-
1
-
-
0034699512
-
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia
-
Allen, T. M., D. H. O'Connor, P. Jing, J. L. Dzuris, B. R. Mothe, T. U. Vogel, E. Dunphy, M. E. Liebl, C. Emerson, N. Wilson, K. J. Kunstman, X. Wang, D. B. Allison, A. L. Hughes, R. C. Desrosiers, J. D. Altman, S. M. Wolinsky, A. Sette, and D. I. Watkins. 2000. Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature 407:386-390.
-
(2000)
Nature
, vol.407
, pp. 386-390
-
-
Allen, T.M.1
O'Connor, D.H.2
Jing, P.3
Dzuris, J.L.4
Mothe, B.R.5
Vogel, T.U.6
Dunphy, E.7
Liebl, M.E.8
Emerson, C.9
Wilson, N.10
Kunstman, K.J.11
Wang, X.12
Allison, D.B.13
Hughes, A.L.14
Desrosiers, R.C.15
Altman, J.D.16
Wolinsky, S.M.17
Sette, A.18
Watkins, D.I.19
-
2
-
-
0037367965
-
T-cell epitope mapping using the ELISPOT approach
-
Anthony, D. D., and P. V. Lehmann. 2003. T-cell epitope mapping using the ELISPOT approach. Methods 29:260-269.
-
(2003)
Methods
, vol.29
, pp. 260-269
-
-
Anthony, D.D.1
Lehmann, P.V.2
-
3
-
-
0037122796
-
Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes
-
Barouch, D. H., J. Kunstman, M. J. Kuroda, J. E. Schmitz, S. Santra, F. W. Peyerl, G. R. Krivulka, K. Beaudry, M. A. Lifton, D. A. Gorgone, D. C. Montefiori, M. G. Lewis, S. M. Wolinsky, and N. L. Letvin. 2002. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature 415:335-339.
-
(2002)
Nature
, vol.415
, pp. 335-339
-
-
Barouch, D.H.1
Kunstman, J.2
Kuroda, M.J.3
Schmitz, J.E.4
Santra, S.5
Peyerl, F.W.6
Krivulka, G.R.7
Beaudry, K.8
Lifton, M.A.9
Gorgone, D.A.10
Montefiori, D.C.11
Lewis, M.G.12
Wolinsky, S.M.13
Letvin, N.L.14
-
5
-
-
0028360076
-
Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells
-
DOI 10.1038/369407a0
-
Bertoletti, A., A. Sette, F. V. Chisari, A. Penna, M. Levrero, M. De Carli, F. Fiaccadori, and C. Ferrari. 1994. Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells. Nature 369:407-410. (Pubitemid 24184055)
-
(1994)
Nature
, vol.369
, Issue.6479
, pp. 407-410
-
-
Bertoletti, A.1
Sette, A.2
Chisari, F.V.3
Penna, A.4
Levrero, M.5
De Carli, M.6
Fiaccadori, F.7
Ferrari, C.8
-
7
-
-
0028041344
-
+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
-
Borrow, P., H. Lewicki, B. H. Hahn, G. M. Shaw, and M. B. Oldstone. 1994. Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J. Virol. 68:6103-6110. (Pubitemid 24258634)
-
(1994)
Journal of Virology
, vol.68
, Issue.9
, pp. 6103-6110
-
-
Borrow, P.1
Lewicki, H.2
Hahn, B.H.3
Shaw, G.M.4
Oldstone, M.B.A.5
-
8
-
-
16944365445
-
Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
-
Borrow, P., H. Lewicki, X. Wei, M. S. Horwitz, N. Peffer, H. Meyers, J. A. Nelson, J. E. Gairin, B. H. Hahn, M. B. Oldstone, and G. M. Shaw. 1997. Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nat. Med. 3:205-211.
-
(1997)
Nat. Med.
, vol.3
, pp. 205-211
-
-
Borrow, P.1
Lewicki, H.2
Wei, X.3
Horwitz, M.S.4
Peffer, N.5
Meyers, H.6
Nelson, J.A.7
Gairin, J.E.8
Hahn, B.H.9
Oldstone, M.B.10
Shaw, G.M.11
-
11
-
-
0025761245
-
High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection
-
Clark, S. J., M. S. Saag, W. D. Decker, S. Campbell-Hill, J. L. Roberson, P. J. Veldkamp, J. C. Kappes, B. H. Hahn, and G. M. Shaw. 1991. High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection. N. Engl. J. Med. 324:954-960.
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 954-960
-
-
Clark, S.J.1
Saag, M.S.2
Decker, W.D.3
Campbell-Hill, S.4
Roberson, J.L.5
Veldkamp, P.J.6
Kappes, J.C.7
Hahn, B.H.8
Shaw, G.M.9
-
12
-
-
0025735965
-
Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection
-
Daar, E. S., T. Moudgil, R. D. Meyer, and D. D. Ho. 1991. Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection. N. Engl. J. Med. 324:961-964.
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 961-964
-
-
Daar, E.S.1
Moudgil, T.2
Meyer, R.D.3
Ho, D.D.4
-
13
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
Day, C. L., D. E. Kaufmann, P. Kiepiela, J. A. Brown, E. S. Moodley, S. Reddy, E. W. Mackey, J. D. Miller, A. J. Leslie, C. DePierres, Z. Mncube, J. Duraiswamy, B. Zhu, Q. Eichbaum, M. Altfeld, E. J. Wherry, H. M. Coovadia, P. J. Goulder, P. Klenerman, R. Ahmed, G. J. Freeman, and B. D. Walker. 2006. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443:350-354.
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
DePierres, C.10
Mncube, Z.11
Duraiswamy, J.12
Zhu, B.13
Eichbaum, Q.14
Altfeld, M.15
Wherry, E.J.16
Coovadia, H.M.17
Goulder, P.J.18
Klenerman, P.19
Ahmed, R.20
Freeman, G.J.21
Walker, B.D.22
more..
-
14
-
-
0037007670
-
+ T cells
-
+ T cells. Nature 417:95-98.
-
(2002)
Nature
, vol.417
, pp. 95-98
-
-
Douek, D.C.1
Brenchley, J.M.2
Betts, M.R.3
Ambrozak, D.R.4
Hill, B.J.5
Okamoto, Y.6
Casazza, J.P.7
Kuruppu, J.8
Kunstman, K.9
Wolinsky, S.10
Grossman, Z.11
Dybul, M.12
Oxenius, A.13
Price, D.A.14
Connors, M.15
Koup, R.A.16
-
15
-
-
0030693391
-
Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein
-
DOI 10.1126/science.278.5339.849
-
Gamble, T. R., S. Yoo, F. F. Vajdos, U. K. von Schwedler, D. K. Worthylake, H. Wang, J. P. McCutcheon, W. I. Sundquist, and C. P. Hill. 1997. Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein. Science 278:849-853. (Pubitemid 27467920)
-
(1997)
Science
, vol.278
, Issue.5339
, pp. 849-853
-
-
Gamble, T.R.1
Yoo, S.2
Vajdos, F.F.3
Von Schwedler, U.K.4
Worthylake, D.K.5
Wang, H.6
McCutcheon, J.P.7
Sundquist, W.I.8
Hill, C.P.9
-
16
-
-
0032538917
-
HIV-1 variation diminishes CD4 T lymphocyte recognition
-
Harcourt, G. C., S. Garrard, M. P. Davenport, A. Edwards, and R. E. Phillips. 1998. HIV-1 variation diminishes CD4 T lymphocyte recognition. J. Exp. Med. 188:1785-1793.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1785-1793
-
-
Harcourt, G.C.1
Garrard, S.2
Davenport, M.P.3
Edwards, A.4
Phillips, R.E.5
-
18
-
-
9244254245
-
+ cytotoxic T lymphocyte response
-
+ cytotoxic T lymphocyte response. J. Exp. Med. 200:1243-1256.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1243-1256
-
-
Jones, N.A.1
Wei, X.2
Flower, D.R.3
Wong, M.4
Michor, F.5
Saag, M.S.6
Hahn, B.H.7
Nowak, M.A.8
Shaw, G.M.9
Borrow, P.10
-
19
-
-
58149277359
-
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
-
Jones, R. B., L. C. Ndhlovu, J. D. Barbour, P. M. Sheth, A. R. Jha, B. R. Long, J. C. Wong, M. Satkunarajah, M. Schweneker, J. M. Chapman, G. Gyenes, B. Vali, M. D. Hyrcza, F. Y. Yue, C. Kovacs, A. Sassi, M. Loutfy, R. Halpenny, D. Persad, G. Spotts, F. M. Hecht, T. W. Chun, J. M. McCune, R. Kaul, J. M. Rini, D. F. Nixon, and M. A. Ostrowski. 2008. Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J. Exp. Med. 205:2763-2779.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2763-2779
-
-
Jones, R.B.1
Ndhlovu, L.C.2
Barbour, J.D.3
Sheth, P.M.4
Jha, A.R.5
Long, B.R.6
Wong, J.C.7
Satkunarajah, M.8
Schweneker, M.9
Chapman, J.M.10
Gyenes, G.11
Vali, B.12
Hyrcza, M.D.13
Yue, F.Y.14
Kovacs, C.15
Sassi, A.16
Loutfy, M.17
Halpenny, R.18
Persad, D.19
Spotts, G.20
Hecht, F.M.21
Chun, T.W.22
McCune, J.M.23
Kaul, R.24
Rini, J.M.25
Nixon, D.F.26
Ostrowski, M.A.27
more..
-
20
-
-
34548680261
-
+ T cells correlates with disease progression and defines a reversible immune dysfunction
-
+ T cells correlates with disease progression and defines a reversible immune dysfunction. Nat. Immunol. 8:1246-1254.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1246-1254
-
-
Kaufmann, D.E.1
Kavanagh, D.G.2
Pereyra, F.3
Zaunders, J.J.4
Mackey, E.W.5
Miura, T.6
Palmer, S.7
Brockman, M.8
Rathod, A.9
Piechocka-Trocha, A.10
Baker, B.11
Zhu, B.12
Le Gall, S.13
Waring, M.T.14
Ahern, R.15
Moss, K.16
Kelleher, A.D.17
Coffin, J.M.18
Freeman, G.J.19
Rosenberg, E.S.20
Walker, B.D.21
more..
-
21
-
-
15744361847
-
Limited durability of viral control following treated acute HIV infection
-
Kaufmann, D. E., M. Lichterfeld, M. Altfeld, M. M. Addo, M. N. Johnston, P. K. Lee, B. S. Wagner, E. T. Kalife, D. Strick, E. S. Rosenberg, and B. D. Walker. 2004. Limited durability of viral control following treated acute HIV infection. PLoS Med. 1:e36.
-
(2004)
PLoS Med.
, vol.1
-
-
Kaufmann, D.E.1
Lichterfeld, M.2
Altfeld, M.3
Addo, M.M.4
Johnston, M.N.5
Lee, P.K.6
Wagner, B.S.7
Kalife, E.T.8
Strick, D.9
Rosenberg, E.S.10
Walker, B.D.11
-
22
-
-
0028261060
-
Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants
-
DOI 10.1038/369403a0
-
Klenerman, P., S. Rowland-Jones, S. McAdam, J. Edwards, S. Daenke, D. Lalloo, B. Koppe, W. Rosenberg, D. Boyd, A. Edwards, et al. 1994. Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants. Nature 369:403-407. (Pubitemid 24184054)
-
(1994)
Nature
, vol.369
, Issue.6479
, pp. 403-407
-
-
Klenerman, P.1
Rowland-Jones, S.2
McAdam, S.3
Edwards, J.4
Daenke, S.5
Lalloo, D.6
Koppe, B.7
Rosenberg, W.8
Boyd, D.9
Edwards, A.10
Giangrande, P.11
Phillips, R.E.12
McMichael, A.J.13
-
24
-
-
0028337166
-
Temporal association of cellular immune responses with the initial control of viremia in primary human immunode- Ficiency virus type 1 syndrome
-
Koup, R. A., J. T. Safrit, Y. Cao, C. A. Andrews, G. McLeod, W. Borkowsky, C. Farthing, and D. D. Ho. 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunode- ficiency virus type 1 syndrome. J. Virol. 68:4650-4655.
-
(1994)
J. Virol.
, vol.68
, pp. 4650-4655
-
-
Koup, R.A.1
Safrit, J.T.2
Cao, Y.3
Andrews, C.A.4
McLeod, G.5
Borkowsky, W.6
Farthing, C.7
Ho, D.D.8
-
25
-
-
0013610170
-
Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus
-
Kovacs, J. A., S. Vogel, J. M. Albert, J. Falloon, R. T. Davey, Jr., R. E. Walker, M. A. Polis, K. Spooner, J. A. Metcalf, M. Baseler, G. Fyfe, and H. C. Lane. 1996. Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus. N. Engl. J. Med. 335:1350-1356.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1350-1356
-
-
Kovacs, J.A.1
Vogel, S.2
Albert, J.M.3
Falloon, J.4
Davey Jr., R.T.5
Walker, R.E.6
Polis, M.A.7
Spooner, K.8
Metcalf, J.A.9
Baseler, M.10
Fyfe, G.11
Lane, H.C.12
-
26
-
-
4644249757
-
+ T cells
-
+ T cells. J. Exp. Med. 200:701-712.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 701-712
-
-
Lichterfeld, M.1
Kaufmann, D.E.2
Yu, X.G.3
Mui, S.K.4
Addo, M.M.5
Johnston, M.N.6
Cohen, D.7
Robbins, G.K.8
Pae, E.9
Alter, G.10
Wurcel, A.11
Stone, D.12
Rosenberg, E.S.13
Walker, B.D.14
Altfeld, M.15
-
27
-
-
0028342554
-
Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis
-
Mammano, F., A. Ohagen, S. Hoglund, and H. G. Gottlinger. 1994. Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis. J. Virol. 68:4927-4936. (Pubitemid 24226558)
-
(1994)
Journal of Virology
, vol.68
, Issue.8
, pp. 4927-4936
-
-
Mammano, F.1
Ohagen, A.2
Hoglund, S.3
Gottlinger, H.G.4
-
30
-
-
0034608653
-
+ T cell depletion on virus replication in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine
-
+ T cell depletion on virus replication in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine. J. Exp. Med. 191:1921-1931.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1921-1931
-
-
Metzner, K.J.1
Jin, X.2
Lee, F.V.3
Gettie, A.4
Bauer, D.E.5
Di Mascio, M.6
Perelson, A.S.7
Marx, P.A.8
Ho, D.D.9
Kostrikis, L.G.10
Connor, R.I.11
-
31
-
-
10044238097
-
+-T-lymphocyte selection in simian immunodeficiency virus sequence variation
-
+-T-lymphocyte selection in simian immunodeficiency virus sequence variation. J. Virol. 78:14012-14022.
-
(2004)
J. Virol.
, vol.78
, pp. 14012-14022
-
-
O'Connor, D.H.1
McDermott, A.B.2
Krebs, K.C.3
Dodds, E.J.4
Miller, J.E.5
Gonzalez, E.J.6
Jacoby, T.J.7
Yant, L.8
Piontkivska, H.9
Pantophlet, R.10
Burton, D.R.11
Rehrauer, W.M.12
Wilson, N.13
Hughes, A.L.14
Watkins, D.I.15
-
32
-
-
33749338938
-
+ T cell survival in HIV infection
-
+ T cell survival in HIV infection. J. Exp. Med. 203:2281-2292.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2281-2292
-
-
Petrovas, C.1
Casazza, J.P.2
Brenchley, J.M.3
Price, D.A.4
Gostick, E.5
Adams, W.C.6
Precopio, M.L.7
Schacker, T.8
Roederer, M.9
Douek, D.C.10
Koup, R.A.11
-
33
-
-
0025827529
-
Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition
-
Phillips, R. E., S. Rowland-Jones, D. F. Nixon, F. M. Gotch, J. P. Edwards, A. O. Ogunlesi, J. G. Elvin, J. A. Rothbard, C. R. Bangham, C. R. Rizza, et al. 1991. Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature 354:453-459.
-
(1991)
Nature
, vol.354
, pp. 453-459
-
-
Phillips, R.E.1
Rowland-Jones, S.2
Nixon, D.F.3
Gotch, F.M.4
Edwards, J.P.5
Ogunlesi, A.O.6
Elvin, J.G.7
Rothbard, J.A.8
Bangham, C.R.9
Rizza, C.R.10
-
34
-
-
0031048597
-
Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection
-
Price, D. A., P. J. Goulder, P. Klenerman, A. K. Sewell, P. J. Easterbrook, M. Troop, C. R. Bangham, and R. E. Phillips. 1997. Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection. Proc. Natl. Acad. Sci. USA 94:1890-1895.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1890-1895
-
-
Price, D.A.1
Goulder, P.J.2
Klenerman, P.3
Sewell, A.K.4
Easterbrook, P.J.5
Troop, M.6
Bangham, C.R.7
Phillips, R.E.8
-
36
-
-
0028345391
-
Antigen analogs/MHC complexes as specific T cell receptor antagonists
-
Sette, A., J. Alexander, J. Ruppert, K. Snoke, A. Franco, G. Ishioka, and H. M. Grey. 1994. Antigen analogs/MHC complexes as specific T cell receptor antagonists. Annu. Rev. Immunol. 12:413-431.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 413-431
-
-
Sette, A.1
Alexander, J.2
Ruppert, J.3
Snoke, K.4
Franco, A.5
Ishioka, G.6
Grey, H.M.7
-
37
-
-
0037432787
-
Requirement for CD4 T cell help in generating functional CD8 T cell memory
-
DOI 10.1126/science.1082305
-
Shedlock, D. J., and H. Shen. 2003. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300:337-339. (Pubitemid 36433726)
-
(2003)
Science
, vol.300
, Issue.5617
, pp. 337-339
-
-
Shedlock, D.J.1
Shen, H.2
-
38
-
-
0029933309
-
Altered peptide ligand-induced partial T cell activation: Molecular mechanisms and role in T cell biology
-
Sloan-Lancaster, J., and P. M. Allen. 1996. Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu. Rev. Immunol. 14:1-27.
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 1-27
-
-
Sloan-Lancaster, J.1
Allen, P.M.2
-
39
-
-
0037432776
-
Defective CD8 T cell memory following acute infection without CD4 T cell help
-
Sun, J. C., and M. J. Bevan. 2003. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300:339-342.
-
(2003)
Science
, vol.300
, pp. 339-342
-
-
Sun, J.C.1
Bevan, M.J.2
-
40
-
-
33749009709
-
+ T cells leads to reversible immune dysfunction
-
+ T cells leads to reversible immune dysfunction. Nat. Med. 12:1198-1202.
-
(2006)
Nat. Med.
, vol.12
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
Said, E.A.4
Gimmig, S.5
Bessette, B.6
Boulassel, M.R.7
Delwart, E.8
Sepulveda, H.9
Balderas, R.S.10
Routy, J.P.11
Haddad, E.K.12
Sekaly, R.P.13
-
41
-
-
0025728301
-
Form, function, and use of retroviral gag proteins
-
Wills, J. W., and R. C. Craven. 1991. Form, function, and use of retroviral gag proteins. AIDS 5:639-654.
-
(1991)
AIDS
, vol.5
, pp. 639-654
-
-
Wills, J.W.1
Craven, R.C.2
-
42
-
-
0001771498
-
Evolution in Mendelian populations
-
Wright, S. 1931. Evolution in Mendelian populations. Genetics 16:97-159.
-
(1931)
Genetics
, vol.16
, pp. 97-159
-
-
Wright, S.1
-
45
-
-
0032416085
-
Viral immune evasion due to persistence of activated T cells without effector function
-
Zajac, A. J., J. N. Blattman, K. Murali-Krishna, D. J. Sourdive, M. Suresh, J. D. Altman, and R. Ahmed. 1998. Viral immune evasion due to persistence of activated T cells without effector function. J. Exp. Med. 188:2205-2213.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2205-2213
-
-
Zajac, A.J.1
Blattman, J.N.2
Murali-Krishna, K.3
Sourdive, D.J.4
Suresh, M.5
Altman, J.D.6
Ahmed, R.7
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