M.A. Nassar, L.C. Stirling, G. Forlani, M.D. Baker, E.A. Matthews, A.H. Dickenson, and J.N. Wood Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain Proc. Natl. Acad. Sci. USA 101 2004 12706 12711
25. M. Renganathan, T.R. Cummins, and S.G. Waxman Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons J. Neurophysiol. 86 2001 629 640
26. L. Djouhri, X. Fang, K. Okuse, J.N. Wood, C.M. Berry, and S. Lawson The TTX-resistant sodium channel Nav1.8 (SNS/PN3): expression and correlation with membrane properties in rat nociceptive primary afferent neurons J. Physiol. 2003
27. R.I. Herzog, T.R. Cummins, and S.G. Waxman Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons J. Neurophysiol. 86 2001 1351 1364
28. A.A. Sima, V. Nathaniel, V. Bril, T.A. McEwen, and D.A. Greene Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes, and demonstration of axo-glial dysjunction in human diabetic neuropathy J. Clin. Invest 81 1988 349 364
29. M.N. Rasband, T. Kagawa, E.W. Park, K. Ikenaka, and J.S. Trimmer Dysregulation of axonal sodium channel isoforms after adult-onset chronic demyelination J. Neurosci. Res. 73 2003 465 470
30. J.S. Chopra, B.B. Sawhney, and R.N. Chakravorty Pathology and time relationship of peripheral nerve changes in experimental diabetes J. Neurol. Sci. 32 1977 53 67
31. J.A. Kearney, D.A. Buchner, G. De Haan, M. Adamska, S.I. Levin, A.R. Furay, R.L. Albin, J.M. Jones, M. Montal, M.J. Stevens, L.K. Sprunger, and M.H. Meisler Molecular and pathological effects of a modifier gene on deficiency of the sodium channel Scn8a (Na(v)1. 6) Hum. Mol. Genet. 11 2002 2765 2775
32. M.H. Ossipov, D. Bian, T.P. Malan Jr., J. Lai, and F. Porreca Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats Pain 79 1999 127 133
33. S. Hong, and J.W. Wiley Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1 J. Biol. Chem. 2004
34. L.J. Hudson, S. Bevan, G. Wotherspoon, C. Gentry, A. Fox, and J. Winter VR1 protein expression increases in undamaged DRG neurons after partial nerve injury Eur. J. Neurosci. 13 2001 2105 2114
35. H.A. Lekan, S.M. Carlton, and R.E. Coggeshall Sprouting of A beta fibers into lamina II of the rat dorsal horn in peripheral neuropathy Neurosci. Lett. 208 1996 147 150
36. I. Kohama, K. Ishikawa, and J.D. Kocsis Synaptic reorganization in the substantia gelatinosa after peripheral nerve neuroma formation: aberrant innervation of lamina II neurons by Abeta afferents J. Neurosci. 20 2000 1538 1549