A new structural class of S-adenosylhomocysteine hydrolase inhibitors

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 18, 2009, Pages 6707-6714

  Kim, Byung Gyu ^a   Chun, Tae Gyu ^b   Lee, Hee Yoon ^b   Snapper, Marc L ^a  

^a BOSTON COLLEGE   (United States)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Ilimaquinone; Inhibitor; Pharmacophore modeling; S Adenosylhomocysteine hydrolase

Indexed keywords

ADENOSYLHOMOCYSTEINASE; ADENOSYLHOMOCYSTEINASE INHIBITOR; ILIMAQUINONE; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; COMPETITIVE INHIBITION; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITOR INTERACTION; MOLECULAR DOCKING; MOLECULAR MODEL; REACTION ANALYSIS; SPONGE (PORIFERA); STRUCTURE ACTIVITY RELATION;

ADENOSYLHOMOCYSTEINASE; ANIMALS; ANTI-INFECTIVE AGENTS; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; QUINONES; S-ADENOSYLHOMOCYSTEINE; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 69249106092     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.07.061     Document Type: Article

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