Vibrio cholerae proteome-wide screen for immunostimulatory proteins identifies phosphatidylserine decarboxylase as a novel toll-like receptor 4 agonist

PLoS Pathogens

Volumn 5, Issue 8, 2009, Pages

  Thanawastien, Ann ^a   Montor, Wagner R ^a   Labaer, Joshua ^a   Mekalanos, John J ^a   Yoon, Sang Sun ^a,b,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c Yonsei University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHATIDYLSERINE DECARBOXYLASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; CARBOXYLYASE; IMMUNOLOGICAL ADJUVANT; MYD88 PROTEIN, MOUSE; PROTEOME; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; FEMALE; HIGH THROUGHPUT SCREENING; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOSTIMULATION; INNATE IMMUNITY; MOUSE; NONHUMAN; PERITONEUM CELL; PERITONEUM MACROPHAGE; PROTEOMICS; SIGNAL TRANSDUCTION; VIBRIO CHOLERAE; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; METHODOLOGY;

BACTERIA (MICROORGANISMS); MURINAE; MUS; VIBRIO CHOLERAE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CARBOXY-LYASES; FEMALE; HOST-PATHOGEN INTERACTIONS; INTERLEUKIN-6; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; MYELOID DIFFERENTIATION FACTOR 88; PROTEOME; PROTEOMICS; SERUM ALBUMIN, BOVINE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; VIBRIO CHOLERAE;

EID: 70049088449     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000556     Document Type: Article

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