Enantiopure sulforaphane analogues with various substituents at the sulfinyl sulfur: Asymmetric synthesis and biological activities

Journal of Organic Chemistry

Volumn 74, Issue 16, 2009, Pages 6002-6009

  Khiar, Noureddine ^a   Werner, Sabine ^c   Mallouk, Siham ^a   Lieder, Franziska ^c   Alcudia, Ana ^b   Fernández, Inmaculada ^b  

^a INSTITUTO DE INVESTIGACIONES QUÍMICAS   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL REACTIONS; ELECTRON TRANSITIONS; ESTERS; SULFUR; TRANSCRIPTION FACTORS;

ASYMMETRIC SYNTHESIS; BIOLOGICAL ACTIVITIES; CHEMICAL EQUATIONS; DETOXIFYING ENZYMES; DIASTEREOSELECTIVE SYNTHESIS; ENANTIOPURE; PHASE II; SULFINATE ESTERS; SULFORAPHANE;

BIOACTIVITY;

(1,2:5,6 DI O ISOPROPYLIDENE ALPHA GLUCOFURANOSYL) 4 AZIDOBUTANESULFINATE; (4 AZIDOBUTYLSULFINYL)CYCLOHEXANE; (4 ISOTHIOCYANATOBUTYLSULFINYL)CYCLOHEXANE; 1 (4 AZIDOBUTYLSULFINYL)PENTANE; 1 (4 ISOTHIOCYANATOBUTYLSULFINYL)PENTANE; 1 AZIDO 4 (METHYLSULFINYL)BUTANE; 1 ISOCYANATO 4 (METHYLSULFINYL)BUTANE; 11 (4 AZIDOBUTYLSULFINYL)UNDEC 1 ENE; 11 (4 ISOTHIOCYANATOBUTYLSULFINYL)UNDEC 1 ENE; 2 (4 AZIDOBUTYLSULFINYL)NAPHTHALENE; 4 AZIDOBUTAN 1 OL; 4 AZIDOBUTANE 1 SULFINYL CHLORIDE; 4 AZIDOBUTYL 1 THIOACETATE; 4 AZIDOBUTYL METHANESULFONATE; 4 HYDROXYBUTYL METHANESULFONATE; SULFORAPHANE; SULFUR DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ANTIOXIDANT; ISOTHIOCYANIC ACID DERIVATIVE; SULFORAFAN; SULFUR; THIOCYANIC ACID DERIVATIVE; TRANSCRIPTION FACTOR NRF2;

ARTICLE; ASYMMETRIC SYNTHESIS; BIOLOGICAL ACTIVITY; ENANTIOSELECTIVITY; ANIMAL; CELL LINE; CELL PROTECTION; CHEMISTRY; DNA RESPONSIVE ELEMENT; DOSE RESPONSE; DRUG DETOXIFICATION; DRUG EFFECTS; ENZYME INDUCTION; GENETICS; HUMAN; METABOLISM; RAT; STEREOISOMERISM; SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CELL LINE; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; HUMANS; ISOTHIOCYANATES; METABOLIC DETOXICATION, PHASE II; NF-E2-RELATED FACTOR 2; RATS; RESPONSE ELEMENTS; STEREOISOMERISM; SULFUR; THIOCYANATES;

EID: 70349101647     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9007749     Document Type: Article

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