Restricting mobility of Gsα relative to the β2-adrenoceptor enhances adenylate cyclase activity by reducing Gsα GTPase activity

Biochemical Journal

Volumn 334, Issue 3, 1998, Pages 519-524

  Wenzel Seifert, Katharina ^a,c   Lee, Tae Weon ^a   Seifert, Roland ^a   Kobilka, Brian K ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA 2 ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; HYBRID PROTEIN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REPRESSION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; ANIMAL; ARMYWORM; BACULOVIRUS; BINDING SITE; CELL LINE; CHEMISTRY; COMPARATIVE STUDY; GENETICS; METABOLISM; MOLECULAR GENETICS;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; BINDING SITES; CELL LINE; ENZYME ACTIVATION; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GUANOSINE TRIPHOSPHATE; MOLECULAR SEQUENCE DATA; RECEPTORS, ADRENERGIC, BETA-2; RECOMBINANT FUSION PROTEINS; SPODOPTERA;

EID: 0032530265     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3340519     Document Type: Article

References (32)

1. Gilman, A. G. (1987) Annu. Rev. Biochem. 56, 615-649
2. Kobilka, B. K. (1992) Annu. Rev. Neurosci. 15, 87-114
3. Samama, P., Cotecchia, S., Costa, T. and Lefkowitz, R. J. (1993) J. Biol. Chem. 268, 4625-3636
4. Seifert, R., Wenzel-Seifert, K., Lee, T. W., Gether, U., Sanders-Bush, E. and Kobilka, B. K. (1998) J. Biol. Chem. 273, 5109-5116
5. Seifert, R., Lee, T. W., Lam, V. T. and Kobilka, B. K. (1998) Eur. J. Biochem., in the press
6. Brandt, D. R. and Ross, E. M. (1986) J. Biol. Chem. 261, 1656-1664
7. Gether, U., Lin, S. and Kobilka, B. K. (1995) J. Biol. Chem. 270, 28268-28275
8. Wieland, T. and Jakobs, K. H. (1994) Methods Enzymol. 237, 3-13
9. Bertin, B., Freissmuth, M., Jockers, R., Strosberg, A. D. and Marullo, S. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 8827-8831
10. Bertin, B., Jockers, R., Strosberg, A. D. and Marullo, S. (1997) Receptors Channels 5, 41-51
11. Kobilka, B. K., MacGregor, C., Daniel, K., Kobilka, T. S., Caron, M. G. and Letkowitz, R. J. (1987) J. Biol. Chem. 262, 15795-15802
12. Bouvier, M., Hausdorff, W. P., De Blasi, A., O'Dowd, B. F., Kobilka, B. K., Caron, M. G. and Lefkowitz, R. J. (1988) Nature (London) 333, 370-373
13. Wise, A., Carr, I. C. and Milligan, G. (1997) Biochem. J. 325, 17-21
14. Grünewald, S., Haase, W., Reiländer and Michel, H. (1996) Biochemistry 35, 15149-15161
15. Mouillac, B., Caron, M., Bonin, H., Dennis, M. and Bouvier, M. (1992) J. Biol. Chem. 267, 21733-21737
16. Samama, P., Pei, G., Costa, T., Cotecchia, S. and Lefkowitz, R. J. (1994) Mol. Pharmacol. 45, 390-394
17. Richardson, R. M. and Hosey, M.M (1992) J. Biol. Chem. 267, 22249-22255
18. Hamm, H. E. (1998) J. Biol. Chem. 273, 669-672
19. Biddlecome, G. H., Berstein, G. and Ross, E. M. (1996) J. Biol. Chem. 271, 7999-8007
20. Angleson, J. K. and Wensel, T. G. (1994) J. Biol. Chem. 269, 16290-16296
21. Berman, D. M., Wilkie, T. M. and Gilman, A. G. (1996) Cell 86, 445-452
22. Edidin, M., Kuo, S. C. and Sheetz, M. P. (1991) Science 254, 1379-1382
23. Kusumi, A., Sato, Y. and Yamamoto, M. (1993) Biophys. J. 65, 2021-2040
24. Saxton, M. J. (1993) Biophys. J. 64, 1766-1780
25. Neubig, R. R. (1994) FASEB J. 8, 939-946
26. Neer, E. J. (1995) Cell 80, 249-257
27. Beth, A. H., Conturo, T. E., Venkataramu, S. D. and Staros, J. V. (1986) Biochemistry 25, 3824-3832
28. Wang, N. and Rasenick, M. M. (1991) Biochemislry 30, 10957-10965
29. Särndahl, E., Bokoch, G. M., Noulay, F., Stendahl, O. and Andersson, T. (1996) J. Biol. Chem. 271, 15267-15271
30. Wieland, T., Meyer zu Heringdorf, D., Schulze, R., Kaldenberg-Stasch, S. and Jakobs, K. H. (1996) Eur. J. Biochem. 239, 752-758
31. Roychowdhury, S. and Rasenick, M. M. (1997) J. Biol. Chem. 272, 31576-31581
32. Leiber, D., Jasper, J. R., Alousi, A. A., Martin, J., Bernstein, D. and Insel, P. A. (1993) J. Biol. Chem. 268, 3833-3837