α-SNS Produces the Slow TTX-Resistant Sodium Current in Large Cutaneous Afferent DRG Neurons

Journal of Neurophysiology

Volumn 84, Issue 2, 2000, Pages 710-718

  Renganathan, M ^a   Cummins, T R ^a   Hormuzdiar, W N ^a   Waxman, S G ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROGOLD; SODIUM; SODIUM CHANNEL; TETRODOTOXIN;

ALPHA NERVE FIBER; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; KNOCKOUT GENE; MOUSE; NERVE FIBER C; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; SENSORY NERVE; SKIN NERVE; SLOW INWARD CURRENT; SODIUM CURRENT; SPINAL GANGLION;

EID: 0033837549     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2000.84.2.710     Document Type: Article

References (31)

1. A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons
2. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
3. Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs
4. Three types of sodium channels in adult rat dorsal root ganglion neurons
5. A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons
6. Slow closed-state inactivation: A novel mechanism underlying ramp currents in cells expressing the hNE/PN 1 sodium channel
7. Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury
8. Down-regulation of transcripts for Na channel alpha-SNS in spinal sensory neurons following axotomy
9. NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy
10. Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons
11. Coding sequence, genomic organization, and conserved chromosomal localization of the mouse gene Scn1 1a encoding the sodium channel NaN
12. Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia
13. Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons
14. Localization of the tetrodotoxin-resistant sodium channel NaN in nociceptors
15. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
16. Quantitative estimation of the effects of capsaicin on the mouse primary sensory neurons
17. Delayed depolarization and slow sodium currents in cutaneous afferents
18. Different effects of 4-aminopyridine on sensory and motor fibers: Pathogenesis of paresthesias
19. Maturation of mammalian myelinated fibers: Changes in action-potential characteristics following 4-aminopyridine application
20. Ionic currents in the somatic membrane of rat dorsal root ganglion neurons. I. Sodium currents
21. Subtypes of dorsal root ganglion neurons based on different inward currents as measured by whole-cell voltage clamp
22. Distribution of the tetrodotoxin-resistant sodium channel PN3 in rat sensory neurons in normal and neuropathic conditions
23. Evolution and diversity of mammalian sodium channel genes
24. + currents in axotomized C-type DRG neurons
25. Differential properties of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons
26. Structure and function of a novel voltage-gated, tetrodotoxin-resistant sodium channel specific to sensory neurons
27. + channel in rat dorsal root ganglion neurons and their blockade by halothane
28. 2+ stores exclusively in large DRG neurones
29. Two sodium channels contribute to the TIX-R sodium current in primary sensory neurons
30. Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons
31. Actions of capsaicin on mouse dorsal root ganglion cells in vitro