Genomic approaches to understanding bacterial virulence

Current Opinion in Microbiology

Volumn 10, Issue 1, 2007, Pages 4-9

  Burrack, Laura S ^a   Higgins, Darren E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

BACTERIAL GENOME; BACTERIAL VIRULENCE; GENE EXPRESSION SYSTEM; GENE LIBRARY; GENE SEQUENCE; MUTANT; NONHUMAN; REVIEW; YEAST;

BACTERIA; GENOME, BACTERIAL; GENOMICS; VIRULENCE;

BACTERIA (MICROORGANISMS);

EID: 33846783021     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mib.2006.11.004     Document Type: Review

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32. ••], this work describes the first genome-wide screen for host cell proteins required for infection by an intracellular bacterial pathogen. This study also identified the CD36 host receptor as important for uptake of mycobacterial species.
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34. ••] this work describes the first genome-wide screen for host cell proteins required for infection by an intracellular bacterial pathogen. This work also compares and contrasts the requirements of host factors for a cytosolic pathogen, L. monocytogenes, with those of a vacuolar pathogen, M. fortuitum.
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