-
1
-
-
27744565323
-
Structural basis for the functional differences between Type I and Type II human methionine aminopeptidases
-
Addlagatta, A., Hu, X., Liu, J.O., and Matthews, B.W. 2005. Structural basis for the functional differences between Type I and Type II human methionine aminopeptidases. Biochemistry 44: 14741-14749.
-
(2005)
Biochemistry
, vol.44
, pp. 14741-14749
-
-
Addlagatta, A.1
Hu, X.2
Liu, J.O.3
Matthews, B.W.4
-
2
-
-
0033617532
-
Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
-
Bergers, G., Javaherian, K., Lo, K.M., Folkman, J., and Hanahan, D. 1999. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science 284: 808-812.
-
(1999)
Science
, vol.284
, pp. 808-812
-
-
Bergers, G.1
Javaherian, K.2
Lo, K.M.3
Folkman, J.4
Hanahan, D.5
-
3
-
-
6544276582
-
A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer
-
Bhargava, P., Marshall, J.L., Rizvi, N., Dahut, W., Yoe, J., Figuera, M., Phipps, K., Ong, V.S., Kato, A., and Hawkins, M.J. 1999. A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer. Clin. Cancer Res. 5: 1989-1995.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 1989-1995
-
-
Bhargava, P.1
Marshall, J.L.2
Rizvi, N.3
Dahut, W.4
Yoe, J.5
Figuera, M.6
Phipps, K.7
Ong, V.S.8
Kato, A.9
Hawkins, M.J.10
-
4
-
-
1542274566
-
A single amino acid residue defines the difference in ovalicin sensitivity between Type I and II methionine aminopeptidases
-
Brdlik, C.M. and Crews, C.M. 2004. A single amino acid residue defines the difference in ovalicin sensitivity between Type I and II methionine aminopeptidases. J. Biol. Chem. 279: 9475-9480.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9475-9480
-
-
Brdlik, C.M.1
Crews, C.M.2
-
5
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brünger, A.T., Adams, P.D., Clore, G.M., DeLano, W.L., Gros, P., Grosse-Kunstleve, R.W., Jiang, J.S., Kuszewski, J., Nilges, M., Pannu, N.S., et al. 1998. Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 54: 905-921.
-
(1998)
Acta Crystallogr. D Biol. Crystallogr.
, vol.54
, pp. 905-921
-
-
Brünger, A.T.1
Adams, P.D.2
Clore, G.M.3
DeLano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
-
6
-
-
0035818432
-
Structural evidence that the methionyl aminopeptidase from Escherichia coli is a mononuclear metalloprotease
-
Cosper, N.J., D'Souza, V.M., Scott, R.A., and Holz, R.C. 2001. Structural evidence that the methionyl aminopeptidase from Escherichia coli is a mononuclear metalloprotease. Biochemistry 40: 13302-13309.
-
(2001)
Biochemistry
, vol.40
, pp. 13302-13309
-
-
Cosper, N.J.1
D'Souza, V.M.2
Scott, R.A.3
Holz, R.C.4
-
7
-
-
13144279326
-
Characterization of the active site and insight into the binding mode of the antiangiogenesis agent fumagillin to the manganese(II) loaded methionyl aminopeptidase from Escherichia coli
-
D'Souza, V.M., Brown, R.S., Bennett, B., and Holz, R.C. 2005. Characterization of the active site and insight into the binding mode of the antiangiogenesis agent fumagillin to the manganese(II) loaded methionyl aminopeptidase from Escherichia coli. J. Biol. Inorg. Chem. 10: 41-50.
-
(2005)
J. Biol. Inorg. Chem.
, vol.10
, pp. 41-50
-
-
D'Souza, V.M.1
Brown, R.S.2
Bennett, B.3
Holz, R.C.4
-
8
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman, J. 1971. Tumor angiogenesis: Therapeutic implications. N. Engl. J. Med. 285: 1182-1186.
-
(1971)
N. Engl. J. Med.
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
9
-
-
0031171961
-
Methionine aminopeptidase (Type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin
-
Griffith, E.C., Su, Z., Turk, B.E., Chen, S., Chang, Y.H., Wu, Z., Biemann, K., and Liu, J.O. 1997. Methionine aminopeptidase (Type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin. Chem. Biol. 4: 461-471.
-
(1997)
Chem. Biol.
, vol.4
, pp. 461-471
-
-
Griffith, E.C.1
Su, Z.2
Turk, B.E.3
Chen, S.4
Chang, Y.H.5
Wu, Z.6
Biemann, K.7
Liu, J.O.8
-
10
-
-
0037112010
-
Safety and pharmacokinetic effects of TNP-470, an angiogenesis inhibitor, combined with paclitaxel in patients with solid tumors: Evidence for activity in non-small cell lung cancer
-
Herbst, R.S., Madden, T.L., Tran, H.T., Blumenschein Jr., G.R., Meyers, C.A., Seabrooke, L.F., Khuri, F.R., Puduvalli, V.K., Allgood, V., Fritsche Jr., H.A., et al. 2002. Safety and pharmacokinetic effects of TNP-470, an angiogenesis inhibitor, combined with paclitaxel in patients with solid tumors: Evidence for activity in non-small cell lung cancer. J. Clin. Oncol. 20: 4440-4447.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 4440-4447
-
-
Herbst, R.S.1
Madden, T.L.2
Tran, H.T.3
Blumenschein Jr., G.R.4
Meyers, C.A.5
Seabrooke, L.F.6
Khuri, F.R.7
Puduvalli, V.K.8
Allgood, V.9
Fritsche Jr., H.A.10
-
11
-
-
0025204095
-
Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth
-
Ingber, D., Fujita, T., Kishimoto, S., Sudo, K., Kanamaru, T., Brem, H., and Folkman, J. 1990. Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature 348: 555-557.
-
(1990)
Nature
, vol.348
, pp. 555-557
-
-
Ingber, D.1
Fujita, T.2
Kishimoto, S.3
Sudo, K.4
Kanamaru, T.5
Brem, H.6
Folkman, J.7
-
12
-
-
0033081529
-
Rapid automated molecular replacement by evolutionary search
-
Kissinger, C.R., Gehlhaar, D.K., and Fogel, D.B. 1999. Rapid automated molecular replacement by evolutionary search. Acta Crystallogr. D Biol. Crystallogr. 55: 484-491.
-
(1999)
Acta Crystallogr. D Biol. Crystallogr.
, vol.55
, pp. 484-491
-
-
Kissinger, C.R.1
Gehlhaar, D.K.2
Fogel, D.B.3
-
13
-
-
0347481378
-
Protonation states of methionine aminopeptidase and their relevance for inhibitor binding and catalytic activity
-
Klein, C.D., Schiffmann, R., Folkers, G., Piana, S., and Rothlisberger, U. 2003. Protonation states of methionine aminopeptidase and their relevance for inhibitor binding and catalytic activity. J. Biol. Chem. 278: 47862-47867.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 47862-47867
-
-
Klein, C.D.1
Schiffmann, R.2
Folkers, G.3
Piana, S.4
Rothlisberger, U.5
-
15
-
-
0028013224
-
Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470)
-
Kusaka, M., Sudo, K., Matsutani, E., Kozai, Y., Marui, S., Fujita, T., Ingber, D., and Folkman, J. 1994. Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470). Br. J. Cancer 69: 212-216.
-
(1994)
Br. J. Cancer
, vol.69
, pp. 212-216
-
-
Kusaka, M.1
Sudo, K.2
Matsutani, E.3
Kozai, Y.4
Marui, S.5
Fujita, T.6
Ingber, D.7
Folkman, J.8
-
16
-
-
0032515029
-
Structure of human methionine aminopeptidase 2 complexed with fumagillin
-
Liu, S., Widom, J., Kemp, C.W., Crews, C.M., and Clardy, J. 1998. Structure of human methionine aminopeptidase 2 complexed with fumagillin. Science 282: 1324-1327.
-
(1998)
Science
, vol.282
, pp. 1324-1327
-
-
Liu, S.1
Widom, J.2
Kemp, C.W.3
Crews, C.M.4
Clardy, J.5
-
17
-
-
0034901968
-
Phase I trial of the angiogenesis inhibitor TNP-470 for progressive androgen independent prostate cancer
-
Logothetis, C.J., Wu, K.K., Finn, L.D., Daliani, D., Figg, W., Ghaddar, H., and Gutterman, J.U. 2001. Phase I trial of the angiogenesis inhibitor TNP-470 for progressive androgen independent prostate cancer. Clin. Cancer Res. 7: 1198-1203.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1198-1203
-
-
Logothetis, C.J.1
Wu, K.K.2
Finn, L.D.3
Daliani, D.4
Figg, W.5
Ghaddar, H.6
Gutterman, J.U.7
-
18
-
-
0032514659
-
The anti-angiogenic agent fumagillin covalently modifies a conserved active site histidine in the Escherichia coli methionine aminopeptidase
-
Lowther, W.T., McMillen, D.A., Orville, A.M., and Matthews, B.W. 1998. The anti-angiogenic agent fumagillin covalently modifies a conserved active site histidine in the Escherichia coli methionine aminopeptidase. Proc. Natl. Acad. Sci. 95: 12153-12157.
-
(1998)
Proc. Natl. Acad. Sci.
, vol.95
, pp. 12153-12157
-
-
Lowther, W.T.1
McMillen, D.A.2
Orville, A.M.3
Matthews, B.W.4
-
19
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
eds. C. Carter and R. Sweet, Academic Press, New York
-
Otwinowski, Z. and Minor, W. 1997. Processing of X-ray diffraction data collected in oscillation mode. In Macromolecular crystallography, part A (eds. C. Carter and R. Sweet), Vol. 276, pp. 307-326. Academic Press, New York.
-
(1997)
Macromolecular Crystallography, Part A
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
21
-
-
0030924753
-
The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2
-
Sin, N., Meng, L., Wang, M.Q., Wen, J.J., Bornmann, W.G., and Crews, C.M. 1997. The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2. Proc. Natl. Acad. Sci. 94: 6099-6103.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 6099-6103
-
-
Sin, N.1
Meng, L.2
Wang, M.Q.3
Wen, J.J.4
Bornmann, W.G.5
Crews, C.M.6
-
22
-
-
0032767386
-
Multi-institutional study of the angiogenesis inhibitor TNP-470 in metastatic renal carcinoma
-
Stadler, W.M., Kuzel, T., Shapiro, C., Sosman, J., Clark, J., and Vogelzang, N.J. 1999. Multi-institutional study of the angiogenesis inhibitor TNP-470 in metastatic renal carcinoma. J. Clin. Oncol. 17: 2541-2545.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2541-2545
-
-
Stadler, W.M.1
Kuzel, T.2
Shapiro, C.3
Sosman, J.4
Clark, J.5
Vogelzang, N.J.6
-
23
-
-
0028344887
-
Significant inhibition of endothelial cell growth in tumor vasculature by an angiogenesis inhibitor, TNP-470 (AGM-1470)
-
Yamamoto, T., Sudo, K., and Fujita, T. 1994. Significant inhibition of endothelial cell growth in tumor vasculature by an angiogenesis inhibitor, TNP-470 (AGM-1470). Anticancer Res. 14: 1-3.
-
(1994)
Anticancer Res.
, vol.14
, pp. 1-3
-
-
Yamamoto, T.1
Sudo, K.2
Fujita, T.3
-
24
-
-
0027487871
-
Angiogenesis inhibitor TNP-470 (AGM-1470) potently inhibits the tumor growth of hormone-independent human breast and prostate carcinoma cell lines
-
Yamaoka, M., Yamamoto, T., Ikeyama, S., Sudo, K., and Fujita, T. 1993a. Angiogenesis inhibitor TNP-470 (AGM-1470) potently inhibits the tumor growth of hormone-independent human breast and prostate carcinoma cell lines. Cancer Res. 53: 5233-5236.
-
(1993)
Cancer Res.
, vol.53
, pp. 5233-5236
-
-
Yamaoka, M.1
Yamamoto, T.2
Ikeyama, S.3
Sudo, K.4
Fujita, T.5
-
25
-
-
0027853194
-
Inhibition of tumor growth and metastasis of rodent tumors by the angiogenesis inhibitor O (chloroacetyl carbamoyl)fumagillol (TNP-470; AGM-1470)
-
Yamaoka, M., Yamamoto, T., Masaki, T., Ikeyama, S., Sudo, K., and Fujita, T. 1993b. Inhibition of tumor growth and metastasis of rodent tumors by the angiogenesis inhibitor O (chloroacetyl carbamoyl)fumagillol (TNP-470; AGM-1470). Cancer Res. 53: 4262-4267.
-
(1993)
Cancer Res.
, vol.53
, pp. 4262-4267
-
-
Yamaoka, M.1
Yamamoto, T.2
Masaki, T.3
Ikeyama, S.4
Sudo, K.5
Fujita, T.6
-
26
-
-
0042343842
-
Fumagalone, a reversible inhibitor of Type 2 methionine aminopeptidase and angiogenesis
-
Zhou, G., Tsai, C.W., and Liu, J.O. 2003. Fumagalone, a reversible inhibitor of Type 2 methionine aminopeptidase and angiogenesis. J. Med. Chem. 46: 3452-3454.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 3452-3454
-
-
Zhou, G.1
Tsai, C.W.2
Liu, J.O.3
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