Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470

Molecular and Biochemical Parasitology

Volumn 168, Issue 2, 2009, Pages 158-167

  Alvarado, John Jeff ^a   Nemkal, Anjana ^a   Sauder, J Michael ^b   Russell, Marijane ^b   Akiyoshi, Donna E ^c   Shi, Wuxian ^d   Almo, Steven C ^a   Weiss, Louis M ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Eli Lilly   (United States)

^c TUFTS UNIVERSITY   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Encephalitozoon cuniculi; Enterocytozoon bieneusi; Methionine Aminopeptidase; Microsporidia; Therapeutics; X ray crystal structure

Indexed keywords

FUMAGILLIN; FUMAGILLOL CHLOROACETYLCARBAMATE; METHIONYL AMINOPEPTIDASE 2;

ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; COMPLEX FORMATION; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENTEROCYTOZOON; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; IN VITRO STUDY; MICROSPORIDA; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY;

AMINO ACID SEQUENCE; AMINOPEPTIDASES; ANIMALS; BACULOVIRIDAE; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; CYCLOHEXANES; ENCEPHALITOZOON CUNICULI; FATTY ACIDS, UNSATURATED; GENE EXPRESSION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SESQUITERPENES;

ANIMALIA; ENCEPHALITOZOON CUNICULI; ENTEROCYTOZOON BIENEUSI; INVERTEBRATA; MICROSPORIDIA; PROTISTA; VERTEBRATA;

EID: 70349270555     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2009.07.008     Document Type: Article

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