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Volumn 1, Issue , 2004, Pages 137-148

Limited durability of viral control following treated acute HIV infection

Author keywords

[No Author keywords available]

Indexed keywords

INDINAVIR; LAMIVUDINE; NELFINAVIR; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; VIRUS RNA; ZIDOVUDINE;

EID: 15744361847     PISSN: 15491277     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pmed.0010036     Document Type: Article
Times cited : (157)

References (64)
  • 1
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
    • Palella FJ Jr, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, et al. (1998) Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 338: 853-860.
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella Jr., F.J.1    Delaney, K.M.2    Moorman, A.C.3    Loveless, M.O.4    Fuhrer, J.5
  • 2
    • 0032953920 scopus 로고    scopus 로고
    • Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
    • Finzi D, Blankson J, Siliciano JD, Margolick JB, Chadwick K, et al. (1999) Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat Med 5: 512-517.
    • (1999) Nat Med , vol.5 , pp. 512-517
    • Finzi, D.1    Blankson, J.2    Siliciano, J.D.3    Margolick, J.B.4    Chadwick, K.5
  • 3
    • 0035912249 scopus 로고    scopus 로고
    • HIV chemotherapy
    • Richman DD (2001) HIV chemotherapy. Nature 410: 995-1001.
    • (2001) Nature , vol.410 , pp. 995-1001
    • Richman, D.D.1
  • 4
    • 0037108925 scopus 로고    scopus 로고
    • Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection
    • Oxenius A, Price DA, Gunthard HF, Dawson SJ, Fagard C, et al. (2002) Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection. Proc Natl Acad Sci U S A 99: 13747-13752.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13747-13752
    • Oxenius, A.1    Price, D.A.2    Gunthard, H.F.3    Dawson, S.J.4    Fagard, C.5
  • 5
    • 0038025296 scopus 로고    scopus 로고
    • A prospective trial of structured treatment interruptions in human immunodeficiency virus infection
    • Fagard C, Oxenius A, Gunthard H, Garcia F, Le Braz M, et al. (2003) A prospective trial of structured treatment interruptions in human immunodeficiency virus infection. Arch Intern Med 163: 1220-1226.
    • (2003) Arch Intern Med , vol.163 , pp. 1220-1226
    • Fagard, C.1    Oxenius, A.2    Gunthard, H.3    Garcia, F.4    Le Braz, M.5
  • 7
    • 0034711393 scopus 로고    scopus 로고
    • Control of SIV rebound through structured treatment interruptions during early infection
    • Lori F, Lewis MG, Xu J, Varga G, Zinn DE Jr, et al. (2000) Control of SIV rebound through structured treatment interruptions during early infection. Science 290: 1591-1593.
    • (2000) Science , vol.290 , pp. 1591-1593
    • Lori, F.1    Lewis, M.G.2    Xu, J.3    Varga, G.4    Zinn Jr., D.E.5
  • 8
  • 9
    • 0036720475 scopus 로고    scopus 로고
    • Discontinuation of antiretroviral therapy commenced early during the course of human immunodeficiency virus type 1 infection, with or without adjunctive vaccination
    • Markowitz M, Jin X, Hurley A, Simon V, Ramratnam B, et al. (2002) Discontinuation of antiretroviral therapy commenced early during the course of human immunodeficiency virus type 1 infection, with or without adjunctive vaccination. J Infect Dis 186: 634-643.
    • (2002) J Infect Dis , vol.186 , pp. 634-643
    • Markowitz, M.1    Jin, X.2    Hurley, A.3    Simon, V.4    Ramratnam, B.5
  • 10
    • 12144285675 scopus 로고    scopus 로고
    • HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication
    • Hess C, Altfeld M, Thomas SY, Addo MM, Rosenberg ES, et al. (2004) HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication. Lancet 363: 863-866.
    • (2004) Lancet , vol.363 , pp. 863-866
    • Hess, C.1    Altfeld, M.2    Thomas, S.Y.3    Addo, M.M.4    Rosenberg, E.S.5
  • 11
    • 0033615280 scopus 로고    scopus 로고
    • Reduced antiretroviral drug susceptibility among patients with primary HIV infection
    • Little SJ, Daar ES, D'Aquila RT, Keiser PH, Connick E, et al. (1999) Reduced antiretroviral drug susceptibility among patients with primary HIV infection. JAMA 282: 1142-1149.
    • (1999) JAMA , vol.282 , pp. 1142-1149
    • Little, S.J.1    Daar, E.S.2    D'Aquila, R.T.3    Keiser, P.H.4    Connick, E.5
  • 12
    • 0037043652 scopus 로고    scopus 로고
    • Antiretroviral-drug resistance among patients recently infected with HIV
    • Little SJ, Holte S, Routy JP, Daar ES, Markowitz M, et al. (2002) Antiretroviral-drug resistance among patients recently infected with HIV. N Engl J Med 347: 385-394.
    • (2002) N Engl J Med , vol.347 , pp. 385-394
    • Little, S.J.1    Holte, S.2    Routy, J.P.3    Daar, E.S.4    Markowitz, M.5
  • 13
    • 1842741699 scopus 로고    scopus 로고
    • HIV evolution: CTL escape mutation and reversion after transmission
    • Leslie AJ, Pfafferott KJ, Chetty P, Draenert R, Addo MM, et al. (2004) HIV evolution: CTL escape mutation and reversion after transmission. Nat Med 10: 282-289.
    • (2004) Nat Med , vol.10 , pp. 282-289
    • Leslie, A.J.1    Pfafferott, K.J.2    Chetty, P.3    Draenert, R.4    Addo, M.M.5
  • 14
    • 0032403159 scopus 로고    scopus 로고
    • Impact of hepatitis G virus co-infection on the course of hepatitis C virus infection before and after liver transplantation
    • Bizollon T, Guichard S, Ahmed SN, Chevallier P, Ducerf C, et al. (1998) Impact of hepatitis G virus co-infection on the course of hepatitis C virus infection before and after liver transplantation. J Hepatol 29: 893-900.
    • (1998) J Hepatol , vol.29 , pp. 893-900
    • Bizollon, T.1    Guichard, S.2    Ahmed, S.N.3    Chevallier, P.4    Ducerf, C.5
  • 15
    • 15844388931 scopus 로고    scopus 로고
    • Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
    • Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, et al. (1996) Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86: 367-377.
    • (1996) Cell , vol.86 , pp. 367-377
    • Liu, R.1    Paxton, W.A.2    Choe, S.3    Ceradini, D.4    Martin, S.R.5
  • 16
    • 0030861904 scopus 로고    scopus 로고
    • Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study
    • Smith MW, Dean M, Carrington M, Winkler C, Huttley GA, et al. (1997) Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study. Science 277: 959-965.
    • (1997) Science , vol.277 , pp. 959-965
    • Smith, M.W.1    Dean, M.2    Carrington, M.3    Winkler, C.4    Huttley, G.A.5
  • 17
    • 0037377309 scopus 로고    scopus 로고
    • Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses
    • Draenert R, Altfeld M, Brander C, Basgoz N, Corcoran C, et al. (2003) Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses. J Immunol Methods 275: 19-29.
    • (2003) J Immunol Methods , vol.275 , pp. 19-29
    • Draenert, R.1    Altfeld, M.2    Brander, C.3    Basgoz, N.4    Corcoran, C.5
  • 18
    • 0035862330 scopus 로고    scopus 로고
    • Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection
    • Altfeld M, Rosenberg ES, Shankarappa R, Mukherjee JS, Hecht FM, et al. (2001) Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J Exp Med 193: 169-180.
    • (2001) J Exp Med , vol.193 , pp. 169-180
    • Altfeld, M.1    Rosenberg, E.S.2    Shankarappa, R.3    Mukherjee, J.S.4    Hecht, F.M.5
  • 19
    • 0037302428 scopus 로고    scopus 로고
    • Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load
    • Addo MM, Yu XG, Rathod A, Cohen D, Eldridge RL, et al. (2003) Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. J Virol 77: 2081-2092.
    • (2003) J Virol , vol.77 , pp. 2081-2092
    • Addo, M.M.1    Yu, X.G.2    Rathod, A.3    Cohen, D.4    Eldridge, R.L.5
  • 20
    • 0030665257 scopus 로고    scopus 로고
    • Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia
    • Rosenberg ES, Billingsley JM, Caliendo AM, Boswell SL, Sax PE, et al. (1997) Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia. Science 278: 1447-1450.
    • (1997) Science , vol.278 , pp. 1447-1450
    • Rosenberg, E.S.1    Billingsley, J.M.2    Caliendo, A.M.3    Boswell, S.L.4    Sax, P.E.5
  • 21
    • 7844220992 scopus 로고    scopus 로고
    • The rate of CD4 decline as a determinant of progression to AIDS independent of the most recent CD4 count. The Italian Seroconversion Study
    • Cozzi Lepri A, Sabin CA, Phillips AN, Lee CA, Pezzotti P, et al. (1998) The rate of CD4 decline as a determinant of progression to AIDS independent of the most recent CD4 count. The Italian Seroconversion Study. Epidemiol Infect 121: 369-376.
    • (1998) Epidemiol Infect , vol.121 , pp. 369-376
    • Cozzi Lepri, A.1    Sabin, C.A.2    Phillips, A.N.3    Lee, C.A.4    Pezzotti, P.5
  • 22
    • 0037105728 scopus 로고    scopus 로고
    • Effect of prolonged discontinuation of successful antiretroviral therapy on CD4+ T cell decline in human immunodeficiency virus-infected patients: Implications for intermittent therapeutic strategies
    • Tebas P, Henry K, Mondy K, Deeks S, Valdez H, et al. (2002) Effect of prolonged discontinuation of successful antiretroviral therapy on CD4+ T cell decline in human immunodeficiency virus-infected patients: Implications for intermittent therapeutic strategies. J Infect Dis 186: 851-854.
    • (2002) J Infect Dis , vol.186 , pp. 851-854
    • Tebas, P.1    Henry, K.2    Mondy, K.3    Deeks, S.4    Valdez, H.5
  • 23
    • 1642339461 scopus 로고    scopus 로고
    • Effect of prolonged discontinuation of successful antiretroviral therapy on CD4 T cells: A controlled, prospective trial
    • Maggiolo F, Ripamonti D, Gregis G, Quinzan G, Callegaro A, et al. (2004) Effect of prolonged discontinuation of successful antiretroviral therapy on CD4 T cells: A controlled, prospective trial. AIDS 18: 439-446.
    • (2004) AIDS , vol.18 , pp. 439-446
    • Maggiolo, F.1    Ripamonti, D.2    Gregis, G.3    Quinzan, G.4    Callegaro, A.5
  • 24
    • 0034646143 scopus 로고    scopus 로고
    • HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors
    • Migueles SA, Sabbaghian MS, Shupert WL, Bettinotti MP, Marincola FM, et al. (2000) HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors. Proc Natl Acad Sci U S A 97: 2709-2714.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2709-2714
    • Migueles, S.A.1    Sabbaghian, M.S.2    Shupert, W.L.3    Bettinotti, M.P.4    Marincola, F.M.5
  • 25
    • 0006582115 scopus 로고    scopus 로고
    • Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection
    • Kaslow RA, Carrington M, Apple R, Park L, Munoz A, et al. (1996) Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection. Nat Med 2: 405-411.
    • (1996) Nat Med , vol.2 , pp. 405-411
    • Kaslow, R.A.1    Carrington, M.2    Apple, R.3    Park, L.4    Munoz, A.5
  • 26
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
    • Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, et al. (1996) Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 273: 1856-1862.
    • (1996) Science , vol.273 , pp. 1856-1862
    • Dean, M.1    Carrington, M.2    Winkler, C.3    Huttley, G.A.4    Smith, M.W.5
  • 27
    • 0035818046 scopus 로고    scopus 로고
    • Effect of coinfection with GB virus C on survival among patients with HIV infection
    • Xiang J, Wunschmann S, Diekema DJ, Klinzman D, Patrick KD, et al. (2001) Effect of coinfection with GB virus C on survival among patients with HIV infection. N Engl J Med 345: 707-714.
    • (2001) N Engl J Med , vol.345 , pp. 707-714
    • Xiang, J.1    Wunschmann, S.2    Diekema, D.J.3    Klinzman, D.4    Patrick, K.D.5
  • 29
    • 18744363385 scopus 로고    scopus 로고
    • HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus
    • Altfeld M, Allen TM, Yu XG, Johnston MN, Agrawal D, et al. (2002) HIV-1 superinfection despite broad CD8+T-cell responses containing replication of the primary virus. Nature 420: 434-439.
    • (2002) Nature , vol.420 , pp. 434-439
    • Altfeld, M.1    Allen, T.M.2    Yu, X.G.3    Johnston, M.N.4    Agrawal, D.5
  • 30
    • 0035198096 scopus 로고    scopus 로고
    • Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: Relationship to viral load in untreated HIV infection
    • Betts MR, Ambrozak DR, Douek DC, Bonhoeffer S, Brenchley JM, et al. (2001) Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: Relationship to viral load in untreated HIV infection. J Virol 75: 11983-11991.
    • (2001) J Virol , vol.75 , pp. 11983-11991
    • Betts, M.R.1    Ambrozak, D.R.2    Douek, D.C.3    Bonhoeffer, S.4    Brenchley, J.M.5
  • 31
    • 9144266646 scopus 로고    scopus 로고
    • Persistent recognition of autologous virus by high-avidity CD8 T cells in chronic, progressive human immunodeficiency virus type 1 infection
    • Draenert R, Verrill CL, Tang Y, Allen TM, Wurcel AG, et al. (2004) Persistent recognition of autologous virus by high-avidity CD8 T cells in chronic, progressive human immunodeficiency virus type 1 infection. J Virol 78: 630-641.
    • (2004) J Virol , vol.78 , pp. 630-641
    • Draenert, R.1    Verrill, C.L.2    Tang, Y.3    Allen, T.M.4    Wurcel, A.G.5
  • 32
    • 0037383592 scopus 로고    scopus 로고
    • Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
    • Wherry EJ, Blattman JN, Murali-Krishna K, van der Most R, Ahmed R (2003) Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J Virol 77: 4911-4927.
    • (2003) J Virol , vol.77 , pp. 4911-4927
    • Wherry, E.J.1    Blattman, J.N.2    Murali-Krishna, K.3    Van Der Most, R.4    Ahmed, R.5
  • 33
  • 34
    • 3142559470 scopus 로고    scopus 로고
    • HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8+ T cells producing both interferon-gamma and tumor-necrosis factor-alpha
    • Lichterfeld M, Yu XG, Waring MT, Mui SK, Johnston M, et al. (2004) HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8+ T cells producing both interferon-gamma and tumor-necrosis factor-alpha. Blood 104: 487-494.
    • (2004) Blood , vol.104 , pp. 487-494
    • Lichterfeld, M.1    Yu, X.G.2    Waring, M.T.3    Mui, S.K.4    Johnston, M.5
  • 35
    • 0036852179 scopus 로고    scopus 로고
    • HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
    • Migueles SA, Laborico AC, Shupert WL, Sabbaghian MS, Rabin R, et al. (2002) HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors. Nat Immunol 3: 1061-1068.
    • (2002) Nat Immunol , vol.3 , pp. 1061-1068
    • Migueles, S.A.1    Laborico, A.C.2    Shupert, W.L.3    Sabbaghian, M.S.4    Rabin, R.5
  • 36
    • 1642500367 scopus 로고    scopus 로고
    • Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: Changes after antiretroviral therapy
    • Harari A, Petitpierre S, Vallelian F, Pantaleo G (2004) Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: Changes after antiretroviral therapy. Blood 103: 966-972.
    • (2004) Blood , vol.103 , pp. 966-972
    • Harari, A.1    Petitpierre, S.2    Vallelian, F.3    Pantaleo, G.4
  • 37
    • 0347911962 scopus 로고    scopus 로고
    • HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity
    • Younes SA, Yassine-Diab B, Dumont AR, Boulassel MR, Grossman Z, et al. (2003) HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity. J Exp Med 198: 1909-1922.
    • (2003) J Exp Med , vol.198 , pp. 1909-1922
    • Younes, S.A.1    Yassine-Diab, B.2    Dumont, A.R.3    Boulassel, M.R.4    Grossman, Z.5
  • 38
    • 0036884096 scopus 로고    scopus 로고
    • Presence of HIV-1 Gag-specific IFN-gamma+IL-2+ and CD28+IL-2+ CD4 T cell responses is associated with nonprogression in HIV-1 infection
    • Boaz MJ, Waters A, Murad S, Easterbrook PJ, Vyakarnam A (2002) Presence of HIV-1 Gag-specific IFN-gamma+IL-2+ and CD28+IL-2+ CD4 T cell responses is associated with nonprogression in HIV-1 infection. J Immunol 169: 6376-6385.
    • (2002) J Immunol , vol.169 , pp. 6376-6385
    • Boaz, M.J.1    Waters, A.2    Murad, S.3    Easterbrook, P.J.4    Vyakarnam, A.5
  • 39
    • 0141677716 scopus 로고    scopus 로고
    • Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2
    • Iyasere C, Tilton JC, Johnson AJ, Younes S, Yassine-Diab B, et al. (2003) Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2. J Virol 77: 10900-10909.
    • (2003) J Virol , vol.77 , pp. 10900-10909
    • Iyasere, C.1    Tilton, J.C.2    Johnson, A.J.3    Younes, S.4    Yassine-Diab, B.5
  • 40
    • 0023233946 scopus 로고
    • Characteristics of the specific cell-mediated immune response in human immunodeficiency virus infection
    • Wahren B, Morfeldt-Mansson L, Biberfeld G, Moberg L, Sonnerborg A, et al. (1987) Characteristics of the specific cell-mediated immune response in human immunodeficiency virus infection. J Virol 61: 2017-2023.
    • (1987) J Virol , vol.61 , pp. 2017-2023
    • Wahren, B.1    Morfeldt-Mansson, L.2    Biberfeld, G.3    Moberg, L.4    Sonnerborg, A.5
  • 41
    • 0024567058 scopus 로고
    • Lymphocyte proliferative responses to human immunodeficiency virus antigens in vitro
    • Krowka JF, Stites DP, Jain S, Steimer KS, George-Nascimento C, et al. (1989) Lymphocyte proliferative responses to human immunodeficiency virus antigens in vitro. J Clin Invest 83: 1198-1203.
    • (1989) J Clin Invest , vol.83 , pp. 1198-1203
    • Krowka, J.F.1    Stites, D.P.2    Jain, S.3    Steimer, K.S.4    George-Nascimento, C.5
  • 43
    • 0034699512 scopus 로고    scopus 로고
    • Tatspecific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia
    • Allen TM, O'Connor DH, Jing P, Dzuris JL, Mothe BR, et al. (2000) Tatspecific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature 407: 386-390.
    • (2000) Nature , vol.407 , pp. 386-390
    • Allen, T.M.1    O'Connor, D.H.2    Jing, P.3    Dzuris, J.L.4    Mothe, B.R.5
  • 44
    • 0037122796 scopus 로고    scopus 로고
    • Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes
    • Barouch DH, Kunstman J, Kuroda MJ, Schmitz JE, Santra S, et al. (2002) Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature 415: 335-339.
    • (2002) Nature , vol.415 , pp. 335-339
    • Barouch, D.H.1    Kunstman, J.2    Kuroda, M.J.3    Schmitz, J.E.4    Santra, S.5
  • 45
    • 0035913225 scopus 로고    scopus 로고
    • Evolution and transmission of stable CTL escape mutations in HIV infection
    • Goulder PJ, Brander C, Tang Y, Tremblay C, Colbert RA, et al. (2001) Evolution and transmission of stable CTL escape mutations in HIV infection. Nature 412: 334-338.
    • (2001) Nature , vol.412 , pp. 334-338
    • Goulder, P.J.1    Brander, C.2    Tang, Y.3    Tremblay, C.4    Colbert, R.A.5
  • 46
    • 4344709657 scopus 로고    scopus 로고
    • Humoral immunity to HIV-1: Kinetics of antibody responses in chronic infection reflect capacity of immune system to improve viral set point
    • Trkola A, Kuster H, Leemann C, Oxenius A, Fagard C, et al. (2004) Humoral immunity to HIV-1: Kinetics of antibody responses in chronic infection reflect capacity of immune system to improve viral set point. Blood 104: 1784-1792.
    • (2004) Blood , vol.104 , pp. 1784-1792
    • Trkola, A.1    Kuster, H.2    Leemann, C.3    Oxenius, A.4    Fagard, C.5
  • 47
    • 10744220378 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 fitness is a determining factor in viral rebound and set point in chronic infection
    • Trkola A, Kuster H, Leemann C, Ruprecht C, Joos B, et al. (2003) Human immunodeficiency virus type 1 fitness is a determining factor in viral rebound and set point in chronic infection. J Virol 77: 13146-13155.
    • (2003) J Virol , vol.77 , pp. 13146-13155
    • Trkola, A.1    Kuster, H.2    Leemann, C.3    Ruprecht, C.4    Joos, B.5
  • 48
    • 0033803642 scopus 로고    scopus 로고
    • A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression
    • Quinones-Mateu ME, Ball SC, Marozsan AJ, Torre VS, Albright JL, et al. (2000) A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression. J Virol 74: 9222-9233.
    • (2000) J Virol , vol.74 , pp. 9222-9233
    • Quinones-Mateu, M.E.1    Ball, S.C.2    Marozsan, A.J.3    Torre, V.S.4    Albright, J.L.5
  • 49
    • 0242491896 scopus 로고    scopus 로고
    • Infection with multiple human immunodeficiency virus type 1 variants is associated with faster disease progression
    • Sagar M, Lavreys L, Baeten JM, Richardson BA, Mandaliya K, et al. (2003) Infection with multiple human immunodeficiency virus type 1 variants is associated with faster disease progression. J Virol 77: 12921-12926.
    • (2003) J Virol , vol.77 , pp. 12921-12926
    • Sagar, M.1    Lavreys, L.2    Baeten, J.M.3    Richardson, B.A.4    Mandaliya, K.5
  • 50
    • 0038806352 scopus 로고    scopus 로고
    • Enhanced detection of HIV-1-specific T cell responses to highly variable regions using peptides based on autologous virus sequences
    • Altfeld M, Addo MM, Shankarappac R, Lee PK, Allen TM, et al. (2003) Enhanced detection of HIV-1-specific T cell responses to highly variable regions using peptides based on autologous virus sequences. J Virol 77: 7330-7340.
    • (2003) J Virol , vol.77 , pp. 7330-7340
    • Altfeld, M.1    Addo, M.M.2    Shankarappac, R.3    Lee, P.K.4    Allen, T.M.5
  • 51
    • 0036841716 scopus 로고    scopus 로고
    • The functional CD8 T cell response to HIV becomes type-specific in progressive disease
    • Lee SK, Xu Z, Lieberman J, Shankar P (2002) The functional CD8 T cell response to HIV becomes type-specific in progressive disease. J Clin Invest 110: 1339-1347.
    • (2002) J Clin Invest , vol.110 , pp. 1339-1347
    • Lee, S.K.1    Xu, Z.2    Lieberman, J.3    Shankar, P.4
  • 52
    • 0035818544 scopus 로고    scopus 로고
    • Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects
    • Ortiz GM, Wellons M, Brancato J, Vo HT, Zinn RL, et al. (2001) Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects. Proc Natl Acad Sci U S A 98: 13288-13293.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13288-13293
    • Ortiz, G.M.1    Wellons, M.2    Brancato, J.3    Vo, H.T.4    Zinn, R.L.5
  • 53
    • 0033831645 scopus 로고    scopus 로고
    • Enhancement of human immunodeficiency virus type 1-specific CD4 and CD8 T cell responses in chronically infected persons after temporary treatment interruption
    • Papasavvas E, Ortiz GM, Gross R, Sun J, Moore EC, et al. (2000) Enhancement of human immunodeficiency virus type 1-specific CD4 and CD8 T cell responses in chronically infected persons after temporary treatment interruption. J Infect Dis 182: 766-775.
    • (2000) J Infect Dis , vol.182 , pp. 766-775
    • Papasavvas, E.1    Ortiz, G.M.2    Gross, R.3    Sun, J.4    Moore, E.C.5
  • 54
    • 0034749278 scopus 로고    scopus 로고
    • Transient mobilization of human immunodeficiency virus (HIV)-specific CD4 T-helper cells fails to control virus rebounds during intermittent antiretroviral therapy in chronic HIV type 1 infection
    • Carcelain G, Tubiana R, Samri A, Calvez V, Delaugerre C, et al. (2001) Transient mobilization of human immunodeficiency virus (HIV)-specific CD4 T-helper cells fails to control virus rebounds during intermittent antiretroviral therapy in chronic HIV type 1 infection. J Virol 75: 234-241.
    • (2001) J Virol , vol.75 , pp. 234-241
    • Carcelain, G.1    Tubiana, R.2    Samri, A.3    Calvez, V.4    Delaugerre, C.5
  • 55
    • 0035876068 scopus 로고    scopus 로고
    • The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection
    • Garcia F, Plana M, Ortiz GM, Bonhoeffer S, Soriano A, et al. (2001) The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection. AIDS 15: F29-F40.
    • (2001) AIDS , vol.15
    • Garcia, F.1    Plana, M.2    Ortiz, G.M.3    Bonhoeffer, S.4    Soriano, A.5
  • 56
    • 0042431969 scopus 로고    scopus 로고
    • Structured treatment interruption in patients with multidrug-resistant human immunodeficiency virus
    • Lawrence J, Mayers DL, Hullsiek KH, Collins G, Abrams DI, et al. (2003) Structured treatment interruption in patients with multidrug-resistant human immunodeficiency virus. N Engl J Med 349: 837-846.
    • (2003) N Engl J Med , vol.349 , pp. 837-846
    • Lawrence, J.1    Mayers, D.L.2    Hullsiek, K.H.3    Collins, G.4    Abrams, D.I.5
  • 57
    • 15744389046 scopus 로고    scopus 로고
    • Structured treatment interruptions in primary HIV infection: Final results of the multicenter prospective PRIMSTOP pilot trial
    • 2004 February 8-11; San Francisco, California
    • Hoen B, Fournier I, Charreau I, Lacabaratz C, Burgard M, et al. (2004) Structured treatment interruptions in primary HIV infection: Final results of the multicenter prospective PRIMSTOP pilot trial [abstract]. 11th Conference on Retroviruses and Opportunistic Infection; 2004 February 8-11; San Francisco, California. Available: http://www.retroconference.org/ 2004/cd/Abstract/395.htm. Accessed 15 September 2004.
    • (2004) 11th Conference on Retroviruses and Opportunistic Infection
    • Hoen, B.1    Fournier, I.2    Charreau, I.3    Lacabaratz, C.4    Burgard, M.5
  • 58
    • 2642541895 scopus 로고    scopus 로고
    • Evaluation of 2 therapeutic HIV vaccination regimens in HAART-treated primary HIV infection subjects following analytical treatment interruption: QUEST PROB3005, a randomized, placebo-controlled study
    • 2004 February 8-11; San Francisco, California
    • Kinloch S, Perrin L, Hoen B, Lampe F, Phillips A, et al. (2004) Evaluation of 2 therapeutic HIV vaccination regimens in HAART-treated primary HIV infection subjects following analytical treatment interruption: QUEST PROB3005, a randomized, placebo-controlled study [abstract]. 11th Conference on Retroviruses and Opportunistic Infection; 2004 February 8-11; San Francisco, California. Available: http://www.retroconference.org/ 2004/cd/Abstract/168.htm. Accessed 10 September 2004.
    • (2004) 11th Conference on Retroviruses and Opportunistic Infection
    • Kinloch, S.1    Perrin, L.2    Hoen, B.3    Lampe, F.4    Phillips, A.5
  • 59
    • 0038205366 scopus 로고    scopus 로고
    • Augmentation of HIV-1-specific T helper cell responses in chronic HIV-1 infection by therapeutic immunization
    • Robbins GK, Addo MM, Troung H, Rathod A, Haheeb K, et al. (2003) Augmentation of HIV-1-specific T helper cell responses in chronic HIV-1 infection by therapeutic immunization. AIDS 17: 1121-1126.
    • (2003) AIDS , vol.17 , pp. 1121-1126
    • Robbins, G.K.1    Addo, M.M.2    Troung, H.3    Rathod, A.4    Haheeb, K.5
  • 60
    • 0036192919 scopus 로고    scopus 로고
    • Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy
    • Rizzardi GP, Harari A, Capiluppi B, Tambussi G, Ellefsen K, et al. (2002) Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy. J Clin Invest 109: 681-688.
    • (2002) J Clin Invest , vol.109 , pp. 681-688
    • Rizzardi, G.P.1    Harari, A.2    Capiluppi, B.3    Tambussi, G.4    Ellefsen, K.5
  • 61
    • 0346850793 scopus 로고    scopus 로고
    • Predictors of plasma human immunodeficiency virus type 1 RNA control after discontinuation of highly active antiretroviral therapy initiated at acute infection combined with structured treatment interruptions and immunebased therapies
    • Lafeuillade A, Poggi C, Hittinger G, Counillon E, Emilie D (2003) Predictors of plasma human immunodeficiency virus type 1 RNA control after discontinuation of highly active antiretroviral therapy initiated at acute infection combined with structured treatment interruptions and immunebased therapies. J Infect Dis 188: 1426-1432.
    • (2003) J Infect Dis , vol.188 , pp. 1426-1432
    • Lafeuillade, A.1    Poggi, C.2    Hittinger, G.3    Counillon, E.4    Emilie, D.5
  • 62
    • 10744226358 scopus 로고    scopus 로고
    • A controlled trial of granulocyte macrophage-colony stimulating factor during interruption of HAART
    • Fagard C, Le Braz M, Gunthard H, Hirsch HH, Egger M, et al. (2003) A controlled trial of granulocyte macrophage-colony stimulating factor during interruption of HAART. AIDS 17: 1487-1492.
    • (2003) AIDS , vol.17 , pp. 1487-1492
    • Fagard, C.1    Le Braz, M.2    Gunthard, H.3    Hirsch, H.H.4    Egger, M.5
  • 63
    • 0034030697 scopus 로고    scopus 로고
    • Natural history of human immunodeficiency virus type 1 viremia after seroconversion and proximal to AIDS in a large cohort of homosexual men. Multicenter AIDS Cohort Study
    • Lyles RH, Munoz A, Yamashita TE, Bazmi H, Detels R, et al. (2000) Natural history of human immunodeficiency virus type 1 viremia after seroconversion and proximal to AIDS in a large cohort of homosexual men. Multicenter AIDS Cohort Study. J Infect Dis 181: 872-880.
    • (2000) J Infect Dis , vol.181 , pp. 872-880
    • Lyles, R.H.1    Munoz, A.2    Yamashita, T.E.3    Bazmi, H.4    Detels, R.5
  • 64
    • 4644249757 scopus 로고    scopus 로고
    • Loss of HIV-1-specific CD8+T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+T cells
    • Lichterfeld M, Kaufmann DE, Yu XG, Mui SK, Addo MM, et al. (2004) Loss of HIV-1-specific CD8+T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+T cells. J Exp Med 200: 701-712.
    • (2004) J Exp Med , vol.200 , pp. 701-712
    • Lichterfeld, M.1    Kaufmann, D.E.2    Yu, X.G.3    Mui, S.K.4    Addo, M.M.5


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