Physiologically relevant metal cofactor for methionine aminopeptidase-2 is manganese

Biochemistry

Volumn 42, Issue 17, 2003, Pages 5035-5042

  Wang, Jieyi ^a   Sheppard, George S ^a   Lou, Pingping ^a   Kawai, Megumi ^a   Park, Chang ^a   Egan, David A ^a   Schneider, Andrew ^a   Bouska, Jennifer ^a   Lesniewski, Rick ^a   Henkin, Jack ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CALCIUM; COBALT; GENETIC ENGINEERING; POSITIVE IONS;

ENZYME ACTIVITY;

ENZYMES;

(3 AMINO 2 HYDROXY 5 ETHYLTHIO)PENTANOYL[(1 NAPHTHYL)ETHYL]AMIDE; 3 [(2 NAPHTHYLMETHYL)SULFANYL] 4H 1,2,4 TRIAZOLE; A 310840; A 311263; CALCIUM; COBALT; COPPER; ENZYME INHIBITOR; IRON; MAGNESIUM; MANGANESE; METHIONINE; METHIONYL AMINOPEPTIDASE; METHIONYL AMINOPEPTIDASE 2; METHIONYLALANYLSERINE; METHIONYLALANYLSERYLLYSYLBIOTINYLGLYCINE; METHIONYLGLYCYLALANYLGLUTAMINYLPHENYLALANYLSERYLLYSYLTHREONINE; NICKEL; PEPTIDE; UNCLASSIFIED DRUG; ZINC;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); DRUG PENETRATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AMINOPEPTIDASES; APOENZYMES; BASE SEQUENCE; CATIONS, DIVALENT; DNA PRIMERS; HUMANS; KINETICS; MANGANESE; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS;

EID: 0038333336     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi020670c     Document Type: Article

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